scholarly journals Implications for Europe of high prevalence of HIV drug resistance in the United States

2002 ◽  
Vol 6 (2) ◽  
Author(s):  
D Pillay
Keyword(s):  
United States ◽  
Drug Resistance ◽  
Disease Progression ◽  
Successful Treatment ◽  
Virological Failure ◽  
The United States ◽  
Viral Rna ◽  
Viral Rebound ◽  
Drug Compliance ◽  
High Prevalence

Over 16 drugs are now available for use against HIV, broadly comprising three classes of agent. Their use, in combination, has had a dramatic impact in reducing disease progression. Successful treatment is increasingly defined as the maintenance of plasma viral RNA load at undetectable levels. Reasons for ‘virological failure’ (viral rebound) on treatment are many, but perhaps the single most important factor is suboptimal drug compliance.

scholarly journals A Comparison of Mental Health Outcomes in the United States and Italy at Different Levels of Cumulative COVID-19 Prevalence

2021 ◽  
Author(s):  
Anthony D Mancini ◽  
Gabriele Prati
Keyword(s):  
Mental Health ◽  
United States ◽  
New York ◽  
San Francisco ◽  
The United States ◽  
Ptsd Symptoms ◽  
General Distress ◽  
High Prevalence ◽  
Low Prevalence ◽  
Different Levels

How does the prevalence of COVID-19 impact people’s mental health? In a preregistered study (N = 857), we sought to answer this question by comparing demographically matched samples in four regions in the United States and Italy with different levels of cumulative COVID-19 prevalence. No main effect of prevalence emerged. Rather, prevalence region had opposite effects, depending on the country. New York City participants (high prevalence) reported more general distress, PTSD symptoms, and COVID-19 worry than San Francisco (low prevalence). Conversely, Campania participants (low prevalence) reported more general distress, PTSD symptoms, and COVID-19 worry than Lombardy (high prevalence). Consistent with these patterns, COVID-19 worry was more strongly linked with general distress and PTSD symptoms in New York than San Francisco, whereas COVID-19 worry was more strongly linked with PTSD in Campania than Lombardy. In exploratory analyses, media exposure predicted and mapped on to geographic variation in mental health outcomes.

scholarly journals Aetiological Factors of Osteoarthritis: A Review Update

2015 ◽  
Vol 2 (1) ◽  
pp. 18-23
Author(s):  
M. Jahidul Islam ◽  
M. Shahadat Hossain ◽  
M. Ruhul Amin ◽  
Monzur Ahmed
Keyword(s):  
United States ◽  
Joint Damage ◽  
The Elderly ◽  
The United States ◽  
Common Type ◽  
High Rate ◽  
Lumbosacral Spine ◽  
First Metatarsal ◽  
High Prevalence ◽  
Wear And Tear

Osteoarthritis (OA) is no longer considered ‘degenerative’ or ‘wear and tear’ arthritis; rather involves dynamic biomechanical, biochemical and cellular process. Indeed, the joint damage that occurs in OA is the result of active remodeling involving all the joint structures. Although articular cartilage is at the center of change, OA is viewed as a disease of the entire joint. Traditionally, OA has been viewed as an inevitable degenerative condition of the cartilage. It is currently viewed as a biomechanical and biochemical inflammatory disease of the entire joints. Osteoarthritis (OA) is the most common type of arthritis. Its high prevalence, especially in the elderly, and the high rate of disability related to disease make it a leading cause of disability in the elderly. Because of the aging of Western populations and because obesity, a major risk factor, are increasing in prevalence, the occurrence of osteoarthritis is on the rise. In the United States, osteoarthritis prevalence will increase from 66–100% by the year 2020. OA affects certain joints, yet spares others. Commonly affected joints include the cervical and lumbosacral spine, hip, knee, and first metatarsal phalangeal joint (MTP). In the hands, the distal and proximal inter-phalangeal joints and the base of the thumb are often affected. Usually spared are the wrist, elbow, and ankle.Journal of Current and Advance Medical Research 2015;2(1):18-23DOI: http://dx.doi.org/10.3329/jcamr.v2i1.22584

Handguns: Risks versus Benefits

PEDIATRICS ◽  
1986 ◽  
Vol 77 (5) ◽  
pp. 781-782
Author(s):  
KATHERINE K. CHRISTOFFEL ◽  
TOM CHRISTOFFEL
Keyword(s):  
United States ◽  
New York ◽  
New York Times ◽  
The United States ◽  
Gun Control ◽  
Second Amendment ◽  
High Prevalence ◽  
The Us ◽  
Us Supreme Court ◽  
P 16

THE ISSUE There are an estimated 40 to 50 million handguns in the United States, with approximately 2 million more being manufactured annually1 (The New York Times, July 9, 1985, p 16). The high prevalence of handgun injury in the United States is unique in all the world and is increasing. Children are among the growing legions of US citizens harmed by the handgun epidemic.2 The effort to control handguns is focussed on developing laws to control their manufacture, importation, purchase, possession, and use. Opponents of these legal approaches claim that gun control endangers constitutional freedoms. When asked, the US Supreme court has consistently rejected that position in favor of the view that the Second Amendment protects a collective, not a personal, right to bear arms.3,4

Salmonella enterica Serovar Diversity, Distribution, and Prevalence in Public Access Waters from a Central California Coastal Leafy Green Growing Region during 2011 - 2016

2021 ◽  
Author(s):  
Lisa Gorski ◽  
Anita S. Liang ◽  
Samarpita Walker ◽  
Diana Carychao ◽  
Ashley Aviles Noriega ◽  
...  
Keyword(s):  
United States ◽  
Salmonella Enterica ◽  
The United States ◽  
Public Access ◽  
Bias Analysis ◽  
Central California ◽  
High Prevalence ◽  
Human Salmonellosis ◽  
Rain Events ◽  
Growing Region

Prevalence and serovar diversity of Salmonella enterica was measured during a five-year survey of surface waters in a 500 mi^2 agricultural region of the Central California Coast. Rivers, streams, lakes, and ponds were sampled bimonthly resulting in 2,979 samples. Overall prevalence was 56.4% with higher levels detected in Spring than in Fall. Small, but significant, differences in prevalence were detected based on sample locations. Detection of Salmonella was correlated positively with both significant rain events and, in some environments, levels of generic Escherichia coli . Analysis of 1,936 isolates revealed significant serovar diversity, with 91 different serovars detected. The most common isolated serovars were S. enterica subsp. enterica serovars I 6,8:d:- (406 isolates, 21.0%, and potentially monophasic Salmonella Muenchen), Give (334 isolates, 17.3%), Muenchen (158 isolates, 8.2%), Typhimurium (227 isolates, 11.7%), Oranienburg (106 isolates, 5.5%), and Montevideo (78 isolates, 4%). Sixteen of the 24 most common serovars detected in the region are among the serovars reported to cause the most human salmonellosis in the United States. Some of the serovars were associated with location and seasonal bias. Analysis of Xba I Pulsed Field Gel Electrophoresis (PFGE) patterns of strains of serovars Typhimurium, Oranienburg, and Montevideo showed significant intra-serovar diversity. PFGE pulsotypes were identified in the region for multiple years of the survey, indicating persistence or regular re-introduction to the region. Importance Non-typhoidal Salmonella is the among the leading causes of bacterial foodborne illness and increasing numbers of outbreaks and recalls are due to contaminated produce. High prevalence and 91 different serovars were detected in this leafy green growing region. Seventeen serovars that cause most of the human salmonellosis in the United States were detected, with 16 of those serovars detected in multiple locations and multiple years of the 5-year survey. Understanding the widespread prevalence and diversity of Salmonella in the region will assist in promoting food safety practices and intervention methods for growers and regulators.

scholarly journals Helicopter Pilots Encountering Fog: An Analysis of 109 Accidents from 1992 to 2016

Atmosphere ◽  
2020 ◽  
Vol 11 (9) ◽  
pp. 994
Author(s):  
Alex de Voogt ◽  
Hilary Kalagher ◽  
Andrew Diamond
Keyword(s):  
United States ◽  
Decision Making ◽  
The United States ◽  
Meteorological Conditions ◽  
Transportation Safety ◽  
Online Database ◽  
Fatal Accident ◽  
Instrument Meteorological Conditions ◽  
High Prevalence ◽  
Helicopter Pilots

Helicopters have the ability to make maneuvers or precautionary off-airport landings to avoid flights into instrument meteorological conditions (IMC) such as fog. Flight accidents in which fog was encountered as well as inadvertent and intentional flights into fog were examined to understand their occurrence. A 25-year period in the United States using the National Transportation Safety Board online database was used to collect 109 accident reports of which 73 (67%) were fatal. Pilots flying intentionally into IMC were more likely to be a part of a fatal accident than those who did so inadvertently. Those pilots who were reported as being under pressure when encountering fog conditions were also more likely to be in an accident. The findings confirm a high prevalence and an added danger to intentional flights into IMC. In addition, decision-making under pressure when encountering IMC conditions is now linked to a higher proportion of fatalities, emphasizing that helicopter pilots should be made aware of these specific decision-making circumstances in their operations.

The High Prevalence of Depressive Symptoms and Its Correlates With Older Hmong Refugees in the United States

2019 ◽  
Vol 32 (7-8) ◽  
pp. 660-669 ◽  
Author(s):  
Mai S. Yang ◽  
Jan E. Mutchler
Keyword(s):  
United States ◽  
Depressive Symptoms ◽  
Regression Models ◽  
Later Life ◽  
The United States ◽  
High Risk Population ◽  
Linear Regression Models ◽  
Hopkins Symptom Checklist ◽  
High Prevalence ◽  
Reported Health

Objective: We estimate depressive symptoms in a sample of older Hmong refugees in the United States, and investigate factors shaping risk of depression in this population. Method: Data were collected in California and Minnesota ( N = 127). The study sample included Hmong immigrants aged 55 and over. The measure of depression used is the Hopkins Symptom Checklist–10 (HSCL-10) inventory. Linear regression models were used to identify significant correlates of depressive symptoms. Results: More than 72% of the participants indicated being symptomatic of depression, as reflected by having a HSCL-10 score of 1.85 or higher. Self-reported health was a risk factor for depression. Protective factors from depression were larger household size and older age of arrival into the United States. Discussion: This study updated knowledge about the mental health status of Hmong refugees, who are now at later life. Our findings suggest that depression may be a lifelong experience in this high risk population.

scholarly journals PC192. High Prevalence of Chronic Venous Disease Among Hospital Workers in the United States

2016 ◽  
Vol 63 (6) ◽  
pp. 212S
Author(s):  
Brajesh K. Lal ◽  
Rafael S. Cires-Drouet ◽  
Heather Morris ◽  
John Yokemick ◽  
Matthew Startzel ◽  
...  
Keyword(s):  
United States ◽  
The United States ◽  
Chronic Venous Disease ◽  
Venous Disease ◽  
Hospital Workers ◽  
High Prevalence
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