scholarly journals Evaluation of medicinal uses, phytochemistry and biological activities of Ehretia cymosa Thonn. (Ehretiaceae)

2021 ◽  
Vol 12 (2) ◽  
pp. 1521-1528
Author(s):  
Alfred Maroyi

Ehretia cymosa Thonn. is a deciduous medium-sized to large tree which occurs naturally from Sierra Leone in West Africa to Eritrea and Kenya in East Africa, and Zimbabwe in southern Africa. This study aims to provide a comprehensive review of medicinal uses, phytochemistry and biological activities of E. cymosa. This review examines the existing literature on the medicinal uses, phytochemistry and biological activities of E. cymosa. This study revealed that the bark, leaf juice, leaves, roots, seeds, stems, twigs and whole plant parts of E. cymosa are mainly used as aphrodisiac, laxative and ethnoveterinary medicines and as traditional medicines for gastro-intestinal problems, wounds, malaria, fever, typhoid, convulsions, epilepsy, toothache and respiratory infections. Phytochemical research revealed that the species is characterized by alkaloids, anthraquinones, essential oils, fatty acids, flavonoids, glycosides, phenolics, proanthocyanidins, pseudotannins, reducing sugars, saponins, steroids, tannins and terpenes. Ethnopharmacological research revealed that the extracts of E. cymosa and phytochemical compounds isolated from the species showed antibacterial, antidiabetic, antihyperglycaemic and antioxidant activities. Ehretia cymosa  should be subjected to detailed phytochemical, pharmacological and toxicological evaluations aimed at correlating its medicinal uses with its phytochemistry and pharmacological properties.

2020 ◽  
Vol 10 (5) ◽  
pp. 190-195
Author(s):  
Alfred Maroyi

Cladostemon kirkii (Oliv.) Pax & Gilg is a shrub or a small tree widely used as traditional medicine in tropical Africa. This study is aimed at evaluating the chemical properties, biological activities and ethnomedicinal uses of C. kirkii. Results of the current study are based on data derived from several online databases such as Scopus, Google Scholar, PubMed and Science Direct, and pre-electronic sources such as scientific publications, books, dissertations, book chapters and journal articles. The articles published between 1960 and 2019 were used in this study. This study revealed that the bark, leaf, root and stem infusion and/or decoction of C. kirkii are mainly used as traditional medicines for boils, colds, gastro-intestinal problems, hypertension, ophthalmia, rheumatism, sexual dysfunction, abdominal pains, sexually transmitted infections, sores and wounds. Phytochemical compounds identified from the species include mearnsitrin, myricitrin, kaempferol-5-rhamnoside, kaempferin, kaempferol 3-gluco-7-rhamnoside, quercetin 3,7-dirhamnoside, quercetin 3-gluco-7-rhamnoside, choline, 3-hydroxyprolinebetaine and tetramethylammonium. Cladostemon kirkii should be subjected to detailed phytochemical, pharmacological and toxicological evaluations aimed at correlating its medicinal uses with its phytochemistry and pharmacological properties.


2020 ◽  
Vol 10 (5) ◽  
pp. 213-222
Author(s):  
Alfred Maroyi

Cissampelos mucronata A. Rich. is a perennial climber widely used as traditional medicine in tropical Africa. This study is aimed at providing a critical review of medicinal uses, phytochemical and pharmacological properties of C. mucronata. Documented information on medicinal uses, phytochemical and pharmacological properties of C. mucronata was collected from several online sources such as Scopus, Google Scholar, PubMed and Science Direct, and pre-electronic sources such as book chapters, books, journal articles and scientific publications obtained from the University library. The articles published between 1962 and 2020 were used in this study. This study revealed that leaves, rhizome, roots and stems, and whole plant parts of C. mucronata are mainly used as traditional medicines for sexually transmitted infections, fever, swellings, headache, respiratory problems, snakebite, malaria, pregnancy problems and gastro-intestinal problems. Phytochemical compounds identified from the species include alkaloids, anthraquinones, flavonoids, glycerine, glycosides, phenolics, reducing sugars, resin, saponins, steroids, tannins and triterpenes. Pharmacological research revealed that C. mucronata extracts and alkaloids isolated from the species have antibacterial, anti-mycobacterial, antifungal, antiplasmodial, antitrypanosomal, anti-ulcer, anti-androgenic, anti-steroidogenic, enzyme tyrosine kinase p56 inhibitory, hypoglycemic, larvicidal, molluscicidal, sedative, tocolytic, uterine relaxant and cytotoxicity activities. There is need for extensive toxicological evaluations of crude extracts and compounds isolated from the species since C. mucronata contains potentially toxic compounds


2020 ◽  
Vol 10 (5) ◽  
pp. 239-246
Author(s):  
Alfred Maroyi

Bolusanthus speciosus (Bolus) Harms is a deciduous and ornamental tree with its different parts used traditionally to treat various diseases. The main aim of this review is to provide an overview and critical analysis of the medicinal uses, phytochemistry, and biological activities of B. speciosus. The information presented in this study was gathered using various databases such as PubMed, Taylor and Francis imprints, Springer, NCBI, Google scholar and Science direct, and review of books, journal articles and other scientific publications kept in the university library. The articles published between 1933 and 2020 were used in this study. The bark, leaf and stem infusion of B. speciosus are mainly used for cleansing blood and as an emetic, and a traditional medicine for abdominal pains, kidney problems, sexually transmitted infections and stomach problems. Phytochemical compounds identified from the leaves, root bark, root wood, seeds and stem bark of B. speciosus include alkaloids, essential oils, flavonoids, phenolics, saponins and tannins. The biological activities exhibited by B. speciosus and the phytochemical compounds isolated from the species include anti-arthritic, antibacterial, antigonococcal, antimycobacterial, antifungal, anti-HIV, anti-inflammatory and antioxidant activities. Future research should focus on toxicological screening, in vivo studies and clinical trials involving the crude extracts and phytochemical compounds isolated from the species.


Author(s):  
Alfred Maroyi

Heteromorpha arborescens is an important medicinal plant species throughout its distributional range in tropical Africa. This study evaluated the botany, medicinal uses, and pharmacological activities of H. arborescens. Literature focusing on the botany, phytochemical, pharmacological, and toxicological properties of H. arborescens were obtained from scientific databases such as SCOPUS, Science Direct, PubMed, SciFinder, Medline, and Google Scholar. Pre-electronic literature sources such as book chapters, books, journal articles, conference papers, and other scientific documents were obtained from the University library. Literature search revealed that H. arborescens is used as an aphrodisiac, as herbal medicine for shortness of breath, intestinal worms, inflammation, pain, respiratory problems, skin infections, headache, fever, and malaria. Pharmacological studies of compounds and H. arborescens extracts revealed anthelmintic, antiarthritic, antibacterial, antifungal, anti-inflammatory, antimycobacterial, antinociceptive, antioxidant, antipeptic ulcer, anti-scabies, antispasmodic, antiviral, cytotoxicity, genotoxicity, and uterotonic activities. More detailed research is needed aimed at assessing phytochemical, pharmacological, and toxicological properties of different plant parts and phytochemical compounds isolated from the species.


2018 ◽  
Vol 7 (1) ◽  
pp. 66-71 ◽  
Author(s):  
Mohd Shahijahan Dar ◽  
◽  
GH. Nabi Joo ◽  
Showkat Ahmad Ganaie ◽  
◽  
...  

Man has used plants since time immemorial to alleviate sufferings and ailments. The present study attempts to explore and document the medicinal plants used against several diseases by the tribal and rural community of Sata Pokhran area of district Pulwama. During the survey from March to September 2017, a total of 28 different plant species belonging to equal number of genera and 16 different families were found to be used as effective remedies. The present study revealed that either whole plant or some plant parts are used to cure different diseases. It was also observed that majority of plant species are used to treat more than one disease and likewise more than one plant species is used to treat a particular disease. The scientific, local and family names of these medicinal plants along with their parts used, mode of administration and ethno medicinal uses are presented in this paper


2021 ◽  
Vol 11 (2) ◽  
pp. 135-140
Author(s):  
S Shanmugam ◽  
C P Muthupandi ◽  
V M Eswaran ◽  
K Rajendran

Most of the people depending on traditional medicine to meet their primary healthcare needs. Documenting the indigenous knowledge through ethnobotanical studies is important for the conservation of biological resources as well as their sustainable utilization. It is also necessary to collect the information about the knowledge of traditional medicines before it is permanently lost. Having all these facts in mind, the present study was carried out to document the plants used as medicine by the people inhabiting around the Vettangudi Water Bird Sanctuary of Sivagangai district in Tamil Nadu, India. The field survey was conducted in two villages situated near to Vettangudi Water Bird Sanctuary. The medicinal uses of 40 angiospermic plant species belonging to 36 genera of 24 families for various diseases and ailments were recorded by this study. The people inhabiting in the study area used 45 herbal therapies prepared from 40 plants to treat 27 different illnesses. Regarding the plant parts used, leaf was the mostly used plant part (51.16%) and extract was found as mostly followed mode (42.28%) to treat a particular disease. Attention should be made on proper exploitation and utilization of these medicinally important plant species. Keywords: Medicinal plants, Vettangudi Water Bird Sanctuary, Sivagangai district, Tamil Nadu.


Author(s):  
Alfred Maroyi

Hilliardiellia aristata is a herbaceous plant species used as traditional medicine in southern Africa. The current investigation is aimed at reviewing the phytochemistry, pharmacological properties and medicinal uses of H. aristata. Results of the current study are based on literature search on pharmacological properties, phytochemistry and medicinal uses of H. aristata using information obtained from several internet sources such as Scopus, Elsevier, SciFinder, Google Scholar, Pubmed, ScienceDirect, BMC and Web of Science. Other sources of information included pre-electronic sources such as journal articles, theses, book chapters, books and other scientific publications obtained from the University library. The current study showed that H. aristata is used as a protective charm, traditional medicine for kidney problems, fever, headache, respiratory infections and malaria. Ethnopharmacological research identified glaucolides, lactones, alkaloids, phenols, tannins, glycosides, terpenoids, saponins, flavonoids and steroids from the aerial parts and leaves of H. aristata. The aerial parts, leaves, roots and whole plant parts of H. aristata exhibited anti-inflammatory, antibacterial, antifungal, antiplasmodial, antiprotozoal, larvicidal and cytotoxicity activities. Hilliardiella aristata should be subjected to detailed phytochemical, pharmacological and toxicological studies.


Author(s):  
Dr. Deepak Chandran

Nature is a unique source of structures of high phytochemical diversity, many of them possessing interesting biological activities and medicinal properties. Phytochemicals ensure safe, eco-friendly and most effective drug for animal use. Veterinarians use these phytochemicals with the knowledge from traditional system and modern pharmacology. High cost of allopathic medicine is one of the major contributing factors in loss of productive livestock and animal productivity. Many plants have been identified which show promising abilities in disease prevention and cure. Phytochemicals can be used either by feeding whole plant parts or by the process of extraction of these chemicals and delivering in concentrated forms. The pharmacological activities of plants are attributed to certain active principles, namely alkaloids, glycosides, fats, oils, tannins, saponins etc. The use of cheap and easily available phytochemicals can thus be made by taking a leaf out of the ethno-veterinary practices. Although the effects of natural remedies may seem slower, the results are sometimes better on the long run especially with respect to chronic diseases. The horizon of phytochemicals has to be explored and exploited to create a “green treatment” protocol to develop an ecofriendly and toxin free production system that is beneficial for existence of both human and animal population in the near future.


2020 ◽  
Vol 11 (4) ◽  
pp. 5876-5885
Author(s):  
Alfred Maroyi

Gardenia ternifolia Schum. & Thonn. is a shrub or small tree widely used as a traditional medicine throughout its distributional range in tropical Africa. Gardenia ternifolia is widespread in tropical Africa, extending from Senegal eastwards to Ethiopia and Kenya, through the Democratic Republic of Congo (DRC) southwards to Namibia, South Africa and Mozambique. This study was aimed at providing a critical review of the medicinal uses, phytochemistry and biological activities of G. ternifolia. Documented information on the medicinal uses, phytochemistry and biological activities of G. ternifolia was collected from several online sources which included Scopus, Google Scholar, PubMed and Science Direct. Additional information was gathered from pre-electronic sources such as book chapters, books, journal articles and scientific publications obtained from the university library. This study showed that the species is widely used as an aphrodisiac and protective charm, and traditional medicine for headache, migraine, respiratory infections, sore eyes, hypertension, diabetes, gastro-intestinal problems, erectile dysfunction, malaria, convulsions and epilepsy. Phytochemical compounds identified from the species include alkaloids, anthocyanins, coumarins, flavonoids, phenols, quinones, saponins, steroids, stereoisomeric neolignans, tannins and terpenoids. Pharmacological research revealed that G. ternifolia extracts and compounds isolated from the species have antibacterial, antiviral, anti-inflammatory, antileishmanial, antioxidant, antiplasmodial, antisickling, antitheilerial, hepatotoxicity, larvicidal and cytotoxicity activities. Future research on G. ternifolia should focus on detailed phytochemical evaluations, including toxicological, in vivo and clinical studies to corroborate the traditional medical applications of the species.


Author(s):  
ANJU BHATNAGAR

Picrorhiza (family Scrophulariace), commonly known as ‘kukti’ is a small perennial herb found in the Himalayan regions of China, Pakistan, India, Bhutan and Nepal at an altitude of 3000-5200 m. Different plant parts and its extract have traditionally been used as a remedy of various ailments such as fever, asthma, jaundice, anemia, abdominal pain, dysentery, cold, stomach problems. Picrorihza has been investigated for its chemical composition and biological activities by various researchers. The major chemical constituents found in this plant were iridoid glycosides, cucurbitacins (triterpenoids) glycosides, phenylethanoid glycosides and phenolics. The Picrorihza has various pharmacological properties, including hepto-protective, antimicrobial, anti-mutagenic, cardio-protective, anti-malarial, anti-diabetic, anti-cancer, anti-inflammatory, anti-ulcer, and neuroprotective and antioxidant activities. A thorough bibliographic investigation was carried out by analyzing worldwide scientific databases including Pub Med, Science Direct, Google Scholar and Wiley online as well as offline sources. The Present review is aimed to provide an updated overview of traditional uses, chemical constituents and biological activities of Picrorihza to explore its therapeutic potentials and to provide bases for future research.


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