scholarly journals Effects of endothelins and matrix metalloproteinases in various pathological disorders and their antagonism at a better treatment modality in modern medicine

2020 ◽  
Vol 11 (3) ◽  
pp. 4608-4618
Author(s):  
Patta Prashant ◽  
Ramu Gogisetty ◽  
Vyshnavi Tallapaneni ◽  
Veera Venkata Satyanarayana Reddy Karri
Keyword(s):  
Heart Failure ◽  
Pulmonary Hypertension ◽  
Matrix Metalloproteinases ◽  
Modern Medicine ◽  
Endothelin Receptor ◽  
Significant Family History ◽  
The People ◽  
Type2 Diabetes ◽  
History Of ◽  
The Individual

Chronic disorders or diseases like hypertension, diabetes-mellitus, cancer, heart failure, pulmonary hypertension are becoming more prevalent nowadays even at a younger age. Various methods have been introduced to determine several diseases out of which the concept of measurement of endothelins and matrix metalloproteinases and the usage of endothelin receptor antagonist as a way of treatment either singly or combinedly with other drugs has achieved more importance. By the usage of serum matrix metalloproteinases (MMPs) and endothelins we can determine the people who are at risk of developing hypertension, type2 diabetes, heart failure, atherosclerosis, cancer, pulmonary hypertension and can also assess the range of complications that are going to occur in the individual. These elevated levels cause remodelling after a period of time. Hence, the detection is done through a method in which few factors like endothelins and MMPs of our body are measured through a blood sample, maximum benefits can be obtained in individuals who have a significant family history of developing hypertension and other conditions In this review we have discussed about various effects of endothelins in different conditions, and also to know if these conditions can be improved or not by using endothelin receptor antagonists.

Creative Tourism in Songkhla Lake Basin

2020 ◽  
Vol 11 (1) ◽  
pp. 126-126
Author(s):  
Dr.Prachyakorn Chaiyakot ◽  
Wachara Chaiyakhet ◽  
Dr.Woraluck Lalitsasivimol ◽  
Dr.Siriluck Thongpoon
Keyword(s):  
Local People ◽  
Lake Basin ◽  
Secondary Source ◽  
Tourist Attractions ◽  
The People ◽  
History Of ◽  
Tourism Resources ◽  
The Individual ◽  
Tourism Community ◽  
Songkhla Lake

Songkhla Lake Basin has a long history of at least 6,000 years and has a wide variety of tourism resources including nature, history, beliefs, culture and various traditions of the local people. It covers 3 provinces, the whole area of Phatthalung, 12 districts of Songkhla and 2 districts of Nakhon Si Thammarat Province. It has an area of approximately 8,727 square kilometers. There are many tourist attractions because the basin has a long history through different eras, natural, historic, ancient sites, and the culture of the local people. In 2018, both Thai and foreign tourists visited Songkhla and Phatthalung, which is the main area of Songkhla Lake Basin. The total number of tourists that came was 7,628,813 and 1,641,841 and an income of 68,252.64 and 3,470.96 million baht was generated from each province, respectively (Ministry of Tourism and Sports, 2020). Although Songkhla Lake Basin has various tourist attractions, the promotion of tourism with the involvement of government agencies in the past mainly focused on promoting tourism along with the tourist attractions rather than encouraging tourists to experience and learn the culture of the people living in the area; the culture that reflects the uniqueness of the people in the south. This study, therefore, aims to find creative tourism activities in SLB in order to increase the value of tourism resources, create tourism activities that are aligned with the resources available in the community and increase the number of tourists in the area. Data for this study were collected using a secondary source of data collection method. It was done through a literature review of related documents, texts, magazines, and research which focus on Songkhla Lake Basin as a guideline for designing tourism activities. The field survey was done through twelve community-based tourism sites in SLB to find creative tourism activities. Data on each activity were collected in detail by interviewing the tourism community leaders and the local people. Content analysis was used to describe the individual open-ended questions by focusing on the important issues and the information obtained was presented as a narrative. Keywords: Songkhla Lake Basin, Creative Tourism, Local Wisdom

Natural Law Republicanism

2021 ◽  
Author(s):  
Michael C. Hawley
Keyword(s):  
Natural Law ◽  
John Locke ◽  
Private Property ◽  
Political Legitimacy ◽  
John Adams ◽  
Political Ideas ◽  
The People ◽  
Hugo Grotius ◽  
History Of ◽  
The Individual

By any metric, Cicero’s works are some of the most widely read in the history of Western thought. This book suggests that perhaps Cicero’s most lasting and significant contribution to philosophy lies in helping to inspire the development of liberalism. Individual rights, the protection of private property, and political legitimacy based on the consent of the governed are often taken to be among early modern liberalism’s unique innovations and part of its rebellion against classical thought. However, this book demonstrates that Cicero’s thought played a central role in shaping and inspiring the liberal republican project. Cicero argued that liberty for individuals could arise only in a res publica in which the claims of the people to be sovereign were somehow united with a commitment to universal moral law, which limits what the people can rightfully do. Figures such as Hugo Grotius, John Locke, and John Adams sought to work through the tensions in Cicero’s vision, laying the groundwork for a theory of politics in which the freedom of the individual and the people’s collective right to rule were mediated by natural law. This book traces the development of this intellectual tradition from Cicero’s original articulation through the American founding. It concludes by exploring how modern political ideas remain dependent on the conception of just politics first elaborated by Rome’s great philosopher-statesman.

Attending to the Teacher in the Teaching: Prioritizing Faculty Well-Being

2021 ◽  
pp. 1-10
Author(s):  
Brianne H. Roos ◽  
Carey C. Borkoski
Keyword(s):  
Higher Education ◽  
Professional Learning ◽  
Well Being ◽  
Review Article ◽  
Faculty Members ◽  
High Expectations ◽  
The People ◽  
History Of ◽  
The Individual ◽  
The University

Purpose The purpose of this review article is to examine the well-being of faculty in higher education. Success in academia depends on productivity in research, teaching, and service to the university, and the workload model that excludes attention to the welfare of faculty members themselves contributes to stress and burnout. Importantly, student success and well-being is influenced largely by their faculty members, whose ability to inspire and lead depends on their own well-being. This review article underscores the importance of attending to the well-being of the people behind the productivity in higher education. Method This study is a narrative review of the literature about faculty well-being in higher education. The history of well-being in the workplace and academia, concepts of stress and well-being in higher education faculty, and evidence-based strategies to promote and cultivate faculty well-being were explored in the literature using electronic sources. Conclusions Faculty feel overburdened and pressured to work constantly to meet the demands of academia, and they strive for work–life balance. Faculty report stress and burnout related to excessively high expectations, financial pressures to obtain research funding, limited time to manage their workload, and a belief that individual progress is never sufficient. Faculty well-being is important for the individual and in support of scholarship and student outcomes. This article concludes with strategies to improve faculty well-being that incorporate an intentional focus on faculty members themselves, prioritize a community of well-being, and implement continuous high-quality professional learning.

scholarly journals The Updating in Satir’s Family Therapy Model

2017 ◽  
Vol 5 (1) ◽  
pp. 425
Author(s):  
Neşide Yıldırım
Keyword(s):  
Family Therapy ◽  
The United States ◽  
Communication Patterns ◽  
Self Confidence ◽  
Perspective Change ◽  
The People ◽  
The Family ◽  
The Status ◽  
History Of ◽  
The Individual

Virginia Satir (1916-1988) is one of the first experts who has worked in the field of family therapy in the United States. In 1951, she was one of the first therapists who has worked all members of the family as a whole in the same session. She has concentrated her studies on issues such as to increase individual's self-esteem and to understand and change other people's perspectives. She has tried to make problematic people compatible in the family and in the society through change. From this perspective, change and adaptation are the two important concepts of her model. This is a state of being and a way to communicate with ourselves and others. High self-confidence and harmony are the first primary indicator of being a more functional human. She starts her studies with identifying the family. She uses two ways to do this; the first one is the chronology of the family that is history of the family, the second one is the communication patterns within the family. With this, she updates the status of the family. Updating is the detection of the current situation. The detection of the situation, in other words updating, constitutes the very essence of the model that she implements. In this study, communication patterns within the family are discussed for the updating, the chronological structure has not been studied. The characteristics of family communication patterns, the model of therapy that is applied by Satir for these patterns and the method which is followed in the model are discussed. According to her detection, the people who face with problems, use one of those four patterns or a combination of them. These communication patterns are Blamer, Sedative/Accepting, distracter/irrelevant and rational. Satir expresses that these four patterns are not solid and unchanging but all of them “can be converted”. For example, if one of the family members is usually using the soothing (sedative/accepting) pattern, in this case, it means that he/she wants to give the message that he/she is not very important in the inner world of the individual itself. However, if such a communication pattern is to be used repeatedly by an individual, he/she must know how to use it. According to Satir, this consciousness may be converted to a conscious gentleness and sensitivity that is automatically followed to please everyone. This study was carried out by using the copy of Satir’s book, which was originally called “The Conjoint Family Therapy” and translated into Turkish by Selim Ali Yeniçeri as “Basic Family Therapy” and published in Istanbul by Beyaz Yayınları in 2016. It is expected that the study will provide support to the education of the students and family therapists.

Pilot Study of Endothelin Receptor Blockade in Heart Failure with Diastolic Dysfunction and Pulmonary Hypertension (BADDHY-Trial)

2017 ◽  
Vol 26 (5) ◽  
pp. 433-441 ◽  
Author(s):  
B. Koller ◽  
R. Steringer-Mascherbauer ◽  
C.H. Ebner ◽  
Th. Weber ◽  
M. Ammer ◽  
...  
Keyword(s):  
Heart Failure ◽  
Pulmonary Hypertension ◽  
Pilot Study ◽  
Diastolic Dysfunction ◽  
Receptor Blockade ◽  
Endothelin Receptor

The Eritrea Community-Based Theatre Project

1997 ◽  
Vol 13 (52) ◽  
pp. 386-395 ◽  
Author(s):  
Jane Plastow
Keyword(s):  
Women's Rights ◽  
Growth And Development ◽  
Modern Medicine ◽  
Women’S Rights ◽  
Community Based ◽  
The People ◽  
Freedom Fighters ◽  
History Of ◽  
Rural Context ◽  
First Time

Following Jane Plastow's contextual history of Eritrean theatre in NTQ50, Paul Warwick gave an account in the following issue of its previously undocumented role during the thirty-year Eritrean struggle for independence, describing the efforts of the freedom fighters to create theatre for the first time in a rural context. The Eritrean People's Liberation Front not only deployed theatre as a propaganda weapon, but also recognized its value as an agent for educating the people in matters ranging from women's rights to the benefits of modern medicine and farming methods: and with victory came measures further to stimulate the growth and development of theatre as part of Eritrean culture. Jane Plastow, in this third and concluding article, takes up the story with the invitation issued by the new government to her and her colleagues to initiate the ‘Eritrea Community-Based Theatre Project’, in an attempt both to widen the perspectives of Eritrean actors and to draw upon all relevant traditions, African and European, in developing a popular but distinctive theatre for the people. In addition to her role as director of the project, Jane Plastow is a lecturer at Leeds University, having worked in theatre for some years in a number of other African nations.

scholarly journals Favorable Evolution of a Patient with Thromboembolic Pulmonary Hypertension

2017 ◽  
Vol 23 (2) ◽  
pp. 94-98
Author(s):  
Cristina Nedelcu ◽  
Irinel Raluca Parepa ◽  
Laura Mazilu ◽  
Andra-Iulia Suceveanu ◽  
Luminita Matei ◽  
...  
Keyword(s):  
Pulmonary Hypertension ◽  
Young Adulthood ◽  
Primary Pulmonary Hypertension ◽  
Endothelin Receptor ◽  
Vein Thrombosis ◽  
Thromboembolic Pulmonary Hypertension ◽  
History Of ◽  
Recurrent Deep Vein Thrombosis ◽  
Deep Vein ◽  
Phosphodiesterase 5

AbstractWe present a case of severe thromboembolic pulmonary hypertension in a patient with history of recurrent deep vein thrombosis and pulmonary restrictive disease due to pulmonary and vertebral tuberculosis in young adulthood. He was considered not eligible in the National Program for Primary Pulmonary Hypertension, being referred for thoracic surgery, but he was considered unfit for thrombendarterectomy. Despite guidelines, we administered him specific medical therapy (phosphodiesterase-5 inhibitors and endothelin receptor antagonists). His clinical evolution was satisfactory, with increasing effort tolerance and decreasing need for ambulatory oxigenotherapy.

scholarly journals The Silent Era in Australian Cinema

2014 ◽  
Vol 6 (1) ◽  
pp. 88-97
Author(s):  
Irina Anatolyevna Zvegintseva
Keyword(s):  
Film Criticism ◽  
Human Being ◽  
National Cinema ◽  
The Past ◽  
The People ◽  
The Future ◽  
History Of ◽  
Contemporary Cinema ◽  
The Individual ◽  
Silent Era

The article focuses on the first period in the history of Australian cinema. It is well-known that the present is always rooted in the past. This is true of any national cinema, and the Australian one is no exception. This subject is relevant in the light of the fact that, in the first place, the reasons for the contemporary boom in Australian cinema are impossible to understand and analyze unless they are derived from the awareness of the first steps of Australian cinema. It was in the very first years of the existence of Australian cinema that there emerged a special worldview, inherent in the cinematographic messages of this nation, that would later become iconic of Australian cinema: addressing the reality of Australia, love for its wild and beautiful nature and for the people who civilize this severe land. In their works the filmmakers of the Green Continent have almost always unflaggingly introduced two protagonists, an animate one, a manly, daring human being, and an inanimate one, the nature, magnificent, powerful, unexplored... At the same time, there was formed an image of a Hero: a fair, proud man, for whom honor and dignity are closely linked to striving for freedom. A conflict between the Individual and a soulless system is manifested in the early bushranger films and in the contemporary ones alike, now that the films by the Australian filmmakers come out again and again featuring the Individuals attempts at breaking his bondage. The novelty of this research lies in the fact that while the contemporary period of Australian cinema is well-covered in the global film criticism, the past of this national cinema is almost unknown. Considering the interest in the phenomenon of the contemporary cinema of the Green Continent, the author concludes that the global success of the Australian films today is largely linked to the accomplishments of the cinema pioneers, who against tough competition from American and English films, have laid a foundation for the future victories of this special national cinema.

scholarly journals ХРАМ НАУКИ: МОЗАЇКИ М. А. СТОРОЖЕНКА В ІНТЕР’ЄРАХ ІНСТИТУТУ ТЕОРЕТИЧНОЇ ФІЗИКИ ІМЕНІ М. М. БОГОЛЮБОВА НАН УКРАЇНИ У ФЕОФАНІЇ

2020 ◽  
pp. 166-174
Author(s):  
О. А. Тарасенко ◽  
А. А. Тарасенко ◽  
Н. Р. Кубриш
Keyword(s):  
Theoretical Physics ◽  
Decorative Art ◽  
The People ◽  
History Of ◽  
Modern Level ◽  
Artistic Images ◽  
The Individual ◽  
The Temple ◽  
Individual Style

The purpose of the article is to study the history of creation and ideological content of mosaics MykolaAndrievichStorozhenko (1928–2015) in the interior of the Bogolyubov Institute for Theoretical Physics, NAS of Ukraine, Theophany (1969) in the context of Ukrainian and world heritage of monumental art. The study used historical-cultural, comparative, iconographic and iconologic methods. We rely on the theory of "big time" by M. M. Bakhtin, that allows us to consider the mosaic M. A. Storozhenko with the legacy of world art. The significance of the artistic images of the enlighteners as the apostles of spiritual and scientific knowledge – the pillars of the Temple of Science is shown. Artistic-stylistic analysis revealed the features of the embodiment of the idea of scientific and cultural interconnection of generations of Ukrainian scholars-educators by means of monumental art. The importance of the heritage of national and world art in the addition of the individual style of M. A. Storozhenko is studied. The role of ornament as a national code for the embodiment of the idea of the connection between the clan and the people is revealed. The significance of mosaics in the history of monumental art of Ukraine is determined. The philosophical, cultural and historical content of the monumental compositions of M. A. Storozhenko was studied in conjunction with the problems of national self-identification and polystylism of twentieth-century art. The results of the study are necessary to create the history of monumental decorative art of Ukraine at the modern level of art history.

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