Maskne: Exacerbation or Eruption of Acne During the COVID-19 Pandemic

Although the COVID-19 outbreak has decreased dermatology outpatient clinic visits, acne remains the most common condition among patients requesting an appointment. The widespread use of face masks may be a contributing factor to acne mechanica and folliculitis mechanica, where stopping the mechanical insult is essential to treatment. However, COVID-19 poses a unique challenge as mask wearing is crucial to limiting viral exposure. Although reported cases of mask-associated facial dermatoses are largely documented in healthcare workers, the general population is being affected by “maskne”. Pathogenesis and treatment options are discussed and the importance of counseling patients on proper skin hygiene is highlighted. As mask use increases, dermatologists should anticipate this trend in acne flare-ups.

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AYURVEDIC PREPARATIONS FOR THE MANAGEMENT OF THE RAS - A REVIEW

Indian Journal of Medical Research and Pharmaceutical Sciences - September-2020 ◽

10.29121/ijmrps.v7.i9.2020.1 ◽

2020 ◽

Vol 7 (9) ◽

pp. 1-8

Keyword(s):

General Population ◽

Herbal Medicines ◽

Sudden Increase ◽

Herbal Extracts ◽

Common Condition ◽

Etiological Factors ◽

Oral Ulcers ◽

Alternative Approach

Oral ulcers are the most common condition in the general population and are caused by a variety of etiological factors. It often causes pain and discomfort. So, there are different treatments including herbal medicines that have been used for oral ulcers. Nowadays, there has been a sudden increase in the use of herbal extracts as an alternative approach to modern-day medicines. So, this review focuses on the ayurvedic preparations for the treatment of RAS.

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SARS-CoV-2 Ig G among Healthcare Workers and the General Population

Pathogens ◽

10.3390/pathogens10040465 ◽

2021 ◽

Vol 10 (4) ◽

pp. 465

Author(s):

Gregorio P. Milani ◽

Mario G. Bianchetti ◽

Giuseppe Togni ◽

Andreas W. Schoenenberger ◽

Franco Muggli

Keyword(s):

General Population ◽

Healthcare Workers ◽

Geographical Area ◽

Healthcare Personnel ◽

Protein Subunit ◽

Positive Serology ◽

Seroprevalence Data ◽

And Gender ◽

Few Data ◽

Ig G

It is assumed that healthcare workers are at the highest risk to be infected by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, few data from healthcare workers who do not primarily take care of patients with SARS-CoV-2 infection support this assumption. We investigated the prevalence of immunoglobulin G (Ig G) against SARS-CoV-2 among healthcare workers who do not primarily take care of patients with SARS-CoV-2 infection and the general population in a well-defined geographical area. The first part of the study was conducted in May 2020 in Val Mesolcina (Southern Switzerland), a valley with ~8000 inhabitants. All healthcare workers were invited. All participants (n = 488) of the Swiss Longitudinal Cohort Study (SWICOS), a cohort representative of the general population, were also invited. Circulating Ig G against spike protein subunit 1 of SARS-CoV-2 were tested in each subject. Subjects with positive Ig G were tested again after 6 months. The condition of being a healthcare worker, rather than a part of the general population, was tested as a predictor of seroprevalence positivity by both simple and multiple (adjusted for age and sex) logistic regression. Eleven (2.6%) of the 423 SWICOS participants and 46 (16%) out of 289 healthcare workers were positive for antibodies against SARS-CoV-2. The seroprevalence OR was 7.01 (95% CI: 3.53–15.47) for healthcare workers as compared to SWICOS participants. After adjusting for age and gender, the seroprevalence OR was 5.13 (95% CI: 2.54–10.40). About three quarters of the subjects in the SWICOS (73%) and in healthcare (79%) group with a previous positive serology still presented positive Ig G against the SARS-CoV-2 after 6 months. The present seroprevalence data point out that the SARS-CoV-2 infection is seven times higher among healthcare workers than in the general population of Val Mesolcina. Efforts to effectively protect all the healthcare personnel are needed.

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SARS-CoV-2 Seroprevalence among Healthcare Workers in General Hospitals and Clinics in Japan

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph18073786 ◽

2021 ◽

Vol 18 (7) ◽

pp. 3786

Author(s):

Tatsuya Yoshihara ◽

Kazuya Ito ◽

Masayoshi Zaitsu ◽

Eunhee Chung ◽

Izumi Aoyagi ◽

...

Keyword(s):

Public Health ◽

Social Support ◽

General Population ◽

Severe Acute Respiratory Syndrome ◽

Immunoglobulin G ◽

Health Problem ◽

Healthcare Workers ◽

Public Health Problem ◽

General Hospitals ◽

Second Wave

Coronavirus disease 2019 (COVID-19) has become a serious public health problem worldwide. In general, healthcare workers are considered to be at higher risk of COVID-19 infection. However, the prevalence of COVID-19 among healthcare workers in Japan is not well characterized. In this study, we aimed to examine the seroprevalence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) antibodies among 2160 healthcare workers in hospitals and clinics that are not designated to treat COVID-19 patients in Japan. The prevalence of SARS-CoV-2 immunoglobulin G was 1.2% in August and October 2020 (during and after the second wave of the pandemic in Japan), which is relatively higher than that in the general population in Japan (0.03–0.91%). Because of the higher risk of COVID-19 infection, healthcare workers should be the top priority for further social support and vaccination against SARS-CoV-2.

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Psychosocial status during the prevalence of COVID-19 disease: the comparison between healthcare workers and general population

Current Psychology ◽

10.1007/s12144-021-01582-1 ◽

2021 ◽

Author(s):

Mohammad Ali Zakeri ◽

Sayed Mortaza Hossini Rafsanjanipoor ◽

Nadia Sedri ◽

Mahmood Kahnooji ◽

Mojtaba Sanji Rafsanjani ◽

...

Keyword(s):

General Population ◽

Healthcare Workers ◽

Psychosocial Status

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Real-World Acceptance of COVID-19 Vaccines among Healthcare Workers in Perinatal Medicine in China

Vaccines ◽

10.3390/vaccines9070704 ◽

2021 ◽

Vol 9 (7) ◽

pp. 704

Author(s):

Biyun Xu ◽

Xuelian Gao ◽

Xinyue Zhang ◽

Yali Hu ◽

Huixia Yang ◽

...

Keyword(s):

General Population ◽

Real World ◽

Healthcare Workers ◽

Vaccine Safety ◽

Vaccine Hesitancy ◽

Present Survey ◽

Perinatal Medicine ◽

Vaccine Acceptance ◽

Questionnaire Online ◽

Convincing Data

Surveys showed that vaccine hesitancy may influence the acceptance of COVID-19 vaccines in healthcare workers (HCWs) and the general population. Currently, the actual acceptance of COVID-19 vaccination in HCWs has rarely been reported. In the present survey, we investigated the real-world acceptance of COVID-19 vaccination in HCWs in perinatal medicine during the first three-month period of vaccination in China and to identify the main reason for the decline of vaccination. HCWs (1087) who participated in a Chinese national symposium on perinatal medicine during 16–18 April 2021 were invited to answer a 27-question questionnaire online. A total of 1051 HCWs completed the questionnaire. Of them, 86.2% (906/1051) accepted the COVID-19 vaccination and 13.8% (145/1051) declined the vaccination. Because of the vaccine hesitancy, one-fourth of the vaccinated participants did not accept the vaccination until consulted with others or requested by employers. The main reason for the decline of vaccination in 145 unvaccinated HCWs was the concern about vaccine safety. The results indicate that vaccination request by employers may promote vaccine acceptance. More convincing data on the safety of COVID-19 vaccines appears to be important to increase the acceptance of vaccination.

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Facing COVID-19 Pandemic in a Tertiary Hospital in Milan: Prevalence of Burnout in Nursing Staff Working in Sub-Intensive Care Units

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph18136684 ◽

2021 ◽

Vol 18 (13) ◽

pp. 6684

Author(s):

Alberto Bisesti ◽

Andrea Mallardo ◽

Simone Gambazza ◽

Filippo Binda ◽

Alessandro Galazzi ◽

...

Keyword(s):

Intensive Care ◽

Respiratory Failure ◽

Intensive Care Units ◽

Healthcare Workers ◽

Maslach Burnout Inventory ◽

Tertiary Hospital ◽

Personal Accomplishment ◽

Preventive Strategies ◽

Common Condition ◽

Hospital Units

In early March 2020, Italy became the epicenter of the Coronavirus Disease 2019 (COVID-19) pandemic in Europe. A different organization of hospital units was required to take care of patients affected by acute respiratory failure caused by COVID-19. This study aimed to evaluate the prevalence of burnout in two sub-intensive care units (SICUs) of the COVID-19 hub center of the Lombardia region in Milan (Italy). All nurses and healthcare assistants working in the SICUs during June 2020 were included in the study. Burnout was assessed via the Maslach Burnout Inventory questionnaire. One hundred and five (84%) SICU staff participated in the study. The prevalence of high burnout for nurses and healthcare assistants was 61.9% for emotional exhaustion, 47.6% for depersonalization and 34.3% for personal accomplishment. Depersonalization was significantly more frequent in younger nurses (p = 0.009). Nurses were 4.5 times more likely to have burnout than healthcare assistants. Burnout was a common condition among healthcare workers operating in SICUs during the pandemic. Urgent actions are needed, especially for nurses, as well as preventive strategies for future pandemic scenarios.

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Skin Barrier Damage due to Prolonged Mask Use among Healthcare Workers and the General Population during the COVID-19 Pandemic: A Prospective Cross-Sectional Survey in China

Dermatology ◽

10.1159/000517219 ◽

2021 ◽

pp. 1-8

Author(s):

Xiao Wan ◽

Quansheng Lu ◽

Dandan Sun ◽

Hong Wu ◽

Guan Jiang

Keyword(s):

General Population ◽

Healthcare Workers ◽

Response Rate ◽

Skin Barrier ◽

Population History ◽

Skin Damage ◽

Cross Sectional ◽

Effective Response ◽

Skin Injuries ◽

Popularization Of Science

Background: Coronavirus disease 2019 (COVID-19) has resurged in localized areas in China. Individuals wear masks to prevent the spread of droplets. However, skin barrier damage occurs because of the prolonged use of masks. Objective: To investigate the prevalence and associated risk factors of skin injuries among healthcare workers (HCWs) and the general population during the COVID-19 outbreak. Methods: A multicenter cross-sectional study of skin barrier damage caused by wearing masks was conducted using an online questionnaire between December 10 and December 31, 2020. Data regarding demographics, characteristics of facial skin damage, and information on masks were registered. Multivariate logistic regression was used to analyze factors associated with skin barrier damage, and odds ratios (OR) with 95% confidence intervals (CI) were used to establish correlation strength. Results: A total of 1,538 responses were retrieved from 1,700 questionnaires (response rate, 90.47%), and 1,409 questionnaires were valid (effective response rate, 91.61%). The respondents comprised 567 HCWs (40.24%) and 842 individuals from the general population (59.76%). The prevalence of skin injuries was 46.03% among HCWs and 46.20% among the general population. History of chronic skin disease (OR, 6.01; 95% CI, 4.75–7.75), type of mask used (OR, 2.77; 95% CI, 1.95–3.93), daily wearing time (OR, 1.57; 95% CI, 1.36–1.82), and mask replacement cycle (OR, 0.76; 95% CI, 0.68–0.86) were associated with skin barrier damage. Conclusion: There was a high incidence of skin barrier damage due to prolonged mask use among HCWs and the general population, and treatment and prevention were inadequate. Attention needs to be given to strengthening comprehensive health education and popularization of science.

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Health-Related Quality of Life in Adrenocortical Carcinoma

Cancers ◽

10.3390/cancers11101500 ◽

2019 ◽

Vol 11 (10) ◽

pp. 1500 ◽

Cited By ~ 1

Author(s):

Rebecca V. Steenaard ◽

Laura A. Michon ◽

Harm R. Haak

Keyword(s):

Quality Of Life ◽

General Population ◽

Adrenocortical Carcinoma ◽

Treatment Options ◽

Clinical Aspects ◽

Health Related Quality ◽

Related Quality ◽

Health Related ◽

The Impact

Insight into the health-related quality of life (HRQoL) impact of adrenocortical carcinoma (ACC) is important. The disease and its treatment options potentially have an impact on HRQoL. For patients with limited survival, HRQoL research is of utmost importance. We will therefore provide an overview of HRQoL studies in patients with ACC. We found six studies that measured HRQoL in 323 patients with ACC (3 cross-sectional, 1 cohort, 2 trials), all indicating a reduced HRQoL compared to the general population. The FIRMACT trial found that HRQoL of patients with ACC was reduced compared to the general population, and that chemotherapy-mitotane further reduced HRQoL even though survival improved. Clinical aspects of the disease, including cortisol and aldosterone production and adrenal insufficiency have shown great impact on HRQoL in benign disease, even after the recovery of hormonal status. However, the impact of malignant adrenal disease and treatment options on HRQoL including adrenalectomy, radiotherapy, mitotane therapy, and chemotherapy have not been sufficiently studied in patients with ACC. Although the number of HRQoL studies in patients with ACC is limited, the existing literature does indicate that ACC has a large impact on patients’ HRQoL, with disease specific aspects. Further HRQoL research in patients with ACC is essential to improve patient-centered care, preferably by using an ACC-specific HRQoL questionnaire.

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Outpatient clinic visits during heat waves: findings from a large family medicine clinical database

Family Practice ◽

10.1093/fampra/cmy013 ◽

2018 ◽

Vol 35 (5) ◽

pp. 567-570 ◽

Cited By ~ 1

Author(s):

Devesh Vashishtha ◽

William Sieber ◽

Brittany Hailey ◽

Kristen Guirguis ◽

Alexander Gershunov ◽

...

Keyword(s):

Family Medicine ◽

Outpatient Clinic ◽

Heat Waves ◽

Large Family ◽

Clinical Database ◽

Clinic Visits

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Patterns of Survival Among Patients With Myeloproliferative Neoplasms Diagnosed in Sweden From 1973 to 2008: A Population-Based Study

Journal of Clinical Oncology ◽

10.1200/jco.2012.42.1925 ◽

2012 ◽

Vol 30 (24) ◽

pp. 2995-3001 ◽

Cited By ~ 112

Author(s):

Malin Hultcrantz ◽

Sigurdur Yngvi Kristinsson ◽

Therese M.-L. Andersson ◽

Ola Landgren ◽

Sandra Eloranta ◽

...

Keyword(s):

General Population ◽

Life Expectancy ◽

Excess Mortality ◽

Myeloproliferative Neoplasms ◽

Treatment Options ◽

Large Population ◽

Relative Survival ◽

Population Based ◽

Population Based Study ◽

Over Time

PurposeReported survival in patients with myeloproliferative neoplasms (MPNs) shows great variation. Patients with primary myelofibrosis (PMF) have substantially reduced life expectancy, whereas patients with polycythemia vera (PV) and essential thrombocythemia (ET) have moderately reduced survival in most, but not all, studies. We conducted a large population-based study to establish patterns of survival in more than 9,000 patients with MPNs.Patients and MethodsWe identified 9,384 patients with MPNs (from the Swedish Cancer Register) diagnosed from 1973 to 2008 (divided into four calendar periods) with follow-up to 2009. Relative survival ratios (RSRs) and excess mortality rate ratios were computed as measures of survival.ResultsPatient survival was considerably lower in all MPN subtypes compared with expected survival in the general population, reflected in 10-year RSRs of 0.64 (95% CI, 0.62 to 0.67) in patients with PV, 0.68 (95% CI, 0.64 to 0.71) in those with ET, and 0.21 (95% CI, 0.18 to 0.25) in those with PMF. Excess mortality was observed in patients with any MPN subtype during all four calendar periods (P < .001). Survival improved significantly over time (P < .001); however, the improvement was less pronounced after the year 2000 and was confined to patients with PV and ET.ConclusionWe found patients with any MPN subtype to have significantly reduced life expectancy compared with the general population. The improvement over time is most likely explained by better overall clinical management of patients with MPN. The decreased life expectancy even in the most recent calendar period emphasizes the need for new treatment options for these patients.

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