scholarly journals Bike Shop

2021 ◽  
Author(s):  
◽  
Liang Chen
Keyword(s):  
Design Research ◽  
Fossil Fuel ◽  
Large Population ◽  
Transport Systems ◽  
Site Conditions ◽  
New Model ◽  
Linear Sequence ◽  
Wide Range ◽  
Integrated Facility ◽  
Kit Of Parts

<p>The aim of the research is to develop a new model of bicycling supporting infrastructure that is cost-efficient, easily fabricated and installed, energy-efficient, globally transportable and adaptable to site. Cycling has entered into a new era, with a large population of active cyclists competing with unsustainable fossil fuel transport systems. The increase in cycling is a result of rising fossil fuel costs and a more environmentally aware public. The thesis seeks an architectural way of provoking greater incentives for cycling by increasing its appeal and ease of engagement, while decreasing related infrastructure costs.  The design proposes ‘Bike Shop’, an architecturally integrated cycling support facility that can be positioned at regular intervals along a cycling route. The design research challenge is to conceive a facility that is self-sustaining, adaptable, economically produced, environmentally sensitive, portable and able to be applied globally. As a vehicle for design, the Great Harbour Way/Te Aranui o Pōneke will be used. The Great Harbour Way includes plans for a parallel cycling route that stretches over 50 kilometres along the shoreline in the Greater Wellington region from Eastbourne to Owhiro Bay. The Greater Wellington Regional Council has proposed their second highest funding of large projects over $5 million for walking and cycling development in the region. The funding of $17.05 million goes towards the development for a walkway/cycleway between Ngaraunga and Petone. This thesis will test how prefabricated methods such as kit-of-parts and mass customisation techniques can reduce costs yet encourage adaptability to address the wide range of conditions that the Great Harbour Way offers. The challenge of the design experiment for this facility will be to become a new model of cycling infrastructure around the world.  The thesis proposes to reinterpret the Bike Shop as a linear sequence of cycling facilities that inhabit the Great Harbour Way. The Bike Shop is to be placed on this stretch of shoreline at fixed intervals. At these locations with the wide range of site conditions the design challenge is for the facility to arrive as a kit-of-parts, be assembled quickly and adapted to unique site conditions.  The thesis proposes a program where each architecturally integrated facility along the linear sequence will function as new cycling infrastructure, where simultaneously a bike can be repaired or a tire can be inflated or a bicyclist can rest and rehydrate with other cyclists off the road. In this way, each facility will promote safe cycling, thereby providing safety, environmentally sustainable energy, and public health benefits to more cyclists. In this way, the thesis argues that the facilities will be recognized as signifiers of the city as well as markers of location and orientation. Overall this thesis invites prefabricated elements to be adaptable in ways that make them responsive and beautifully reflect the site rather than just repetitive.</p>

scholarly journals Bike Shop

2021 ◽  
Author(s):  
◽  
Liang Chen
Keyword(s):  
Design Research ◽  
Fossil Fuel ◽  
Large Population ◽  
Transport Systems ◽  
Site Conditions ◽  
New Model ◽  
Linear Sequence ◽  
Wide Range ◽  
Integrated Facility ◽  
Kit Of Parts

<p>The aim of the research is to develop a new model of bicycling supporting infrastructure that is cost-efficient, easily fabricated and installed, energy-efficient, globally transportable and adaptable to site. Cycling has entered into a new era, with a large population of active cyclists competing with unsustainable fossil fuel transport systems. The increase in cycling is a result of rising fossil fuel costs and a more environmentally aware public. The thesis seeks an architectural way of provoking greater incentives for cycling by increasing its appeal and ease of engagement, while decreasing related infrastructure costs.  The design proposes ‘Bike Shop’, an architecturally integrated cycling support facility that can be positioned at regular intervals along a cycling route. The design research challenge is to conceive a facility that is self-sustaining, adaptable, economically produced, environmentally sensitive, portable and able to be applied globally. As a vehicle for design, the Great Harbour Way/Te Aranui o Pōneke will be used. The Great Harbour Way includes plans for a parallel cycling route that stretches over 50 kilometres along the shoreline in the Greater Wellington region from Eastbourne to Owhiro Bay. The Greater Wellington Regional Council has proposed their second highest funding of large projects over $5 million for walking and cycling development in the region. The funding of $17.05 million goes towards the development for a walkway/cycleway between Ngaraunga and Petone. This thesis will test how prefabricated methods such as kit-of-parts and mass customisation techniques can reduce costs yet encourage adaptability to address the wide range of conditions that the Great Harbour Way offers. The challenge of the design experiment for this facility will be to become a new model of cycling infrastructure around the world.  The thesis proposes to reinterpret the Bike Shop as a linear sequence of cycling facilities that inhabit the Great Harbour Way. The Bike Shop is to be placed on this stretch of shoreline at fixed intervals. At these locations with the wide range of site conditions the design challenge is for the facility to arrive as a kit-of-parts, be assembled quickly and adapted to unique site conditions.  The thesis proposes a program where each architecturally integrated facility along the linear sequence will function as new cycling infrastructure, where simultaneously a bike can be repaired or a tire can be inflated or a bicyclist can rest and rehydrate with other cyclists off the road. In this way, each facility will promote safe cycling, thereby providing safety, environmentally sustainable energy, and public health benefits to more cyclists. In this way, the thesis argues that the facilities will be recognized as signifiers of the city as well as markers of location and orientation. Overall this thesis invites prefabricated elements to be adaptable in ways that make them responsive and beautifully reflect the site rather than just repetitive.</p>

scholarly journals Planetary Nebulae in M31: Abundances, and comparison with bright Planetary Nebulae in the LMC

1997 ◽  
Vol 180 ◽  
pp. 475-476
Author(s):  
M. G. Richer ◽  
G. Stasińska ◽  
M. L. McCall
Keyword(s):  
Planetary Nebula ◽  
Luminosity Function ◽  
Large Population ◽  
Wavelength Region ◽  
Planetary Nebulae ◽  
Surprising Result ◽  
Population Synthesis ◽  
Abundance Distribution ◽  
Wide Range ◽  
The Mean

We have obtained spectra of 28 planetary nebulae in the bulge of M31 using the MOS spectrograph at the Canada-France-Hawaii Telescope. Typically, we observed the [O II] λ3727 to He I λ5876 wavelength region at a resolution of approximately 1.6 å/pixel. For 19 of the 21 planetary nebulae whose [OIII]λ5007 luminosities are within 1 mag of the peak of the planetary nebula luminosity function, our oxygen abundances are based upon a measured [OIII]λ4363 intensity, so they are based upon a measured electron temperature. The oxygen abundances cover a wide range, 7.85 dex < 12 + log(O/H) < 9.09 dex, but the mean abundance is surprisingly low, 12 + log(O/H)–8.64 ± 0.32 dex, i.e., roughly half the solar value (Anders & Grevesse 1989). The distribution of oxygen abundances is shown in Figure 1, where the ordinate indicates the number of planetary nebulae with abundances within ±0.1 dex of any point on the x-axis. The dashed line indicates the mean abundance, and the dotted lines indicate the ±1 σ points. The shape of this abundance distribution seems to indicate that the bulge of M31 does not contain a large population of bright, oxygen-rich planetary nebulae. This is a surprising result, for various population synthesis studies (e.g., Bica et al. 1990) have found a mean stellar metallicity approximately 0.2 dex above solar. This 0.5 dex discrepancy leads one to question whether the mean stellar metallicity is as high as the population synthesis results indicate or if such metal-rich stars produce bright planetary nebulae at all. This could be a clue concerning the mechanism responsible for the variation in the number of bright planetary nebulae observed per unit luminosity in different galaxies (e.g., Hui et al. 1993).

Phase equilibria modeling of biorefinery-related systems: a systematic review

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Marcos L. Corazza ◽  
Julia Trancoso
Keyword(s):  
Phase Equilibria ◽  
Phase Behavior ◽  
Fossil Fuel ◽  
Process Conditions ◽  
Design And Optimization ◽  
Waste Reuse ◽  
Wide Range ◽  
Prisma Statement ◽  
Fuel Substitution ◽  
The Subject

Abstract The search for sustainable ideas has gained prominence in recent decades at all levels of society since it has become imperative an economic, social, and environmental development in an integrated manner. In this context, biorefineries are currently present as the technology that best covers all these parameters, as they add the benefits of waste reuse, energy cogeneration, and fossil fuel substitution. Thus, the study of the various applicable biological matrices and exploring the technical capabilities of these processes become highly attractive. Thermodynamic modeling acts in this scenario as a fundamental tool for phase behavior predictions in process modeling, design, and optimization. Thus, this work aimed to systematize, using the PRISMA statement for systematic reviews, the information published between 2010 and 2020 on phase equilibria modeling in systems related to biorefineries to organize what is already known about the subject. As a result, 236 papers were categorized in terms of the year, country, type of phase equilibria, and thermodynamic model used. Also, the phase behavior predictions of different thermodynamic models under the same process conditions were qualitatively compared, establishing PC-SAFT as the model that best represents the great diversity of interest systems for biorefineries in a wide range of conditions.

scholarly journals A high-throughput and sensitive methodology for the quantification of urinary 8-hydroxy-2′-deoxyguanosine: measurement with gas chromatography-mass spectrometry after single solid-phase extraction

2004 ◽  
Vol 380 (2) ◽  
pp. 541-548 ◽  
Author(s):  
Hai-Shu LIN ◽  
Andrew M. JENNER ◽  
Choon Nam ONG ◽  
Shan Hong HUANG ◽  
Matthew WHITEMAN ◽  
...  
Keyword(s):  
Gas Chromatography ◽  
Solid Phase Extraction ◽  
Healthy Subjects ◽  
Solid Phase ◽  
Large Population ◽  
Urine Samples ◽  
Gas Chromatography Mass Spectrometry ◽  
Phase Extraction ◽  
Freeze Dried ◽  
Wide Range

8-Hydroxy-2´-deoxyguanosine (8OHdG) is a widely used biomarker for the measurement of endogenous oxidative DNA damage. A sensitive method for the quantification of 8OHdG in urine by single solid-phase extraction and GC-MS (gas chromatography with MS detection) using selective ion monitoring is described in the present study. After solid-phase extraction, samples are freeze-dried, derivatized by trimethylsilylation and analysed by GC-MS. The urinary 8OHdG was quantified using heavy isotope dilution with [18O]8OHdG. The recovery of 8OHdG after the solid-phase extraction ranged from 70 to 80% for a wide range of urinary 8OHdG levels. Using 1 ml of urine, the limit of quantification was >2.5 nM (2.5 pmol/ml) and the calibration curve was linear in the range 2.5–200 nM. This method was applied to measure 8OHdG in urine samples from 12 healthy subjects. The intra- and inter-day variations were <9%. Urinary 8OHdG levels in spot urine samples from four healthy subjects were also measured for 1 week and, again, the variation was small. The presence of H2O2 in urine did not cause artifactual formation of 8OHdG. Since this assay is simple, rapid, sensitive and reproducible, it seems suitable to be used as a routine methodology for the measurement of urinary excretion of 8OHdG in large population studies.

scholarly journals Use of simulation model for measurement of MilkRun system performance

2019 ◽  
Vol 9 (1) ◽  
pp. 600-605 ◽  
Author(s):  
Gabriel Fedorko ◽  
Martin Vasil ◽  
Michaela Bartosova
Keyword(s):  
Simulation Model ◽  
Production Systems ◽  
Operational Performance ◽  
Transport Systems ◽  
Indirect Methods ◽  
Operational Characteristics ◽  
Wide Range ◽  
Effective Operation ◽  
And Performance ◽  
Plant Simulation

AbstractIntra-plant transport systems within their operation directly impact on the performance of production systems. For their effective operation, it is, therefore, necessary to realize evaluation of operational performance and effectivity. For the realization of this type of evaluation, in addition to a wide range of sensors that can be difficult for installation and operation, we can also use indirect methods that are equally able to provide reliable operational characteristics. Indirect analytical methods are presented above all by the approach which is based on the use of simulation methods. The method of computer simulation provides a wide range of options for the evaluation of efficiency and performance. The paper describes the use of a simulation model created in the program Tecnomatix Plant Simulation for analyzing the supply of production workplaces within the MilkRun system.

scholarly journals The potential of forest-derived bioenergy to contribute to China's future energy and transportation fuel requirements

2012 ◽  
Vol 88 (05) ◽  
pp. 547-552
Author(s):  
Ling Li ◽  
Sergios Karatzos ◽  
Jack Saddler
Keyword(s):  
Cellulosic Ethanol ◽  
First Generation ◽  
Fossil Fuel ◽  
Large Population ◽  
Forest Biomass ◽  
Marginal Land ◽  
Transportation Fuel ◽  
Transportation Fuels ◽  
Energy Dependent

Increasing concerns of oil security, greenhouse gas emissions, and sustainability have encouraged nations to consider the contribution that agriculture/forestry for bioenergy (and biofuels in particular) could make as alternatives to current fossil-based energy and transportation fuels. Despite China's large population and geographical size, it has only relatively recently developed into a highly industrialized and energy-dependent economy. Coal is, and will remain, China's dominant energy source. However, over the last few years with China's growing middle class, increasing growth in production and sale of cars/trucks and a growing chemical based sector, oil and its derivatives are predicted to experience the fastest fossil fuel growth. China's ability to produce so-called “first-generation” or conventional biofuels from sugar, starch or vegetable oil based plants is very restricted because of “food vs. fuel” issues. Thus, biomass-based and forest-based biofuels, in particular, can form a medium-to-long-term solution that could contribute to China's national biofuels targets. Oilseed trees have been suggested as an initial forest-based biodiesel strategy with about 13 million ha of marginal land identified for possible plantation. It is also estimated that 17 million tonnes of cellulosic ethanol per annum could be derived from forest biomass that is currently available in China.

Pregnancy Experience after Delivery of a Child with a Major Birth Defect: A Population Study

PEDIATRICS ◽  
1995 ◽  
Vol 95 (1) ◽  
pp. 59-65
Author(s):  
Margarett K. Davis ◽  
Muin J. Khoury ◽  
J. David Erickson
Keyword(s):  
Birth Defects ◽  
Reproductive Behavior ◽  
Birth Defect ◽  
Large Population ◽  
Population Based ◽  
Subsequent Pregnancy ◽  
Pregnancy Rates ◽  
Wide Range ◽  
First Year Of Life ◽  
And Control

Objective. Data from a large population-based, case-control study were analyzed to determine whether women giving birth to children with major birth defects have different subsequent pregnancy patterns than those giving birth to live-born babies without defects. Other studies examining this phenomenon have been smaller, have not been population-based, or have not addressed the different effects that a wide range of major defects might have on mothers' subsequent pregnancy rates. Methods. Mothers of 4918 infants with major birth defects born from 1968 through 1980 in metropolitan Atlanta were compared with mothers of 3029 control infants, frequency-matched on birth year, birth hospital, and race. Results. The pregnancy rate in the first 3 years after the index birth was higher among case mothers (36%) than among control mothers (30%, P &lt; .0001). This excess was seen for mothers of stillborn case infants (64%) and mothers of case infants who died in infancy (58%), but not for mothers of case infants who survived the first year of life (31%). Pregnancy rates varied by birth defect type. Maternal and infant factors varied among case and control subjects and influenced subsequent pregnancy rates. Conclusion. The reproductive behavior observed in this study supports the theory that mothers of nonsurviving children with birth defects compensate by acting to "replace" the lost child. Reproductive behavior was also strongly associated with having completed a previous pregnancy and by the type of birth defect.

scholarly journals Root crops agroforestry for greening the sustainability of green revolution

2018 ◽  
Vol 8 (1) ◽  
pp. 26-37
Author(s):  
Y Widodo ◽  
S Wahyuningsih ◽  
JS Utomo ◽  
A Subagio
Keyword(s):  
Climate Change ◽  
Forest Canopy ◽  
Fossil Fuel ◽  
Agricultural Land ◽  
Green Revolution ◽  
Forest Conversion ◽  
World Population ◽  
Root Crops ◽  
Wide Range ◽  
Agro Forestry

Green revolution started at mid of twentieth century was the answer of anxiousness reminded by Malthusian that food scarcity problems in relation with population growth. In concurrence with exploitation of fossil fuel for agriculture mechanization as well as agrochemicals in the form of inorganic fertilizer and pesticide, green revolution by introducing high yielding varieties of cereals and grains was able to nourish the world population by increasing productivity. Indeed, from beginning of mechanization with fossil fuel based as advised by Rudolf Diesel then Arrhenius would be affected to the release of CO2 to the atmosphere and consequently exaggerating climate change as suffered by current and future generations. Under green revolution based on cereals and grains affected forest conversion into open agricultural land, because both commodities are sun-loving crops, which are hate to the shade. On the other hand, to slow the severity of climate change natural forest must be conserved tightly. Entering third millennium demand of food production with ecologically friendly is stronger. Hence, green revolution needs to be amended into greener perspectives. Thus, implementation of agro-forestry into wide range of agro-ecological zone is urgently innovated. Fortunately, shade tolerant of root crops has significant advantage to be developed under agro-forestry. Under shade of forest canopy at basal forest strata, root crops are able to sequester CO2 to be converted into carbohydrate and other compounds to provide food for the dweller. Back to nature is not only a slogan, with root crops under agro-forestry is a reality; fresh root up to 30 t ha-1 can be harvested yearly as the source of food and renewable fuel as well. This potential is very worthy to improve and greening the existing green revolution to be more sustainable.Int. J. Agril. Res. Innov. & Tech. 8 (1): 26-37, June, 2018

scholarly journals Baseline characteristics of idiopathic pulmonary fibrosis: analysis from the Australian Idiopathic Pulmonary Fibrosis Registry

2017 ◽  
Vol 49 (2) ◽  
pp. 1601592 ◽  
Author(s):  
Helen E. Jo ◽  
Ian Glaspole ◽  
Christopher Grainge ◽  
Nicole Goh ◽  
Peter M.A. Hopkins ◽  
...  
Keyword(s):  
Idiopathic Pulmonary Fibrosis ◽  
Pulmonary Fibrosis ◽  
Disease Severity ◽  
Large Population ◽  
Underlying Disease ◽  
National Registry ◽  
Hazard Ratio ◽  
Wide Range ◽  
Baseline Characteristics

The prevalence of idiopathic pulmonary fibrosis (IPF), a fatal and progressive lung disease, is estimated at 1.25–63 out of 100 000, making large population studies difficult. Recently, the need for large longitudinal registries to study IPF has been recognised.The Australian IPF Registry (AIPFR) is a national registry collating comprehensive longitudinal data of IPF patients across Australia. We explored the characteristics of this IPF cohort and the effect of demographic and physiological parameters and specific management on mortality.Participants in the AIPFR (n=647, mean age 70.9±8.5 years, 67.7% male, median follow up 2 years, range 6 months–4.5 years) displayed a wide range of age, disease severity and co-morbidities that is not present in clinical trial cohorts. The cumulative mortality rate in year one, two, three and four was 5%, 24%, 37% and 44% respectively. Baseline lung function (forced vital capacity, diffusing capacity of the lung for carbon monoxide, composite physiological index) and GAP (gender, age, physiology) stage (hazard ratio 4.64, 95% CI 3.33–6.47, p<0.001) were strong predictors of mortality. Patients receiving anti-fibrotic medications had better survival (hazard ratio 0.56, 95% CI 0.34–0.92, p=0.022) than those not on anti-fibrotic medications, independent of underlying disease severity.The AIPFR provides important insights into the understanding of the natural history and clinical management of IPF.

scholarly journals 2000 Fleming Lecture. The origin and evolution of hepatitis viruses in humans

2001 ◽  
Vol 82 (4) ◽  
pp. 693-712 ◽  
Author(s):  
Peter Simmonds
Keyword(s):  
Large Population ◽  
Human Populations ◽  
Hepatitis Viruses ◽  
Hepatitis G Virus ◽  
Origin And Evolution ◽  
Wide Range ◽  
Population Sizes ◽  
History Of ◽  
Virus C ◽  
Time Of Divergence

The spread and origins of hepatitis C virus (HCV) in human populations have been the subject of extensive investigations, not least because of the importance this information would provide in predicting clinical outcomes and controlling spread of HCV in the future. However, in the absence of historical and archaeological records of infection, the evolution of HCV and other human hepatitis viruses can only be inferred indirectly from their epidemiology and by genetic analysis of contemporary virus populations. Some information on the history of the latter may be obtained by dating the time of divergence of various genotypes of HCV, hepatitis B virus (HBV) and the non-pathogenic hepatitis G virus (HGV)/GB virus-C (GBV-C). However, the relatively recent times predicted for the origin of these viruses fit poorly with their epidemiological distributions and the recent evidence for species-associated variants of HBV and HGV/GBV-C in a wide range of non-human primates. The apparent conservatism of viruses over long periods implied by these latter observations may be the result of constraints on sequence change peculiar to viruses with single-stranded genomes, or with overlapping reading frames. Large population sizes and intense selection pressures that optimize fitness may be the factors that set virus evolution apart from that of their hosts.

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