scholarly journals The marketing study of the pharmaceutical market of Ukraine in the segment of antihemorrhagic agents to stop dental bleeding

2021 ◽  
Vol 7 (3) ◽  
pp. 73-82
Author(s):  
I. S. Laba ◽  
Yu. M. Azarenko ◽  
O. М. Ievtushenko
Keyword(s):  
Bacterial Flora ◽  
Marketing Research ◽  
Pharmaceutical Market ◽  
New Drugs ◽  
Similar Action ◽  
Hemostatic Agents ◽  
Hemostatic Effect ◽  
Scientific Issue ◽  
Marketing Analysis ◽  
Active Substances

Aim. To conduct the marketing research of the Ukrainian market in the segment of antihemorrhagic agents used in dentistry.Materials and methods. The study was performed using the structural analysis, logical and graphical methods, marketing analysis methods.Results. The state of the Ukrainian market of drugs of this group has been determined. The market structure has been revealed in the number of names, brands, in forms of production, manufacturers, composition. Despite the sufficient number of registered drugs at the market (26 positions), a rather small arsenal  of active substances (4) and dosage forms (3) can be observed. The market is characterized by a limited amount of drugs with a certain pharmacodynamics combining a rapid hemostatic effect, safety in use, the ability to suppress bacterial flora, and without the effect on healthy tissues. However, a positive moment should be noted: by the structure of manufacturer countries the market remains domestic (60 : 40).Conclusions. The Ukrainian pharmaceutical market is characterized by a sufficient assortment of hemostatic agents, but the use of these drugs in dentistry has its limitations. Dental doctors have certain problems with the occurrence of capillary bleeding and require a sufficient amount of effective and fastacting drugs for local application. Therefore, the search and creation of new drugs with a similar action at this stage remains a relevant scientific issue.

scholarly journals MARKETING ANALYSIS OF THE ASSORTMENT OF DRUGS FOR THE TREATMENT OF HERPES VIRAL DISEASES AT THE PHARMACEUTICAL MARKET OF UKRAINE

2020 ◽  
Vol 3 ◽  
pp. 70-76
Author(s):  
Lydmila Kienko ◽  
Vita Hrytsenko ◽  
Larysa Iakovlieva ◽  
Larysa Bobrytska
Keyword(s):  
Skin Diseases ◽  
Marketing Research ◽  
Antiviral Effect ◽  
Dosage Forms ◽  
Pharmaceutical Market ◽  
New Drugs ◽  
Viral Diseases ◽  
Sources Of Information ◽  
Marketing Analysis ◽  
Official Sources

Nowadays there is a tendency towards the spread of viral diseases that cause significant complications to human health. Therefore, the question of creating new drugs that have a high antiviral effect is topical. The aim. To study the range of drugs in Ukraine for the treatment of herpes viral diseases. Materials and methods. In the work were used the list of drugs from official sources of information, which were processed by methods of generalization, systematization, graphic, comparative and structural analysis. Results and discussion. The marketing research of drugs for the treatment of herpes viral diseases presented at the pharmaceutical market of Ukraine has been conducted. According to the results it is found that 80 drugs for the treatment of herpes viral diseases of various dosage forms are presented in the domestic market, of which 70 % – tablets; 51 % – medicines produced by the industry of Ukraine; 94 % – are monocomponent preparations. Soft drugs play important role in the treatment of skin diseases because they provide a direct effect of the drugs on the pathogens, eliminate inflammatory phenomena and eliminate or reduce the symptoms of the disease. Soft dosage drugs have practically no contraindications, they can be used at any age, regardless of the presence of comorbidities. Conclusions. Domestic drugs (51 % of the total range) dominate in the market structure. The main part (94 %) consist of monocomponent preparations. The results of the research prove the relevance of the development of new combined soft dosage forms for the treatment of herpes viral diseases, which should be produced by the Ukrainian industry and satisfy the medical and economical needs of patients. The results of the marketing analysis show that it is relevant and promising to create new combined the soft dosage forms for the treatment of herpes viral diseases.

scholarly journals The marketing analysis of the market of medicines for the treatment of the wound process and burn disease at the hospital stage in the military personnel

2021 ◽  
Vol 7 (1) ◽  
pp. 71-79
Author(s):  
V. O. Tarasenko ◽  
O. P. Shmatenko ◽  
P.S. Syrota ◽  
O.V. Myropolska ◽  
V.V. Shmatenko
Keyword(s):  
Wound Healing ◽  
Military Personnel ◽  
Marketing Research ◽  
Pharmaceutical Market ◽  
Antifungal Drugs ◽  
Foreign Production ◽  
Marketing Analysis ◽  
Soft Drug ◽  
Burn Disease ◽  
The Military

Aim. To summarize the list of medicines that can be used at various stages of the treatment of burn disease and wound healing at the hospital stage in the military personnel; conduct the marketing analysis of the Ukrainian market of these medicines in order to determine the feasibility of creating an ointment for the treatment of inflammatory skin diseases and burns. Materials and methods. The study objects were the “State Register of Medicinal Products of Ukraine” information and search system and the Compendium. When conducting our studies the following scientific and system-review methods of the information search were used: bibliographic, documentary, content analysis, comparison method, system analysis, marketing research. Results. As a result of the study of the range of drugs for wound healing presented at the pharmaceutical market of Ukraine, it has been found that 64 % are drugs of the Ukrainian production, foreign drugs are 36 %. The distribution of soft drug forms registered in Ukraine has been carried out by pharmacological groups; it has been found that the percentage of antimicrobial and antifungal drugs is almost the same (15.8 % and 15.2 %, respectively). Steroidal anti-inflammatory drugs predominate over nonsteroidal ones (14.9 % and 11.4 %, respectively). The studies conducted have shown that at the domestic market there are many drugs of foreign production, which have no Ukrainian analogs. The marketing research has shown that combined drugs are more effective for the treatment of burns. They act simultaneously in several directions and facilitate the healing process. Among the drugs considered combined medicines occupy 42 %, while the share of monocomponent drugs is 58 %. The amount of synthetic drugs is 88 % and significantly exceeds the number of herbal medicines (12 %). Conclusions. The concept and methodology for the treatment of burns are summarized. It has been determined that the drugs of choice are complex soft drug forms. As a result of the marketing research on the structure and nomenclature of soft drug forms it has been found that at the domestic pharmaceutical market soft drug forms of foreign production is 36 %, and domestic ones – 64 %. It has been determined that the number of drugs for local wound healing is about 6 % of the total range of soft drug forms and presented mainly by monocomponent drugs (58 %). The analysis of the range of drugs with the anti-burn and antiseptic action by dosage forms has shown that ointments are the largest share – 67%, drugs in the form of creams – 18%. Key words: marketing analysis; servicemen; burn disease; wound process; hospital stage of treatment.

1,2,3-Triazole- and Quinoline-Based Hybrids with Potent Antiplasmodial Activity

2021 ◽  
Vol 18 ◽  
Author(s):  
Isabela A. Graciano ◽  
Alcione S. de Carvalho ◽  
Fernando de Carvalho da Silva ◽  
Vitor F. Ferreira
Keyword(s):  
Antimalarial Activity ◽  
Biological Activities ◽  
Review Article ◽  
Pharmaceutical Market ◽  
Biologically Active ◽  
New Drugs ◽  
Synthetic Methods ◽  
Antiplasmodial Activity ◽  
New Chemical Entities ◽  
Active Substances

Background: Malaria is a disease causing millions of victims every year and requires new drugs, often due to parasitic strain mutations. Thus, the search for new molecules that possess antimalarial activity is constant and extremely important. However, the potential that an antimalarial drug possesses cannot be ignored, and molecular hybridization is a good strategy to design new chemical entities. Objective: This review article aims to emphasize recent advances in the biological activities of new 1,2,3-triazole- and quinoline-based hybrids and their place in the development of new biologically active substances. More specifically, it intends to present the synthetic methods that have been utilized for the syntheses of hybrid 1,2,3-triazoles with quinoline nuclei. Method: We have comprehensively and critically discussed all the information available in the literature regarding 1,2,3-triazole- and quinoline-based hybrids with potent antiplasmodial activity. Results: The quinoline nucleus has already been proven to lead to new chemical entities in the pharmaceutical market, such as drugs for the treatment of malaria and other diseases. The same can be said about the 1,2,3-triazole heterocycle, which has been shown to be a beneficial scaffold for the construction of new drugs with several activities. However, only a few triazoles have entered the pharmaceutical market as drugs. Conclusion: Many studies have been conducted to develop new substances that may circumvent the resistance developed by the parasite that causes malaria, thereby improving the therapy currently used.

scholarly journals Marketing analysis of some groups antidiabetic medicines, presented at pharmaceutical market of Ukraine

2018 ◽  
pp. 3-11
Author(s):  
I. V. Vyshnytska ◽  
V. V. Trokhymchuk
Keyword(s):  
Outpatient Treatment ◽  
Type Ii Diabetes ◽  
Marketing Research ◽  
Pharmaceutical Market ◽  
Demographic Situation ◽  
The Social ◽  
Marketing Analysis ◽  
The Subject ◽  
The Cost ◽  
Real State

The scarcity of state resources, the social economic and demographic situation, the deterioration of health status of population require new state approaches of organizing  medical and pharmaceutical provision for the population. The aim of the study is the drug supply for patients with type ІІ diabetes. Relevance of theme is determined by the prevalence of the disease, the development of complex concomitant diseases, complications, early disability and high mortality due to low-quality and untimely medical and pharmaceutical care for this category of patients. The object of marketing research was the drugs registered in Ukraine, which cost is the subject to reimbursement for outpatient treatment of patients with type ІІ diabetes by the conditions of March 2017. The search for the proposals of drugs under study on the website of Morion Company was also conducted to assess the real state of the pharmaceutical market on this issue. The main used methods are bibliographic, statistical, marketing, graphic and systematization. The Ukrainian pharmaceutical market of drugs with the cost, which is the subject to reimbursement for outpatient treatment of patients with type II diabetes,   has been investigated, and found that Gliclazide and Metformin are registered on the territory of Ukraine in the form of 22 and 91 medicines, respectively. The part of domestic producers of Gliclazide and Metformin is 36% and 33%, respectively. It was revealed, that the assortment of drugs Gliclazide and Metformin, which are available in the pharmacy network, is 2 and 1.4 times less than registered in Ukraine, respectively. Gliclazide and Metformin tablets are offered by domestic and foreign manufacturers in a dosage of 30 mg, 60 mg, 80 mg and 500 mg, 800 mg, 1 000 mg, respectively.

Impact of generic entry to off-patent branded medicines in Japanese pharmaceutical market

2017 ◽  
Vol 13 (3) ◽  
pp. 114-122 ◽  
Author(s):  
Daigo Fukumoto ◽  
Takeshi Suzuki
Keyword(s):  
Price Competition ◽  
Health Care Expenditures ◽  
Pharmaceutical Market ◽  
New Drugs ◽  
Market Penetration ◽  
Generic Medicines ◽  
Generic Entry ◽  
Factors Associated ◽  
Corporate Strategies ◽  
Patent Medicines

The Japanese pharmaceutical market is known for having a relatively low market penetration of generic medicines. However, the velocity of generic penetration varies among medicines. Looking at current sales and share of off-patent branded medicines and generic medicines in Japanese pharmaceutical market, our main aim is to identify the factors associated with sales reductions of off-patent medicines and price competition caused by generic entry in the Japanese pharmaceutical market. We showed as one result that an increase in the number of generic maker entries significantly increases both price competition and sales reductions of off-patent branded medicines. As a second factor of note, we found that being subject to “NHI Drug Price Premium for Promoting the Creation of New Drugs and the Elimination of Off-label Use” before generic entry is related to maintaining sales of off-patent branded medicines after generic entry. The importance of generic medicines is increasing in association with the hypertrophy of health care expenditures in Japan. Efficient polices and corporate strategies reflecting market principles are strongly needed. Detailed results of this study on what determines whether sales and prices of off-patent medicines significantly decrease after generic entry in the Japanese pharmaceutical market should be useful for this purpose.

scholarly journals ИЗУЧЕНИЕ ГЕМОСТАТИЧЕСКОЙ АКТИВНОСТИ КРОВООСТАНАВЛИВАЮЩИХ ИМПЛАНТОВ В ЭКСПЕРИМЕНТЕ IN VITRO

Innova ◽  
2019 ◽  
Vol 17 (4) ◽  
pp. 6-9
Author(s):  
В.А Липатов ◽  
К.А. Сотников ◽  
Д.А. Северинов ◽  
М.В. Косоголов ◽  
С.Г. Писковитина ◽  
...  
Keyword(s):  
Comparative Analysis ◽  
Blood Clot ◽  
Collagen Sponge ◽  
New Drugs ◽  
Coagulation Time ◽  
Surgical Interventions ◽  
Hemostatic Agents ◽  
In Vitro Experiment ◽  
Hemostatic System

Stopping bleeding during injuries, planned and emergency surgical interventions is a difficult and not completely resolved problem. Accordingly, in modern surgery, the most promising direction is the development of new drugs that affect the hemostatic system and locally acting hemostatic agents. This article presents the results of the research on the comparative analysis of the ability of application hemostatic agents to form a blood clot in the in vitro experiment. The hemostatic properties of the following agents were studied: sponge implants based on sodium salt of carboxymethyl cellulose in two versions: unmodified and thermostabilized, hemostatic collagen sponge, and «Tachocomb» hemostatic sponge. The experiment was performed using stabilized blood citrate of 10 volunteer donors, which was recalcification subsequently, on an APG2-02-P coaguometer. In this research, we confirmed the effectiveness of this technique for the comparative analysis of hemostatic implants. In addition, the results of the research showed that all the samples used by us significantly reduce the coagulation time in the experiment compared with the control.

scholarly journals Marketing research of the domestic pharmaceutical market of antihemorrhagict

2016 ◽  
Vol 2 (3) ◽  
pp. 65-74
Author(s):  
S. A. Kutsenko ◽  
V. V. Malyi ◽  
А. B. Olkhovska ◽  
Ju. S. Masliy
Keyword(s):  
Marketing Research ◽  
Pharmaceutical Market

scholarly journals Marketing analysis of the market segment of drugs – derivatives of 9,10-anthraquinone in Ukraine

2021 ◽  
Vol 4 (1) ◽  
pp. 116-125
Author(s):  
M. V. Stasevych ◽  
◽  
V. I. Zvarych ◽  
Keyword(s):  
Pharmaceutical Company ◽  
Raw Materials ◽  
Dosage Forms ◽  
Pharmaceutical Market ◽  
Market Segment ◽  
Pharmaceutical Factory ◽  
Marketing Analysis ◽  
Derivatives Of

A marketing analysis of the pharmaceutical market for drugs - derivatives of 9,10-anthraquinone was carried out. It is shown that in the Ukrainian market, the vast majority of the assortment of these drugs is formed by foreign-made drugs, the leaders of which are the manufacturing countries Austria, Italy, Germany and India. It has been determi ned that the majority of anthraquinone drugs are represented by agents for the treatment of diseases of various types of cancer and strengthening of the intestinal reticulum. It has been established that “Sinbias Pharma” LLC is engaged in the production of four anticancer substances in Ukraine. For preparations based on anthraquinone-containing medicinal herbal raw materials, domestic manufacturers are PJSC “Liktravy” and PJSC Pharmaceutical Factory “Viola”, and the producers of senna glycosides are JSC “Lubnypharm”, “Ternopharm” LLC and Pharmaceutical company “Zdorovye”. Injection solutions, lyophilisates, tablets and hard capsules are the main dosage forms of drugs – derivatives of 9,10-anthraquinone.

scholarly journals Assortment research of analgesic drugs for chronic pain treatment on pharmaceutical market of Ukraine

2020 ◽  
pp. 16-28
Author(s):  
I. V. Zupanets ◽  
O. A. Ruban ◽  
O. M. Ievtushenko ◽  
Т. E. Kolisnyk
Keyword(s):  
Chronic Pain ◽  
Pain Therapy ◽  
Pain Treatment ◽  
Life Quality ◽  
Marketing Research ◽  
Hepatoprotective Activity ◽  
Dosage Forms ◽  
Pharmaceutical Market ◽  
Narcotic Analgesics ◽  
Chronic Pain Treatment

Chronic pain reduces patients’ life quality, affects their social and productive function in the state for a long period of time, or even for a whole lifetime. For the chronic pain treatment analgesic medications of symptomatic action are prescribed. According to international guidelines, paracetamol is one of the first line drugs. Aim – сonducting an assortment analysis of pharmaceutical medicines of Ukraine that can be used for the treatment of сhronic pain. Search for combined analgesics with hepatoprotective activity for the treatment of сhronic pain. Information sources: State Register of Medicines of Ukraine, Compendium web site. The analysis was conducted using content analysis and marketing research. Data processing and graphical analysis were performed in MS Excel software. During the marketing analysis of the registered in Ukraine medicines that can be used for mild and moderate сhronic pain treatment, the international non-proprietary names, listed in the national protocol of Ukraine, were selected. According to the ATC classification, these are groups N02B (non-narcotic analgesics) and M01A (non-steroidal anti-inflammatory and antirheumatic agents). N02B group has 245 registered drugs, 53.06% of which are produced domestically. Group M01A consists of 392 trade names that can be used for сhronic pain therapy. The ratio of Ukrainian manufacturers is only 39.80%, while foreign ones – 60.20%. For the treatment of сhronic pain tablet or capsule dosage forms are used. The market of analgesic products of Ukraine that can be used for сhronic pain therapy has been analyzed. It is established that the pharmaceutical market of Ukraine is import-dependent and promising for domestic enterprises. In Ukraine there are no drugs with paracetamol in combination with hepatoprotective ingredients and preparations directed exceptionally to сhronic pain treatment. In addition, there are practically no drugs of this direction in modern dosage forms (orally disintegrating tablets, soluble tablets, modified-release tablets, etc.) that improve patient compliance. All this is the basis for increasing the assortment of products in modern dosage forms.

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