Incidence of depression and its influencing factors in 387 patients with asthma from Xinjiang, China

2020 ◽  
Vol 41 (2) ◽  
pp. e45-e53 ◽  
Author(s):  
Dilinuer Wufuer ◽  
Haidiya Aierken ◽  
Yan Fang ◽  
Mihereguli Simayi ◽  
Kelibiena Tuerxun ◽  
...  
Keyword(s):  
Risk Factors ◽  
Regression Analysis ◽  
Depression Scale ◽  
High Morbidity ◽  
Hamilton Depression Scale ◽  
Multiple Factors ◽  
Asthma Symptoms ◽  
Depression Status ◽  
Treatment Of Depression ◽  
Quality Life

Background: Our study aimed to investigate the incidence of depression in 387 patients with asthma. Methods: The Zung self-rating depression scale and the Hamilton depression scale were used to evaluate the depression status in patients with asthma. Results: Results of logistic regression analysis indicated that, severity of asthma symptoms, taking medicine, frequency of asthma onset, and lack of education were the major risk factors for depression in patients with asthma. Conclusion: Depression is a complication with high morbidity in patients with asthma. It largely affects disease control of asthma and the quality life in patients. Multiple factors are relevant for depression in the patient with asthma. This study provided a comprehensive horizon for clinical management and treatment of depression in patients with asthma.

Association among Items from the Self-Report Version of the Hamilton Depression Scale (Carroll Rating Scale) and Respondents' Sex

2007 ◽  
Vol 101 (1) ◽  
pp. 291-301 ◽  
Author(s):  
Ana Luiza Camozzato ◽  
Maria Paz Hidalgo ◽  
Sônia Souza ◽  
Márcia L. F. Chaves
Keyword(s):  
Sex Differences ◽  
Regression Analysis ◽  
General Population ◽  
Rating Scale ◽  
Depression Scale ◽  
The Self ◽  
Self Report ◽  
Sex Bias ◽  
Hamilton Depression Scale ◽  
Nonclinical Sample

The association among items of the self-reported version of the Hamilton Depression Scale (Carroll Rating Scale), answered according to a memory of a maximally disturbing event experienced, and respondents' sex was examined in a nonclinical sample of 320 college students, 164 women ( M age = 21.7 yr., SD = 3.6) and 156 men ( M age = 23.5 yr., SD = 5.8). An assessment of sex bias was also evaluated. Multiple regression analysis showed that statements regarding unhappiness, urge to cry, dizziness and faintness, and waking in the middle of the night were significantly associated with women. Removal of these items from the Carroll Rating Scale Total scores eliminated the sex differences in depression rates. Items that displayed significant sex bias were those regarding behavior and emotions commonly attributed to women within the general population.

scholarly journals Determination of the Prevalence of Postpartum Depression and Risk Factors Among Postpartum Patients at a Tertiary Government Urban Hospital Using the Edinburgh Postnatal Depression Scale-Filipino Translation (EPDS-F): A Cross-Sectional Study

2020 ◽  
Author(s):  
Maria Carmina Lorenzana Santiago ◽  
Maria Antonia Esteban Habana
Keyword(s):  
Risk Factors ◽  
Regression Analysis ◽  
Postpartum Depression ◽  
Postnatal Depression ◽  
Edinburgh Postnatal Depression Scale ◽  
Mode Of Delivery ◽  
Depression Scale ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional

Abstract Background Postpartum depression (PPD) occurs in 10-15% of deliveries worldwide. Unfortunately there is a dearth of local studies on its exact prevalence. Method This cross-sectional study aimed to determine the prevalence of and risk factors for PPD among postpartum patients at a tertiary government hospital using the Edinburgh Postnatal Depression Scale-Filipino Translation (EPDS-F), a 10-point questionnaire translated into Filipino and previously validated. Four hundred patients within 8 weeks postpartum were recruited and their EPDS-F scores and sociodemographic, medical and personal history, and delivery and perinatal outcome data were obtained. Results The overall prevalence of PPD was 14.5%, which is within the known worldwide prevalence. Among those that had family incomes below PhP10,000, the proportion that had high EPDS-F scores was 68.8%, while those that had low EPDS-F scores was 48.8% (significant at p=0.001). Among those that finished below tertiary education, the proportion that had high EPDS-F scores was 81%, while those that had low EPDS-F scores was 59.9% (significant at p=0.002). Among those who delivered vaginally, 62.1% had high EPDS-F scores vs 44.2% low EPDS-F (p=0.03). Of those that had epidural anesthesia (106 or 26.5%), 44.8% had high EPDS scores and 26.0% had low EPDS-F scores (p=0.04). Regression analysis showed that having an abdominal delivery is correlated with a lower EPDS-F score by 0.87% by logistic regression and 0.46 % by probit regression. Having a higher educational attainment and monthly income are associated with a lower EPDS-F score by regression analysis. Conclusions The prevalence may be skewed because a tertiary government institution caters to delicate pregnancies and those in low socioeconomic brackets. It may be worthwhile to compare responses from a public versus a private institution, also urban versus rural areas. It would be interesting also to evaluate the mode of delivery variable and how exactly it correlates with the development of postpartum depression.

scholarly journals Correlation of Catecholamine Content and Clinical Influencing Factors in Depression among Psoriasis Patients: A Case-Control Study

2020 ◽  
Author(s):  
Hui-Ling Shu ◽  
Jing Fang ◽  
Deng-Mei Xia ◽  
Zheng-Qun Wang ◽  
Wen-Yao Mi ◽  
...  
Keyword(s):  
Risk Factors ◽  
Influencing Factors ◽  
Psoriasis Vulgaris ◽  
Depression Scale ◽  
Control Group ◽  
Hamilton Depression Scale ◽  
Dermatology Department ◽  
Dopamine Content ◽  
Significant Difference ◽  
The Mean

Abstract Backgroud: This study sought to investigate the clinical influencing factors of patients with psoriasis vulgaris complicated with depression, and to analyze whether the content of monoamine neurotransmitters in plasma was correlated with depression incidence among psoriasis patients. Methods Ninety patients aged 18-60 years with psoriasis vulgaris referred to the dermatology department and 40 healthy volunteers aged 18-60 years referred to the physical examination center of the Affiliated Hospital of Southwest Medical University were included. Questionnaires were administered in both groups to obtain basic patient information, Hamilton Depression Scale(HAMD), and Athens Insomnia Scale(AIS) scores. The questionnaire only for patients with psoriasis vulgaris included the course of disease, Psoriasis Area and Severity Index (PASI), and Dermatology Life Quality Index (DLQI). The catecholamine in plasma from the two groups was analyzed by radioimmunoassay. The data were analyzed by SPSS statistical software. Results: The mean HAMD (P=0.034) and mean AIS scores (P=0.001) of the psoriasis patients were higher than those of the control group, while the mean content of dopamine (P=0.004) and adrenaline in the plasma (P=0.007) of the psoriasis group were lower than those of the control group. Dopamine content in the plasma was lower (comparing psoriasis patients without depression and the control group: P<0.001), and was negatively correlated with HAMD, (P<0.05), AIS (P<0.05), and PASI scores (P<0.05) in the psoriasis patients with depression. There was no significant difference in the epinephrine and norepinephrine contents in all groups. PASI scores were positively correlated with HAMD scores in patients with psoriasis vulgaris, and the mean dopamine content in the patients with depression (P=0.001) was significantly lower than in those without depression. The low dopamine content and high PASI and DLQI scores were the risk factors for depression among the patient population. Conclusion: Psoriasis patients have a significantly higher risk of depression than healthy people, and higher PASI scores were linked to a higher incidence of depression. The dopamine levels of patients were influenced by both psoriasis and depression. The risk factors for depression in psoriasis patients are low dopamine levels in the plasma, severe skin lesions, and lower quality of life.

Influence of depression on the quality of life after stroke

2017 ◽  
Vol 41 (S1) ◽  
pp. S475-S475
Author(s):  
E. Kostadinova ◽  
A. Anita
Keyword(s):  
Quality Of Life ◽  
Risk Factors ◽  
Negative Impact ◽  
Depression Scale ◽  
Hamilton Depression Scale ◽  
Stroke Patients ◽  
Sf 36 ◽  
Degree Of Disability ◽  
Associated Risk Factors

AimApproximately 30–60% of the stroke survivors suffers from depression. This, together with the physical changes after stroke may lead to a decline in their quality of life (QOL). The aim of this paper was to analyse the incidence of post-stroke depression, associated risk factors and its influence on the QOL.Material and methodsWe carried out a prospective study on stroke patients during a period of 6months. We excluded patients with dysphasia and aphasia. For each patient, we collected socio-demographic characteristics as well as clinical and therapeutic data. We used the Hamilton Depression Scale to screen for anxiety and depression, the SF-36 scale to assess the quality of life and modified Rankin scale (mRS) to measure the degree of disability.ResultsWe included 155 men and 143 women with stroke, with mean age of 58.15 years. Out of 298 analysed patients, depression was present in 147 (49.3%). Associated risk factors were hypertension, female gender and severity of stroke (P < 0.05). The mean score of the SF-36 was 52.18. Impaired QOL was found in 221 (74.1%) and mRS > 3 was found in 169 (57.1%) of the patients. Impaired mental component of QOL significantly correlated with the presence of depression (P < 0.05) and anxiety (P < 0.05). The severe degree of disability had a significant negative impact on all areas of QOL.ConclusionImportant effect after stroke is occurrence of depression which affects the QOL and functional outcome. All stroke patients should be evaluated for depression through regular interviews with them and their families or caregivers. Adequate antidepressant treatment should be given, in order to improve the QOL and physical rehabilitation.Disclosure of interestThe authors have not supplied their declaration of competing interest.

The treatment of depression in general practice: a comparison of L-tryptophan, amitriptyline, and a combination of L-tryptophan and amitriptyline with placebo

1982 ◽  
Vol 12 (4) ◽  
pp. 741-751 ◽  
Author(s):  
Joan Thomson ◽  
H. Rankin ◽  
G. W. Ashcroft ◽  
Celia M. Yates ◽  
Judith K. McQueen ◽  
...  
Keyword(s):  
Depression Scale ◽  
Double Blind Study ◽  
Global Rating ◽  
Hamilton Depression Scale ◽  
Double Blind ◽  
Treatment Groups ◽  
Plasma Tryptophan ◽  
Treatment Of Depression ◽  
Biochemical Profiles ◽  
The Difference

SynopsisOne hundred and fifteen patients from 5 general practices participated in a 12-week, double-blind study comparing L-tryptophan, amitriptyline, L-tryptophan–amitriptyline combination and placebo in the treatment of depression. Analysis of total score on the Hamilton Depression Scale and a global rating of depression showed that all 3 active treatments were more effective than placebo. Significantly more patients were withdrawn as treatment failures in the placebo group compared with the active treatment groups. Side-effects necessitated withdrawal of more patients from the amitriptyline group than from the other active tratment groups, but this difference was not significant. Plasma amitriptyline and nortriptyline levels were similar in the difference was not significant. Plasma amitriptyline and nortriptyline and biochemical profiles did not alter significantly in any group, but mean heart rate was significantly increased in patients receiving amitriptyline. There was no change in free or total plasma tryptophan concentration with treatment or on remission of symptoms.

A Controlled Study of Repetitive Transcranial Magnetic Stimulation as a Treatment of Depression in the Elderly

2001 ◽  
Vol 13 (2) ◽  
pp. 225-231 ◽  
Author(s):  
Facundo Manes ◽  
Ricardo Jorge ◽  
Maria Morcuende ◽  
Toru Yamada ◽  
Sergio Paradiso ◽  
...  
Keyword(s):  
Transcranial Magnetic Stimulation ◽  
Treatment Response ◽  
Magnetic Stimulation ◽  
Repetitive Transcranial Magnetic Stimulation ◽  
Depression Scale ◽  
The Elderly ◽  
Controlled Study ◽  
Hamilton Depression Scale ◽  
Treatment Of Depression ◽  
Scale Scores

Rapid transcranial magnetic stimulation (rTMS) applied to the left dorsal lateral frontal cortex has been shown to produce antidepressant effects. Older depressed patients, however, in one study showed a lower response rate than younger patients. The current study examined treatment response in 20 depressed, treatment-refractory patients (mean age 60.7 ± 9.8 years) given five sessions of rTMS at 20 Hz for 2 seconds over 20 trains at 80% of motor threshold or identical placebo stimulation, after patients had been withdrawn from their antidepressants. There were no significant differences in Hamilton Depression Scale scores either before or after treatment at 7 days' follow-up. There were three responders to active treatment and three to sham treatment and responders had significantly greater frontal lobe volume than nonresponders (p=.03). These findings suggest that the stimulation parameters used in this study were probably insufficient to produce treatment response and that frontal atrophy may interfere with the effectiveness of rTMS.

scholarly journals Stunting Among Under 5-Year-Olds in Nepal: Trends and Risk Factors

2019 ◽  
Vol 24 (S1) ◽  
pp. 39-47 ◽  
Author(s):  
Shyam Sundar Budhathoki ◽  
Amit Bhandari ◽  
Rejina Gurung ◽  
Abhishek Gurung ◽  
Ashish KC
Keyword(s):  
Risk Factors ◽  
Logistic Regression ◽  
Regression Analysis ◽  
Nutritional Status ◽  
Logistic Regression Analysis ◽  
Health Surveys ◽  
Multiple Logistic Regression Analysis ◽  
Multiple Logistic Regression ◽  
Multiple Factors ◽  
Children Under 5

Abstract Introduction The nutritional status in the first 5 years of life has lifelong and inter-generational impacts on individual’s potential and development. This study described the trend of stunting and its risk factors in children under 5 years of age between 2001 and 2016 in Nepal. Methods The study used datasets from the 2001, 2006, 2011 and 2016 Nepal Demographic Health Surveys to describe the trend of stunting in under 5-year children. Multiple logistic regression analysis was carried out to assess the risk factors for stunting at the time of the four surveys. Results The nutritional status of under 5-year children improved between 2001 and 2016. Babies born into poorer families had a higher risk of stunting than those born into wealthier families (AOR 1.51, CI 95% 1.23–1.87). Families residing in hill districts had less risk of stunting than those in the Terai plains (AOR 0.75, CI 95% 0.61–0.94). Babies born to uneducated women had a higher risk of stunting than those born to educated women (AOR 1.57, CI 95% 1.28–1.92). Discussion Stunting among under-5-year children decreased in the years spanning 2001–2016. This study demonstrated multiple factors that can be addressed to decrease the risk of stunting, which has important implications for neurodevelopment later in life. We add literature on risk factors for stunting in under-5-year children.

A Mini Review of Traditional Chinese Medicine for the Treatment of Depression in China

2009 ◽  
Vol 37 (02) ◽  
pp. 207-213 ◽  
Author(s):  
Hui Zhao ◽  
Xia Wan ◽  
Jia-Xu Chen
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Depression Scale ◽  
Treated Group ◽  
Hamilton Depression Scale ◽  
Medical Database ◽  
China National Knowledge Infrastructure ◽  
Randomized Controlled Clinical Trials ◽  
Knowledge Infrastructure ◽  
Treatment Of Depression

To systematically evaluate the effectiveness of Chinese herbal medicine for treating depression in China, the electronic medical database from China National Knowledge Infrastructure (CNKI) was searched using Chinese and the date is set, from 1st January 1994 to 1st August 2008. The 18 studies that met the entry criteria along with 1,260 randomized patients were included in this review. All studies with words like "randomization" or "quasi-randomization" in their abstracts were included, whether they used blinding or not. The results showed that the Chinese medicine treated group did not decrease the scores of the self-rating depression scale (-1.02, 95% CI -2.16 ~ 0.12, p = 0.08) and the scores of the Hamilton depression scale (-0.45, 95% CI -0.98 ~ 0.08, p = 0.10). The results showed there is no evidence to support that traditional Chinese medicine for depression has improved, which may be due to the low quality in all the trials. Therefore, more qualified, randomized controlled clinical trials are warranted to assure its efficacy.

scholarly journals Remission in Depression and Associated Factors at Different Assessment Times in Primary Care in Chile

2018 ◽  
Vol 14 (1) ◽  
pp. 78-88 ◽  
Author(s):  
Veronica Vitriol ◽  
Alfredo Cancino ◽  
Carlos Serrano ◽  
Soledad Ballesteros ◽  
Soledad Potthoff
Keyword(s):  
Primary Care ◽  
Partner Violence ◽  
Life Experiences ◽  
Depression Scale ◽  
Observation Time ◽  
Hamilton Depression Scale ◽  
Psychiatric Comorbidities ◽  
Significance Level ◽  
Treatment Of Depression ◽  
One Year

Objective:To determine the factors associated with remission at 3, 6, 9 and 12 months among depressive adult patients in primary care [PHC] in Chile.Methods:This is a one-year naturalistic study that followed 297 patients admitted for treatment of depression in eight primary care clinics in Chile. Initially, patients were evaluated using: the International Mini-Neuropsychiatric Interview [MINI], a screening for Childhood Trauma Events [CTEs], the Life Experiences Survey and a partner violence scale. The Hamilton Depression Scale [HDRS] was used to follow the patients during the observation time. Associations between the factors studied and the primary outcome remission [HDRS ≤ 7] were assessed using a dichotomous logistic regression and a multivariate Poisson regression. The significance level was 0.05.Results:Remission [HDRS ≤ 7] ranged between 36.7% at 3 months and 53.9% at 12 months. Factors that predicted poor remission during the observation time were: CTEs [Wald X2= 4.88, Exp B=0.94, CI 0.90-0.92, p=0.27]; psychiatric comorbidities [Wald X2= 10.73, Exp B=0.90, CI 0.85-0.96, p=0.01]; suicidal tendencies [Wald X2= 4.66, Exp B=0.88, CI 0.79-0.98, p=0.03] and prior treatment for depression [Wald X2= 4.50, Exp B=0.81, CI 0.68-0.85, p=0.03]Discussion:Almost 50% of this sample failed remission in depression at 12 months. Psychiatric comorbidities and CTEs are factors that should be considered for a poor outcome in depressed Chilean patients. These factors need more recognition and a better approach in PHC.

Clomipramine HCL — A Double-Blind Study of a New Antidepressant Drug

1973 ◽  
Vol 18 (5) ◽  
pp. 403-408 ◽  
Author(s):  
D.J. Mcclure ◽  
G.L. Low ◽  
M. Gent
Keyword(s):  
Antidepressant Drug ◽  
Depression Scale ◽  
Blind Study ◽  
Double Blind Study ◽  
Hamilton Depression Scale ◽  
Double Blind ◽  
Treatment Groups ◽  
Treatment Of Depression ◽  
Before And After ◽  
Anxiety Index

A double-blind study was carried out comparing the antidepressant and anxiolytic properties of clomipramine HCL (a new antidepressant) and imipramine on a group of 24 subjects suffering from psychotic depression. The patients were divided into two groups of twelve by random sampling. Clinical assessments were made by two independent psychiatrists using the Hamilton Depression Scale and the Beck Depression Inventory, and also by a psychologist using the Welsh Anxiety Index of the MMPI and IPAT scales. The assessments were carried out one day prior to treatment and on the 5th, 10th, 15th, 22nd and 44th day after treatment commenced. Clomipramine HCL was found to be as effective as imipramine in the treatment of depression, and it also showed similar anxiolytic properties. There were no significant changes in the laboratory tests carried out before and after the treatment program was completed in both treatment groups.

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