scholarly journals Are Lipids Possible Markers of Suicide Behaviors?

2021 ◽  
Vol 10 (2) ◽  
pp. 333
Author(s):  
Agnieszka Kułak-Bejda ◽  
Grzegorz Bejda ◽  
Magdalena Lech ◽  
Napoleon Waszkiewicz
Keyword(s):  
Suicide Risk ◽  
Biological Marker ◽  
Low Density Lipoproteins ◽  
Low Density ◽  
Lipid Levels ◽  
Mortality And Morbidity ◽  
Additional Tool ◽  
Cholesterol Levels ◽  
Causes Of Mortality ◽  
Suicide Behaviors

Suicides and suicidal behaviors are very important causes of mortality and morbidity and have become a serious global problem. More than 800,000 people die from suicide every year. Previous researches have established that lipids play an important role in the pathogenesis of suicide. Moreover, lipid levels might be a biological marker of suicide. A lot of researchers have tried to identify biological markers that might be related to depressive disorder, bipolar disorder or schizophrenia and suicidal behavior. It was also important to consider the usefulness of an additional tool for prevention actions. Metabolic deregulation, particularly low total cholesterol and low-density lipoproteins-cholesterol levels may cause higher suicide risk in patients with these psychiatric disorders.

Secondary prevention care and effect: Total and low-density lipoprotein cholesterol levels and lipid-lowering drug use in women and men after incident myocardial infarction – The Tromsø Study 1994–2016

2018 ◽  
Vol 17 (6) ◽  
pp. 563-570 ◽  
Author(s):  
Laila A Hopstock ◽  
Anne Elise Eggen ◽  
Maja-Lisa Løchen ◽  
Ellisiv B Mathiesen ◽  
Inger Njølstad ◽  
...  
Keyword(s):  
Ldl Cholesterol ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Lipid Lowering ◽  
Low Density ◽  
Lipid Levels ◽  
Treatment Target ◽  
Cholesterol Levels ◽  
Lipid Lowering Drug ◽  
Lowering Drug

Background: Secondary prevention guidelines after myocardial infarction (MI) are gender neutral, but underutilisation of treatment in women has been reported. Design: We investigated the change in total and low-density lipoprotein (LDL) cholesterol levels and lipid-lowering drug (LLD) use after first-ever MI in a population-based study. Methods: We followed 10,005 participants (54% women) attending the Tromsø Study 1994–1995 and 8483 participants (55% women) attending the Tromsø Study 2007–2008 for first-ever MI up to their participation in 2007–2008 and 2015–2016, respectively. We used linear and logistic regression models to investigate sex differences in change in lipid levels. Results: A total of 395 (MI cohort I) and 132 participants (MI cohort II) had a first-ever MI during 1994–2008 and 2007–2013, respectively. Mean change in total cholesterol was −2.34 mmol/L (SD 1.15) in MI cohort I, and in LDL cholesterol was −1.63 mmol/L (SD 1.12) in MI cohort II. Men had a larger decrease in lipid levels compared to women: the linear regression coefficient for change was −0.33 (95% confidence interval [CI] −0.51 to −0.14) for total cholesterol and −0.21 (95% CI −0.37 to −0.04) for LDL cholesterol, adjusted for baseline lipid value, age and cohort. Men had 73% higher odds (95% CI 1.15−2.61) of treatment target achievement compared to women, adjusted for baseline lipid value, age and cohort. LLD use was reported in 85% of women and 92% of men in MI cohort I, and 80% in women and 89% in men in MI cohort II. Conclusions: Compared to men, women had significantly less decrease in lipid levels after MI, and a smaller proportion of women achieved the treatment target.

Serum low density lipoproteins, triglycerides and cholesterol levels in malaysia

1971 ◽  
Vol 34 (1) ◽  
pp. 85-92 ◽  
Author(s):  
Y.H. Chong ◽  
C.C. Soh ◽  
G.S. Ho ◽  
R. Rajaratnam ◽  
P. Nonis
Keyword(s):  
Low Density Lipoproteins ◽  
Low Density ◽  
Cholesterol Levels

scholarly journals Genetic variation in serum low density lipoproteins and lipid levels in man.

1976 ◽  
Vol 73 (3) ◽  
pp. 937-940 ◽  
Author(s):  
K. Berg ◽  
C. Hames ◽  
G. Dahlen ◽  
M. H. Frick ◽  
I. Krishan
Keyword(s):  
Genetic Variation ◽  
Low Density Lipoproteins ◽  
Low Density ◽  
Lipid Levels

Lipid Levels in Schoolchildren in North East England: Effects of Feeding and Age

1994 ◽  
Vol 31 (3) ◽  
pp. 233-239 ◽  
Author(s):  
K Azad ◽  
S Court ◽  
J M Parkin ◽  
M F Laker ◽  
K G M M Alberti
Keyword(s):  
Ldl Cholesterol ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Hdl Cholesterol ◽  
Low Density ◽  
Lipid Levels ◽  
North East ◽  
Cholesterol Levels ◽  
Log Normal ◽  
Effect Of Feeding

Serum total cholesterol, high-density lipoprotein (HDL) cholesterol, triglyceride, apolipoprotein (apo) A-I and apoB concentrations were estimated and low-density lipoprotein (LDL) cholesterol levels were calculated in 132 children aged 11·4–17·3 years. The effect of feeding was investigated by estimating postprandial values and also by studying the effects of a test meal. The distribution of all data was consistent with Gaussian apart from triglycerides which was log normal. Overall fasting values were [mean (standard deviation; SD)] cholesterol 4·5 (0·8) mmol/L, HDL cholesterol 1·5 (0·4) mmol/L, LDL cholesterol 2·6 (0·8) mmol/L, apoA-I 1·5 (0·3) g/L, apoB 1·0 (0·4) g/L and triglycerides 0·76 (0·38–1·51) mmol/L, the values for triglycerides being mean (95% confidence intervals). Girls had higher triglycerides than boys [0·82 (0·43–1·54) versus 0·70 (0·36–1·33)] and different effects of age on lipids were found, HDL cholesterol being negatively correlated with age in boys ( r= −0·37; P<0·001), but not in girls, and apoA-I being negatively correlated with age in boys ( r= −0·31; P=0·006), but positively correlated with age in girls ( r = 0·32; P = 0·008). Triglycerides rose and HDL cholesterol fell following feeding and inconsistent effects were seen on apoA-I and apoB.

scholarly journals Dyslipidemia in psoriasis patients: a case-control study

2019 ◽  
Vol 5 (1) ◽  
pp. 101
Author(s):  
Surinder Gupta ◽  
Preeti Garg ◽  
Nakul Gupta
Keyword(s):  
Case Control Study ◽  
Case Control ◽  
Low Density Lipoproteins ◽  
High Density Lipoproteins ◽  
Medical Institute ◽  
Inflammatory Disorder ◽  
Low Density ◽  
Very Low Density Lipoproteins ◽  
Mortality And Morbidity ◽  
Control Study

<p class="abstract"><strong>Background:</strong> Psoriasis is a chronic inflammatory disorder with defective proliferation and differentiation of keratinocytes. It is associated with metabolic syndrome i.e. dyslipidemia, hypertension, obesity, cardiovascular diseases and insulin resistance. The high incidence of cardiovascular events in psoriasis is highly associated with abnormal lipid metabolism. This case-control study was done in North Indian medical institute to investigate the levels of serum lipids in psoriasis patients taking in account various parameters like weight, height, body mass index, blood pressure and diabetes.</p><p class="abstract"><strong>Methods:</strong> We assessed the fasting lipid profile in 48 psoriasis patients and 48 healthy, age and sex matched controls.<strong></strong></p><p class="abstract"><strong>Results:</strong> The study found significant elevation (p&lt;0.05) of serum total cholesterol, triglycerides, low density lipoproteins (LDL) and very low density lipoproteins (VLDL) in psoriasis patients compared to controls. The levels of high density lipoproteins (HDL) were also significantly lower (p&lt;0.05) in psoriasis patients.</p><p class="abstract"><strong>Conclusions:</strong> This study suggests that psoriasis is a high risk disorder for cardiovascular mortality and morbidity because of its association with dyslipidemia.</p><p> </p>

scholarly journals Alterations of serum lipid profile in oral submucous fibrosis

2017 ◽  
Vol 3 (4) ◽  
pp. 1064 ◽  
Author(s):  
K. Mallikarjuna Swamy ◽  
Arati Ganiger
Keyword(s):  
Lipid Profile ◽  
Serum Lipid ◽  
Oral Submucous Fibrosis ◽  
Low Density Lipoproteins ◽  
Serum Lipid Profile ◽  
Low Density ◽  
Healthy Controls ◽  
Lipid Levels ◽  
Submucous Fibrosis ◽  
The Relationship

<p class="abstract"><strong>Background:</strong> Oral cancer is one of the most common form of malignancies in India. In many cases it develops at the site of premalignant lesion. Of all oral premalignant conditions, oral submucous fibrosis (OSMF) is of greater concern because of its disabling nature and relative greater chances of malignant transformation. This study is aimed to evaluate the serum lipid profile in OSMF patients as the change in lipid levels may have a diagnostic and prognostic role in the potentially malignant lesions. The present study aimed to evaluate the alteration in serum lipid profile in OSMF and to compare them with healthy controls and to correlate the relationship between pathogenesis of OSMF and lipid profile.</p><p class="abstract"><strong>Methods:</strong> It is a case control study. The study included 50 diagnosed cases of OSMF and 50 matched healthy controls. Fasting venous blood of 3 ml was collected in both cases and controls and serum was separate. Fasting serum lipid profile including total cholesterol (TC), very low density lipoproteins (VLDL), low density lipoproteins (LDL), high density lipoproteins (HDL) and triglycerides (TG) were measured using automatic analyser. Statistical analysis was done using student 't' test .Pearson's correlation  was performed to establish the relationship between study variables.  </p><p class="abstract"><strong>Results:</strong> It was observed that there was statistically significant decrease in serum total cholesterol, TG, LDL, VLDL and HDL observed in patients with OSMF  as compared to the control group (p&lt;0.005).</p><p><strong>Conclusions:</strong> The low lipid levels associated with OSMF indicates that there is inverse relationship between oral cancer and serum lipid profile. Decrease in the lipid levels may be considered as a valuable biochemical marker in the early diagnosis and prognosis of oral malignancy. </p>

scholarly journals FEEDING LOCAL FERMENTED WITH EM-4, AMMONIUM SULFATE, AND UREA ON THE BLOOD FAT LEVEL OF MALE DUCK

2020 ◽  
Vol 14 (2) ◽  
Author(s):  
Dian Septinova ◽  
Aisyah Yuli Arti ◽  
Rudy Sutrisna ◽  
Syahrio Tantalo ◽  
Madi Hartono
Keyword(s):  
High Density Lipoprotein ◽  
Ammonium Sulfate ◽  
Density Lipoprotein ◽  
Low Density Lipoproteins ◽  
Low Density ◽  
Cholesterol Levels ◽  
Randomized Design ◽  
Fermented Feed ◽  
Fat Level ◽  
Completely Randomized Design

The objective of this study was to determine the effect of commercial ration by the addition of ammonium sulfate and urea fermented feed ingredients on the blood fat levels of local male ducks. This study used a completely randomized design with 32 male ducks which weredivided into four groups namely R0, R1, R2, R3, and R4. Each group was given the following treatment: R0 only given commercial ration;R1 was given 80% commercial ration + 20% fermentation of EM-4 + 1.5% urea); R2 was given 80% commercial ration + 20% EM-4 + 1.5%ammonium sulfate fermentation; and R3 was given 80% commercial ration + 20% EM-4 + 1.5% urea + 1.5% ammonium sulfate. Variablesin this study were blood fat consisting of cholesterol, triglyceride, High-Density Lipoprotein (HDL), and Low-Density Lipoproteins (LDL).The data obtained were analyzed by using 5% real level and LSD. The results showed that the provision of commercial ration added withlocal feed fermented with ammonium sulfate and urea had a significant effect on cholesterol levels (P0.5), but not significant (P0.05) ontriglyceride, HDL, and LDL levels. Furthermore, the ration that gave the best effect on the blood fat levels of male ducks blood was the ration given to R3 group.

scholarly journals Serum lipid levels in pregnancies complicated by preeclampsia

2011 ◽  
Vol 129 (2) ◽  
pp. 73-76 ◽  
Author(s):  
Valmir Jose de Lima ◽  
Claudia Roberta de Andrade ◽  
Gustavo Enrico Ruschi ◽  
Nelson Sass
Keyword(s):  
Pregnant Women ◽  
Serum Levels ◽  
Low Density Lipoproteins ◽  
High Density Lipoproteins ◽  
Low Density ◽  
Lipid Levels ◽  
Very Low Density Lipoproteins ◽  
Cross Sectional ◽  
Gestational Week ◽  
Elevated Lipid

CONTEXT AND OBJECTIVE: Pre-eclampsia is a disorder that occurs only during pregnancy. Postpartum changes relating to lipid metabolism may contribute towards the endothelial lesions observed in preeclampsia. Thus, the aim of the present study was to evaluate the lipid profile among patients who present preeclampsia and correlate these parameters with 24-hour proteinuria. DESIGN AND SETTING: Cross-sectional analytical study including 77 pregnant patients seen at Hospital Dório Silva. METHODS: This study involved 42 women with preeclampsia and 35 healthy pregnant women in the third trimester of pregnancy as controls. Blood samples were obtained from all the patients, and the serum levels of triglycerides, total cholesterol, low-density lipoproteins (LDL), high-density lipoproteins (HDL) and very low density lipoproteins (VLDL) were determined. Cases and controls were matched for maternal age, gestational week and body mass index. RESULTS: The VLDL and triglyceride values from the women with preeclampsia were significantly higher than those of the healthy women. There was a positive correlation between increased proteinuria and higher VLDL and triglyceride levels in patients with preeclampsia. CONCLUSION: Among the patients with preeclampsia, higher VLDL and triglyceride levels were positively correlated with proteinuria. These observations indicate that the pregnant women who presented elevated lipid levels were more susceptible to cardiovascular disorders and, consequently, pre-eclampsia.

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