scholarly journals The Relationship between Body Mass Index (BMI) and Gleason Score of Indonesian Prostate Cancer Men in Hasan Sadikin General Hospital

2018 ◽  
Vol 2 (2) ◽  
Author(s):  
Fauzan Abdurrahman ◽  
Sri Suryanti ◽  
Aaron T Sihombing

The risk of high grade PCa in Asia in relation to BMI had positive or negative effect. The objective of this study is to know the relationship between BMI and Gleason score in Indonesian PCa patients. A cross sectional study was conducted in Hasan Sadikin General Hospital. The data were secondary data taken from medical records of prostate adenocarcinoma patients in Hasan Sadikin General Hospital. Ordinal data were analyzed using Chi square and correlation using Spearman. All calculation was done using SPSS 24. There were 95 Indonesian PCa patients. 78 patients is in normal BMI range. Of those 41 patients (52.6%) is in high level of Gleason score. 17 patients is in high BMI range. High Gleason score was found in 11 patients (P = 0.362; rs = 0.094). Conclusion, there is no relation between BMI in Indonesian PCa and Gleason score.   Keywords : Prostate adenocarcinoma (PCa); BMI; Gleason score.

2019 ◽  
Vol 13 (4) ◽  
pp. 127
Author(s):  
Tjandra Kristiana ◽  
I Gusti Ayu Sri Mahendra Dewi ◽  
Luh Putu Iin Indrayani Maker ◽  
Herman Saputra ◽  
Ni Putu Sriwidyani ◽  
...  

Background: Prostate cancer is the second most common malignancy in men and the fifth most common cause of death worldwide. In Asia, 59.3% of patients come for the advanced stage treatment. PTEN inactivation is identified in about 20% of primary prostate tumors in radical prostatectomy and the loss of PTEN is associated with poor clinical and pathological outcomes. The purpose of this study is to prove that there is an association between PTEN expression and risk grade group Gleason prostate adenocarcinoma in Sanglah Public Hospital, Denpasar.Methods: This is a cross-sectional study. The sample size of this study was 35 paraffin blocks. These samples were selected by proportional stratified random sampling from hematoxylin-eosin preparation. Prostate adenocarcinoma was regrouped into 3 categories based on NCCN risk stratification: low risk grade group Gleason (Gleason score ≤ 6), intermediate risk grade group Gleason (Gleason score 7), and high-risk grade group Gleason (Gleason score 8–10). Immunohistochemistry examination of PTEN was performed and the expression was evaluated by scoring method. The data were analyzed by Chi-square and logistic regression.Results: The analysis result showed that there is an association between PTEN expression and risk grade group Gleason that is statistically significant. The loss of PTEN expression associated with higher risk grade group Gleason is of the higher proportion with p=0.001; PR 3.339; 95% CI: 1.296–8.599, but there is no association between the proportion loss of PTEN expression heterogeneously or homogeneously and the risk grade group Gleason with p=0.742; PR 0.663; 95% CI: 0.179–2.457.Conclusions: This study has proved that PTEN expression is associated with higher risk grade group Gleason prostate adenocarcinoma.


2019 ◽  
Vol 15 (2) ◽  
pp. 139
Author(s):  
Mochamad Ma'roef ◽  
Ayu Prima Kusuma Putri

Prelabor rupture of the membrane (PROM) requires greater attention because of the high prevalence and its tendency to increase. The incidence of PROM at  37 weeks of gestation (aterm) is around 6.45-15.6% and about 2-3 percent of all single preterm pregnancies and 7.4% in twin preterm pregnancies. The purpose of this study was to determine the relationship between leukosituria and the incidence of premature rupture of membrane at < 37 weeks of gestation at the General Hospital of the University of Muhammadiyah Malang during 2015-2017. This is an analytic observational research with a cross-sectional study approach. Data were analyzed with Chi Square. Out of 36 samples that fit in the inclusion criteria, 18 patients had preterm PROM while 18 others had Aterm PROM. PROM mostly occurs in multigravida patients (58.3%, 21 patients). Patients with 38-39 weeks of gestation had the highest prevalence of PROM. Out of 18 Preterm PROM patients, 9 patients had leukocyturia. Only 1 aterm patients had positive leukocyturia. The result of this study showed a significant relationship between the incidence of PROM and preterm pregnancy.


2019 ◽  
Vol 7 (2) ◽  
pp. 115
Author(s):  
Dini Yuliansari

The well is one of the source water used for bathing, washing, and drinking by the citizens in Jiken Hamlet, Rarang Village, Terara Sub-District. Poor dug well construction conditions can affect the amount of coliform bacteria contained in the dug well water. The purpose of this study is to identify the construction of dug wells and the content of coliform bacteria in dug well water and determine the relationship between dug well construction and the content of coliform bacteria. This research is analytic with a cross sectional study design. The results were obtained from 11 samples of dug wells which were observed in construction and the coliform content was known that all samples did not requirements as good dug well construction. Coliform content test results showed that as many as 5 dug well water samples did not pass the clean water quality standards. The results of data analysis with the chi-square test variable construction of dug wells with coliform content variable  showed 0,172 > 0,05, then the concluded is the dug well not suitable to use by people in that area as a source of water for daily needs.


2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
L Wolvaardt ◽  
R Nemuntandani ◽  
I Kamungoma-Dada

Abstract Background Access to essential medicines in South Africa has been compromised by stockouts in health facilities. This study describes the occurrence of stockouts for a selection of essential medicines. Methods This cross-sectional study used secondary data retrieved from the Stop Stock Outs Project (SSP). A descriptive analysis was conducted on data from the 2013-2015 SSP case management database of routinely reported stockouts. Chi square tests of independence was conducted on data from the SSP 2015 annual telephonic survey to investigate associations between the occurrence of stockouts, the level of health facility and the type of health professional. Results 231 facilities reported 609 stockouts. Antiretroviral medication had the most stockout reports (78%; n = 475/609), followed by anti-infectives (17.1%; n = 104/609) and tuberculosis medication (4.9%; n = 30/609). The highest number of stockout reports were received from Gauteng province and the majority (71.09%; n = 150/211) of facilities reporting stockouts were in urban areas. There were more stockouts at ambulatory, rather than inpatient care, facilities however, this was not statistically significant. Conclusions This study confirms that South Africa experiences medicine stockouts for many of the essential medicines, with antiretroviral medication being the category most affected. The stockouts vary between provinces and the urban-rural divide but are an equal threat to both ambulatory and inpatient facilities. Key messages The pattern of stockouts experienced over a three-year period suggest that stockouts are ‘normal’ despite the substantive effects of treatment interruption – especially patients with HIV and/or TB. Antiretroviral therapy is at risk as a result of stockouts.


2021 ◽  
Vol 3 (2) ◽  
pp. 48-58
Author(s):  
Ajeng Febrianti Rahayu ◽  
Bagas Aidi ◽  
Meirna Mega Rizki ◽  
Ayik Mirayanti Mandagi

ABSTRACTFirst year student are one of the groups that are prone to depression. This is because the first year student is in a transition period or in a new condition that initially senior high school student becomes a college student. In addition, busy schedules, new learning environments and homesickness can trigger depression in college students. This study used a cross sectional study design. Respondents in this study were new students of the Study Program Outside the Main Campus (PSDKU) of Airlangga University in Banyuwangi, class 2019 with a total of 110 students. Depression levels were obtained from the Beck Depression Inventory (BDI-II) questionnaire. Meanwhile, the adaptability was obtained from the Communicative Adaptability Scale (CAS) questionnaire and the place of residence was obtained from questions about where to live during college. A total of 53 out of 110 students (49,1%) experienced low depression and students who experienced high depression were 57 out of 110 students (50,9%). The results of the chi square test regarding the relationship between residence and the level of depression of new students, obtained data p= 0.008 (p <0.05). Chi-square test results regarding the relationship between adaptation ability and depression level of new students, obtained data p = 0.001 (p <0.05). There is a relationship between residence and adaptability with the degree of depression of new students. Higher education institutions are expected to pay more attention to the psychological conditions of students and new students are expected to maintain good coping management in facing the new environment.Keywords: depression level, adaptability, place to live, new students ABSTRAKMahasiswa baru adalah salah satu kelompok yang rentan mengalami depresi. Hal ini dikarenakan mahasiswa baru berada pada masa transisi atau suatu kondisi baru yang awalnya siswa SMA menjadi mahasiswa. Selain itu, jadwal yang padat, lingkungan belajar yang baru dan homesickness dapat memicu depresi pada mahasiswa. Penelitian ini menggunakan desain penelitian crosssectional. Responden pada penelitian ini yaitu mahasiswa baru Program Studi Diluar Kampus Utama (PSDKU) Universitas Airlangga di Banyuwangi angkatan 2019 dengan jumlah 110 mahasiswa. Tingkat Depresi didapatkan dari kuisioner Beck Depression Inventory (BDI-II). Sedangkan kemampuan adaptasi didapatkan dari kuisioner Communicative Adaptability Scale (CAS) dan tempat tinggal didapatkan dari pertanyaan mengenai tempat tinggal selama kuliah. Sebanyak 49,1% (53 dari 110 mahasiswa) mengalami depresi ringan dan mahasiswa yang mengalami depresi berat sebanyak 50,9 (57 dari 110 mahasiswa). Hasil uji chisquare mengenai hubungan tempat tinggal dengan tingkat depresi mahasiswa baru, diperoleh data p=0,008 (p<0,05). Hasil uji chisquare mengenai hubungan kemampuan adaptasi dengan tingkat depresi mahasiswa baru, diperoleh data p=0,001(p<0,05). Terdapat hubungan antara tempat tinggal dan kemampuan adaptasi dengan tingkat depresi mahasiswa baru. Institusi perguruan tinggi diharapkan lebih memperhatikan kondisi psikologis mahasiswa dan mahasiswa baru diharapkan tetap mempertahankan manajemen koping yang baik dalam menghadapi lingkungan baru.Kata Kunci: tingkat depresi, kemampuan adaptasi, tempat tinggal, mahasiswa baru


Author(s):  
Dyah Widiastuti ◽  
Dwi Priyanto

Leptospirosis is associated with occupations which exposed workers to contaminated environments. The risk of leptospirosis exposure in the market as a gathering place for many people needs to be assessed, to obtain the basis for decision making to anticipate leptospirosis transmission. This study aimed to determine the relationship between market environmental conditions including market sanitation conditions, the level of rat density and the presence of leptospira-positive rats  toward the history of leptospirosis exposure among market workers (traders and janitors). A cross sectional study conducted in 35 markets in Banjarnegara and 175 market workers randomly selected. Blood samples analysed using ELISA against 40 Kda pathogenic Leptospira protein. Rat trapping  conducted in each market for two days with 100 traps. The caught mice examined with Polymerase Chain Reaction (PCR) to detect the presence of Leptospira bacteria in their kidneys. Leptospirosis exposure was spread in 17 markets in Banjarnegara. The PCR examination showed that the pathogenic Leptospira infected rats were spread in four markets in Banjarnegara. Chi square test showed that the hygene condition in market area was significantly associated with the leptospirosis exposure. Markets workers (traders and janitors) were at risk for leptospirosis proved by high seroprevalence of leptospirosis in this study.


2021 ◽  
Vol 1 (1) ◽  
pp. 7
Author(s):  
Vivienne Tjung ◽  
Husnia Auliyatul Umma ◽  
Jarot Subandono

<p class="16"><strong><em>Introduction</em></strong><strong><em>:</em></strong><strong><em> </em></strong><em>Exclusive breast milk is breastfeeding for six months to babies, without providing other foods and drinks. Breastfeeding for up to 6 months is recommended by various health organizations, including the Ministry of Health. In Indonesia, exclusive breastfeeding is still low, even though the benefits of breastfeeding are numerous. Various studies that have been conducted have shown </em><em>different</em><em> results regarding the relationship between the number and sequence of children with breastfeeding practices. This stud</em><em>y </em><em>aimed</em><em> </em><em>to determine the relationship between the number of children and the order of the children with the practice of exclusive breastfeeding in Surakarta</em><em></em></p><p class="16"><strong><em>Methods</em></strong><strong><em>:</em></strong><strong><em> </em></strong><em>This study </em><em>was</em><em> an analytic observational study with a cross-sectional study design. The research sample was determined by random sampling of mothers registered at the Penumping Health Center. The research sample consisted of 50 people who have children aged 1-5 years. Assessment of completeness of breastfeeding was measured using a questionnaire. Data were analyzed using bivariate analysis techniques using chi-square and multivariate logistic regression</em><em>.</em><em></em></p><p class="16"><strong><em>Result</em></strong><strong><em>s and discussions: </em></strong><em>From</em><em> 47</em><em> </em><em>subjects studied with the bivariate analysis technique using the chi square between the number of children and the order of children with exclusive breastfeeding practice, the results were less significant, p = 0.724 and p = 0.401</em><em>.</em><em></em></p><p class="16"><strong><em>Conclusion</em></strong><strong><em>: </em></strong><em>There </em><em>was</em><em> no significant relationship between the number of children and the order of children with the practice of exclusive breastfeeding in Surakarta.</em><em></em></p><p class="18"><strong><em>Keywords</em></strong><strong><em>: </em></strong><strong><em>E</em></strong><strong><em>xc</em></strong><strong><em>lusive breastfeeding, number of children, </em></strong><strong><em>order </em></strong><strong><em>of children</em></strong><strong><em>.</em></strong><strong><em></em></strong></p>


CommonHealth ◽  
2021 ◽  
Vol 2 (3) ◽  
pp. 85-93
Author(s):  
Aaron Houston MPH ◽  
Joseph Ruskiwewicz ◽  
John Gaal MHA ◽  
Chaitali Baviskar MHSA ◽  
Atiya Latimer

 The purpose of  this study was to identify associations between insurance type and costs and to investigate specified variables’ influence on individuals’ access to adequate coverage. This was a cross sectional study, using secondary data analyses. The study was completed at The Eye Institute (TEI) East Oak Lane Campus in Philadelphia, PA. The study population was all patients seen at TEI East Oak Lane Campus, specifically patients seen at TEI clinic from January 1st, 2019, - to December 31st, 2019, whose encounter generated an insurance claim (n=68,484). The exposure was insurance type and outcomes were patient total amount, billed amount, and pay amount by patient. Data analyses were performed using SAS, version 9.4. In all statistical analyses, p-values were one-sided and considered statistically significant if 0.05 or lower. The study protocol was approved by the Institutional Review Boards of Salus University. The sample represented an older population with an average age of about 55. There was a significant association found between financial class with patient total amount (p<0.0001), billed amount(p<0.0001), and pay amount (p<0.0001). People with managed PPO pay the least, while those on Medicaid and workers compensation pay the most out of pocket. The two Philadelphia zip codes which pay the most out of pocket have two of the lowest average household incomes in the Greater Philadelphia area. Insurance type and out of pocket expenses potentially have a negative effect on patient vision health and affordability of care as well as access to care. These findings contribute to the identification of variables that influence individual’s healthcare accessibility and evidence for opportunities to improve insurance coverage.            


2021 ◽  
Vol 10 (1) ◽  
pp. 72
Author(s):  
Melvanda Gisela Putri ◽  
Roedi Irawan ◽  
Indri Safitri Mukono

ABSTRAKLatar Belakang: Stunting merupakan suatu istilah yang menggambarkan kondisi pertumbuhan tinggi badan kurang berdasarkan umur disesuaikan dengan Z-Score (<-2SD). Stunting pada balita dapat diakibatkan oleh kurangnya asupan zat gizi yang diperlukan bagi pertumbuhan anak. Penelitian dilakukan untuk mengetahui hubungan suplementasi vitamin A, pemberian imunisasi dan riwayat penyakit infeksi yakni diare dan ISPA terhadap kejadian stunting.Tujuan: Mengetahui hubungan suplementasi vitamin A, pemberian imunisasi, dan penyakit infeksi terhadap stunting pada anak usia 24-59 bulan di Puskesmas Mulyorejo, Surabaya.Metode: Penelitian ini merupakan penelitian analitik observasional dengan metode cross sectional. Besar sampel adalah 107 anak usia 24-59 bulan di Puskesmas Mulyorejo, Surabaya. terdiri dari 25 anak kelompok stunting dan 82 anak kelompok non- stunting. Cara pengambilan data melalui data sekunder posyandu dan wawancara langsung orang tua anak dengan pengisian kuisioner. Data dianalisis menggunakan uji Chi-Square, Fisher Exact, dan Mann Whitney.Hasil: Penelitian ini menunjukkan hasil terdapat hubungan suplementasi vitamin A dengan stunting (p=0,000), tidak ada hubungan antara pemberian imunisasi terhadap stunting (p=0,332). Dalam riwayat penyakit infeksi, frekuensi diare dan ISPA ditemukan tidak ada hubungan dengan  stunting (p=0,053 dan p=0,082), begitu pula pada lama diare dan lama ISPA tidak berhubungan dengan stunting (p= 0,614 dan p=0,918).Kesimpulan: Suplementasi vitamin A berhubungan signifikan dengan stunting yang diamati pada anak usia 24-59 bulan di Puskesmas Mulyorejo, Surabaya. Kata kunci: kejadian stunting, vitamin A, imunisasi, penyakit infeksi, anak usia 24-59 bulanABSTRACTBackground: Stunting is a term that describes condition of lower height-for-age Z-Score (<-2SD). Stunting among children can be caused by a lack of nutrients needed for children's growth. This study was conducted to determine the relationship between vitamin A supplementation, immunization and a history of infectious diseases, namely diarrhea and ARI to the incidence of stunting.Objectives: To determine the relationship between vitamin A supplementation, immunization, and history of infectious disease with the incidence of stunting in children aged 24-59 months at Puskesmas Mulyorejo, Surabaya.Methods: This study was an observational analytic study with cross sectional method. The sample size was 107 children aged 24-59 months at Puskesmas Mulyorejo, Surabaya. This study consisted of 25 children in the stunting group and 82 children in the non-stunting group. The method of data collection was through secondary data from posyandu and direct interviews with parents by filling out questionnaires. Data were analyzed using the chi-square test, fisher exact, and Mann Whitney.Results: The results of this study indicated that there was a relationship between vitamin A supplementation and with stunting (p = 0.000). There was no relationship between immunization and stunting (p = 0.332). In the history of infectious diseases, the frequency of diarrhea and ARI was found to have no relationship with stunting (p = 0.053 and p = 0.082), as well as the duration of diarrhea and duration of ARI there was no association with the stunting (p = 0.614 and p = 0.918).Conclusion: Vitamin A supplementation has significant relationship with stunting in children aged 24-59 months at Puskesmas Mulyorejo, Surabaya.


2017 ◽  
Vol 4 (2) ◽  
pp. 176
Author(s):  
Aminatul Fitria

Cataract is the leading cause of 51% blindness case in the world. Cataract can only be cured trough surgery, but most people with cataract in Indonesia is not in undergoing surgery due to several factors. The increasing number of cataract victim whose not undergoing any treatment to cure them will resulting in increasing number of blindness case, so blindness cause by cataracts can be a public health problem. This research was conducted to determine the relationship of age, attitudes, knowledge and the cost of the action to perform cataract surgery. This research was an observational analytic study with cross sectional design. The samples were cataract patients in Undaan Eye Hospital Surabaya who were randomly selected using a simple random sampling based on medical records of 60 people. Data collection was done by taking secondary data and interviews to patients. Those variables was analyzed with chi square or Fisher’s exact with significancy level at 95%. The result showed that there were correlation between knowledge (p = 0.017), operating costs (p = 0.001) and attitude (0.000) while age was not related (p = 1.000), the actions to perform cataract surgery. The conclusion from this research was the attitude, knowledge and operating costs related to the actions to perform cataract surgery, while age was not related to the actions to perform cataract surgery. It is recommended to give through leaflets or other media in the lobby for improving patient education, counseling to the patient family, the doctor’s advice to convince patient for surgery.Keywords: practice, surgery, cataract, attitudes, costs


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