An impact of intima media thickness of carotids in cardio vascular profile

2020 ◽  
Vol 10 (2) ◽  
pp. 48-52
Author(s):  
Jeevitha M ◽  
Kalaichandar M ◽  
Kirubakaran K ◽  
Baskaran V ◽  
Kokila K ◽  
...  

Low blood pressure truly includes a worse prognosis than the excessive blood strain. This mechanism,bills for the "reverse causation "seen within the haemodialysis’ patients, the company of conventional risk elements, such as high blood pressure, hyperlipidemia, and obesity, appear to be a worst diagnosis.Exogenous erythropoietic products can growth blood strain and requirement of antihypertensive tablets.30 Chronic ECFV overload secondary to activation of renin-angiotensin-aldosterone axisand disturbances inside the stability of vasoconstrictors and the vasodilators make a contribution to high blood pressure. Improvement in blood pressure can be introduced out with oral sodium restriction, diuretics, and fluid elimination with dialysis. Some patients will continue to be hypertensive notwithstanding of the careful attention to ECFV reputation. LVH is related with reduced endurance of sufferers on hemo/peritoneal dialysis .Lower five year survival charge in ESRD patients with LVH have a 30% than people missing LVH. This have a look at produces the mean carotid artery intima-medial thickness turned into higher in sufferers with superior CKD although it did now not attain statistical significance, probable due to smaller sample size.It was also observed that carotid intima medial thickness had no correlation with dyslipidemia. Even though the patients had maintained significantly normal cholesterol and high HDL levels, there was an increase in CIMT. Therefore, CKD patients, CIMT cannot be predicted based on the traditional atherosclerotic risk factors like serum cholesterol and HDL.

Author(s):  
Talluri Jagadeesh ◽  
Potlacheruvu Anusha ◽  
Reddyboyina Haripriya

Low blood pressure indeed includes a worse prognosis than excessive blood strain. This mechanism, bills for the "reverse causation "seen within the ’ patients, the company of conventional risk elements, such as high blood pressure, , and obesity, appear to be the worst diagnosis. Exogenous products can growth blood strain and requirement of tablets.30 Chronic ECFV overload secondary to activation of axis and disturbances inside the stability of and the contributes to high blood pressure. Improvement in blood pressure can be introduced out with oral sodium restriction, diuretics, and fluid elimination with dialysis. Some patients will continue to be hypertensive notwithstanding of the careful attention to ECFV reputation.LVH is related to reduced endurance of sufferers on /peritoneal dialysis. Lower five-year survival charge in ESRD patients with LVH has a 30%than people missing LVH. This has a look at produces the mean carotid artery thickness turned into higher in sufferers with superior CKD. However, it did now not attain statistical significance, probable due to the smaller sample size. It was also observed that carotid medial thickness did not correlate with . Even though the patients had maintained significantly healthy cholesterol and high HDL levels, there was an increase in CIMT. in CKD patients, CIMT cannot be predicted based on the traditional atherosclerotic risk factors like serum cholesterol and HDL.


2020 ◽  
Vol 10 (9) ◽  
pp. 3214
Author(s):  
Muhammad Tahir ◽  
Muhammad Usman ◽  
Fazal Muhammad ◽  
Shams ur Rehman ◽  
Imran Khan ◽  
...  

High Blood Pressure (BP) is a vital factor in the development of cardiovascular diseases worldwide. For more than a decade now, patients search for quality and easy-to-read Online Health Information (OHI) for symptoms, preventions, therapy and other medical conditions. In this paper, we evaluate the quality and readability of OHI about high BP. In order that the first 20 clicks of three top-rated search engines have been used to collect the pertinent data. Using the exclusion criteria, 25 unique websites are selected for evaluation. The quality of all included links is evaluated through DISCERN checklist, a questionnaire for assessing the quality of written information for a health problem. To enhance the reliability of evaluation, all links are separately assessed by two different groups—a group of Health Professional (HPs) and a group of Lay Subjects (LS). A readability test is performed using Flesch-Kincaid tool. Fleiss’ kappa has been calculated before considering average value of each group. After evaluation, the average DISCERN value of HPs is 49.43 ± 14.0 (fair quality) while for LS, it is 48.7 ± 12.2; the mean Flesch-Reading Ease Score (FRES) is 58.5 ± 11.1, which is fairly difficult to read and the Average Grade Level (AGL) is 8.8 ± 1.9. None of the websites scored more than 73 (90%). In both groups, only 4 (16%) websites achieved DISCERN score over 80%. Mann-Whitney and Cronbach’s alpha have been computed to check the statistical significance of the difference between two groups and internal consistency of DISCERN checklist, respectively. Normality and homoscedasticity tests have been performed to check the distribution of scores of both evaluating groups. In both groups, information category websites achieved high DISCERN score but their readability level is worse. Highest scoring websites have clear aim, succinct source and high quality of information on treatment options. High BP is a pervasive disease, yet most of the websites did not produce precise or high-quality information on treatment options.


Vascular ◽  
2020 ◽  
Vol 28 (4) ◽  
pp. 405-412
Author(s):  
Oscar H Del Brutto ◽  
Victor J Del Brutto ◽  
Robertino M Mera ◽  
Aldo F Costa ◽  
Rubén Peñaherrera ◽  
...  

Objective Information on the associations among arterial stiffness, carotid intima-media thickness (cIMT) and carotid plaques as biomarkers of atherosclerosis is limited in diverse populations. We aimed to assess whether aortic pulse wave velocity (aPWV) – as a surrogate of arterial stiffness – is associated with increased cIMT and the presence of carotid plaques in a cohort of older adults of Amerindian ancestry. Methods Atahualpa residents aged ≥60 years ( n = 320) underwent aPWV determinations, and carotid ultrasounds for cIMT and plaque assessment. Multivariate models were fitted to assess the independent association between the aPWV, and cIMT and carotid plaques, after adjusting for relevant confounders. Differences in risk factors across these biomarkers were investigated. Results Mean values of aPWV were 10.3 ± 1.8 m/s, and those of cIMT were 0.91 ± 0.21 mm (24% had a cIMT >1 mm). Carotid plaques were observed in 118 (37%) subjects. In univariate analyses, risk factors associated with an increased aPWV included age, female gender, poor physical activity and high blood pressure. An increased cIMT was associated with age, male gender, a poor diet, high blood pressure and severe tooth loss. The presence of carotid plaques was associated with increasing age, poor physical activity and high blood pressure. Multivariate models showed a significant association between aPWV and cIMT (β: 0.028; 95% C.I.: 0.001–0.056; p =  0.047) but not between aPWV and carotid plaques (OR: 1.14; 95% C.I.: 0.83–1.56; p =  0.423). Conclusions This study shows an independent association between aPWV and cIMT but not with carotid plaques. These biomarkers may indicate distinct phenotypes for atherosclerosis.


2017 ◽  
Vol 27 (7) ◽  
pp. 1295-1305 ◽  
Author(s):  
Thomas G. Day ◽  
MinHae Park ◽  
Sanjay Kinra

AbstractHigh blood pressure is a risk factor for atherosclerosis in adults, but whether the same is true in children and young people is not known. This is important to guide management of high blood pressure in children and young people. We aimed to investigate the association in children and young people between blood pressure and carotid intima-media thickness, a non-invasive marker of atherosclerosis, through a systematic review. Studies were retrieved from MEDLINE and EMBASE. Articles were eligible for inclusion if they included at least one measurement of blood pressure and at least one measurement of ultrasound-derived carotid intima-media thickness, both measured during childhood (0–19 years), and a measure of effect size or correlation between the two measurements. A total of 3748 studies were identified in the initial search, of which 28 studies were included in this review. The results were mixed, but the largest and highest-quality studies suggested an independent positive association between blood pressure and carotid intima-media thickness in children and young people, even after adjustment for other cardiovascular risk factors. There was no indication of a clear threshold level for the effect of blood pressure on carotid intima-media thickness, hence there are insufficient data to support a pharmacological treatment threshold for the treatment of high blood pressure in children and young people to prevent future cardiovascular disease. The studies included varied widely in terms of quality and design, and it was not possible to combine the data in a meta-analysis. There is likely to be an independent association between blood pressure and carotid intima-media thickness in childhood, but it is not clear at what point this should be treated.


Author(s):  
Yudhisman Imran ◽  
Pukovisa Prawiroharjo ◽  
Martiem Mawi

Background<br />Atherosclerosis is initiated by endothelial dysfunction, as a result of increasing degradation of nitrit oxide by reactive oxygen species, thereby increasing oxydative stress. Dyslipidemia is one of the risk factors of endothelial dysfunction. The aim of this study was to evaluate the relationship of blood pressure and serum lipid level with carotid intima-media thickness (CIMT) in subjects aged between 55-65 years.<br /><br />Methods<br />A cross sectional study was carried out in 52 male and female subjects aged between 55-65 years. Age, gender, body mass index (BMI), blood pressure, lipid profile, and CIMT were assessed in all subjects. The independent t-test was used to to analyze the relationship between all variables and CIMT. The level of statistical significance was set at p&lt;0.05<br /><br />Results<br />Mean age was 59.19 ± 3.68 years, prevalence of thickened CIMT was 66.5%, and plaques were found in 9 subjects. There wwre no significant differences in age, BMI, systolic and diastolic blood pressure, and lipid profile between normal and thickened CIMT (p&gt;0.05). However, there was a significant difference in gender between the two groups (p=0.011). In females, mean systolic and diastolic blood pressure were higher in the thickened CIMT group than in the normal CIMT group, but the difference was not significant (p&gt;0.05). <br /><br />Conclusions<br />Our findings suggest that high blood pressure tends to increase CIMT in female adults. An increasing value of CIMT should be considered as a sign of cerebrovascular disease.


2015 ◽  
Vol 4 (3) ◽  
pp. 16
Author(s):  
Yun Wu

<strong>Objective:</strong> To observe the clinical symptoms of diabetes patients with high blood pressure, highlighting the influence and application value of nursing intervention on diabetic patients with hypertension. <strong>Methods: </strong>The data of 80 cases of diabetic patients with high blood pressure in our hospital from December 2011 to January 2011 were retrospectively analyzed. The patients were randomly divided into the experiment group and the control group. There were 40 patients of each group. Both patient groups were treated by the same means, subsequently, the control group were given routine nursing, while the experimental group were given programmed nursing to conduct care intervention. Finally, both clinical nursing effects were compared. <strong>Results:</strong> The numbers of patients with curative effect evaluation in the experimental group were marked higher than the control group patients. In terms of nursing satisfaction, the number of satisfied patients was larger than the control group, and the difference of the two groups was statistical significance (<em>p</em> &lt; 0.05). <strong>Conclusion:</strong> Nursing intervention can strengthen the therapeutic effect of drugs, help to improve the cognitive ability of diabetic patients clinically which also improves the quality of life of the patients.


2019 ◽  
Vol 23 (2) ◽  
pp. 275-285
Author(s):  
Yuri Han ◽  
Daehee Kang ◽  
Sang-Ah Lee

AbstractObjective:The present study aimed to examine the association between dietary pattern and the risk of high blood pressure (BP) and to estimate the attenuated effect by gender and obesity on the association using data from a prospective cohort study in Korea.Design:Prospective study. Diet was assessed using a validated 103-item FFQ and was input into factor analysis after adjustment for total energy intake.Setting:Community-based Korean Genome Epidemiology Study (KoGES) cohort.Participants:Healthy individuals (n 5151) without high BP at recruitment from the community-based cohort study.Results:Dietary pattern was not associated with the risk of high BP regardless of the type of covariates, with the exception of the ‘rice’ pattern. The effect of the ‘rice’ pattern was observed in both men (Ptrend = 0·013) and women (Ptrend < 0·001), but the statistical significance remained only in women after adjustment for confounders (Ptrend = 0·004). The positive association of the ‘rice’ pattern with high BP risk was attenuated by obesity. After stratification by gender and obese status, in particular, the harmful effect of the ‘rice’ pattern was predominantly observed in obese women (Ptrend < 0·001) only.Conclusions:This longitudinal study in Korean adults found a positive association of the ‘rice’ pattern with long-term development of incident high BP, predominantly in women. The association is likely to be attenuated by gender and obese status.


Stroke ◽  
2020 ◽  
Vol 51 (Suppl_1) ◽  
Author(s):  
Victor J Del Brutto ◽  
Oscar H Del Brutto ◽  
Robertino M Mera ◽  
Mark J Sedler ◽  
Aldo F Costa ◽  
...  

Background: Information on the associations among arterial stiffness, carotid intima-media thickness (cIMT) and carotid plaques as biomarkers of atherosclerosis is limited. We aimed to assess whether aortic pulse wave velocity (PWV) - as a surrogate of arterial stiffness - is associated with increased cIMT and the presence of carotid plaques in a cohort of older adults of Amerindian ancestry. Methods: Atahualpa residents aged ≥60 years (n=320) underwent aortic PWV determinations, and carotid ultrasound for cIMT and plaque assessment. Multivariate models were fitted to assess the independent association between the aortic PWV, and cIMT and carotid plaques (as dependent variables), after adjusting for relevant confounders. Differences in risk factors across these biomarkers were investigated. Results: Mean values of aortic PWV were 10.3±1.8 m/s, and those of cIMT were 0.91±0.21 mm (24% had a cIMT >1 mm). Carotid plaques were observed in 118 (37%) subjects. In univariate analyses, risk factors associated with an increased aortic PWV included age, female gender, poor physical activity and high blood pressure. An increased cIMT was associated with age, male gender, poor diet, high blood pressure and severe edentulism. The presence of carotid plaques was associated with increasing age, poor physical activity and high blood pressure. A fully-adjusted generalized linear model showed a significant association between aortic PWV and cIMT (β: 0.028; 95% C.I.: 0.001 - 0.056; p =0.047). In contrast, a logistic regression model showed no association between aortic PWV and carotid plaques (OR: 1.14; 95% C.I.: 0.83 - 1.56; p =0.423), after adjusting for relevant confounders. Conclusions: This study shows an independent association between aortic PWV and cIMT but not with carotid plaques. These biomarkers may indicate distinct phenotypes for atherosclerosis.


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