scholarly journals Medical-social risk factors of cervical cancer development among women of reproductive age

Cervical cancer is one of the widespread diseases that have a negative impact on the reproductive health. However, medical-social risk factors which provoke this pathology aren't studied sufficiently yet. We have identified the most significant medical-social risk factors of cervical cancer's development and progression based on data analysis of a sociological study. Thus, it was found that cervical cancer can't be associated with predominantly late reproductive age of women in conditions of the Republic of Belarus: most of the patients with this pathology (more than 53%) were under the age of 35 years old. The group of patients suffered from cervical cancer was quite homogeneous in their social status, which was average and relatively stable in a large majority of them (more than 90%), despite employment in various sectors of the national economy. Social functioning of these patients wasn't significantly different from the main population of women in reproductive age. Thus, early sexual activity and random early sexual relations weren't characteristic for the majority of them: 86.1±4.46% (the control group – 87.3±5.51%, the comparison group – 78.2±3.96%) and 83.5±4.72% (the control group – 89.1±4.28%, the comparison group – 75.2±2.36%). Moreover, the married patients of the main group had the most ordered sexual behavior (p<0.01; tau=0.572) which determined the low prevalence of artificial abortions among them, including menstrual cycle regulation (less than 8%). However, the revealed different defects of health-saving behavior in the main group of patients (more than 70%), including an insufficient level of valeological knowledge, the presence of common harmful habits and low medical activity, indicate that there are significant reserves for improvement of the preventive activities of medical stuff in the field of primary medical care for the development of a healthy lifestyle among female population of reproductive age and providing clinical examination among this contingent of females in reproductive age with the purpose of cervical cancer prevention.

2019 ◽  
Vol 5 (4) ◽  
pp. 137-143
Author(s):  
N. Kudaibergenov

The comprehensive assessment of medical and social risk factors and their impact on the health of children working at industrial waste landfills of the Kyrgyz Chemical Metallurgical Plant has presented. Various industrial and environmental factors were covered. To identify signs of environmental pollution by radioactive substances of natural and artificial origin the average values of gamma-radiation power levels have been examined. The hygienic, sociological, medical and statistical research methods are used. During the study, the social-hygienic and living conditions of life and work of children were studied. The selection of respondents conducted by random sampling. The health condition of children living in the region but not working at industrial waste landfills has studied to compare the data of a control group. An assessment of the physical and biological development of children in the experimental and control groups was carried out by measuring somatometric indicators (length and body weight, head circumference), as well as indicators of dynamometry and their external respiration function. The intensive morbidity rates of children have been studied. The article analyzes the impact of medical and social risk factors that adversely affect the health conditions of working children. It describes the various factors of the working environment and the labor process, which form the occupational risk of morbidity. An important part of the study was to assess the situation and identify possible causes that force families to involve children to work at industrial waste landfills.


2017 ◽  
Vol 2 (2) ◽  
pp. 60-65
Author(s):  
GF F Rusanovskaya ◽  
AS S Shprykov ◽  
AV V Pavlunin

Aim - to study the influence of medical and social risk factors on the psychoemotional state and selfesteem of female patients of reproductive age with tuberculosis of the respiratory system. Material and methods. The main group consisted of 93 women aged 18-44 with tuberculosis of the respiratory system who received treatment in one of the anti-tuberculosis institutions of the Nizhny Novgorod region in 2013. The comparison group consisted of 82 almost healthy women of the corresponding age. To assess the psychoemotional state, we carried out a survey using the SAM test method (state of health, activity, mood); to evaluate personality traits - the test «Self-assessment of the personality» by O.I. Motkov. The questionnaire included additional questions of medical and social nature. Results. It was proven that the presence of unfavorable medical and social risk factors in this category of patients causes a decrease in self-evaluation of the positive aspects of the personality, and has a negative impact on the psychoemotional state of patients, causing poor health (lowest evaluated), low activity, bad mood. In the course of long-term treatment, women feel tired and exhausted. Among the medical and social risk factors that have adverse impact on the psychoemotional state and self-esteem of women, the following factors should be highlighted: low level of education, poor financial situation, lack of awareness about prophylaxis of tuberculosis, intense interpersonal relationships in the family, frequent exposure to stress and rueful feelings, irregularity of the prophylactic chest X-ray examinations, violation of the work-rest regime, dietary regimen and quality of nutrition, the history of tubercular contact and incarceration. Conclusion. The results of the research demonstrate the need for developing and implementation of measures of providing psychological assistance to the female patients of reproductive age with active tuberculosis of the respiratory system, as well as new approaches to the prevention of this disease, based on established psychological risk factors for the emergence of tuberculous process and its recurrence.


2019 ◽  
Vol 36 (4) ◽  
pp. 27-32
Author(s):  
R. B. Safarova

Aim. To study the hormonal status in pregnant women of older reproductive age and estimate the influence of administration of medical ozone on the course of pregnancy. Materials and methods. Ninety pregnant women aged 3544 years were examined over the period from 2013 to 2015. They were randomized by their age, social factors, associated gynecological and extragenital diseases. The main group (group I) joined 30 patients, the group of comparison (group II) 30 patients and the control (group III) 30 patients. All the patients underwent clinical and laboratory investigations according to the existing standards of obstetric examination. In the main group, complex treatment included therapy with medical ozone. In the comparison group, a standard medico-preventive therapy by the protocol №05 (20.02.2014 MH of AR) was implemented. In the control group, estrogen indices were studied in dynamics. Results. Pregnant women aged 35 years and older have an unfavorable background of extragenital and gynecological pathology that is confirmed by hormonal background. Conclusions. Planning of pregnancy, timely prevention and correction of clinicolaboratory indices permit to reduce the frequency and severity of pregnancy and delivery complications and improve the perinatal indices among patients of this age group.


2020 ◽  
Vol 17 (3) ◽  
pp. 389-397
Author(s):  
O. V. Kolenko ◽  
E. L. Sorokin ◽  
N. S. Khodzhaev ◽  
N. V. Pomytkina ◽  
G. V. Chizhova ◽  
...  

Purpose. To study the correlation between pregnancy, complicated by preeclampsia and gestational hypertension (GH), and formation of retinal vascular and optic nerve disorders in the late postpartum period.Patients and methods. 231 women with different previous pregnancy variants of pathology. Exclusion criteria — presence of systemic endocrine, autoimmune, rheumatic pathology before pregnancy; bad habits. Four groups were formed. 1st main group: pregnancy with GH. 2nd main group: pregnancy with preeclampsia. 1st comparison group: pregnancy on the background of pre-existing hypertension, without proteinuria. 2nd comparison group: edema and/or proteinuria during pregnancy, without hypertension. The control group — physiological process of pregnancy. Period of ophthalmological examination after pregnancy is 6–12 years.Results. Development of various vascular and ischemic disorders of posterior eye segment occurred in 70 women (30.3 %). The periods of their formation after previous pregnancy varied from 3 to 11 years. Their frequency in the 1st and 2nd main groups was statistically significantly higher. The most common were retinal vein occlusion and post-thrombotic retinopathy. The negative outcomes of transferred GH and preeclampsia are no eliminated with delivery and can manifest next years and even decades after it.Conclusion. Нigh risk factors for development of vascular and ischemic disorders of posterior eye segment are transferred preeclampsia, especially with its early onset (20–24 weeks), or premature birth (26–28 weeks); pregnancy, complicated by GH. The risk of developing this eye pathology is highest in women aged 38–40 years and over. 


2020 ◽  
Vol 12 (3) ◽  
pp. 46-50
Author(s):  
V. I. Sergevnin ◽  
O. V. Tukacheva ◽  
M. V. Kokorina ◽  
M. G. Мenshikova

Objective. Assessment of tuberculosis (TB) infection conditions for HIV-infected people.Materials and methods. Еpidemiological survey of 38 epidemic foci of HIV-associated tuberculosis, 28 foci of tuberculosis without HIV infection and 20 foci in which the diagnosis of tuberculosis wasn`t confirmed (control-group) were conducted.Results and its discussion. As it turns out that in the most cases of the development of HIV-associated TB, the primary diagnosis of HIV infection preceded the primary diagnosis of tuberculosis. According to the results of the case-control analytical epidemiological study, such risk factors of HIV-infected tuberculosis as lack of family, higher education and regular job, the fact of deprivation of liberty and drug users (as a reflection of the low social status of patients), as well as contact with tuberculosis patient were identified. Risk factors for mycobacteria infection in people without HIV infection were only the lack of family and contact with tuberculosis patients.


Author(s):  
Yu. A. Orlova

Endometrioid disease today is ranking one of the leading positions in the structure of gynaecological diseases. The prevalence of this endometrioid disease reaches 10% among the female population and up to 70% among women of child-bearing age. Ambiguity in terms of the aetiology, pathogenesis, and predictors of the disease impedes the accurate and quick diagnosis and proper management of this disease. The aim of this study is to analyze and to compare symptomatic and anamnestic data presented by women who have with endometrioid disease and have no it, and to identify and analyze predictors and consequences of endometrioid disease. The study examined 80 women of reproductive age. The main group involved 50 women with endometrioid disease; the control group included 30 women without signs of endometrioid disease. All participants underwent clinical examination and were interviewed about symptoms, family history, menstrual function, past gynaecological, reproductive, infectious (infectious diseases, transferred in childhood), somatic diseases. The information about the presence of psychological and physical overstrain in women of both groups was obtained (subjectively from the words of women) and then assessed. Contributory factors or predictors in the development and progression of endometrioid disease are as follows: an increased number of occupational hazards (22.6% versus 0%, respectively, p = 0.03) among working women with endometrioid disease; regular psychological overstrain, which can result from endometrioid disease on the one hand, and, contribute to its progression, on the other (70% versus 43.3%; p = 0.03); the presence of the 0 blood type (40% versus 16.7%; p = 0.029), the presence of chronic inflammation of the uterine appendages in the past (60% versus 36.6%; p = 0.04); human papilloma virus in past or present medical history (14% versus 0%; p = 0.04). The possible consequences of endometrioid disease include somatic pathology prevailing in 1.3 times. Special attention should be paid to the average number of gastro-intestinal diseases in the women of main and control groups: 1.34 ± 1.3 versus 0.77 ± 1.1, respectively; p = 0.04. The prevalence of diseases of urinary system is as follows: 0.66 ± 0.68 versus 0.33 ± 0.54, respectively; p = 0.04. The menstruations are described as irregular, heaving bleedings often with dark brown discharge before menstruation, pain during menstruation. The study revealed a large percentage of infertility in patients with endometrioid disease (60% versus 33.3%, respectively; p = 0.02), reduced reproductive potential in general (the average number of pregnancies per woman in the control group is 1.9 times higher). It should be noted that 14 (28%) women of the main group have relapse of endometrioid disease in the form of repeated cysts after conservative and / or surgical treatment. Thus, endometrioid disease was detected for the first time in 36 (72%) women of the main group. The information obtained in the study can be helpful for medical practitioners as it deepens knowledge about possible predictor factors, premorbid background and the consequences of endometrioid disease, and, thus, will serve in customized management of such patients.


2021 ◽  
Vol 7 (3) ◽  
pp. 177-182
Author(s):  
A. Tabysheva ◽  
G. Maimerova ◽  
I. Shaiderova

The article presents data on social the risk factors for the birth of premature newborns who were on inpatient treatment in the perinatal center of Osh (Kyrgyz Republic). The study group included 93 children, the first group consisted of premature newborns with ENMT 31 (25.2%), the second group — 62 (50.4%) newborns with ONMT, the comparison group included 30 (24.4%) premature newborns.


2021 ◽  
Author(s):  
MI Timerzyanov ◽  
OA Ilina ◽  
EA Dubrvina ◽  
OYu Milushkina ◽  
DE Vasilev

The objective of the study was to develop and implement the system of hygienic measures eliminating (mitigating) the impact of risk factors in the work of forensic scientists and to estimate effectiveness of these measures and the program aimed at improvement of employment terms for forensic scientists [1, 2]. Forensic scientists were compared to a control group of other doctors. The following researches were carried out: survey of 303 forensic scientists, analysis of their employment terms based on employment terms special evaluation (2,736 materials of employment terms special evaluation), examination of forensic scientists’ health compared to other doctors by analyzing medical examination results (309 health records). Protection and promotion of working population’s health is the state priority. Its purpose is to preserve labor potential and create conditions for economic development of the country. Medical workers are exposed to a combined, complex, and associated effect of working environment conditions and parameters [3, 4]. Industrial and social factors can result in a rising incidence, reduction in life expectancy, ill health and medical staff performance increment, and require preventive measures. Those working for forensic expert organizations constitute a special population due to a large number of professional, medical and organizational, and social risk factors [5].


2017 ◽  
pp. 85-88
Author(s):  
O.I. Ostapenko ◽  
◽  
V.P. Kvashenko ◽  
I.K. Akimova ◽  
I.N. Nosova ◽  
...  

The objective: the study of immunomodulatory effects of a probiotic, which contains lyophilized Lactobacillus (Lactobacillus rhamnosus) – 13 mg (2,0ґ109 CFU) and lyophilized bifidobacteria (Bifidobacterium lactis) – 4 mg (2,0ґ109 CFU) the level of serum immunoglobulin IgA as a marker of local immunity in the plasma of women of reproductive age with the violation of the biocenosis of the vagina. Patients and methods. The study involved 86 patients of reproductive age with the violation of the vaginal biocenosis, which were divided into two groups according to received treatment. A survey was conducted for all patients in both groups: determine the level of serum IgA, measuring pH of vaginal environment and the quantification of lactobacilli and pathogenic flora with the help of test-system «Florotsenoz» before treatment and in 6 weeks after treatment. The state of vaginal microbiocenosis in both groups before treatment was homogeneous. Patients in both groups as therapy at the first stage of treatment received, if necessary antimicrobial therapy depending on the selected flora. In the second stage (restoration of microflora) patient of the main group received systemic probiotic combined with a complex prebiotic local action, patients in the control group, the probiotic localy in the form of the vaginal candles or tablets. Results. The research stated the increasing level of serum IgA in blood plasma of patients of the main group compared to control group at 20%, normalizing the pH of the vaginal environment in the main group in 94% of cases, which indicates an increase of immunity in mucosal. Conclusion. The inclusion of the systemic probiotic in the scheme of treatment of disorders of biocenosis of the vagina system enhances the increasing of immunity of the mucous membranes, and the vaginal tablets prebiotic of local action restores the own normal microflora of the vagina. Key words: serum immunoglobulin A, local immunity, vaginal dysbiosis, probiotics, prebiotics, vaginal microbiocenosis, the pH of the vaginal environment.


2017 ◽  
pp. 19-24
Author(s):  
O.V. Grishchenko ◽  
◽  
V.V. Bobrytska ◽  

The objective: To evaluate the clinical efficacy and safety of Enoxaparin-Pharmex for the prevention of thrombotic complications (pulmonary embolism) in the postoperative period in patients with moderate risk of these complications. Patients and methods. The study included 50 women after a caesarean section had an average degree of risk of pulmonary embolism. Patients were divided into the main group (n=25) and control group (n=25) in accordance with the treatment: patients of the main group received postoperative Еnoxaparin- Pharmex, group comparisons enoxaparin sodium (brand foreign manufacturer’s). Patients in both groups received the drug at a dose of 20 mg for 5 days, 1 time per day subcutaneously. Results. The research data analysis showed identity results of hemostasiogram of patients in the main group and the comparison group, no side effects after treatment in both groups. Conclusion. The clinical studies suggest the drug Enoxaparin-Pharmex is effective, safe LMWH, which can be used to prevent troboembolic complications, including post-operative treatment in obstetric practice. Spectrum of Enoxaparin-Pharmex can be extended to the prevention and treatment of thromboembolic conditions of varying severity with appropriate doses of the drug. Key words: Enoxaparin-Pharmex, prevention of pulmonary embolism.


Sign in / Sign up

Export Citation Format

Share Document