Indexes of Dynamics of Sickness and Occurrence of the Urinary System Infectious-Inflammatory Diseases in Children of Chernivtsi Region

The article presents the results of the research of etiological structure of urinary tract infection among children. Out of the total number of urological and nephrological sick children`s research, it is defined that 283 microorganisms selected from the urine were found. 63.2 % of the total number of children in nephrological department is related to only urological diseases. In recent, there has been an open trend to increase a frequency of diseases of the urinary system. Over the past five years, the number of diseases of the genitourinary system in urban children in Kazakhstan has increased to 65 %.The review shows that inflammatory diseases of kidneys and urinary tract take the second place after acute respiratory diseases of upper breathing tract. In this work, it is established that a causative agent of urinary system infection among children is pathogenic, as well as relative-pathogenic microorganisms. As it is shown, the leading etiological agent of uroinfection is Staphylococcus epidermidis (13.9 %), Escherichia coli (12.2 %), Enterobacter cloacae (7.8 %). In some cases, streptococcus are excreted. Also, there were dominant pathogens of nephroinfection among children such as Escherichia coli (21.1 %), Enterococcus faecalis (9.6 %), Staphylococcus epidermidis (20.1 %). Some types of Candida fungi in the formation of the urinary tract and kidney infection (mostly C.albicans (9.5 %), C.kruseae (8.1 %), C.glabrata (5.6 %) pathogens) are observed in the study of urine in children. During the general research, it was found that the etiological agents of urinary system among children consist of a huge microbiological spectrum, especially among children living in urban areas.

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Microbial inflammatory diseases of the urinary system in children

Modern pediatrics. Ukraine ◽

10.15574/sp.2019.104.57 ◽

2019 ◽

pp. 57-70

Author(s):

T.V. Budnik ◽

Keyword(s):

Inflammatory Diseases ◽

Urinary System

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Activity of kallikrein-kinin system in children in norm and at some pathological states

Bulletin of Siberian Medicine ◽

10.20538/1682-0363-2009-4(2)-61-69 ◽

2009 ◽

Vol 8 (4(2)) ◽

pp. 61-69

Author(s):

Ye. I. Kondratiyeva ◽

T. Ye. Tropova ◽

G. A. Sukhanova ◽

A. A. Terentiyeva ◽

T. S. Krivonogova ◽

...

Keyword(s):

Metabolic Syndrome ◽

Protease Inhibitor ◽

Blood Plasma ◽

Inflammatory Diseases ◽

Healthy Children ◽

Urinary System ◽

Kinin System ◽

Α2 Macroglobulin ◽

Kallikrein Kinin System ◽

Ischemic Encephalopathy

Proteolytic systems of tissue and blood plasma take part in the processes of adaptation and protection of an organism, as well as in development of pathological reactions. We have studied the activity of kallikrein, kallikreinogen, angiotensine transforming enzyme, α1-protease inhibitor, and α2-macroglobulin in healthy children in different age periods, in newborns with hypoxic-ischemic encephalopathy, in children with infectious-inflammatory diseases of the urinary system, obesity, and metabolic syndrome.The activity of the kallikrein-kinin system was increased in all the groups against the background of the decreased inhibitory activity of blood plasma of different intensity, which can be used for the prediction of the course of diseases.

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Indications and Contraindications for Cystography, Diagnostic Value of the Method

Spravočnik vrača obŝej praktiki (Journal of Family Medicine) ◽

10.33920/med-10-2010-08 ◽

2020 ◽

pp. 54-59

Author(s):

Roman Petrovich Stepchenkov

Keyword(s):

Clinical Picture ◽

Inflammatory Diseases ◽

Diagnostic Value ◽

Diagnostic Methods ◽

General Analysis ◽

Malignant Neoplasms ◽

Urinary System ◽

Bladder Abnormalities ◽

Rupture Of The Bladder

Diseases of the urinary system are quite common, both among adults and among children. If, in case of infectious and inflammatory diseases of the urinary organs, an assessment of the clinical picture and general analysis of the urine is sufficient to make a diagnosis, in a number of other situations — trauma and rupture of the bladder, abnormalities of its development, malignant neoplasms — visualization of the organ is needed. One of these diagnostic methods is cystography.

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Imaging findings of infectious and inflammatory diseases of the urinary system mimicking neoplastic diseases

Abdominal Radiology ◽

10.1007/s00261-019-02222-w ◽

2019 ◽

Vol 45 (4) ◽

pp. 1110-1121

Author(s):

Ali Devrim Karaosmanoglu ◽

Aycan Uysal ◽

Musturay Karcaaltincaba ◽

Deniz Akata ◽

Mustafa Nasuh Ozmen ◽

...

Keyword(s):

Inflammatory Diseases ◽

Urinary System ◽

Imaging Findings ◽

Neoplastic Diseases

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Approaches to Treatment of Infections of Lower Urinary Tracts in Women of Reproductive Age

HEALTH OF WOMAN ◽

10.15574/hw.2017.122.81 ◽

2017 ◽

pp. 81-92

Author(s):

O.V. Romashchenko ◽

◽

V.M. Grygorenko ◽

V.V. Biloholovska ◽

L.O. Lebid ◽

...

Keyword(s):

Inflammatory Process ◽

Inflammatory Diseases ◽

Clinical Analysis ◽

Reproductive Age ◽

Gardnerella Vaginalis ◽

Urinary System ◽

Reproductive Systems ◽

Women Of Reproductive Age ◽

Anti Inflammatory ◽

Lower Urinary

Infections of urinary tracts (IUT) occupy a priority place both in the level of their outspread and the emergence of recurrences of the disease in ambulatory and stationary practice of a doctor; they are conditioned by inflammatory process, mostly of bacterial genesis, developed in different anatomic parts of urinary system – from fascia renalis to external urethral opening and often combined with pelvic inflammatory diseases. Purpose of research: to evaluate the effectiveness of complex therapy of chronic recidivating cystitis in combination with pelvic inflammatory diseases in women of reproductive age. Materials and Methods. A complex clinical and microbiological examination of 39 women aged from 18 to 39 having chronic reccurent cystitis in combination with pelvic inflammatory diseases in the observation dynamics (before and after the course of anti-inflammatory therapy with the inclusion of Tiflox and probiotic Lactovit Forte) was carried out. Results. As a result of the carried out research the symptomatic development of chronic reccurent cystitis at the background of latent development of pelvic inflammatory diseases was established. In the etiological spectre of chronic reccurent cystitis there were more often microorganisms (mostly E.coli – 82.1%) in the monoculture of critical and high number of microbs, and in 17 (43.5%) mixt-infection was established. Concordance when establishing Chlamydia (7.7%), Mycoplasmas (5.1%), Ureaplasmas (10.3%), Candida (33.4%), and Gardnerella vaginalis (10.3%) both in the biomaterial from urethra and genitals in comparison with the spectre of clinical characteristics certified the presence of interconnection of urinary and reproductive systems, which has to be considered when conducting complex anti-inflammatory therapy. Conclusion. Treatment of chronic reccurent cystitis should be conducted considering the heaviness and level of changes in the inflammatory process both from the side of urinary and reproductive systems in a single context. Only after the clinical analysis of all factors in combination it is possible to determine the tactics of treatment of infections of urinary system in women of reproductive age with the prescription of grounded and adequate therapy. Key words: infections of lower urinary tracts, pelvic inflammatory diseases, women of reproductive age, diagnostics, treatment of acute and chronic recurrent cystitis, Tiflox, Lactovit Forte.

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Medical management: a model for giving medical aid to children with infectious-inflammatory diseases of the urinary system

Journal of Medicine and Life ◽

10.25122/jml-2021-0104 ◽

2021 ◽

Vol 14 (4) ◽

pp. 504-510

Author(s):

Volodymyr Volodymyrovych Bezruk ◽

◽

Igor Dmytrovych Shkrobanets ◽

Oleksii Serhiiovych Godovanets ◽

Oleksandr Hryhorovych Buriak ◽

...

Keyword(s):

Statistical Data ◽

Inflammatory Diseases ◽

Rational Approach ◽

Urinary System ◽

Bacteriological Study ◽

Medical Aid ◽

Regional Center ◽

Medical Observation ◽

Nephrology Care ◽

Improved Model

Increasing requirements of medical aid given to children with infectious-inflammatory diseases of the urinary system stipulate the necessity to improve its quality using evidence-based therapeutic-diagnostic and organization technologies. The aim of the work – to substantiate, develop the improved model of the specialized nephrology care for children with infectious inflammatory diseases of the urinary system at the regional level. The official statistical data have been studied (2006 to 2017); information-analytical and statistical methods have been used. A bacteriological study (2009–2016) of urine samples was carried out for 3089 children (0–17 years old) in the Chernivtsi region. They formed the foundation for substantiation and development of an improved functional-organizational model of the system. In addition to the existing and functionally changed elements contains new elements: regional/inter-regional center of specialized medical aid to children with infectious-inflammatory diseases of the urinary system. Implementation of the elements of the suggested improved model in a part of a rational approach in distribution of functions concerning medical observation of patients at the stages of giving medical aid enabled to make the period of hospitalization of nephrological patients 11,40% shorter and an average period of treatment of patients with infectious-inflammatory diseases of the urinary system 2,93% shorter.

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Infectious and Inflammatory Diseases of the Urinary System

Spravočnik vrača obŝej praktiki (Journal of Family Medicine) ◽

10.33920/med-10-2010-04 ◽

2020 ◽

pp. 27-34

Author(s):

Georgiy Rubenovich Petrosyan

Keyword(s):

Urinary Tract ◽

Urinary Tract Infections ◽

Spinal Cord Injuries ◽

Inflammatory Diseases ◽

The Elderly ◽

Winter Period ◽

Urinary System ◽

Increased Risk ◽

Causative Agents ◽

Tract Infections

Urinary tract infections are the most common bacterial lesions of humans. About 150 million cases of these diseases are registered annually in the world. About 95 % of urinary tract infections occur when bacteria migrate ascending from the urethra to the bladder, and in acute uncomplicated pyelonephritis, from the ureter to the kidney. An increased risk of developing urinary tract infections is observed in infants, the elderly, pregnant women, patients with spinal cord injuries, diabetes mellitus, multiple sclerosis, immunodeficiency diseases, structural abnormalities of the kidneys and urinary tract. The autumn-winter period is a traditional season of development and exacerbation of diseases of the urinary system. This is facilitated by a high risk of hypothermia, a relative decrease in physical activity, a change in the drinking regime and a partial decrease in the body's defenses against colds. The main and most common inflammatory diseases of the urinary system include urethritis, cystitis, pyelonephritis. Due to the anatomical features of the structure of the urethra (the urethra of men is longer and narrower than that of women), urethritis of various etiologies are more common in the stronger sex. Women, for the most part, suffer from cystitis, since the causative agents of infection easily bypass the short and relatively wide urethra and immediately enter the bladder, where they find fairly favorable conditions for reproduction [5].

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Medical and Social Component of Medical Management: Improving the Model of Providing Medical Aid for Children with Infectious-Inflammatory Diseases of the Urinary System

Ukraïnsʹkij žurnal medicini bìologìï ta sportu ◽

10.26693/jmbs06.05.270 ◽

2021 ◽

Vol 6 (5) ◽

pp. 270-275

Author(s):

V. V. Bezruk ◽

◽

M. I. Velia ◽

O. V. Makarova ◽

O. Y. Yurkiv ◽

...

Keyword(s):

Urinary Tract Infection ◽

Urinary Tract ◽

Tract Infection ◽

Medical Care ◽

Inflammatory Diseases ◽

Regional Level ◽

Rational Approach ◽

Urinary System ◽

Medical Aid ◽

Improved Model

The purpose of the study was to substantiate and develop the improved model of the specialized nephrology care for the children with infectious inflammatory diseases of the urinary system at the regional level. Materials and methods. The official statistical data have been studied (reports on the state of medical care for children in the Chernivtsi region and data from the Center of medical statistics of the Ministry of Healthcare from 2006 to 2017), information-analytical and statistical methods have been used. The modern etiological structure of uropathogens – urinary tract infection pathogens among the children of the Chernivtsi region (2009-2016) was studied. Clinical and laboratory examination of 3,089 children (0-17 years old) was conducted in the region; the regional spectrum of sensitivity to antibacterial drugs was determined among the main groups of urinary tract infection pathogens; their age, gender and administrative-territorial differences among the children's population of the region are analyzed. Results and discussion. During 2012-2017 there was a significant increase (by 23.0%) in the incidence of infectious and inflammatory groups of the urinary system diseases among children of 0-14 years old, while among adolescents there was simultaneously an intensive decrease in indicators (by 40.0%) compared to 8.7% in 2006-2011. The ratio of indicators and their dynamics suggests that the growth of sick adolescents is largely due to the insufficient effectiveness of medical care, while children of 0-14 years old is due to their low and insufficient prevention. The data formed the foundation for substantiation and development of an improved functional-organizational model of the system. In addition to the existing and functionally changed elements the model contains new elements: regional/inter-regional center of specialized medical aid for children with infectious-inflammatory diseases of the urinary system. Conclusion. Implementation of the elements of the suggested improved model in a part of a rational approach in distribution of functions concerning medical observation of patients at the stages of providing medical aid enabled to make the period of hospitalization of nephrological patients by 11.40% shorter and an average period of treatment of patients with infectious-inflammatory diseases of the urinary system by 2.93% shorter. Efficiency of implementation of certain elements of the suggested model with its positive evaluation by independent experts and its compliance with the strategy of branch reforms enables to recommend the improved functional-organization model of providing medical aid for children with infectious-inflammatory diseases of the urinary system at the regional level to be introduced into the health care system of Ukraine

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