RISING DOMESTIC VIOLENCE DURING EMERGENCIES AND THE COVID-19 PANDEMIC

2021 ◽  
pp. 111-123
Author(s):  
Tamara K. Rostovskaya ◽  
◽  
Natal’ya A. Bezverbnaya ◽  
Keyword(s):  
Domestic Violence ◽  
World Health ◽  
Main Body ◽  
Scientific Publications ◽  
Non Profit ◽  
Emergency Situations ◽  
Quantitative And Qualitative Research ◽  
The Usa ◽  
Health Organization ◽  
Restrictive Measures

The issue of the situation of women facing domestic violence in emergency situations, including the environmental and man-made disasters, pandemics, in general, remains poorly understood. The main body of scientific publications on the topic is represented by quantitative and qualitative research conducted in Australia, Canada, New Zealand, and the USA. Several important events have taken place in the Russian Federation over the past few years, which, in our opinion, have aggravated the issue of domestic violence: firstly, cessation of the statistical recording of offenses related to beating the family members and other close persons, therefore, the main data were obtained by the authors from non-profit organizations that provide assistance to victims of domestic violence. The second event that affected every country and territory is the COVID-19 pandemic: the first and second waves of the pandemic entailed restrictive measures, which provoked socio-economic tensions in isolation. The COVID-19 pandemic is classified as a public health emergency of international concern by the World Health Organization Declaration. In that context, the issue of the risks of domestic violence is of particular relevance

scholarly journals Squamous cell carcinoma mimics small cell carcinoma of the lung: a case report

2020 ◽  
Vol 2020 (12) ◽  
Author(s):  
Michael Kmeid ◽  
Breanne Gillie ◽  
Armand Asarian ◽  
Philip Xiao
Keyword(s):  
Cell Carcinoma ◽  
Small Cell Carcinoma ◽  
Squamous Cell ◽  
Lung Tumors ◽  
Small Cell ◽  
World Health ◽  
Lung Cancers ◽  
Lung Carcinomas ◽  
The Usa ◽  
Health Organization

Abstract Squamous cell carcinomas (SCC) accounts for roughly 20% of lung cancers in the USA. The 2015 World Health Organization classification of lung tumors further categorizes SCC as three subtypes: keratinizing, non-keratinizing and basaloid variant. The non-keratinizing subtype is a poorly differentiated tumor that can present histologically in different ways, and one of which is a rare variant that strongly resembles small cell carcinoma. As a result, histological diagnosis alone is not sufficient to properly diagnose lung carcinomas. Immunohistochemistry has been increasingly used over the past few years to differentiate between lung tumors. The combination of morphological and immunohistochemical staining should be the mainstay for diagnosis of all lung carcinomas as more targeted therapies become more available.

Reflections on FDA and WHO recommendations concerning clinical trials

1989 ◽  
Vol 4 (2) ◽  
pp. 117-122 ◽  
Author(s):  
J.-F. Dreyfus ◽  
D. Cremniter ◽  
J.D. Guelfi
Keyword(s):  
Clinical Trials ◽  
Drug Users ◽  
Objective Evaluation ◽  
World Health ◽  
Measuring Instruments ◽  
New Techniques ◽  
The Usa ◽  
The One ◽  
Health Organization

SummaryWe are still confronted by numerous different nosographic models and problems concerning the objective evaluation of patients progress during treatment. It is interesting to consider the consequences of this situation in psychiatry which still involves a relative diversity of practical methods used in clinical trials. The recommendations of the USA Food and Drug Administration, on the one hand, constitute a highly structured and precise reference. The World Health Organization, on the other hand, promulgates general recommendations resulting from a compromise designed to satisfy the greatest number of clinicians.Despite the apparently diverse principles and the different practical methods they propose, both those sets of recommendations have been useful in inspiring clinicians to reflect upon these different methodological approaches. The qualities of the inclusion criteria used in the study of patients and the sensitivity of the different measuring instruments have allowed psychotropic drug users as well as producers to recognize the need for a certain rigour in clinical trials.The FDA and WHO guidelines have certainly improved the quality of clinical trials in psychopharmacology. However, they also represent a source of resistance to innovation.A series of consensus meetings to first reconcile US and European points of view and later to include new techniques in the recognized sets of methods would therefore be helpful.

scholarly journals Importance of immunoglobulin therapy for COVID-19 patients with lymphocytopenia

2021 ◽  
Vol 45 (1) ◽  
Author(s):  
Heba K. Nabih
Keyword(s):  
Passive Immunization ◽  
Immunoglobulin Therapy ◽  
World Health ◽  
Clinical Feature ◽  
Main Body ◽  
Plasma Therapy ◽  
Rapid Spread ◽  
The World ◽  
Health Organization

Abstract Background The global coronavirus disease 2019 (COVID-19) was announced as pandemic by the World Health Organization (WHO). With the increased number of infected and dead victims daily all over the world, it becomes necessary to stop or overcome its rapid spread. Main body Although the production of vaccine or even specified effective anti-virus may take about six months to a year, intravenous immunoglobulin (IVIg) may be clinically used as a safe treatment to save and improve the quality of life of patients with a variety of immunodeficiency diseases such as lymphocytopenia, which is a common clinical feature in COVID-19. Conclusion Through the current review, it was concluded that this passive immunization may promote the immunity to better fight against the virus, so the survival of the patients could be kept longer. The efficacy of immunotherapy with IVIg would be greater if the immune IgG antibodies were collected from convalescent plasma therapy.

scholarly journals Antibiotic Pipeline Coordinators

2018 ◽  
Vol 46 (S1) ◽  
pp. 25-31 ◽  
Author(s):  
Enrico Baraldi ◽  
Olof Lindahl ◽  
Miloje Savic ◽  
David Findlay ◽  
Christine Årdal
Keyword(s):  
Research And Development ◽  
World Health ◽  
Resistant Bacteria ◽  
Antibiotic Resistant ◽  
Priority List ◽  
Non Profit ◽  
Global Priority ◽  
The World ◽  
New Antibiotics ◽  
Health Organization

The World Health Organization (WHO) has published a global priority list of antibiotic-resistant bacteria to guide research and development (R&D) of new antibiotics. Every pathogen on this list requires R&D activity, but some are more attractive for private sector investments, as evidenced by the current antibacterial pipeline. A “pipeline coordinator” is a governmental/non-profit organization that closely tracks the antibacterial pipeline and actively supports R&D across all priority pathogens employing new financing tools.

scholarly journals Strengths and weaknesses of the Brazilian regulation on biosimilars: A critical view of the regulatory requirements for biosimilars in Brazil

2018 ◽  
Vol 10 (12) ◽  
pp. 253-259 ◽  
Author(s):  
Marcos Renato de Assis ◽  
Valdair Pinto
Keyword(s):  
Conflicts Of Interest ◽  
Expression System ◽  
World Health ◽  
Regulatory Requirements ◽  
Biological Products ◽  
Synthetic Drugs ◽  
Comparability Exercise ◽  
The Face ◽  
The Usa ◽  
Health Organization

Biological products or biopharmaceuticals are medicinal products derived from living systems and manufactured by modern biotechnological methods that differ widely from the traditional synthetic drugs. Monoclonal antibodies are the most rapidly growing type of biologic. They are much larger and more complex molecules with inherent diversity; therefore, different manufacturers cannot produce identical biological products, even with the same type of host expression system and equivalent technologies. Thus, legal follow-on biologics manufactured and marketed after patent expiration are usually referred to as biosimilars. Biosimilarity is based on a comparability exercise whereby unavoidable clinical differences are evaluated and must meet equivalence or non-inferiority criteria. Biosimilars need to comply with different regulatory requirements for market authorization in different sites. There are several other related issues that need to be defined by the national authorities, such as interchangeability, labeling and prescribing information. The Brazilian health surveillance agency follows the key principles established by the World Health Organization for the assessment of biosimilarity, although does not adopt the name ‘biosimilar’. However, the agency also made a compromise on a standalone application pathway that does not require the usual comparability exercise with the reference product, originating nonbiosimilar copies. Interchangeability and the use of nonproprietary names are not regulated, giving rise to pressures on physicians and conflicts of interest in the decision making on biosimilar use. The scope of this article is to present the Brazilian regulation on biosimilars, its strengths and weaknesses, and to discuss it in the face of regulations in the USA and Europe.

scholarly journals Analysis of the Research Hotspot of Drug Treatment of Tuberculosis: A Bibliometric Based on the Top 50 Cited Literatures

2022 ◽  
Vol 2022 ◽  
pp. 1-17
Author(s):  
Ying Xiong ◽  
Jingwen Wei ◽  
Yujia Cai ◽  
Yang Zhang ◽  
Li Feng ◽  
...  
Keyword(s):  
Drug Treatment ◽  
New England ◽  
Web Of Science ◽  
World Health ◽  
Future Research ◽  
First Line ◽  
Resistant Tuberculosis ◽  
The Usa ◽  
Health Organization ◽  
Study Type

Objective. The objective of the current study was to analyze the research hotspot of drug treatment for tuberculosis via top literatures. Materials and Methods. A retrospective analysis was performed on June 7th, 2021. Literatures were searched on the Web of Science Core Collection to identify the top 50 cited literatures related to drug treatment of tuberculosis. The characteristics of the literatures were identified. The outcomes included authorship, journal, study type, year of publication, and institution. Cooccurrence network analysis and visualization were conducted using the VOS viewer (Version 1.6.16; Leiden University, Leiden, The Netherlands). Results. The top 50 cited literatures were cited 308 to 2689 times and were published between 1982 and 2014. The most studied drugs were the first-line drugs such as isoniazid and rifampicin ( n = 22 ), and drug-resistant tuberculosis was most frequently reported ( n = 16 ). They were published in 18 journals, and the New England Journal of Medicine published the most literatures ( n = 18 ), followed by the American Journal of Respiratory and Critical Care Medicine ( n = 7 ), and the Lancet ( n = 6 ). The authors were from 13 countries, and the authors from the USA published most of the literatures ( n = 30 ), while authors from other countries published less than five literatures. The CDC in the USA ( n = 4 ), the World Health Organization (WHO) ( n = 3 ), and the American Philosophical Society ( n = 3 ) were the leading institutions, and only two authors published at least two top-cited literatures as first authors. Conclusions. This study provides insights into the development and most important literatures on drug therapy for tuberculosis and evidence for future research on tuberculosis treatment.

scholarly journals A comparative analysis of world health systems and Covid-19

2021 ◽  
Vol 38 (2) ◽  
pp. 115-120
Author(s):  
Ayşe İKİNCİ KELEŞ ◽  
Gökhan KELEŞ
Keyword(s):  
Health Systems ◽  
Social Life ◽  
Meta Analysis ◽  
Good Health ◽  
The United States ◽  
World Health ◽  
The Face ◽  
The Usa ◽  
Health Organization ◽  
Second Wave

Coronavirus disease 2019 (COVID-19), which causes severe airway problems, first emerged in the Chinese city of Wuhan. The virus led to a pandemic that affected the entire world. COVID-19 affects not only health, but also economic and social life. The emergence of this pandemic has led to health systems across the world being questioned. The aim of this study was to assess the adequacy of world health systems in the face of this pandemic. Twelve countries were selected and analyzed in the study. The choice of these countries was determined by the number of COVID-19 cases and deaths. Information concerning health systems and COVID-19 was obtained from Organization for Economic Co-operation and Development 2018, World Health Organization 2020 and Deep Knowledge Group data and was subjected to statistical analysis. According to the analysis, the country with the highest investment in health expenditures is the United States (10586 US dollars/capita), and Germany stands out as the best in health services. Another finding is the first and second wave of COVID-19 was identified as the USA with the highest case and death rate (First wave cases 1.942.363 and deaths 110.514; second wave cases at 7.419.230 and deaths 2.09.450). As a result of the meta-analysis, it is revealed that only socio-economic power is not enough, countries with good health systems are more successful in the pandemic. In addition, the analysis once again reveal how important health systems are in the face of such a pandemic.

scholarly journals A International standards and rules for interaction between public authori-ties during the Covid-19 pandemic

2021 ◽  
Vol 7 (Extra-D) ◽  
pp. 480-490
Author(s):  
Tatyana Viktorovna Gololobova ◽  
Salavat Khamitovich Sarmanaev ◽  
Sergey Zenin ◽  
Aleksey Yuryevich Shirokov ◽  
Georgiy Nikolaevich Suvorov
Keyword(s):  
International Standards ◽  
World Health ◽  
Federal State ◽  
Public Authorities ◽  
The Core ◽  
Special Scientific ◽  
Legal Model ◽  
The Usa ◽  
Health Organization ◽  
Rules And Standards

The study aims at identifying the core rules and standards for forming a legal model of inter-action between levels of public authority in a federal state during a pandemic. The authors have considered documents that regulate the process of interaction between public authorities during the coronavirus pandemic, as well as the doctrinal sources of law in Belgium, Germany, Canada, the USA, Switzerland, and Australia. In addition, they have analyzed the acts of the World Health Organization adopted during the COVID-19 epidemic and containing recom-mendations on the interaction of public authorities during a pandemic. The research methods were as follows: general philosophical, general and special scientific (structural-legal, compara-tive-legal, and formal-legal The authors have concluded that it is possible to introduce separate rules and standards for such interaction of public authorities during the period of a pandemic into the Russian legal system.

scholarly journals Environmental and health impacts of spraying COVID-19 disinfectants with associated challenges

2021 ◽  
Author(s):  
Shakeel Ahmad Bhat ◽  
Farooq Sher ◽  
Rohitashw Kumar ◽  
Emina Karahmet ◽  
Syed Anam Ul Haq ◽  
...  
Keyword(s):  
International Committee ◽  
World Health ◽  
Disease Spread ◽  
Secondary Products ◽  
Global Pandemic ◽  
Specific Morphology ◽  
Application Techniques ◽  
The Usa ◽  
Health Organization ◽  
Chemical Usage

AbstractCoronavirus refers to a group of widespread viruses. The name refers to the specific morphology of these viruses because their spikes look like a crown under an electron microscope. The outbreak of coronavirus disease 2019 (COVID-19) that has been reported in Wuhan, China, in December 2019, was proclaimed an international public health emergency (PHEIC) on 30 January 2020, and on 11 March 2020, it was declared as a pandemic (World Health Organization 2020). The official name of the virus was declared by the WHO as “COVID-19 virus”, formerly known as “2019-nCoV”, or “Wuhan Coronavirus”. The International Committee on Virus Taxonomy’s Coronavirus Research Group has identified that this virus is a form of coronavirus that caused a severe outbreak of acute respiratory syndrome in 2002–2003 (SARS). As a result, the latest severe acute respiratory syndrome has been classified as a corona virus 2 (SARS-CoV-2) pathogen by this committee. This disease spread quickly across the country and the world within the first 3 months of the outbreak and became a global pandemic. To stop COVID-19 from spreading, the governing agencies used various chemicals to disinfect different commercial spaces, streets and highways. However, people used it aggressively because of panic conditions, anxiety and unconsciousness, which can have a detrimental impact on human health and the environment. Our water bodies, soil and air have been polluted by disinfectants, forming secondary products that can be poisonous and mutagenic. In the prevention and spread of COVID-19, disinfection is crucial, but disinfection should be carried out with sufficient precautions to minimize exposure to harmful by-products. In addition, to prevent inhalation, adequate personal protective equipment should be worn and chemical usage, concentrations, ventilation in the room and application techniques should be carefully considered. In the USA, 60% of respondents said they cleaned or disinfected their homes more often than they had in the previous months. In addition to the robust use of disinfection approaches to combat COVID-19, we will explore safe preventative solutions here.

scholarly journals Comunicando el Cambio Climático desde un Encuadre de Salud = Communicating Climate Change from a Health Frame

2018 ◽  
Vol 9 (1) ◽  
pp. 99
Author(s):  
José Daniel Cáceres Pinto
Keyword(s):  
Climate Change ◽  
International Organizations ◽  
Water Distribution ◽  
World Health ◽  
Success Story ◽  
Social Actors ◽  
Raising Awareness ◽  
The Usa ◽  
Health Organization ◽  
The Impact

Resumen: Organismos internacionales coinciden que el cambio climático representa una amenaza para el ser humano, particularmente para su salud. Entidades como la Organización Mundial de la Salud (OMS) y voces de la comunidad científica han venido advirtiendo sobre los efectos que las distor­siones climáticas están teniendo sobre la propagación de enfermedades cuyos vectores dependen de su entorno. Sectores vitales para el desarrollo social como la distribución del agua, la agricultu­ra, y la sanidad pública se están viendo cada vez más amenazados por la vorágine climatológica. Sin embargo, persiste una indiferencia silenciosa en diferentes segmentos sociales que consideran el Cambio Climático como un problema abstracto o simplemente algo muy sobre sus capacidades de resolución. Desactivar este desafecto, concienciar a la población general y movilizar a la toma de acción han sido unos de los retos que diversos actores sociales han asumido. Uno de los casos de éxito que más llama la atención ha sido el uso de encuadres de salud. El siguiente artículo di­secciona el impacto que el Cambio Climático tiene y presenta el caso sobre el uso de la promoción de la salud en EEUU para concienciar sobre la problemática ambiental.Palabras clave: Salud; Cambio Climático; encuadres; mensaje.Abstract: International organizations agree that climate change poses a threat to the human being, parti­cularly to his health. Entities such as the World Health Organization (WHO) and voices from the scientific community have been warning about the effects the climatic distortions are having on the propagation of illnesses which vectors depend on their surroundings. Vital sectors for social development such as water distribution, agriculture, and public health are progressively seeing themselves more threatened by the climatic maelstrom. Nevertheless, an indifferent silence per­sists in different social segments who consider Climate change as an abstract problem or simply something out of their reach to resolve. Deactivating this disaffection, raising awareness in the ge­neral population and mobilize to take action have been some of the challenges social actors have undertaken. One particular success story that grabs the attention is the use of health frames. The following article dissects the impact that Climate Change has and presents the case of the use of health promotion in the USA to raise awareness about the environmental problem.Keywords: Health; Climate Change; Frames; Message.

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