scholarly journals Knowledge, attitudes and practices concerning Middle East respiratory syndrome among Umrah and Hajj pilgrims in Samsun, Turkey, 2015

2015 ◽  
Vol 20 (38) ◽  
Author(s):  
Mustafa Kursat Sahin ◽  
Servet Aker ◽  
Ebru Kaynar Tuncel
Keyword(s):  
Middle East ◽  
Respiratory Disease ◽  
Middle East Respiratory Syndrome ◽  
Questionnaire Study ◽  
Protective Measures ◽  
Attitudes And Practices ◽  
Knowledge Attitudes And Practices

We performed a questionnaire study to determine knowledge, attitudes and practices concerning Middle East respiratory syndrome (MERS) among people intending to participate in the Hajj or Umrah Muslim pilgrimages. Of the 381 respondents aged between 17 and 85 years, 55% had never heard of MERS, while only one in three knew that it is a respiratory disease. Approximately half were insufficiently informed about protective measures. Prospective pilgrims do not seem prepared to take such precautions.

scholarly journals Coronavirus: Penyakit Lama, Virus Lama, Kemasan Baru

2020 ◽  
Vol 2 (1) ◽  
pp. 43
Author(s):  
Heru Wijono
Keyword(s):  
Middle East ◽  
Incubation Period ◽  
Respiratory Disease ◽  
Virus Strain ◽  
Severe Pneumonia ◽  
Middle East Respiratory Syndrome ◽  
Advanced Age ◽  
Acute Respiratory Disease

Abstract— Covid -19, a virus strain and a member of family with known member as Severe Acute Respiratory Disease (SARS) or Middle East Respiratory Syndrome (MERS), but having a potentially lethal differences in not readily recognized by our immunity. Classified as betacoronavirus, with incubation period up to 14 days, the sign and symptoms can be highly variable, from asymptomatic to mild to criticalin the form of severe pneumonia. Almost half the persons infected did not show any symptoms, but in cases of people with comorbidities such as advanced age, pregnancy, obesity or other certain diseases, could increase the likelihood of morbidity and even potentially fatal. Covid-19 has spread globally, including Indonesia, with a potentially increased number of cases, prevention in covid-19 protocol is a necessity. Keywords: Covid-19, SARS, symptoms, variable, prevention Abstrak— Covid-19, yang sebelumnya dikenal sebagai virus strain dari kelompok family yang sama dengan Severe Acute Respiratory Disease (SARS) atau Middle East Respiratory Syndrome (MERS), tapi memiliki fatalitas yang secara potensial lebih tinggi, karena bersiafat novel bagi sistem imunitas kita. Termasuk betacoronavirus, dengan masa inkubasi sampai dengan 14 hari, tanda dan gejala penyakit bisa sangat bervariasi, mulai dari asimtomatik, ringan sampai berat, dalam bentuk pneumonia berat. Hamper separuh penderita yang terinfeksi tidak menunjukkan gejala sama sekali, tapi pada penderita dengan komorbiditas seperti usia lanjut, kehamilan, obesitas atau penyakit kronis tertentu, resiko moribiditas dan mortalitas dapat meningkat. Covid-19 saat ini sudah menyebar ke seluruh dunia, termasuk Indonesia, dengan adanya potensi kenaikan kasus lebih banyak, pencegahan dalam bentuk protocol covid-19 bersifat mutlak diperlukan. Kata kunci: Covid-19, SARS, gejala, bervariasi, pencegahan

scholarly journals Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Seropositive Camel Handlers in Kenya

Viruses ◽  
2020 ◽  
Vol 12 (4) ◽  
pp. 396 ◽  
Author(s):  
Alice N. Kiyong’a ◽  
Elizabeth A. J. Cook ◽  
Nisreen M. A. Okba ◽  
Velma Kivali ◽  
Chantal Reusken ◽  
...  
Keyword(s):  
Risk Factors ◽  
At Risk ◽  
High Risk ◽  
Middle East ◽  
Respiratory Disease ◽  
Risk Groups ◽  
Middle East Respiratory Syndrome ◽  
Limited Evidence ◽  
Dromedary Camels ◽  
Associated Risk Factors

Middle East respiratory syndrome (MERS) is a respiratory disease caused by a zoonotic coronavirus (MERS-CoV). Camel handlers, including slaughterhouse workers and herders, are at risk of acquiring MERS-CoV infections. However, there is limited evidence of infections among camel handlers in Africa. The purpose of this study was to determine the presence of antibodies to MERS-CoV in high-risk groups in Kenya. Sera collected from 93 camel handlers, 58 slaughterhouse workers and 35 camel herders, were screened for MERS-CoV antibodies using ELISA and PRNT. We found four seropositive slaughterhouse workers by PRNT. Risk factors amongst the slaughterhouse workers included being the slaughterman (the person who cuts the throat of the camel) and drinking camel blood. Further research is required to understand the epidemiology of MERS-CoV in Africa in relation to occupational risk, with a need for additional studies on the transmission of MERS-CoV from dromedary camels to humans, seroprevalence and associated risk factors.

Developing an Understanding of Adolescents’ Knowledge, Attitudes, and Practices Toward COVID-19

2020 ◽  
Vol 36 (6) ◽  
pp. 430-441 ◽  
Author(s):  
Latefa Ali Dardas ◽  
Inaam Khalaf ◽  
Manar Nabolsi ◽  
Omayyah Nassar ◽  
Suhaila Halasa
Keyword(s):  
School Nurses ◽  
Control Measures ◽  
Health Practices ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Protective Measures ◽  
Attitudes And Practices ◽  
Infection Control Measures ◽  
Positive Attitudes ◽  
Knowledge Attitudes And Practices

Adolescents are more likely to engage in risky health practices related to COVID-19. Their compliance with infection control measures is a key factor to mitigate the spread of the disease. The purpose of this study was to explore the knowledge, attitudes, and practices toward COVID-19 and their correlates among Jordanian adolescents. An online cross-sectional survey was utilized. A total of 1,054 Jordanian adolescents aged 12–18 completed and returned the survey. Overall, Jordanian adolescents showed a good base of knowledge regarding COVID-19 (regardless of their demographic characteristics) and tended to hold positive attitudes toward the country’s curfew and other protective measures. The majority of adolescents reported that television and social media were their main source of information on COVID-19, while few reported receiving such information from their schools. The majority reported practicing effective health protective behaviors to prevent the spread of COVID-19, which was significantly predicted by their knowledge and attitudes toward these measures. However, there was a relatively small, yet clinically significant, percentage of adolescents who showed poor knowledge on COVID-19, had negative attitudes toward protective measures, and reported being engaged in risky practices related to infection spread. Tailored efforts are needed to improve the levels of knowledge, attitudes, and practices among adolescents. Raising awareness and promoting positive attitudes are vital to change adolescents’ health practices. Policy makers should ensure that school nurses are available in all schools and working to their full scope. School nurses are the eyes and ears of public health and primary care. They are essential members on pandemic preparedness, reopening and reentry planning teams, and can lead health care in schools and practice in a holistic culturally competent proactive manner to address the needs of students.

scholarly journals High Secretion of Interferons by Human Plasmacytoid Dendritic Cells upon Recognition of Middle East Respiratory Syndrome Coronavirus

2015 ◽  
Vol 89 (7) ◽  
pp. 3859-3869 ◽  
Author(s):  
Vivian A. Scheuplein ◽  
Janna Seifried ◽  
Anna H. Malczyk ◽  
Lilija Miller ◽  
Lena Höcker ◽  
...  
Keyword(s):  
Dendritic Cells ◽  
Middle East ◽  
Respiratory Disease ◽  
Immune Cell ◽  
Critical Role ◽  
Plasmacytoid Dendritic Cells ◽  
Middle East Respiratory Syndrome ◽  
Early Gene ◽  
Type I ◽  
Endosomal Uptake

ABSTRACTThe Middle East respiratory syndrome coronavirus (MERS-CoV) emerged in 2012 as the causative agent of a severe respiratory disease with a fatality rate of approximately 30%. The high virulence and mortality rate prompted us to analyze aspects of MERS-CoV pathogenesis, especially its interaction with innate immune cells such as antigen-presenting cells (APCs). Particularly, we analyzed secretion of type I and type III interferons (IFNs) by APCs, i.e., B cells, macrophages, monocyte-derived/myeloid dendritic cells (MDDCs/mDCs), and by plasmacytoid dendritic cells (pDCs) of human and murine origin after inoculation with MERS-CoV. Production of large amounts of type I and III IFNs was induced exclusively in human pDCs, which were significantly higher than IFN induction by severe acute respiratory syndrome (SARS)-CoV. Of note, IFNs were secreted in the absence of productive replication. However, receptor binding, endosomal uptake, and probably signaling via Toll-like receptor 7 (TLR7) were critical for sensing of MERS-CoV by pDCs. Furthermore, active transcription of MERS-CoV N RNA and subsequent N protein expression were evident in infected pDCs, indicating abortive infection. Taken together, our results point toward dipeptidyl peptidase 4 (DPP4)-dependent endosomal uptake and subsequent infection of human pDCs by MERS-CoV. However, the replication cycle is stopped after early gene expression. In parallel, human pDCs are potent IFN-producing cells upon MERS-CoV infection. Knowledge of such IFN responses supports our understanding of MERS-CoV pathogenesis and is critical for the choice of treatment options.IMPORTANCEMERS-CoV causes a severe respiratory disease with high fatality rates in human patients. Recently, confirmed human cases have increased dramatically in both number and geographic distribution. Understanding the pathogenesis of this highly pathogenic CoV is crucial for developing successful treatment strategies. This study elucidates the interaction of MERS-CoV with APCs and pDCs, particularly the induction of type I and III IFN secretion. Human pDCs are the immune cell population sensing MERS-CoV but secrete significantly larger amounts of IFNs, especially IFN-α, than in response to SARS-CoV. A model for molecular virus-host interactions is presented outlining IFN induction in pDCs. The massive IFN secretion upon contact suggests a critical role of this mechanism for the high degree of immune activation observed during MERS-CoV infection.

scholarly journals Protein Intrinsic Disorder and Evolvability of MERS-CoV

Biomolecules ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 608
Author(s):  
Vladimir N. Uversky ◽  
Elrashdy M. Redwan ◽  
Abdullah A. Aljadawi
Keyword(s):  
Middle East ◽  
Respiratory Disease ◽  
Intrinsic Disorder ◽  
Middle East Respiratory Syndrome ◽  
Protein Intrinsic Disorder ◽  
Human Coronaviruses ◽  
Viral Respiratory

Middle East Respiratory Syndrome (MERS) is a viral respiratory disease caused by one of the human coronaviruses, MERS-CoV [...]

scholarly journals A New-fangled Corona virus coupled with Human Respiratory and AI in COVID-19 Discovery

2021 ◽  
Vol 12 (1S) ◽  
pp. 13-22
Author(s):  
V. A. Kotkar, Et. al.
Keyword(s):  
Middle East ◽  
Respiratory Disease ◽  
Hubei Province ◽  
Middle East Respiratory Syndrome ◽  
Corona Virus ◽  
Positive Sense ◽  
Corona Viruses

Recently a very strange time to fight with invisible enemy. The Corona virus ailment 2019 also known as COVID-19 outburst, which emerged from Wuhan, the Hubei Province, China, had broaden to all the regions of China and 28 additional countries. Corona viruses are a group of viruses with non segmented, single stranded and positive–sense RNA genomes. Corona viruses is also popular to contaminate human hosts and effect respiratory disease like brutal SARS-CoV (Acute Respiratory Syndrome Corona virus) and MERS-CoV (Middle East Respiratory Syndrome Corona virus). In this paper we discussed on detail analysis of COVID-19 disease.

Sign in / Sign up

Export Citation Format

Share Document