scholarly journals Investigation of the Relationship between IgG and Telomerase In Simental Cattle In Different Age Groups

2021 ◽  
Author(s):  
Serkan ÇETİNER ◽  
Şima ŞAHİNDURAN
Keyword(s):  
Age Groups ◽  
The Relationship

TO STUDY THE DYNAMICS OF IMMUNITY IN BLACK-AND-WHITE COWS DEPENDING ON AGE

2020 ◽  
pp. 49-52
Author(s):  
М.В. ДОВЫДЕНКОВА
Keyword(s):  
Bactericidal Activity ◽  
Phagocytic Activity ◽  
Physiological State ◽  
Age Groups ◽  
Statistical Processing ◽  
Natural Resistance ◽  
Black And White ◽  
Feeding Methods ◽  
High Degree ◽  
The Relationship

Проведена статистическая обработка сформированной базы данных показателей неспецифической резистентности MS «Excel» с целью изучения динамики иммунитета по параметрам бактерицидной, лизоцимной и фагоцитарной активности у крупного рогатого скота черно-пестрой породы разных возрастов. Было установлено, что средние значения показателей лизоцимной и бактерицидной активности у телят в 6 мес были ниже (47,89% и 49,09%, соответственно), чем у животных в 3—4 года (53,75% и 52,81%). Выведено уравнение регрессии, описывающее взаимосвязь между средними показателями фагоцитарной активности и возрастом при высокой степени достоверности (R2=0,90). Изменения лизоцимной и бактерицидной активности в зависимости от возраста были недостоверными (R2=0,58 и R2=0,49, соответственно). Установлена высокая корреляция между бактерицидной и лизоцимной активностью. Отмечена динамика изменения неспецифического иммунитета у коров различных возрастных групп. Создание баз данных и постоянный мониторинг основных показателей естественной резистентности в зависимости от различных факторов (породы, возраста, стадий лактации, кормления, способов содержания), которые влияют на данные показатели, необходимо для оценки физиологического состояния организма животных и их устойчивости к болезням. Statistical processing of the generated MS "Excel" on indicators of non-specific resistance database was carried out with the aim of studying the dynamics of the development of immunity in terms of bactericidal, lysozyme and phagocytic activity in black-and-white cattle of different ages. It was found that the average values of indicators of lysozyme and bactericidal activity in calves at 6 months were lower (47.89% and 49.09%, respectively) than in animals at the age of 3—4 years (53.75% and 52.81%). The equation of regression was derived, it describes the relationship between the average indicators of phagocytic activity and the age with a high degree of reliability (R2=0.90). The changes in lysozyme and bactericidal activity depending on age were dubious (R2=0.58 and R2=0.49, respectively). The high correlation between bactericidal and lysozyme activity was established. It was noticed that the cows of different age groups experienced the dynamics of changes in nonspecific immunity. The creation of databases and constant monitoring of the main indicators of natural resistance, depending on various factors (breed, age, stages of lactation, feeding, methods of keeping) that affect these indicators, is necessary for assessing the physiological state of the animals’ body of and their resistance to diseases.

Association between Social Media Use for Health Purpose and Depressive Symptoms: A Cross-Sectional Survey (Preprint)

2020 ◽  
Author(s):  
Hee Yun Lee ◽  
Yan Luo ◽  
Cho Rong Won ◽  
Jiyoung Lee ◽  
Jeongwon Baik
Keyword(s):  
Social Media ◽  
Depressive Symptoms ◽  
Social Networking Sites ◽  
Inverse Relationship ◽  
Age Groups ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Use Of Social Media ◽  
The Relationship ◽  
Health Purpose

BACKGROUND The use of social media or social networking sites (SNS) is increasing across all age groups, and one of the primary motives of using SNS is to seek health-related information. Although previous research examining the effect of SNS use on depression exist, studies regarding the effect of SNS use for health purpose on depression is limited. OBJECTIVE Our study aims to explore the relationship between SNS use for health purpose and depression across the four age groups (18-34 years old, 35-49 years old, 50-64 years old, and above 65 years old). METHODS A sample of 6,789 adults aged 18 and older was extracted from a 2017 and 2018 Health Information National Trends Survey (HINTS). Univariate and bivariate analyses to examine the association between each variable and four age groups were conducted. Multiple linear regression analyses to predict depression level among participants with use of SNS for health purpose were conducted. RESULTS SNS use for health purpose and depression were positively associated for three age groups but not for those 65 years or older (=0.13, P<0.05; =0.08, P<0.05; =0.09, P<0.05). Income and self-reported health status indicated an inverse relationship for all age groups. The relationship with marital status differed based on age group with 18 and 34 years old showing an inverse relationship (=-0.13, P<0.01) while 65 years or older showing a positive relationship (=0.06, P<0.05). Gender was positively associated among those in the 35-49 years old (=0.09, P<0.05) and 65 years or older (=0.07, P<0.05). Being Non-Hispanic White was positively associated with depression among 50-64 years old (=0.07, P<0.001) and 65 years or older (=0.08, P<0.05). CONCLUSIONS Age-tailored education on determining accurate and reliable information shared via SNS is needed to reduce depressive symptoms.

Prevalence of imaginary companions among Chinese children aged 4 to 6 years

2020 ◽  
Vol 48 (3) ◽  
pp. 1-11
Author(s):  
Qiyi Lin ◽  
Nan Zhou ◽  
Hong Fu
Keyword(s):  
Age Groups ◽  
Income Group ◽  
Internal Variables ◽  
Annual Income ◽  
Imaginary Companions ◽  
Socioeconomic Environment ◽  
Imaginary Play ◽  
Relationship Qualities ◽  
Different Dimensions ◽  
The Relationship

We investigated the prevalence of Chinese children's imaginary companions (ICs) and the internal variables of IC types (personified object or invisible friend) and child–IC relationship qualities (egalitarian or hierarchical child–IC relationship). Participants were 266 children aged 4 to 6 years. Only in the 5-year-old group was the proportion of children with ICs significantly higher among girls than among boys, implying that the relationship between gender and IC was not consistent across age groups. Children from families in the highest annual income group engaged in more IC play than did children from families in the lowest annual income group, indicating a relationship between family socioeconomic environment and children's imaginary play. IC types were not associated with child–IC relationship qualities in any of the age groups, implying that these qualities may represent different dimensions of IC play as early as 4 years old.

scholarly journals Validation of a French Version of the Career Decision-Making Difficulties Questionnaire: Relationships With Self-Esteem and Self-Efficacy

2021 ◽  
pp. 089484532110099
Author(s):  
Jérôme Rossier ◽  
Shékina Rochat ◽  
Laurent Sovet ◽  
Jean-Luc Bernaud
Keyword(s):  
Decision Making ◽  
Career Counseling ◽  
Self Efficacy ◽  
Age Groups ◽  
Career Decision ◽  
Self Esteem ◽  
Career Decision Making ◽  
Student Sample ◽  
French Version ◽  
The Relationship

The aim of this study was to validate the French version of the Career Decision-Making Difficulties Questionnaire (CDDQ) and to assess its measurement invariance across gender, age groups, countries, and student versus career counseling samples. We also examined the sensitivity of this instrument to discriminate a career counseling population from a general student sample. Third, we studied the relationship between career decision-making difficulties, career decision-making self-efficacy, and self-esteem in a sample of 1,748 French and French-speaking Swiss participants. A confirmatory factor analysis confirmed the overall hierarchical structure of the CDDQ. Multigroup analysis indicated that the level of invariance across groups almost always reached configural, metric, and scalar invariance. Differences between countries were very small, whereas differences between the general population and career counseling subsamples were much larger. Both self-esteem and self-efficacy significantly predicted career decision-making difficulties. Moreover, as expected, self-efficacy partially mediated the relationship between self-esteem and career decision-making difficulties.

121 Behavioral Attention Relationships Vary Between Demographic Groups Across Sleep Loss and Recovery

SLEEP ◽  
2021 ◽  
Vol 44 (Supplement_2) ◽  
pp. A49-A50
Author(s):  
Caroline Antler ◽  
Erika Yamazaki ◽  
Tess Brieva ◽  
Courtney Casale ◽  
Namni Goel
Keyword(s):  
Sleep Deprivation ◽  
Repeated Measures ◽  
Age Groups ◽  
Response Speed ◽  
Sleep Loss ◽  
Demographic Groups ◽  
Time In Bed ◽  
Median Split ◽  
The Relationship ◽  
High Bmi

Abstract Introduction The Psychomotor Vigilance Test (PVT) is a behavioral attention measure widely used to describe sleep loss deficits. Although there are reported differences in PVT performance for various demographic groups, no study has examined the relationship between measures on the 10-minute PVT (PVT10) and the 3-minute PVT (PVT3) within sex, age, and body mass index (BMI) groups throughout a highly controlled sleep deprivation study. Methods Forty-one healthy adults (mean±SD ages, 33.9±8.9y) participated in a 13-night experiment [2 baseline nights (10h-12h time in bed, TIB) followed by 5 sleep restriction (SR1-5) nights (4h TIB), 4 recovery nights (R1-R4; 12h TIB), and 36h total sleep deprivation (TSD)]. A neurobehavioral test battery, including the PVT10 and PVT3 was completed every 2h during wakefulness. Repeated measures correlation (rmcorr) compared PVT10 and PVT3 lapses (reaction time [RT] &gt;355ms [PVT3] and &gt;500ms [PVT10]) and response speed (1/RT) by examining correlations by day (e.g., baseline day 2) and time point (e.g., 1000h-2000h) within sex groups (18 females), within age groups defined by a median split (median=32, range=21-49y), and within BMI groups defined by a median split (median=25, range=17-31). Results PVT10 and PVT3 1/RT was significantly correlated at all study days and time points excluding at baseline for the younger group and at R2 for the higher BMI group. PVT10 and PVT3 lapses showed overall lower correlations across the study relative to 1/RT. Lapses were not significantly correlated at baseline for any group, for males across recovery (R1-R4), for the high BMI group at R2-R4, for the older group at R2-R3, or for the younger group at SR5 or R3. Conclusion Differentiating participants based on age, sex, or BMI revealed important variation in the relationship between PVT10 and PVT3 measures across the study. Surprisingly, lapses were not significantly correlated at baseline for any demographic group or across recovery for males or the high BMI or older group. Thus, PVT10 and PVT3 lapses may be less comparable in certain populations when well-rested. These findings add to a growing literature suggesting demographic factors may be important factors to consider when evaluating the effects of sleep loss. Support (if any) ONR Award N00014-11-1-0361;NIH UL1TR000003;NASA NNX14AN49G and 80NSSC20K0243; NIHR01DK117488

scholarly journals Antiphospholipid Antibodies in Sickle Cell Disease: A Systematic Review and Exploratory Meta-Analysis

2021 ◽  
Vol 27 ◽  
pp. 107602962110029
Author(s):  
Mira Merashli ◽  
Alessia Arcaro ◽  
Maria Graf ◽  
Matilde Caruso ◽  
Paul R. J. Ames ◽  
...  
Keyword(s):  
Sickle Cell Disease ◽  
Sickle Cell ◽  
Antiphospholipid Antibodies ◽  
Meta Analysis ◽  
Age Groups ◽  
Anticardiolipin Antibodies ◽  
Cell Disease ◽  
Pooled Prevalence ◽  
The Relationship

The relationship between antiphospholipid antibodies (aPL) and sickle cell disease (SCD) has never been systematically addressed. Our aim was to evaluate potential links between SCD and aPL in all age groups. EMBASE/PubMed was screened from inception to May 2020 and Peto odds ratios for rare events were calculated. The pooled prevalence (PP) of IgG anticardiolipin antibodies (aCL) was higher in individuals with SCD than in controls (27.9% vs 8.7%, P < 0.0001), that of IgM aCL was similar in the two groups (2.9% vs 2.7%); only individuals with SCD were positive for lupus anticoagulant (LA) (7.7% vs 0%, P < 0.0001). The PP of leg ulcers was similar between aPL positive and negative individuals (44% vs 53%) and between patients in acute crisis and stable patients (5.6% vs 7.3%). Reporting of aPL as a binary outcome and not as a titer precluded further interpretation. The results indicate that a prospective case-control study with serial measurements of a panel of aPL in SCD patients might be warranted, in order to understand further the possible pathogenic role of aPL in SCD.

scholarly journals Differential Influence of Age on the Relationship between Genetic Mismatch and A(H1N1)pdm09 Vaccine Effectiveness

Viruses ◽  
2021 ◽  
Vol 13 (4) ◽  
pp. 619
Author(s):  
Lirong Cao ◽  
Shi Zhao ◽  
Jingzhi Lou ◽  
Hong Zheng ◽  
Renee W. Y. Chan ◽  
...  
Keyword(s):  
Age Groups ◽  
The Elderly ◽  
Vaccine Effectiveness ◽  
Amino Acid Mutation ◽  
Epidemic Season ◽  
Vaccine Component ◽  
Linear Relationships ◽  
The Difference ◽  
Middle Aged Adults ◽  
The Relationship

Assessment of influenza vaccine effectiveness (VE) and identification of relevant influencing factors are the current priorities for optimizing vaccines to reduce the impacts of influenza. To date, how the difference between epidemic strains and vaccine strains at genetic scale affects age-specific vaccine performance remains ambiguous. This study investigated the association between genetic mismatch on hemagglutinin and neuraminidase genes and A(H1N1)pdm09 VE in different age groups with a novel computational approach. We found significant linear relationships between VE and genetic mismatch in children, young adults, and middle-aged adults. In the children’s group, each 3-key amino acid mutation was associated with an average of 10% decrease in vaccine effectiveness in a given epidemic season, and genetic mismatch exerted no influence on VE for the elderly group. We demonstrated that present vaccines were most effective for children, while protection for the elderly was reduced and indifferent to vaccine component updates. Modeling such relationships is practical to inform timely evaluation of VE in different groups of populations during mass vaccination and may inform age-specific vaccination regimens.

scholarly journals Factors Contributing to the Relationship between Driving Mileage and Crash Frequency of Older Drivers

2019 ◽  
Vol 11 (23) ◽  
pp. 6643 ◽  
Author(s):  
Lee ◽  
Guldmann ◽  
Choi
Keyword(s):  
Negative Binomial ◽  
Age Groups ◽  
Urban Environments ◽  
Vehicle Miles Traveled ◽  
Crash Frequency ◽  
Rural Environments ◽  
Lower Likelihood ◽  
Conditional Autoregressive ◽  
The Relationship ◽  
Binomial Models

As a characteristic of senior drivers aged 65 +, the low-mileage bias has been reported in previous studies. While it is thought to be a well-known phenomenon caused by aging, the characteristics of urban environments create more opportunities for crashes. This calls for investigating the low-mileage bias and scrutinizing whether it has the same impact on other age groups, such as young and middle-aged drivers. We use a crash database from the Ohio Department of Public Safety from 2006 to 2011 and adopt a macro approach using Negative Binomial models and Conditional Autoregressive (CAR) models to deal with a spatial autocorrelation issue. Aside from the low-mileage bias issue, we examine the association between the number of crashes and the built environment and socio-economic and demographic factors. We confirm that the number of crashes is associated with vehicle miles traveled, which suggests that more accumulated driving miles result in a lower likelihood of being involved in a crash. This implies that drivers in the low mileage group are involved in crashes more often, regardless of the driver’s age. The results also confirm that more complex urban environments have a higher number of crashes than rural environments.

Social Well-Being of the Population of Russia During the Pandemic (Based on Sample Survey Data)

2021 ◽  
Vol 28 (4) ◽  
pp. 67-79
Author(s):  
L. A. Davletshina ◽  
N. A. Sadovnikova ◽  
A. V. Bezrukov ◽  
O. G. Lebedinskaya
Keyword(s):  
Health Status ◽  
Population Health ◽  
Age Distribution ◽  
Age Groups ◽  
Rank Correlation ◽  
Well Being ◽  
Russian Population ◽  
Sample Survey ◽  
The Social ◽  
The Relationship

The article present results of the authors’ study of the social well-being of the Russian population – an assessment of the population’s health and attitudes towards a healthy lifestyle amid viral pandemic, based on materials of the Rosstat sample surveys of 2019 and 2020 and data from the All-Russian survey conducted by the Russian Public Opinion Research Center (VCIOM) on 27 September 2020. The authors described the transformation of living conditions in the light of the complex epidemiological situation and the increase in coronavirus cases among the population. Changes in the health status of the Russian population were analyzed by individual age groups.The article assesses the strength of the relationship between the social well-being of the population by selected socio-demographic groups and the period of self-isolation, quarantine, or other restrictions imposed during the coronavirus pandemic in 2020. To solve this problem, demographic and socio-economic characteristics of respondents are presented, the distribution of responses according to the survey results is estimated, and the most signifcant factor characteristics are selected. Respondent replies were grouped according to the selected questions, including in the territorial context (by federal districts). To determine the strength of the relationship between the respondents' answers to the question and their gender or age distribution, the coefcients of mutual conjugacy and rank correlation coefcients were calculated and analyzed.Analysis of the changes in the social well-being of population for 2019–2020 and the assessment of the strength of the relationship between the discussed indicators (gender, wealth, territory of residence) revealed the parameters that form the differences. After comparing the health status of the Russian population as a whole and by age groups in 2019 and 2020 based on data of sample survey on population health status, the following points were identifed. With the expected assessment of the population health status in the age distribution (deterioration in the older ages and better health in the younger ones), it also remains unchanged that more than half of the respondents characterize their health status as «very good» and «good». Noteworthy is the fact that the assessment of the health status of the Russian population has improved during the year. It is evidenced from changes in the structure of respondent replies, even though population health status survey of 2020 was conducted in the middle of lockdown amid the continuing negative trends in coronavirus morbidity and mortality.

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