scholarly journals Perceptions of mothers with children affected by major congenital malformations: the need to develop a system of appropriate care. Qualitative study of focus groups

1969 ◽  
Vol 40 (1) ◽  
pp. 85-94
Author(s):  
Fernando Suárez Obando ◽  
Adriana Ordóñez ◽  
Marisol Macheta
Keyword(s):  
Focus Groups ◽  
Health System ◽  
Congenital Malformations ◽  
Genetic Factors ◽  
Descriptive Study ◽  
Mortality And Morbidity ◽  
Appropriate Care ◽  
Causes Of Mortality ◽  
Major Congenital Malformations ◽  
Epidemiological Profile

Introduction: The diseases that are partly or wholly determined by genetic factors, gradually assume a ratio of greater importance in the epidemiological profile of the child population, becoming one of the leading causes of mortality and morbidity. The perception of mothers of children affected by major congenital malformations has not been studied before in relation to the health system in Colombia. Objectives: To know the mother’s perceptions of children with congenital malformations, on the etiology of the disease for their children, medical care received and the potential consequences of the malformation. Methods: Qualitative exploratory descriptive study of focus groups with mothers of children suffering from major congenital malformations. Results: Mothers identified the problems of child care in relation to the health system, treatment ambivalent and prejudice of health personnel and the need for clear answers on the future of children, as well as the need for reforms in the health care of people affected.

scholarly journals Prevalence and associated risk factors of prehypertension and hypertension among army personnel

2018 ◽  
Vol 18 (17) ◽  
pp. 113-120
Author(s):  
Sapana Gurung ◽  
Padma Rai
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Descriptive Study ◽  
Common Disease ◽  
Cross Sectional ◽  
Mortality And Morbidity ◽  
The World ◽  
Causes Of Mortality ◽  
Associated Risk Factors ◽  
Army Personnel

Hypertension (HTN) is most likely a common disease in the world. In every 3 adult ages over 20 years have this disease. As a consequence, Non-communicable diseases (NCDs), such as hypertension and other cardiovascular diseases are becoming increasingly important as causes of mortality and morbidity in all developing countries. The aim of this study is to determine the prevalence of pre-hypertension and hypertension among the Army personnel in Nepal. This was a cross-sectional descriptive study of 315 respondents, who met eligible criteria. All respondents were enumerated by census method using self-interviewing questionnaire focusing measurement of the blood pressure, weight and height along with the demographic and other socio-economic as well as cultural characteristics. The study shows that overwhelming respondents (77.5%) are normal. And about 13 percent respondents are seemed to be in the pre-hypertension, followed by stage I HTN (6%) and stage II HTN (3.5%). It also shows that there is a significant association between prevalence of hypertension and body mass index of the respondents.

Chitosan-Based Hydrogel Nanoparticles for Cancer Therapy

2017 ◽  
Vol 7 (04) ◽  
Author(s):  
Azadi A. ◽  
Khazaei M. ◽  
Ashrafi H.
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Recent Decade ◽  
Reticuloendothelial System ◽  
Malignant Neoplasms ◽  
Mortality And Morbidity ◽  
Hydrogel Nanoparticles ◽  
Tissue Invasion ◽  
Causes Of Mortality ◽  
Nanoparticulate Systems

Cancer, an uncontrollable growth of cells, is among the leading causes of mortality and morbidity throughout the world. Malignant neoplasms are difficult to treat diseases because of their single in kind characteristics such as tissue invasion, metastasis, evading reticuloendothelial system (RES) and so forth. In recent decade polymeric nanoparticulate systems has gained special attention in drug delivery and targeting among all biocompatible nanoforms. Among these systems, chitosan-based hydrogel nanoparticles have been wildly utilized for drug delivery purposes. The usage of chitosan nanogels in cancer therapy significantly improved in recent years. The various cancers were the target of chitosan nanogels. Also, modification of other delivery systems with chitosan were much reported. The aim of this study is the review and update of the recent studies on chitosan nanogels applications in cancer therapy by focus on cancer based classification.

scholarly journals A75 IMPLEMENTING A CIRRHOSIS ORDER SET: A QUALITATIVE ANALYSIS OF PROVIDER-IDENTIFIED BARRIERS AND FACILITATORS

2021 ◽  
Vol 4 (Supplement_1) ◽  
pp. 41-42
Author(s):  
E Johnson ◽  
M Carbonneau ◽  
D Campbell-Scherer ◽  
P Tandon ◽  
A Hyde
Keyword(s):  
Focus Groups ◽  
Gastrointestinal Disease ◽  
Pragmatic Trial ◽  
Healthcare Providers ◽  
Structured Interview ◽  
Barriers And Facilitators ◽  
Care Utilization ◽  
Implementation Barriers ◽  
Mortality And Morbidity ◽  
Order Set

Abstract Background Cirrhosis is the leading cause of mortality and morbidity in individuals with gastrointestinal disease. Multiple care gaps exist for hospitalized patients with cirrhosis, resulting in high rates of re-hospitalization (e.g. 44% at 90 days in Alberta). The Cirrhosis Care Alberta (CCAB) is a 4-year multi-component pragmatic trial with an aim to reduce acute-care utilization by implementing an electronic order set and supporting education across eight hospital sites in Alberta. Aims As part of the pre-implementation evaluation, this qualitative study analyzed data from provider focus groups to identify barriers and facilitators to implementation. Methods We conducted focus groups at eight hospital sites with a total of 54 healthcare providers (3–12 per site). A semi-structured interview guide based upon constructs of the Consolidated Framework for Implementation Research (CFIR) and Normalization Process Theory (NPT) frameworks was used to guide the focus groups. Focus groups were recorded and transcribed verbatim. Data was analyzed thematically and inductively. Results Five major themes emerged across all eight sites: (i) understanding past implementation experiences, (ii) resource challenges, (iii) competing priorities among healthcare providers, (iv) system challenges, and (v) urban versus rural differences. Site-specific barriers included perceived lack of patient flow, time restraints, and concerns about the quality and quantity of past implementation interventions. Facilitators included passionate project champions, and an ample feedback process. Conclusions Focus groups were useful for identifying pre-implementation barriers and facilitators of an electronic orders set. Findings from this study are being refined to address the influence of COVID-19, and the data will be used to inform the intervention roll-out at each of the sites. Funding Agencies Alberta Innovates

scholarly journals Are Lipids Possible Markers of Suicide Behaviors?

2021 ◽  
Vol 10 (2) ◽  
pp. 333
Author(s):  
Agnieszka Kułak-Bejda ◽  
Grzegorz Bejda ◽  
Magdalena Lech ◽  
Napoleon Waszkiewicz
Keyword(s):  
Suicide Risk ◽  
Biological Marker ◽  
Low Density Lipoproteins ◽  
Low Density ◽  
Lipid Levels ◽  
Mortality And Morbidity ◽  
Additional Tool ◽  
Cholesterol Levels ◽  
Causes Of Mortality ◽  
Suicide Behaviors

Suicides and suicidal behaviors are very important causes of mortality and morbidity and have become a serious global problem. More than 800,000 people die from suicide every year. Previous researches have established that lipids play an important role in the pathogenesis of suicide. Moreover, lipid levels might be a biological marker of suicide. A lot of researchers have tried to identify biological markers that might be related to depressive disorder, bipolar disorder or schizophrenia and suicidal behavior. It was also important to consider the usefulness of an additional tool for prevention actions. Metabolic deregulation, particularly low total cholesterol and low-density lipoproteins-cholesterol levels may cause higher suicide risk in patients with these psychiatric disorders.

scholarly journals Congenital Malformations and Perinatal Deaths among the Children of Atomic Bomb Survivors: A Reappraisal

2021 ◽  
Author(s):  
Michiko Yamada ◽  
Kyoji Furukawa ◽  
Yoshimi Tatsukawa ◽  
Keiko Marumo ◽  
Sachiyo Funamoto ◽  
...  
Keyword(s):  
Pregnancy Outcomes ◽  
Congenital Malformations ◽  
Radiation Effects ◽  
Atomic Bomb ◽  
Perinatal Deaths ◽  
Neonatal Deaths ◽  
Atomic Bomb Survivors ◽  
Parental Exposure ◽  
Increased Risk ◽  
Major Congenital Malformations

Abstract From 1948 to 1954, the Atomic Bomb Casualty Commission conducted a study of pregnancy outcomes of children of atomic bomb survivors who had received radiation doses from zero to near-lethal levels. Past reports (1956, 1981, and 1990) on the cohort did not identify significant associations of radiation exposure with untoward pregnancy outcomes such as major congenital malformations, stillbirths, or neonatal deaths, individually or in aggregate. We have re-examined the risk of major congenital malformations and perinatal deaths in the children of the atomic bomb survivors (N=71,603) using fully reconstructed data to minimize the potential for bias, with refined estimates of the gonadal dose from the Dosimetry System 2002 and refined analytical methods for characterizing dose-response relationships. The analyses show that parental exposure is associated with increased risk for major congenital malformations and perinatal deaths, but the estimates are imprecise for direct radiation effects and most are not statistically significant. Nonetheless, the uniformly positive estimates for untoward pregnancy outcomes among children of both maternal and paternal survivors are useful for risk assessment purposes, although extending them to circumstances other than atomic bomb survivors comes with uncertainty as to the generalizability of the Hiroshima and Nagasaki populations.

scholarly journals A Fundamental, National, Medical Disaster Management Plan: An Education-Based Model

2009 ◽  
Vol 24 (6) ◽  
pp. 565-569 ◽  
Author(s):  
Ahmadreza Djalali ◽  
Vahid Hosseinijenab ◽  
Azadeh Hasani ◽  
Kianoush Shirmardi ◽  
Maaret Castrén ◽  
...  
Keyword(s):  
Health System ◽  
Disaster Management ◽  
Training Programs ◽  
Cost Benefit ◽  
Management Plan ◽  
Mortality And Morbidity ◽  
National Board ◽  
National Medical ◽  
Main Work ◽  
Training Team

AbstractDuring disasters, especially following earthquakes, health systems are expected to play an essential role in reducing mortality and morbidity. The most significant naturally occurring disaster in Iran is earthquakes; they have killed <180,000 people in the last 90 years. According to the current plan in 2007, the disaster management system of Iran is composed of three main work groups: (1) Prevention and risk management, (2) Education, and (3) Operation. This organizational separation has resulted in lack of necessary training programs for experts of specialized organizations, e.g., the Ministry of Health and Medical Education (MOHME).The National Board of MOHME arranged a training program in the field of medical disaster management. A qualified training team was chosen to conduct this program in each collaborating center, based on a predefined schedule. All collaborating centers were asked to recall 5–7 experts from each member university. Working in medical disaster management field for ≤2 years was an inclusion criterion. The training programs lasted three days, consisted of all relevant aspects of medical disaster management, and were conducted over a six-month period (November 2007–April 2008). Pretest and post-tests were used to examine the participants' knowledge regarding disaster management; the mean score on the pretest was 67.1 ±11.6 and 88.1 ±6.2, respectively. All participants were asked to hold the same training course for their organizations in order to enhance knowledge of related managers, stakeholders, and workers, and build capacity at the local and provincial levels. The next step was supposed to be developing a comprehensive medical disaster management plan for the entire country. Establishing nine disaster management regional collaborating centers in the health system of Iran has provided an appropriate base for related programs to be rapidly and easily accomplished throughout the country. This tree-shaped model is recommended as a cost-benefit and rapid approach for conducting training programs and developing a disaster management plan in the health system of a developing country.

CONGENITAL ATRESIA AND STENOSIS OF THE DUODENUM

PEDIATRICS ◽  
1969 ◽  
Vol 43 (1) ◽  
pp. 79-83
Author(s):  
Eric W. Fonkalsrud ◽  
Alfred A. deLorimier ◽  
Daniel M. Hays
Keyword(s):  
Congenital Malformations ◽  
Duodenal Obstruction ◽  
Duodenal Atresia ◽  
Operative Techniques ◽  
Congenital Atresia ◽  
Late Mortality ◽  
Congenital Duodenal Obstruction ◽  
American Academy Of Pediatrics ◽  
Associated Malformations ◽  
Major Congenital Malformations

A review is presented of 503 patients with congenital duodenal obstruction, compiled from 65 hospitals by the Surgical Section of the American Academy of Pediatrics. Four hundred eighty-seven patients underwent primary operative correction of the malformation with an overall early and late mortality rate of 36%. Complications from associated major congenital malformations were the leading cause of death. Many of these anomalies were potentially correctable had they been recognized and early treatment instituted. More than half of the infants with duodenal atresia had associated malformations. Thirty percent of the patients had Down's syndrome. End-to-side or side-to-side duodenoduodenostomy or jejunostomy are the most commonly used operative techniques for duodenal atresia. General anesthesia and tube gastrostomy are usually employed.

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