Comparative study of inj. Rocuronium with priming dose and inj. Rocuronium without priming with respect to onset, time of intubation and intubating conditions in patients undergoing general anaesthesia

2021 ◽  
Vol 19 (2) ◽  
pp. 39-43
Author(s):  
Sachin Swami ◽  
Keyword(s):  
General Anaesthesia ◽  
Randomized Study ◽  
Age Groups ◽  
Onset Time ◽  
Control Group ◽  
P Value ◽  
Priming Dose ◽  
Intubating Conditions ◽  
Significant Difference ◽  
The Difference

Background: Rocuronium is fastest among non-depolarizing muscle relaxants ,but still it produces appropriate intubating conditions comparable to succinylcholine, in >90 seconds on administering 2 × ED95 dose as a bolus dose. In present study we compared the effect of inj. Rocuronium with priming dose and inj. Rocuronium without priming on intubating conditions and onset time of intubation with respect to rocuronium as bolus. Material and Methods: Present study was single-center, prospective, randomized study, conducted in patients of age groups from 18-60 years of either sex , 40-60 kgs weight, ASA grades I and II, undergoing surgeries under general anaesthesia and given valid written consent for participation. The patients were randomly allocated into 2 groups of 30 patients each as Group C (control group) and Group P (priming group). Results: Overall, 60 patients were studied in age group of 18 to 60 years, 30 patients in each group C and group P. we compared mean age, weight, gender and ASA grade between group C and group P and difference was statistically not significant (p value >0.05). We compared mean HR, mean MAP and mean SPO2 preoperatively baseline, at induction, at intubation, mean HR at 1 minute after intubation and mean HR at 5 minute after intubation between group C and group P, the difference between two groups was statistically insignificant. (P value >.05) In group C, out of 30 patients ,17 patients were having score 9 while 12 patients were having score 8, while 1 patient had score 7 which was comparable with the group P in which out of 30 patients ,18 were having score 9,while 11 patients were having score 8 and 1 patient was of score 7,so in both groups most of the patients (96.67% in each group) had excellent intubating condition, and the groups were comparable as statistically no significant difference was noted. In group C mean Onset Time of Intubation was 92.33± 6.26 seconds, while in group P it was 56± 6.75 seconds, so the difference between the groups on the basis of OTI was statistically highly significant. (P value 0.0001) Conclusion: Rocuronium with priming would be an excellent alternative to succinylcholine, whenever fast induction will be needed. Intubating conditions were good to excellent and comparable in both rocuronium with priming and without priming. NMT monitoring is a useful tool for indicating the clinically acceptable paralysis.

scholarly journals TO COMPARE THE TOXICITY PROFILE OF ACCELERATED RADIOTHERAPY (SIX FRACTIONS PER WEEK) WITH CONCOMITANT CHEMO-RADIOTHERAPY IN LOCALLY ADVANCED HEAD AND NECK CANCER

2019 ◽  
Vol 3 (11) ◽  
Author(s):  
Vikrant Kaushal ◽  
Amit Rana ◽  
Manoj Gupta ◽  
Rajeev Seam ◽  
Manish Gupta
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Neck Cancer ◽  
Randomized Study ◽  
Locally Advanced ◽  
Medical Science ◽  
Hematological Toxicity ◽  
P Value ◽  
Significant Difference ◽  
The Difference

Background: Head and neck malignancies are common among males in India. The age adjusted incidence rate of head and neck cancer in India in males is 16.4/100,000 and in females it is 8.8/100,000.In All India Institute of Medical Science head and neck cancer represents 25% of all malignancies registered Methods: This prospective randomized study was conducted in the Department of Radiation Therapy & Oncology, Regional Cancer Centre, IGMC, Shimla and patients were enrolled for a period of one year, from July 2012 to July 2013.It included all the eligible, previously untreated patients of squamous cell carcinoma of Head and Neck with histologically confirmed diagnosis and no evidence of distant metastasis. The sites included were oro-pharynx, hypo-pharynx and larynx with stages III, IV A and IV B. Results: Grade 3 and grade 4 skin toxicities were higher in CRT arm but without statistically significant difference from that in ART arm. G3 & G4 mucositis was higher in the Concomitant CRT arm however the difference was not statistically significant. G2 and G3 Laryngeal Toxicities were higher in Concomitant CRT arm as compared to Accelerated arm but the difference was not statistically significant. G2 & G3 haematological toxicities were significantly (combined p value = 0.002) higher in the concomitant CRT arm (32.4%) as compared to Accelerated RT arm (2.9%). Only one patient in accelerated arm had any hematological toxicity. Conclusion: Higher peak incidence of toxicities was seen in concomitant CRT arm as compared to accelerated arm. Keywords: Toxocity, six fraction, chemoradiation, Local control

scholarly journals PIJAT KOMBINASI ENDORFIN OKSITOSIN MEMPENGARUHI PRODUKSI ASI PADA IBU POST OPERASI SECTIO CAESAREA

2020 ◽  
Vol 5 (1) ◽  
pp. 51
Author(s):  
Nursari Abdul Syukur ◽  
Endah Wahyutri ◽  
Erma Putri
Keyword(s):  
Breast Milk ◽  
Milk Production ◽  
Sectio Caesarea ◽  
Control Group ◽  
P Value ◽  
Control Group Design ◽  
Breast Milk Production ◽  
Significant Difference ◽  
Quasi Experimental ◽  
The Difference

Background: Breast milk spending is a very complex interaction between mechanics, nerves, and hormons. The decrease and production of breast milk production in the first days after delivery can be caused by a lack of stimulation of prolactin and oxytocin hormons. Caesarea section does not allow the mother to breastfeed her infant more flexibly, with adaptation to the pain, so she should be able to support the health worker thoroughly about the lactation process. Purpose: to know the difference of endorphin, oxytocin and combination effect on breast milk production in Postoperative section of caesarea section. Research design: quasi experimental design type post test only non equivalent control group design. The population in this study were all postoperative mothers caesarea section, 10 samples for each treatment. Group 1 : endorphin massage, group 2 (control) : the oxytocin massage, and group 3 : the combine massage. Results: Combination massage is the best method to produce the highest amount of ASI because the largest Sig p value is (1,000) where the level is significant <0.05. So H0 this study was rejected means that there is a significant difference between the production of breast milk from the combination massage compared with the two massage done separately. Conclusion: It is expected during childbirth the midwife can develop and implement independent non-pharmacological midwife actions to help increase milk production

scholarly journals Perbedaan Kadar Hemoglobin dan Hematokrit Bayi Baru Lahir Akibat Perbedaan Waktu Penjepitan Tali Pusat

2016 ◽  
Vol 5 (1) ◽  
Author(s):  
Nuriah Arma ◽  
Yanwirasti Ariadi ◽  
Lisma Evareny
Keyword(s):  
Control Group ◽  
P Value ◽  
Hematocrit Level ◽  
Control Group Design ◽  
Group Design ◽  
Cord Clamping ◽  
Significant Difference ◽  
Post Test ◽  
The Difference ◽  
First Year Of Life

AbstrakBayi baru lahir memiliki 80 ml darah dari plasenta pada 1 menit setelah kelahiran dan 100 ml pada 3 menit setelah lahir, volume ini akan memasok 40-50 mg/kg ekstra besi untuk memiliki 75 mg/kg besi tubuh bayi yang cukup bulan yang dapat mencegah kekurangan zat besi pada tahun pertama kehidupan. Oleh karena itu pemotongan tali pusat yang terlalu cepat setelah persalinan akan mengurangi kandungan besi sekitar 15-30%, sedangkan bila ditunda 3 menit dapat menambah volume sel darah merah sekitar 58%. Tujuan penelitian ini adalah untuk membuktikan adanya perbedaan kadar Hb (hemoglobin) dan Ht (hematokrit) akibat perbedaan waktu penjepitan tali pusat. Penelitian ini dilakukan di tempat Bidan Praktek Mandiri Kota Padang. Jenis penelitian eksperimental dengan post-test only controll group design. Pengambilan sampel secara consecutive sampling sampai tercapai jumlah 36 bayi yang terbagi atas 18 bayi baru lahir pada tiap kelompok. Data dianalisis dengan uji t. Hasil penelitian didapatkan rerata kadar Hb dan Ht pada kelompok penjepitan 3 menit setelah lahir lebih tinggi daripada penjepitan 1 menit. Terdapat perbedaan kadar Hb yang bermakna antara kelompok penjepitan 3 menit setelah lahir daripada 1 menit dengan nilai P=0,004.  Ada terdapat perbedaan Ht yang bermakna antara kelompok penjepitan 3 menit dan 1 menit dengan nilai P=0,001. Kesimpulan penelitian ini ialah kadar Hb dan Ht lebih baik pada penjepitan tali pusat ditunda 3 menit setelah lahir dibandingkan dengan penjepitan 1 menit setelah lahir.Kata kunci: hemoglobin, hematokrit, penjepitan tali pusat AbstractThe newborns contain 80 ml of blood from the placenta in 1 minute after birth and 100 ml in 3 minute after birth. This volume supply 40 to 50 mg/kg of extra iron to have 75 mg/kg of body iron baby full-term that can prevent iron deficiency in the first year of life. Therefore, cutting the umbilical cord too soon after birth will reduce the iron of content about 15 to 30%, whereas when delayed 3 minute its can increase the volume red blood cells about 58%. The objective of this study was to prove the difference of hemoglobin and hematocrit level between 3 minutes and 1 minute cord clamping.  Experimental research was conducted with post-test only control group design of 36 newborns. Data were analyzed by t-test. The result of this study showed that the mean of hemoglobin and hematocrit level in 3 minutes of clamp are higher  than 1 minute of clamp.There was a significant difference of hemoglobin level between 3 minutes cord clamping group and 1 minute cord clamping group with p value is 0.004. There was also a significant difference of hematocrit level between 3 minutes cord clamping group and 1 minute cord clamping group with p value is 0.001. The conclusion is the hemoglobin and hematocrit level are better in cord clamping delayed in 3 minutes after birth than clamping in 1 minute after birth. Keywords: hemoglobin, hematocrit, cord clamping

Comparison of Two Muscle Relaxants for Tracheal Intubation in Patients Undergoing Surgery at Goa Medical College and Hospital

2021 ◽  
Vol 8 (33) ◽  
pp. 3116-3122
Author(s):  
Anisha Deulker ◽  
Rohini Bhat Pai ◽  
Shaila Kamat ◽  
Eufemia Dias
Keyword(s):  
Adverse Effects ◽  
Onset Time ◽  
Neuromuscular Blocking ◽  
Muscle Relaxants ◽  
Neuromuscular Blocking Agents ◽  
P Value ◽  
Blocking Agents ◽  
Intubating Conditions ◽  
Anaphylactoid Reactions ◽  
The Difference

BACKGROUND Cisatracurium and atracurium are intermediate acting muscle relaxants which do not depend on renal or hepatic metabolism for elimination since they undergo Hofmann elimination. Despite the advantages of cisatracurium such as minimal effects on the cardiovascular system, no accumulative effects, no metabolite toxicity, and metabolic product has no neuromuscular blocking effects, due to slow onset and unsatisfactory intubating conditions, the use of cisatracurium is limited compared with those seen with equipotent doses of other neuromuscular blocking agents. This study was undertaken to find onset time and intubating conditions with 3 × ED95 doses of atracurium versus cisatracurium. METHODS ASA grade 1 or 2 patients, (N = 220) were randomly allocated into 2 groups to receive equipotent doses of either atracurium or cisatracurium. Intubating conditions were assessed using Cooper et al scale and neuromuscular monitoring done using TOF Watch SX. Haemodynamic responses and any adverse effects were noted. RESULTS The onset time was 167.36 ± 75.41 seconds (2.78 ± 1.25 minutes) in atracurium group whereas in cisatracurium group, onset time was 249.26 ± 75.90 seconds (4.15 ± 1.26) and the difference was statistically significant with p value of < 0.001. The difference in intubating conditions between the groups was statistically insignificant. However, atracurium produced a higher incidence of clinically acceptable conditions (excellent in 94.4 %) than cisatracurium (excellent in 87.3 %). The incidence of adverse effects such as erythema, flushing and bronchospasm was greater in Atracurium group though hypotension was observed in both groups. CONCLUSIONS Onset time and intubating conditions are significantly better with equipotent doses of atracurium compared to cisatracurium. But atracurium is associated with higher incidence of adverse effects such as erythema, flushing and bronchospasm, though the potential of cisatracurium to cause anaphylactoid reactions cannot be ignored. KEYWORDS Cisatracurium, Atracurium, Muscle Relaxants, Neuromuscular Blocking Agents, Erythema, Flushing, Bronchospasm, Hypotension, Anaphylactoid Reactions

Pseudonormokalemia in Patients with Thrombocytosis.

Blood ◽  
2006 ◽  
Vol 108 (11) ◽  
pp. 3964-3964
Author(s):  
Amir S. Steinberg ◽  
Raimonda Goldman ◽  
Randy L. Levine ◽  
Georgia Panagopoulos ◽  
Marvin C. Cooper
Keyword(s):  
Platelet Count ◽  
Serum Potassium ◽  
Interim Analysis ◽  
Plasma Potassium ◽  
Normal Serum ◽  
Control Group ◽  
P Value ◽  
Significant Difference ◽  
The Mean ◽  
The Difference

Abstract Introduction: Pseudohyperkalemia represents an artificial elevation in serum potassium concentration. It is well described that patients with thrombocytosis may have elevated serum but normal plasma potassium. The difference between serum and plasma potassium is felt to be due to potassium release from platelets during clotting. We propose to prove that a similar mechanism will lead to a "pseudonormokalemia," where serum potassium appears to be in the normal range (3.5–5.0 MEq/L) despite below-normal levels in the plasma(&lt;3.5 MEq/L). Method: This is an interim analysis of a prospective, IRB-approved planned comparison of 146 patients. We compared 36 thrombocytosis patients (platelets&gt;500,000/uL) to 36 control patients (platelets&lt;500,000/uL). Patients were identified from a list of lab results generated by a computer search and serum and plasma potassium and CBC were then drawn concomitantly. The two groups were compared using either the t-test or the Mann-Whitney U test depending on the distribution of the variables. A p &lt;.05 was considered a priori to indicate statistical significance. Results: There was no statistically significant difference in sex distribution or age between the two groups. The average platelet count was 643,190/uL in the thrombocytosis group (SD 134,426 uL) and 280,220/uL (SD 106,217 uL) in the control group with a p value &lt;0.001. While the serum potassium was noted to be significantly different between the two groups, the plasma potassium was not (see table). This was reflected in the difference between the serum and plasma potassium in the two groups. The thrombocytosis group was noted to have a difference between serum and plasma potassium of .52 MEq/L (SD .32 MEq/L) while the control group had a difference of .18 MEq/L (SD .23 MEq/L). The thrombocytosis group had 14 cases in which the difference between serum and plasma potassium was over 0.5 MEq/L whereas the control group had none. Conclusion: In this study, patients with thrombocytosis had higher mean serum potassium levels than the control group but similar mean plasma potassium levels. The mean difference between serum and plasma potassium (Delta) exceeded 0.5 MEq/L in the thrombocytosis arm and there was a statistically significant difference in the Delta values between the two groups. The mean platelet volume (MPV) of the thrombocytosis group was smaller than that of the control group. This indicates that the elevation in serum potassium in the thrombocytosis group cannot be attributed to the actual size of the platelets but rather to the number of platelets involved. Patients with thrombocytosis and normal serum potassium may actually be hypokalemic as this study demonstrates. As we continue to evaluate patients, we believe this difference will become more demonstratable. On interim analysis, our study suggests that in patients with thrombocytosis and normal serum potassium, plasma potassium should be considered along with routine labs. Group Comparison Values (N=36) Thrombocytosis Group-Platelets&gt;500,000/uL Control Group-Platelets&lt;500,000/uL p value Age 60.33 yrs 57.53 yrs p =.50 Serum K+ 4.43 MEq/L 4.15 MEq/L &lt;.001 Plasma K+ 3.91 MEq/L 3.97 MEq/L p =.54 Mean Delta between Serum and Plasma K+ .52 MEq/L (SD .32) .18 MEq/L (SD .23) &lt;0.001 Platelet Count 643.19 X103/uL 280.22X103/uL &lt;0.001 MPV 7.27 fl 8.24 fl &lt;0.001 WBC 12.05 mm3 9.98 mm3 p =.16

scholarly journals INTERVENSI KADER DALAM MENDUKUNG PROGRAM PEMBERIAN OBAT MASSAL PENCEGAHAN (POMP) FILARIASIS DI KECAMATAN CIBEUREUM DAN CIBINGBIN, KABUPATEN KUNINGAN, PROVINSI JAWA BARAT

2018 ◽  
Vol 17 (1) ◽  
pp. 31-40
Author(s):  
Joni Hendri ◽  
Mara Ipa ◽  
Aryo Ginanjar ◽  
Yuneu Yuliasih ◽  
Endang Puji Astuti
Keyword(s):  
T Test ◽  
Control Group ◽  
P Value ◽  
Attitude And Practice ◽  
Significant Difference ◽  
Post Test ◽  
Quasi Experimental ◽  
The Difference ◽  
Knowledge Attitude And Practice ◽  
Paired T Test

ABSTRACT The filariasis mass drug administration (MDA) program is one of the strategies to eliminate lymphatic filariasis. First round coverage in Kuningan Regency was 85.4%, but only 50% of sub-districts have reached the target. The aim of this research was to determine the improvement of knowledge, attitude, and practice (KAP) of health cadres through intervention to increase the filariasis MDA coverage in Kuningan Regency. A quasi-experimental research was conducted in Cibeureum and Cibingbin Sub-District of Kuningan Regency using pretest-posttest design from May to October 2016. Selected subjects of this research were 32 health cadres who were given intervention in the form of workshop utilizing leaflets, handbooks, and video. The difference is treatment group was taught about filariasis related materials by an expert but the control group was not. Data were analyzed with paired t-test. The result showed that there was a significant difference between pre-test and post-test in terms of KAP in both groups with p-value of 0,000, but there was no difference in value between the two groups. Thus, the study concluded that training on cadres with a filariasis expert could be an effective strategy as to increase MDA coverage. Keywords: Intervention, filariasis MDA, knowledge, cadre   ABSTRAK Pemberian Obat Massal Pencegahan (POMP) merupakan salah satu strategi eliminasi filariasis di Indonesia. Hasil cakupan POMP putaran pertama di Kabupaten Kuningan mencapai 85,4% dari total target penduduk, namun hanya 50% kecamatan yang mencapainya. Tujuan penelitian ini adalah untuk mengetahui peningkatan pengetahuan, sikap dan perilaku kader setelah dilakukan intervensi dalam rangka meningkatkan cakupan pengobatan filariasis di Kabupaten Kuningan. Penelitian dilakukan di Kecamatan Cibeureum dan Cibingbin, Kabupaten Kuningan pada bulan Mei - Oktober tahun 2016 dengan eksperimen semu menggunakan desain  pretest-posttest control group. Sampel penelitian adalah 32 kader yang diberi intervensi berupa pelatihan dengan media cetak  dan video. Perbedaan antara kelompok intervensi dengan kontrol adalah bahwa kelompok intervensi diajarkan materi terkait filariasis oleh seorang ahli dan kelompok kontrol tidak diberikan pelatihan. Data dianalisis menggunakan paired t-test. Hasil penelitian menunjukkan adanya perbedaan pada skor nilai pretest-posttest pengetahuan, sikap, dan perilaku pada masing-masing kedua kelompok dengan hubungan bermakna (p-value 0,000), tetapi tidak terdapat perbedaan nilai pretest-posttest antara kelompok intervensi dan kontrol. Hal ini berarti tidak ada perbedaan yang signifikan antara kelompok intervensi dan kontrol. Kesimpulannya bahwa pelatihan pada kader menggunakan media cetak dan video dengan narasumber pakar filariasis merupakan salah satu strategi efektif untuk meningkatkan cakupan pengobatan POMP filariasis. Kata kunci: Intervensi, POMP, pengetahuan, kader

Randomized study of darbepoetin alfa as modifier of radiotherapy in patients with primary squamous cell carcinoma of the head and neck (HNSCC): Final outcome of the DAHANCA 10 trial

2009 ◽  
Vol 27 (15_suppl) ◽  
pp. 6007-6007 ◽  
Author(s):  
J. Overgaard ◽  
C. M. Hoff ◽  
H. S. Hansen ◽  
L. Specht ◽  
M. Overgaard ◽  
...  
Keyword(s):  
Interim Analysis ◽  
Randomized Study ◽  
Disease Free Survival ◽  
Experimental Treatment ◽  
Control Group ◽  
Tumor Control ◽  
Tumor Site ◽  
Significant Difference ◽  
The Difference ◽  
N Staging

6007 Background: The study aimed to evaluate if correction of low hemoglobin (Hb) levels by means of the erythropoietin stimulating agent: darbepoetin alpha (Aranesp) during radiotherapy (RT) improves outcome in patients with HNSCC. Following a planned interim analysis which showed inferiority of the experimental treatment, the trial was stopped in November 2006. Methods: Pts with HNSCC eligible for primary RT alone and with Hb values below 14.0 g/dl were randomized to receive Aranesp together with accelerated fractionated RT. Pts. were stratified according to gender, T and N staging, tumor site, and institution. Aranesp was given subcutaneously in a dose of 150 micrograms weekly during RT, or stopped earlier if the Hb exceeded 15.5 g/dl. Results: In total, 522 patients (of a planned intake of 600) were included at the time of the interim analysis. Of these 514 pts were eligible for analysis (255 pts treated with Aranesp and 259 pts in the control group) with a median follow up of 49 months. Among these, 201 developed a loco-regional failure (primary endpoint). There have been 238 deaths of which 176 are due to HNSCC. The patients were evenly distributed according to the stratification parameters (gender, T and N staging, tumor site, institution).Aranesp resulted in the expected increase in Hb in more than 81% of the patients. The compliance to Aranesp was good with no significant difference in serious (cardiovascular) adverse events (3% vs. 1%). Overall, the results showed a poorer outcome in 5-year loco-regional control (59% vs. 68% (p = 0.04, RR: 1.47 [1.14–1.94]) for the Aranesp vs. control arm. This was also seen for the endpoint of disease-free survival (37% vs. 47%, p = 0.02, RR: 1.32 [1.04–1.68]), whereas there was no significant difference in overall survival (40% vs. 51%, p = 0.16, RR: 1.20 [0.93–1.55]). There were no differences in radiation related morbidity. All univariate analyses were confirmed in a multivariate setting. Conclusions: Correction of the Hb level with Aranesp in patients with HNSCC resulted in a significantly poorer tumor control after radiotherapy. The treatment principle was abandoned and the difference in outcome is being subjected to further examination. No significant financial relationships to disclose.

scholarly journals Efficacy of magnesium sulfate as an adjuvant to rocuronium in general anaesthesia: a meta-analysis

2021 ◽  
Vol 49 (7) ◽  
pp. 030006052110277
Author(s):  
Haiyan Sun ◽  
Tao Jin ◽  
Xiping Wu ◽  
Lei Yang ◽  
Yunxia Zuo ◽  
...  
Keyword(s):  
Magnesium Sulfate ◽  
General Anaesthesia ◽  
Neuromuscular Block ◽  
Meta Analysis ◽  
Onset Time ◽  
Biomedical Literature ◽  
Cochrane Library ◽  
Control Group ◽  
China National Knowledge Infrastructure ◽  
Significant Difference

Objective Magnesium sulfate is considered to be an effective adjuvant to rocuronium in general anaesthesia. We conducted a meta-analysis to clarify its efficacy. Methods We searched the PubMed, Embase, Web of Science, Cochrane Library, WanFang, Chinese Biomedical Literature, and China National Knowledge Infrastructure databases for randomized controlled trials (RCTs) of magnesium sulfate as an adjuvant to rocuronium from the start of the database establishment until May 2020. Results Eleven RCTs were analysed. The pooled meta-analysis showed that using magnesium sulfate as an adjuvant significantly shortened the onset time and prolonged the clinical duration of neuromuscular blockade by rocuronium compared with the control group without magnesium sulfate. However, there was no significant difference in recovery index of neuromuscular block between the magnesium and control groups. Furthermore, magnesium sulfate significantly increased the rates of excellent and clinically acceptable intubation conditions. Conclusion Adding magnesium sulfate to rocuronium during general anaesthesia can alter the neuromuscular parameters, including shortening the anaesthesia-onset time and prolonging the clinical duration, without significantly increasing the recovery time. Pretreatment with magnesium sulfate may also improve intubation conditions during general anaesthesia.

Can Acupuncture Reduce the Induction Time of a Local Anaesthetic? - a Pilot Study

2003 ◽  
Vol 21 (3) ◽  
pp. 92-99 ◽  
Author(s):  
Palle Rosted ◽  
Mads Bundgaard
Keyword(s):  
Pilot Study ◽  
Local Anaesthetic ◽  
Standard Treatment ◽  
Dental Treatment ◽  
Onset Time ◽  
Acupuncture Group ◽  
Control Group ◽  
Lower Lip ◽  
Significant Difference ◽  
The Difference

We report on a pilot study we undertook to investigate if segmental acupuncture treatment, given two minutes prior to a regional inferior dental block (ID) with Prilocaine Hydrochloride, would reduce the onset time of a local anaesthetic. Thirty healthy people, who needed a regional inferior dental block (ID) as part of dental treatment in the lower jaw, were randomly allocated to three groups. They received segmental acupuncture, heterosegmental superficial acupuncture, or standard treatment (regional inferior dental block) without acupuncture. In the segmental acupuncture group, acupuncture was given within the innervation of the trigeminal nerve. The needles were left in for two minutes, followed by a regional inferior dental block (ID). In the second group, acupuncture needles were inserted superficially in extra-segmental points and left in for two minutes without stimulation, followed by the regional inferior dental block. A control group received standard treatment only, of a regional inferior dental block. The concept ‘pain free for dental work’ was defined as ‘patients reporting pins and needles in the lower lip’ and measured by a drilling test. Patients who reported no pain during the drilling test were included in the study. The time from administration of the injection to the patients’ reporting pins and needles was recorded by an independent dental nurse. All tested patients reported sufficient anaesthesia during the drilling test. In the segmental acupuncture group, anaesthesia was achieved after 62 seconds, compared to the heterosegmental superficial acupuncture group, who took 115 seconds and the control group, who received standard treatment only, and took 119 seconds. The difference between the segmental acupuncture group and the heterosegmental superficial acupuncture group was statistically significant (p<0.015); the difference between the segmental acupuncture group and the control, who received a regional inferior dental block only, was also significant (p<0.032). No significant difference was found between the heterosegmental superficial acupuncture group and the control group who received a regional inferior dental block only (p<0.84). It appears from this pilot study that the onset time of local anaesthesia is reduced if segmentally administered acupuncture is given prior to the regional inferior dental block. However, it needs to be reproduced including objective measurements.

Immediate Effects of Kinesio Taping on pain in Athletes with Patellofemoral Pain Syndrome

2020 ◽  
Author(s):  
Neelam Rehman ◽  
Muhammad Kashif ◽  
AbdulGhafoor Sajjad ◽  
Hafiz Muhammad Junaid Hassan ◽  
Humaira Iram
Keyword(s):  
Treatment Group ◽  
Rating Scale ◽  
Pain Syndrome ◽  
Patellofemoral Pain Syndrome ◽  
Patellofemoral Pain ◽  
Control Group ◽  
P Value ◽  
Kinesio Taping ◽  
Significant Difference ◽  
The Difference

Abstract Background Ligaments injury and anterior knee pain is the most common problem in the knee joint. In practice, there are various interventions for the treatment of patellofemoral pain syndrome (PFPS). Kinesio taping is one of them, but little literature is available on the immediate effects of treating this problem. Methodology From June to September 2017, a randomized control study was conducted at the Army Sports Complex GHQ Rawalpindi to determine the effectiveness of Kinesio Taping (KT) in patellofemoral pain syndrome in athletes. Data were collected from 48 athletes who fully met the inclusion criteria and were randomly divided into 2 groups. The data collection tool was Numerical Pain Rating Scale (NPRS), Kujala PFPS Score, and self-structured Questionnaire. The data was analyzed on SPSS 21. Results The overall mean age was 22.7±3.0. The immediate effects showed improved NPRS in both groups; in the control group the NPRS pre 1st visit mean was 5.36±1.2 and post 1st visit mean was 4.68±1.3 with the difference of 0.68±0.1 having p value p<0.001. In the treatment group the NPRS pre 1st visit mean was 5.90±1.2 and post 1st visit mean was 5.00±1.0 with the difference of 0.90±0.1 having p value p<0.001. Conclusion This study shows immediate effects of Kinesio-Taping, however there was not any significant difference between both groups but the treatment group performed well after the sessions.

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