scholarly journals Options for the formation of the psychosomatic spectrum disorders

2015 ◽  
Vol 22 (3) ◽  
pp. 40-41
Author(s):  
Д. Д. Krasnov
Keyword(s):  
Age Groups ◽  
Psychosomatic Disorders ◽  
Service Personnel ◽  
Somatic Health ◽  
Similar Range ◽  
Spectrum Disorders

On the ground of longstanding research (1986-2012) of mental and somatic health of service personnel and draft age personnel, belonging to different age groups, three variants of psychosomatic relations formation were determined in the examined people: dysontogenetic, psychoorganic and disadaptive. Each option defined both particular way of psychosomatic status development and similar range of psychosomatic disorders.

scholarly journals Cognitive Visual Dysfunctions in Children with Autism Spectrum Disorders and Other Developmental Delays

2020 ◽  
Author(s):  
Jin Kyung Seo ◽  
Young Hoon Kim ◽  
Eu Gene Park
Keyword(s):  
Autism Spectrum Disorders ◽  
Developmental Delays ◽  
Age Groups ◽  
Dorsal Stream ◽  
Visual Assessment ◽  
Autism Spectrum ◽  
Stream Functioning ◽  
The Mean ◽  
Spectrum Disorders ◽  
Social Communicative

Abstract Background: Autism spectrum disorders (ASD) are a group of neurodevelopmental disorders characterized by a triad of social, communicative, and imaginative impairments. Although early detection and intervention are important to improve functional outcomes in ASD, similar features between ASD and other developmental delays may impede timely diagnosis. In this study, we aimed to investigate the feasibility of Cognitive Visual Assessment Questionnaire (CVAQ) in differentiating ASD from other developmental delays.Methods: We retrospectively reviewed the medical records of 115 pediatric patients (80 males, 35 females) with ASD and other developmental delays who had the Modified Checklist for Autism in Toddlers (M-CHAT) and CVAQ performed at Uijeongbu St. Mary's Hospital from January 2017 to June 2019. Results: The mean age at M-CHAT and CVAQ was 31.8 months (range, 14.1 – 48). The proportion of ASD was significantly higher in patients with screen-positive M-CHAT than those with screen-negative M-CHAT (P = 0.035). The sensitivity of CVAQ for detecting ASD was 83.3% and 94.1% in 14.1 – <24 months and 24 – <36 months age groups, respectively. Among patients with screen-negative M-CHAT, the mean number of failed tasks related to dorsal stream pathway was greater in ASD compared to other developmental delays, although the differences were not statistically significant (P = 0.437).Conclusions: Our study demonstrates that autistic individuals may have a specific impairment in dorsal stream functioning. CVAQ also showed improved sensitivity for detecting ASD in toddlers. When coupled with clinical observation and judgement, CVAQ is a useful alternative screening tool for differentiating ASD from other developmental delays in young children.

scholarly journals Deficits in executive functions among youths with autism spectrum disorders: an age-stratified analysis

2016 ◽  
Vol 46 (8) ◽  
pp. 1625-1638 ◽  
Author(s):  
S.-F. Chen ◽  
Y.-L. Chien ◽  
C.-T. Wu ◽  
C.-Y. Shang ◽  
Y.-Y. Wu ◽  
...  
Keyword(s):  
Working Memory ◽  
Autism Spectrum Disorders ◽  
Spatial Working Memory ◽  
Digit Span ◽  
Age Groups ◽  
Autism Spectrum ◽  
Task Demands ◽  
Set Shifting ◽  
Spectrum Disorders ◽  
Stratified Analysis

BackgroundImpaired executive function (EF) is suggested to be one of the core features in individuals with autism spectrum disorders (ASD); however, little is known about whether the extent of worse EF in ASD than typically developing (TD) controls is age-dependent. We used age-stratified analysis to reveal this issue.MethodWe assessed 111 youths with ASD (aged 12.5 ± 2.8 years, male 94.6%) and 114 age-, and sex-matched TD controls with Digit Span and four EF tasks of the Cambridge Neuropsychological Test Automated Battery (CANTAB): Spatial Span (SSP), Spatial Working Memory (SWM), Stockings of Cambridge (SOC), and Intradimensional/Extradimensional Shift Test (I/ED).ResultsCompared to TD controls, youths with ASD performed poorer on the Digit Span, SWM, SOC, and I/ED tasks. The performance of all the tasks improved with age for both groups. Age-stratified analyses were conducted due to significant age × group interactions in visuospatial planning (SOC) and set-shifting (I/ED) and showed that poorer performance on these two tasks in ASD than TD controls was found only in the child (aged 8–12 years) rather than the adolescent (aged 13–18 years) group. By contrast, youths with ASD had impaired working memory, regardless of age. The increased magnitude of group difference in visuospatial planning (SOC) with increased task demands differed between the two age groups but no age moderating effect on spatial working memory.ConclusionsOur findings support deficits in visuospatial working memory and planning in youths with ASD; however, worse performance in set-shifting may only be demonstrated in children with ASD.

scholarly journals Structural Features of Glands in the Sphincter Zones of the Large Intestine of an Adult

2021 ◽  
Vol 10 (4) ◽  
pp. 9-13
Author(s):  
D. B. Nikityuk ◽  
V. M. Chuchkov ◽  
N. N. Chuchkova ◽  
N. T. Alexeeva ◽  
S. V. Klochkova
Keyword(s):  
Epithelial Cells ◽  
Large Intestine ◽  
Picric Acid ◽  
Age Groups ◽  
Longitudinal Section ◽  
Structural Features ◽  
Intestinal Wall ◽  
Cellular Composition ◽  
Parametric Statistics ◽  
Similar Range

The aim is to study macro- and microscopic structure, as well as the cellular composition of the glands of the sphincter zones of large intestine of adults of different age groups.Material and methods. On autopsy material obtained from 30 people, without signs of pathology of the digestive tract of three age groups: 20–29 years, 50–59 years, 90–99 years, the structure of the glandular apparatus of the sphincter zones was studied. The areas of the Gerlach flap, Girsch sphincters, Payr–Strauss, Bally, O'bern–Pirogov–Moutier were considered. Quantitative morphometry was performed on histological preparations stained with methylene blue, followed by fixation in a saturated solution of ammonium molybdenum (picric acid), hematoxylin-eosin, picrofuchsin according to Van Gieson. Methods of parametric statistics based on the Statistica 6.0 program were used for statistical data processing.Results. The analysis of the number, size and cellular composition of the glands of the sphincter zones of the large intestine revealed an increase in both the number of glands and their size in all age groups compared to the proximally adjacent areas of the intestine, on average by 1.3–1.5 times. In a similar range, individual indicators of the number of epithelial cells in the glands of the sphincter zones of the colon increased. At the same time, the cellular composition of the glands of the sphincter zones and adjacent areas of the intestinal wall was similar to neighboring areas, with predominant goblet-shaped epithelial cells (52.9–54.2% of cells on the longitudinal section of the gland) and the presence of absorption cells (29.9–31.2%), undifferentiated – 11.9–13.2% and argyrophilic endocrinocytes – 1.4–5.3%.Conclusion. Against the background of narrowing of the lumen of the large intestine in the area of the sphincters and changes in the nature of the mucous membrane, there is an increase in the size and density of the localization of glands in all age groups. This confirms the thesis about the formation of a protective barrier that provides a local adaptive potential of this area of the intestinal wall, against the background of increased mechanical effects of intestinal masses.

Fetal Alcohol Spectrum Disorders

2010 ◽  
Author(s):  
John C. Thorne ◽  
Tracy Jirikowic
Keyword(s):  
Fetal Alcohol Syndrome ◽  
Fetal Alcohol Spectrum Disorders ◽  
Alcohol Exposure ◽  
Fetal Alcohol ◽  
Growth Deficiency ◽  
Facial Phenotype ◽  
History Of ◽  
Similar Range ◽  
Spectrum Disorders ◽  
Fetal Alcohol Spectrum

Fetal alcohol spectrum disorders (FASD) is an umbrella term used to refer to the range of negative outcomes associated with prenatal ethyl-alcohol exposure (PAE). Although the impact of maternal drinking on the pre and postnatal development of children was examined as early as the late 19th century (Sullivan 1899), the teratogenic effects of PAE were not widely recognized until 1973, when Jones and Smith discussed PAE. The fetal alcohol syndrome (FAS) they described is now recognized internationally as a permanent birth defect syndrome resulting from PAE. Fetal alcohol syndrome is characterized by growth deficiency, a unique cluster of three minor facial anomalies, and evidence of central nervous system (CNS) abnormalities. At an estimated prevalence of one to three cases per 1,000 live births, FAS is the leading known preventable cause of developmental and intellectual disabilities (Bailey and Sokol 2008). Because the distinctive FAS facial phenotype provides a specific diagnostic marker of PAE (Astley 2006), FAS is the most readily recognized of the FASD. Fetal alcohol spectrum disorders that lack the tell-tale facial phenotype of FAS are more difficult to diagnose, but share a similar range and severity of CNS impairments and social costs. Other FASDs are many times more prevalent than FAS (Bailey and Sokol 2008) and may occur in as many as 1% of all children. Along with CNS, craniofacial, and growth impairments, FASD may also include ophthalmologic, cardiac, renal, and orthopedic abnormalities. Although heavier PAE, particularly binge drinking, leads to increased risk of FASD, no safe exposure level has been established. It is apparent that risk is substantially increased if the mother is older, has a history of alcoholism, has a family history of FASD, or is living in poverty. However, no clear set of risk or protective factors has been determined for any FASD that would allow for evidence-based advice to a particular mother on the relative risk that a particular level of drinking might have on her child’s development (Bailey and Sokol 2008; Jacobson et al. 2004; Maier and West 2001; Nulman et al. 2004; see also Disney et al. 2008).

Evaluation and Comparison of Psychometric Instruments for Pediatric Bipolar Spectrum Disorders in Four Age Groups

2007 ◽  
Vol 17 (6) ◽  
pp. 853-866 ◽  
Author(s):  
Thomas W. Frazier ◽  
Christine A. Demeter ◽  
Eric A. Youngstrom ◽  
Joseph R. Calabrese ◽  
Robert J. Stansbrey ◽  
...  
Keyword(s):  
Age Groups ◽  
Bipolar Spectrum ◽  
Bipolar Spectrum Disorders ◽  
Psychometric Instruments ◽  
Spectrum Disorders

scholarly journals HEALTH STATUS OF INSTRUCTIONAL STAFF OF HIGHER EDUCATION INSTITUTIONS WITH SPECIAL TRAINING CONDITIONS

2021 ◽  
Vol 74 (1) ◽  
pp. 122-127
Author(s):  
Serhii V. Rusanivskyi ◽  
Oleksii S. Fedchenko ◽  
Oleksandr M. Kruk ◽  
Serhii A. Oleksiychyk ◽  
Ruslan V. Lysyk ◽  
...  
Keyword(s):  
Higher Education ◽  
Police Officers ◽  
Higher Education Institutions ◽  
Current System ◽  
Age Groups ◽  
Somatic Health ◽  
Training Conditions ◽  
Special Training ◽  
Observation Methods ◽  
Instructional Staff

The aim is to study the level and dynamics of instructor officers’ somatic health during the course of employment at Ukrainian higher education institutions with special training conditions Materials and methods: The study involved male instructor officers of the National Academy of Internal Affairs (Kyiv, Ukraine) of different age groups (n=103), who conduct training sessions with cadets – future police officers. The first age group (up to 25 years of age) comprised 8 instructors, the second one (26-30 years of age) – 11 instructors, the third one (31-35 years of age) – 14 instructors, the fourth one (36-40 years of age) – 16 instructors, the fifth one (41-45 years of age) – 19 instructors, the sixth one(46-50 years of age) – 17 instructors, and the seventh one (over 50 years of age) – 18 instructors. The study was conducted in 2017-2019. The level of instructor officers’ health was examined according to the methodology of G. L. Apanasenko, which provides for the calculation of body mass, vital, strength, and Robinson indices, as well as the duration of recovery of heart rate after standard exercise. The research methods: theoretical analysis and generalization of literature sources, pedagogical testing and observation, methods of mathematical statistics. Results: Insufficient level of health was revealed among instructor officers of all age groups – the level of somatic health of the vast majority of instructional staff (over 75 %) is assessed as “low” and “below average”, more than 95 % of instructors are below the “safe zone” according to the methodology of G. L. Apanasenko. Conclusions: The research shows that the current system of physical training of higher education institutions with special training conditions is ineffective and needs to be refined in order to strengthen the health of instructor officers, increase their efficiency and, in general, improve the effectiveness of training future police officers at higher education institutions.

Problem behavior in autism spectrum disorders: A paradigmatic self-organized perspective of network structures

2019 ◽  
Vol 42 ◽  
Author(s):  
Lucio Tonello ◽  
Luca Giacobbi ◽  
Alberto Pettenon ◽  
Alessandro Scuotto ◽  
Massimo Cocchi ◽  
...  
Keyword(s):  
Autism Spectrum Disorder ◽  
Problem Behaviors ◽  
Autism Spectrum ◽  
The Self ◽  
Network Structures ◽  
Self Organized ◽  
Critical Equilibrium ◽  
Self Organized Criticality ◽  
Acute Agitation ◽  
Spectrum Disorders

AbstractAutism spectrum disorder (ASD) subjects can present temporary behaviors of acute agitation and aggressiveness, named problem behaviors. They have been shown to be consistent with the self-organized criticality (SOC), a model wherein occasionally occurring “catastrophic events” are necessary in order to maintain a self-organized “critical equilibrium.” The SOC can represent the psychopathology network structures and additionally suggests that they can be considered as self-organized systems.

An Ultrastructural Study of the Proliferation Patterns of the Reserve Cells of the Human Cervix Uteri

1972 ◽  
Vol 30 ◽  
pp. 80-81
Author(s):  
Takanori Sohda ◽  
Hiroshi Saito ◽  
Goro Asano ◽  
Katsunari Fukushi ◽  
Katsuya Suzuki ◽  
...  
Keyword(s):  
Ultrastructural Study ◽  
Age Groups ◽  
Point Of View ◽  
University Hospital ◽  
Cervix Uteri ◽  
Morphological Aspect ◽  
Functional Aspect ◽  
Pathological Conditions ◽  
Human Cervix ◽  
Morphological Patterns

Recently, the functional aspect as well as morphological aspect of the reserve cells in the cervix uteri drew much attention in view of the carcinogenesis in squamocolumunar junction. In this communication, the authors elucidate the ultrastructural features of the reserve cells in patients of various age groups visiting our university hospital and affiliated hospital.From conventional light microscopic point of view, the reserve cells tend to be pronounced in various pathological conditions, such as the persisting inflammation, proliferative disorders and irritation of hormones. The morphological patterns of the reserve cells from various stage and degree of irritation were observed.

Effects of aging on axon terminals in the dentate molecular layer

1987 ◽  
Vol 45 ◽  
pp. 928-929
Author(s):  
K. Cullen-Dockstader ◽  
E. Fifkova
Keyword(s):  
Granule Cells ◽  
Molecular Layer ◽  
Age Groups ◽  
Long Term Potentiation ◽  
Male Rats ◽  
Perforant Path ◽  
Axon Terminals ◽  
Fischer 344 ◽  
Spatial Memory Deficit ◽  
Effects Of Aging

Normal aging results in a pronounced spatial memory deficit associated with a rapid decay of long-term potentiation at the synapses between the perforant path and spines in the medial and distal thirds of the dentate molecular layer (DML), suggesting the alteration of synaptic transmission in the dentate fascia. While the number of dentate granule cells remains unchanged, and there are no obvious pathological changes in these cells associated with increasing age, the density of their axospinous contacts has been shown to decrease. There are indications that the presynaptic element is affected by senescence before the postsynaptic element, yet little attention has been given to the fine structure of the remaining axon terminals. Therefore, we studied the axon terminals of the perforant path in the DML across three age groups.5 Male rats (Fischer 344) of each age group (3, 24 and 30 months), were perfused through the aorta.

RTS,S/AS01, a vaccine targeting pre-erythrocytic stages of Plasmodium falciparum

2017 ◽  
Vol 1 (6) ◽  
pp. 533-537
Author(s):  
Lorenz von Seidlein ◽  
Borimas Hanboonkunupakarn ◽  
Podjanee Jittmala ◽  
Sasithon Pukrittayakamee
Keyword(s):  
Protective Efficacy ◽  
Age Groups ◽  
Sub Saharan Africa ◽  
Phase Iii ◽  
European Medicines Agency ◽  
Older Children ◽  
Pivotal Phase ◽  
Malaria Epidemiology ◽  
Maximum Benefit ◽  
Sub Saharan

RTS,S/AS01 is the most advanced vaccine to prevent malaria. It is safe and moderately effective. A large pivotal phase III trial in over 15 000 young children in sub-Saharan Africa completed in 2014 showed that the vaccine could protect around one-third of children (aged 5–17 months) and one-fourth of infants (aged 6–12 weeks) from uncomplicated falciparum malaria. The European Medicines Agency approved licensing and programmatic roll-out of the RTSS vaccine in malaria endemic countries in sub-Saharan Africa. WHO is planning further studies in a large Malaria Vaccine Implementation Programme, in more than 400 000 young African children. With the changing malaria epidemiology in Africa resulting in older children at risk, alternative modes of employment are under evaluation, for example the use of RTS,S/AS01 in older children as part of seasonal malaria prophylaxis. Another strategy is combining mass drug administrations with mass vaccine campaigns for all age groups in regional malaria elimination campaigns. A phase II trial is ongoing to evaluate the safety and immunogenicity of the RTSS in combination with antimalarial drugs in Thailand. Such novel approaches aim to extract the maximum benefit from the well-documented, short-lasting protective efficacy of RTS,S/AS01.

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