Lateralization of Sensory and Motor Functions in Human Neonates

1982 ◽  
Vol 54 (3_suppl) ◽  
pp. 1151-1158 ◽  
Author(s):  
Giovanni Cioni ◽  
Graziella Pellegrinetti

Lateral differences in some motor and sensory functions were examined in 89 full-term normal newborns, 2 to 4 days old. They were divided in two groups, according to the cerebral dominance in the family: Group A (70 subjects), offspring of right-handed parents and siblings, and Group B (19 subjects), with at least one parent or sibling left-handed or ambidextrous. Only subjects of Group A showed a marked tendency to spend more time with the head to right as opposed to the left, to turn right after release from the midline position, to have their heads right 5 min. later, to lead with the right leg on the placing response. The two groups were significantly different from each other on these tests. Differences were not observed for stepping, tactile responses, asymmetrical tonic neck reactions in either of the two groups. The results confirm the existence of lateral differentiations of neurological functions in the newborn and stress the presence of genetic factors in these phenomena.

Author(s):  
Jihane Ziati ◽  
Najlae El- Hafidi ◽  
Naima Bennani ◽  
Zineb Imane

Our study included 60 children with diabetes. We divided them into two groups: Group A and Group B. Patients assigned to Group A had controlled diabetes and formed our “Control Group”, while Group B was for patients with poorly controlled diabetes. This study was conducted in « The Home of the Young Diabetic » center in collaboration with the diabetes unit at the pediatric hospital of Rabat. Our goal was to identify the different predictors of metabolic control in diabetic adolescents by looking at the epidemiological data, lifestyle, social level, and the family life of different categories. Finally, we analyzed the results and suggested solutions. To improve the medical care of diabetes provide better control of the teenage period and reinforce therapeutic education, it is necessary to propose social help to families in need and expand the right of health insurance to all citizens but also refund all the new technologies in diabetes treatment. Lastly, we suggested the integration of a psychological test at the beginning of the diabetes discovery and add it to the screening of complications.


2019 ◽  
Vol 1 (4) ◽  
pp. 133-139
Author(s):  
Yasser Hamdy ◽  
Mohammed Mahmoud Mostafa ◽  
Ahmed Elminshawy

Background: Functional tricuspid valve regurgitation secondary to left-sided valve disease is common. DeVega repair is simple, but residual regurgitation with subsequent impairment of the right ventricular function is a concern. This study aims to compare tricuspid valve repair using DeVega vs. ring annuloplasty and their impact on the right ventricle in the early postoperative period and after six months. Methods: This is a prospective cohort study of 51 patients with rheumatic heart disease who underwent tricuspid valve repair for secondary severe tricuspid regurgitation. Patients were divided into two groups: group A; DeVega repair (n=34) and group B; ring annuloplasty repair (n=17). Patients were assessed clinically and by echocardiography before discharge and after six months for the degree of tricuspid regurgitation, right ventricular diameter and tricuspid annular plane systolic excursion (TAPSE). Results: Preoperative echocardiographic assessment showed no difference in left ventricular end-systolic diameter, end-diastolic diameter, ejection fraction and right ventricular diameter, however; group A had significantly better preoperative right ventricular function measured by TAPSE (1.96 ± 0.27 vs1.75 ± 0.31 cm; p=0.02). Group B had significantly longer cardiopulmonary bypass time (127.65 ± 13.56 vs. 111.74 ± 18.74 minutes; p= 0.003) and ischemic time (99.06 ± 11.80 vs. 87.15 ± 16.01 minutes; p= 0.009). Pre-discharge, there was no statistically significant difference in the degree of tricuspid regurgitation, but the right ventricular diameter was significantly lower in group B (2.66 ± 0.41 and 2.40 ± 0.48 cm; p=0.049). After six months of follow up, the degree of tricuspid regurgitation (p= 0.029) and the right ventricular diameter were significantly lower in the ring annuloplasty group (2.56 ± 0.39 and 2.29 ± 0.44 cm; p=0.029). Although there was a statistically significant difference in preoperative TAPSE, this difference disappeared after six months. Conclusion: Both DeVega and ring annuloplasty techniques were effective in the early postoperative period, ring annuloplasty was associated with lesser residual regurgitation and better right ventricular remodeling in severe functional tricuspid regurgitation than DeVega procedure after 6-months of follow up.


2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Emmanouil Chatzipetros ◽  
Spyros Damaskos ◽  
Konstantinos I. Tosios ◽  
Panos Christopoulos ◽  
Catherine Donta ◽  
...  

Abstract Background This study aims at determining the biological effect of 75/25 w/w nano-hydroxyapatite/chitosan (nHAp/CS) scaffolds on bone regeneration, in terms of fraction of bone regeneration (FBR), total number of osteocytes (Ost), and osteocyte cell density (CD), as well as its biodegradability. Methods Two critical-size defects (CSDs) were bilaterally trephined in the parietal bone of 36 adult Sprague-Dawley rats (18 males and 18 females); the left remained empty (group A), while the right CSD was filled with nHAp/CS scaffold (group B). Two female rats died postoperatively. Twelve, 11, and 11 rats were euthanized at 2, 4, and 8 weeks post-surgery, respectively. Subsequently, 34 specimens were resected containing both CSDs. Histological and histomorphometric analyses were performed to determine the FBR, calculated as [the sum of areas of newly formed bone in lateral and central regions of interest (ROIs)]/area of the original defect, as well as the Ost and the CD (Ost/mm2) in each ROI of both groups (A and B). Moreover, biodegradability of the nHAp/CS scaffolds was estimated via the surface area of the biomaterial (BmA) in the 2nd, 4th, and 8th week post-surgery. Results The FBR of group B increased significantly from 2nd to 8th week compared to group A (P = 0.009). Both the mean CD and the mean Ost values of group B increased compared to group A (P = 0.004 and P < 0.05 respectively). Moreover, the mean value of BmA decreased from 2nd to 8th week (P = 0.001). Conclusions Based on histological and histomorphometric results, we support that 75/25 w/w nHAp/CS scaffolds provide an effective space for new bone formation.


1994 ◽  
Vol 52 (2) ◽  
pp. 204-209 ◽  
Author(s):  
Ana Regina Caner-Cukiert ◽  
Arthur Cukiert

Dichotic listening tests have been being used in an increasing frequency to determine in a non-invasive way the cerebral dominance in right- and left-handed patients. This is especially relevant when surgery in eloquent brain areas is being contemplated. A Portuguese version of the dichotic words listening test was developed based mainly on Wexler's protocol. It consisted of 15 pairs of words with a stimulus dominance lower than 50%. They were recorded using natural voice and time and intensity synchronization by means of a specialized software. Each pair of words was presented twice in different channels within each block. The items were randomized and presented with a 300 msec interval between each trial. Four blocks of 30 pairs of words each were created, totalizing 120 trials. In the scoring process, the words heard over the right and left ears were wrote down. The number of times each word was heard over each ear was computed and their values subtracted yielding a partial score for each specific word pair. This process was repeated for all stimuli pair and a final score for right and left predominance was then reached. Thirty-two right handed normal individuals underwent the test 93.8% showed a right ear advantage. These results are very similar to the actual left hemisphere dominance rate in a right-handed population.


2017 ◽  
Vol 44 (2) ◽  
pp. 107-114 ◽  
Author(s):  
Zhengyu Bao ◽  
Hongwu Chen ◽  
Bing Yang ◽  
Michael Shehata ◽  
Weizhu Ju ◽  
...  

The efficacy of pulmonary vein antral isolation for patients with prolonged sinus pauses (PSP) on termination of atrial fibrillation has been reported. We studied the right atrial (RA) electrophysiologic and electroanatomic characteristics in such patients. Forty patients underwent electroanatomic mapping of the RA: 13 had PSP (group A), 13 had no PSP (group B), and 14 had paroxysmal supraventricular tachycardia (control group C). Group A had longer P-wave durations in lead II than did groups B and C (115.5 ± 15.4 vs 99.5 ± 10.9 vs 96.5 ± 10.4 ms; P=0.001), and RA activation times (106.8 ± 13.8 vs 99 ± 8.7 vs 94.5 ± 9.1 s; P=0.02). Group A's PP intervals were longer during adenosine triphosphate testing before ablation (4.6 ± 2.3 vs 1.7 ± 0.6 vs 1.5 ± 1 s; P &lt;0.001) and after ablation (4.7 ± 2.5 vs 2.2 ± 1.4 vs 1.6 ± 0.8 s; P &lt;0.001), and group A had more complex electrograms (11.4% ± 5.4% vs 9.3% ± 1.6% vs 5.8% ± 1.6%; P &lt;0.001). Compared with group C, group A had significantly longer corrected sinus node recovery times at a 400-ms pacing cycle length after ablation, larger RA volumes (100.1 ± 23.1 vs 83 ± 22.1 mL; P=0.04), and lower conduction velocities in the high posterior (0.87 ± 0.13 vs 1.02 ± 0.21 mm/ms; P=0.02) and high lateral RA (0.89 ± 0.2 vs 1.1 ± 0.35 mm/ms; P=0.04). We found that patients with PSP upon termination of atrial fibrillation have RA electrophysiologic and electroanatomic abnormalities that warrant post-ablation monitoring.


1993 ◽  
Vol 2 (6) ◽  
pp. 474-477 ◽  
Author(s):  
PA Shinners ◽  
MO Pease

OBJECTIVE: To compare hemodynamic measurements made before turning and at 5 and 30 minutes after turning, and to determine whether the stabilization period affects the difference between supine and side-lying pulmonary artery pressures. METHODS: This study was performed in the cardiothoracic surgical intensive care unit of a midwestern university hospital. The 31 postoperative open-heart surgical patients, 26 men and 5 women aged 41 to 76 years (64 +/- 9.3, mean +/- SD) with pulmonary artery catheters in place, were divided into two groups to compare supine to side-lying pressures and the time intervals between the position changes. The supine-first subjects (Group A) were placed in the supine position for baseline measurements and turned to either the right or left side-lying position for the 5- and 30-minute pulmonary artery pressure measurements. The side-first subjects (Group B) were placed in either the right or left side-lying position for baseline measurements and then in the supine position for the 5- and 30-minute pulmonary artery pressure measurements. RESULTS: Pulmonary artery pressures, heart rate and arterial pressure were not significantly different at 5 and 30 minutes. Supine pulmonary artery pressures in Group A were not significantly different from supine pressures in Group B. Side-lying pulmonary artery pressures in Group A were not significantly different from side-lying pressures in Group B. Side-lying vs supine pulmonary artery pressures were significantly different in both Group A and Group B. CONCLUSION: The current practice of turning and settling the patient, zeroing the transducer and proceeding to make the pulmonary artery pressure readings appears to be valid. The stabilization period after turning does not explain the differences found between side-lying and supine pulmonary artery pressures.


1980 ◽  
Vol 43 (10) ◽  
pp. 795-798 ◽  
Author(s):  
F. K. McKEITH ◽  
C. G. SMITH ◽  
T. R. DUTSON ◽  
J. W. SAVELL ◽  
R. L. HOSTETLER ◽  
...  

Fifteen carcasses, 10 from steers and 5 from cows, were used for the present study. Five steer carcasses (group A) were electrically stimulated as intact, unsplit carcasses. The left sides of 5 steer carcasses (group B) and of 5 cow carcasses (group C) were electrically stimulated; the right sides of the same 5 steer carcasses (group D) and of the same 5 cow carcasses (group E) were used as controls and were not electrically stimulated. Electrically stimulated carcasses and sides (groups A and B) had brighter, more youthful colored lean, less “heat-ring” and produced more tender and more palatable rib steaks than did control sides (group D). Electrical stimulation did not (P &gt; .05) affect ultimate pH or sarcomere length in steers or cows. Light and electron micrographs revealed increased (P &lt; .05) structural damage (more severe contracture bands) in steer or cow muscles from electrically stimulated sides than in muscles from control sides; however, structural damage was not (P &gt;.05) increased when intact steer carcasses were electrically stimulated and compared to unstimulated sides. Troponin-T was reduced in SDS gels of muscle from electrically stimulated, as compared to control, sides of cow carcasses (group C versus group E); no differences in percentage of protein subunits were observed between electrically stimulated and control sides of steer carcasses (group B versus group D). Electrical stimulation can be done on intact carcasses or sides of young beef to improve USDA lean maturity and lean color scores, to reduce “heat-ring” incidence and to improve tenderness.


1970 ◽  
Vol 9 (4) ◽  
pp. 204-207 ◽  
Author(s):  
Dilruba Siddiqua ◽  
Shamim Ara ◽  
Abu Sadat Mohammad Nurunnabi ◽  
Rukshana Ahmed ◽  
Ara Parven Hosne

Objective: A cross-sectional descriptive type of study was designed to find out the difference in weight of the right and left adrenal glands of Bangladeshi people in relation to age and to compare with the previous studies. Materials & Methods: The study was done in the Department of Anatomy, Dhaka Medical College, Dhaka from July 2008 to June 2009 and performed on 140 post mortem human adrenal glands collected from 70 unclaimed dead bodies which were in the morgue under examination in the Department of Forensic Medicine, Dhaka Medical College, Dhaka. The samples were divided into four age-groups including group A (11-20 years), group B (21-30 years), group C (31-40 years) & group D (41-60 years) and the weight of the adrenal glands were measured and recorded. Results: There was no difference found in weight in between the right and the left adrenal glands in any age group. For the right adrenal gland, the differences in weight between group A & group B and group A & group D were statistically significant (p<0.05). For the left adrenal gland, the differences in weight between group A & group D and group C & group D were statistically significant (p<0.05). Key words: Adrenal gland; weight of adrenal gland. DOI: 10.3329/bjms.v9i4.6686Bangladesh Journal of Medical Science Vol.09 No.4 July 2010 pp.204-207


2020 ◽  
Vol 9 (7) ◽  
pp. 394-401
Author(s):  
Sophie A. Blirup-Plum ◽  
Thomas Bjarnsholt ◽  
Henrik E. Jensen ◽  
Kasper N. Kragh ◽  
Bent Aalbæk ◽  
...  

Aims CERAMENT|G is an absorbable gentamicin-loaded biocomposite used as an on-site vehicle of antimicrobials for the treatment of chronic osteomyelitis. The purpose of the present study was to investigate the sole effect of CERAMENT|G, i.e. without additional systemic antimicrobial therapy, in relation to a limited or extensive debridement of osteomyelitis lesions in a porcine model. Methods Osteomyelitis was induced in nine pigs by inoculation of 104 colony-forming units (CFUs) of Staphylococcus aureus into a drill hole in the right tibia. After one week, the pigs were allocated into three groups. Group A (n = 3) received no treatment during the study period (19 days). Groups B (n = 3) and C (n = 3) received limited or extensive debridement seven days postinoculation, respectively, followed by injection of CERAMENT|G into the bone voids. The pigs were euthanized ten (Group C) and 12 (Group B) days after the intervention. Results All animals presented confirmatory signs of bone infection post-mortem. The estimated amount of inflammation was substantially greater in Groups A and B compared to Group C. In both Groups B and C, peptide nucleic acid fluorescence in situ hybridization (PNA FISH) of CERAMENT|G and surrounding bone tissue revealed bacteria embedded in an opaque matrix, i.e. within biofilm. In addition, in Group C, the maximal measured post-mortem gentamicin concentrations in CERAMENT|G and surrounding bone tissue samples were 16.6 μg/ml and 6.2 μg/ml, respectively. Conclusion The present study demonstrates that CERAMENT|G cannot be used as a standalone alternative to extensive debridement or be used without the addition of systemic antimicrobials. Cite this article: Bone Joint Res 2020;9(7):394–401.


1997 ◽  
Vol 5 (1) ◽  
pp. 20-24
Author(s):  
Fumikazu Nomura ◽  
Seiichiro Ikawa ◽  
Keishi Kadoba ◽  
Masataka Mitsuno ◽  
Yoshiki Sawa ◽  
...  

During a median follow-up period of 9 years (ranging from 9 months to 25 years), 24-hour ambulatory electrocardiographic studies were undertaken in 155 patients after repair of tetralogy of Fallot. The patients were divided into two groups. Group A consisted of 76 patients in whom the right ventricular approach was used and group B comprised 79 patients whose repair was through the right atrium. A transannular patch was employed in all patients in group A and in none of the patients in group B. Age at surgery was between 1 and 37 years (median age 4.8 years). During follow-up, 37 patients (48.6%) in group A had significant ventricular arrhythmias (Lown grade 2 or higher) and 13 patients (15.4%) in group B had significant ventricular arrhythmias. A close relationship was observed between age at surgery and Lown grade (R2 = 0.374, p < 0.001) and between follow-up duration and Lown grade (R2 = 0.514, p < 0.001), especially when the two groups were analyzed separately (R2 = 0.502, 0.476, p < 0.001). In contrast, no significant relationship was observed between the ratio of right ventricular to left ventricular pressure and Lown grade or between right ventricular systolic pressure and Lown grade. Discriminant analysis revealed risk factors associated with postoperative ventricular arrhythmias are follow-up duration (partial F = 3.22, p < 0.01), right ventricular to pulmonary artery pressure gradient (partial F = 3.35, p < 0.01), and operative method (partial F = 2.4, p < 0.05). Despite antiarrhythmic therapy, 11 of 22 late postoperative deaths occurred suddenly, presumably from ventricular arrhythmias. In this series of patients, the right atrial and pulmonary artery approach significantly reduced the risk of life-threatening ventricular arrhythmias after repair of tetralogy of Fallot.


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