Prevalence of hypovitaminosis D in the adult population of the Republic of Belarus

Hypovitaminosis D in both adults and children is detected with high frequency in various geographic zones of our planet. At the same time, vitamin D has a number of positive effects on human health and is an important micronutrient for prevention of some diseases. The purpose of this study is to identify the incidence of vitamin D deficiency and insufficiency in the adult population of the Republic of Belarus. We analyzed the laboratory results on total vitamin D that was produced in 2019 and 2020 in persons over 18 years old living in the Republic of Belarus. The vitamin D status was assessed according to international guidelines. The average level of vitamin D in the surveyed population during the study period did not reach normal values in all age groups in both men and women. The highest frequency of hypovitaminosis D was observed in the autumn-winter period and reached 81.6 % in January 2019 and 77.8 % in January 2020. In the summer months, normal levels of vitamin D were observed in less than 50 % of those surveyed: the maximum values were 40.7 % in July 2019 and 45.8 % in July 2020. Due to the high prevalence of hypovitaminosis D, it is advisable to carry out measures for prevention and treatment of DVD in the residents of the Republic of Belarus at the population level.

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A study on vitamin D status among orthopaedic patients

International Journal of Research in Orthopaedics ◽

10.18203/issn.2455-4510.intjresorthop20200036 ◽

2020 ◽

Vol 6 (2) ◽

pp. 286

Author(s):

Srinivasalu Santhanagopal ◽

Matthew Sebastian ◽

Madan Mohan Muniswamy ◽

Anoop Pilar

Keyword(s):

Vitamin D ◽

Vitamin D Deficiency ◽

Indian Population ◽

Age Groups ◽

Hypovitaminosis D ◽

Vitamin D Status ◽

Orthopaedic Patients ◽

Vitamin D Levels ◽

High Prevalence ◽

Calcium Phosphorus

Background: There is an alarmingly high prevalence of hypovitaminosis D in orthopaedic patients, regardless of whether or not, they require surgical intervention. Vitamin D plays an essential role in bone formation, maintenance, and remodelling, as well as muscle function and deficiency could affect adversely in multiple ways. Many reports recently demonstrated high rates of vitamin D deficiency, in numerous segments of Indian population, but there is no study reported so far from India, which focuses specifically on vitamin D status in orthopaedic patients.Methods: It is a descriptive study to estimate vitamin D levels in patients scheduled to undergo orthopaedic surgery. Vitamin D, calcium, phosphorus and alkaline phosphatase (ALP) levels in 310 patients, who were admitted at our institution, from December 2015 to August 2017 were measured.Results: Out of 310 patients included in our study, 189 (61%) were males and 121 (39%) females. Vitamin D deficiency (<20 ng/ml) was present in 232 patients, insufficiency (<30 ng/ml) was present in 63 patients and only 15 patients had desirable levels (>30 ng/ml). Patients younger than 60 years and males had more prevalence of Vitamin D abnormality. 168 (72.4%) of the patients, with deficiency presented in winter, compared to 64 (27.6%) in summer.Conclusions: Statistically significant vitamin D deficiency was seen during winter months, in patients undergoing hip hemiarthroplasty, and in patients admitted for degenerative disease of the spine, hip and knee. Screening and treating hypovitaminosis D appears to be important in orthopaedic patients as vitamin D deficiency is prevalent across all age groups in the population studied.

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The Prevalence of Vitamin D Deficiency in Iran: A Literature Review

Current Nutrition & Food Science ◽

10.2174/1573401316666200123100453 ◽

2020 ◽

Vol 16 (7) ◽

pp. 1015-1027

Author(s):

Mohammad Bagherniya ◽

Zahra Khorasanchi ◽

Mina S. Bidokhti ◽

Gordon A. Ferns ◽

Mitra Rezaei ◽

...

Keyword(s):

Vitamin D ◽

Literature Review ◽

Vitamin D Deficiency ◽

Medical Condition ◽

Scientific Information ◽

Age Groups ◽

Public Health Problem ◽

Major Public Health Problem ◽

Vitamin D Levels ◽

High Prevalence

Background: Vitamin D deficiency is a common medical condition worldwide. In Iran, it has been reported that between 30-90% of people have vitamin D deficiency. However, its distribution in different parts of the country and among different age and regional groups is unclear. Therefore, the aim of this study was to review the recent literature on vitamin D deficiency in Iran. Methods: The literature review was performed using Web of Science, PubMed-Medline, Scopus and Scientific Information Database (SID) with a cut-off date of November 2016 to identify articles on vitamin D status in Iran published in the last 10 years. Studies in English and Persian that reported vitamin D levels in male and female subjects of all age groups and in healthy populations were included. Results: From 325 studies that were initially retrieved, 82 articles met the inclusion criteria. A high prevalence of vitamin D deficiency was reported, and in some regions, this was reported as >90% and was found in all age groups and in all regions of Iran. Conclusion: This review highlights the very high prevalence of vitamin D deficiency in Iran. It will be important to recognize the importance of vitamin D deficiency as a major public health problem in Iran.

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Age and Spinal Disease Correlate to Albumin and Vitamin D Status

Global Spine Journal ◽

10.1177/2192568220982561 ◽

2021 ◽

pp. 219256822098256

Author(s):

Anderson Gomes Marin ◽

Raphael de Rezende Pratali ◽

Samuel Machado Marin ◽

Carlos Fernando Pereira da Silva Herrero

Keyword(s):

Vitamin D ◽

Nutritional Status ◽

Age Groups ◽

Hypovitaminosis D ◽

Cross Sectional Study ◽

Surgical Approaches ◽

Albumin Concentration ◽

Vitamin D Status ◽

Cross Sectional ◽

Epidemiological Profile

Study Design: Cross-sectional study. Objectives: Thus, this study aimed to assess the epidemiological profile of a patient sample that underwent spinal surgery regarding their nutritional and vitamin D status. Methods: Serum albumin and vitamin D (25-hydroxyvitamin D) levels were measured in patients with different spinal surgical approaches and various pathologies at a single institution. 112 patients were retrospectively identified for inclusion and stratified by age into 4 age groups and by pathology. The nutritional status of the patients was classified in vitamin D inadequacy (< 30ng/mL), vitamin D deficiency (<20ng/mL), and hypoalbuminemia (<3.5g/dL). Data was analyzed comparing vitamin D, and albumin means considering gender, age group, and pathologies. Results: Twenty-eight (25.2%) patients had hypoalbuminemia. There was no difference between gender (p = 0.988); there was a significant decrease in albumin concentration increasing the age (p < 0.001). The prevalence of hypoalbuminemia was significantly higher in patients with trauma, tumor and infection than in those patients with degenerative and deformity diseases (p = 0.003). The prevalence of vitamin D inadequacy was 33.7%, and that of deficiency was 62.2%, while severe deficiency (< 10 ng/mL) in 16.3%. The vitamin D concentration was significantly different among the pathologies (P = 0.047), the lower concentration occurring in patients with tumor. Conclusion: Older patients, as well as patients with tumor and infectious pathologies, seem to have a higher prevalence of hypoalbuminemia, inferring malnutrition. There was a low epidemic level of vitamin D concentration, almost all patients presenting some degree of hypovitaminosis D, independent of age, gender and nutritional status.

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High Prevalence of Hypovitaminosis D in a Young Adult South Florida Population: The Effect of Vitamin D Supplementation.

10.1210/endo-meetings.2010.part1.p4.p1-158 ◽

2010 ◽

pp. P1-158-P1-158

Author(s):

AC Apaza ◽

AM Sosa Melo ◽

H Florez ◽

V Obeso ◽

L Guzman ◽

...

Keyword(s):

Vitamin D ◽

Young Adult ◽

Hypovitaminosis D ◽

Vitamin D Supplementation ◽

South Florida ◽

High Prevalence ◽

Florida Population

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Investigating the Role of Functional Polymorphism of Maternal and Neonatal Vitamin D Binding Protein in the Context of 25-Hydroxyvitamin D Cutoffs as Determinants of Maternal-Neonatal Vitamin D Status Profiles in a Sunny Mediterranean Region

Nutrients ◽

10.3390/nu13093082 ◽

2021 ◽

Vol 13 (9) ◽

pp. 3082

Author(s):

Spyridon N. Karras ◽

Erdinç Dursun ◽

Merve Alaylıoğlu ◽

Duygu Gezen-Ak ◽

Cedric Annweiler ◽

...

Keyword(s):

Vitamin D ◽

Mediterranean Region ◽

Binding Protein ◽

Hypovitaminosis D ◽

Vitamin D Status ◽

Vitamin D Binding Protein ◽

Hydroxyvitamin D ◽

High Prevalence ◽

25 Hydroxyvitamin D ◽

Causative Effect

Recent results indicate that dysregulation of vitamin D-binding protein (VDBP) could be involved in the development of hypovitaminosis D, and it comprises a risk factor for adverse fetal, maternal and neonatal outcomes. Until recently, there was a paucity of results regarding the effect of maternal and neonatal VDBP polymorphisms on vitamin D status during pregnancy in the Mediterranean region, with a high prevalence of hypovitaminosis D. We aimed to evaluate the combined effect of maternal and neonatal VDBP polymorphisms and different maternal and neonatal 25-hydroxyvitamin D (25(OH)D) cut-offs on maternal and neonatal vitamin D profile. Blood samples were obtained from a cohort of 66 mother–child pairs at birth. Our results revealed that: (i) Maternal VDBP polymorphisms do not affect neonatal vitamin D status at birth, in any given internationally adopted maternal or neonatal cut-off for 25(OH)D concentrations; (ii) neonatal VDBP polymorphisms are not implicated in the regulation of neonatal vitamin D status at birth; (iii) comparing the distributions of maternal VDBP polymorphisms and maternal 25(OH)D concentrations, with cut-offs at birth, revealed that mothers with a CC genotype for rs2298850 and a CC genotype for rs4588 tended to demonstrate higher 25(OH)D (≥75 nmol/L) during delivery (p = 0.05 and p = 0.04, respectively), after adjustments for biofactors that affect vitamin D equilibrium, including UVB, BMI and weeks of gestation. In conclusion, this study from Southern Europe indicates that maternal and neonatal VDBP polymorphisms do not affect neonatal vitamin D status at birth, whereas mothers with CC genotype for rs2298850 and CC genotype for rs4588 demonstrate higher 25(OH)D concentrations. Future larger studies are required to establish a causative effect of these specific polymorphisms in the attainment of an adequate (≥75 nmol/L) maternal vitamin D status during pregnancy.

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Vitamin D i pokazateli kal'tsiy-fosfornogo obmenau detey, prozhivayushchikh v sredney polose Rossii, v periodmaksimal'noy insolyatsii

Osteoporosis and Bone Diseases ◽

10.14341/osteo201022-6 ◽

2010 ◽

Vol 13 (2) ◽

pp. 2-6 ◽

Cited By ~ 4

Author(s):

A. V. Vitebskaya ◽

G. E. Smirnova ◽

A. V. Il'in

Keyword(s):

Vitamin D ◽

Vitamin D Deficiency ◽

Central Area ◽

Hypovitaminosis D ◽

Vitamin D Insufficiency ◽

Winter Period ◽

Published Data ◽

Healthy Children ◽

Hydroxyvitamin D ◽

Oncological Diseases

Vitamin D deficiency is associated with rickets in children and osteomalation in adults. Published data support the role of vitamin D insufficiency in development of autoimmune, cardiovascular and oncological diseases. The most precise method to diagnose vitamin D insufficiency is measuring of 25-hydroxyvitamin D (25(OH)-D). We studded the levels of vitamin D and calcium-phosphate turnover parameters during the period of maximal insolation in 140 healthy children and adolescents permanently living in the central area of Russia. Vitamin D insufficiency (25(OH)-D < 20 ng/ml) was detected in 38,6%; in 2,9% of them severe vitamin D deficiency was diagnosed (25(OH)-D < 8 ng/ml). The results correlate with data on hypovitaminosis D prevalence in countries with the same geographical latitude. To clarify the real size of required prophylaxis we need investigation of the same parameters in winter period while minimal insolation.

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Differences in vitamin D status and calcium metabolism in Saudi Arabian boys and girls aged 6 to 18 years: effects of age, gender, extent of veiling and physical activity with concomitant implications for bone health

Public Health Nutrition ◽

10.1017/s1368980011003612 ◽

2012 ◽

Vol 15 (10) ◽

pp. 1845-1853 ◽

Cited By ~ 16

Author(s):

Maryam A Al-Ghamdi ◽

Susan A Lanham-New ◽

Jalal A Kahn

Keyword(s):

Physical Activity ◽

Vitamin D ◽

Saudi Arabia ◽

Parathyroid Hormone ◽

Bone Health ◽

Age Groups ◽

Hypovitaminosis D ◽

Vitamin D Status ◽

Kingdom Of Saudi Arabia ◽

Cross Sectional

AbstractObjectiveFew data exist looking at vitamin D status and bone health in school-aged boys and girls from Saudi Arabia. The present study aimed to determine the extent of poor vitamin D status in school boys and girls aged 6–18 years and to examine if there was any difference in status with age, physical activity and veiling and concomitant effects on bone.DesignCross-sectional study.SettingJeddah, Kingdom of Saudi Arabia.SubjectsA total of 150 boys (7–16 years) and 150 girls (6–18 years) from local schools were divided into age categories: 6–9 years (elementary school); 10–12 years (secondary school); 13–14 years (middle years); 15–18 years (high school).ResultsVitamin D status was significantly lower in girls than boys in all age groups (P < 0·01), with the 15–18-year-old girls having the lowest level (22·0 (sd 9·4) nmol/l) in comparison to the 15–18-year-old boys (39·3 (sd 14·0) nmol/l) and the 6–9-year-old girls (41·2 (sd 9·3) nmol/l). Parathyroid hormone status was highest in the 15–18-year-old girls in comparison to boys of the same age. A total of 64 % of 15–18-year-old girls had 25-hydroxyvitamin D (25OHD) status <25 nmol/l in comparison to 31 % in the 13–14 years age category, 26 % in the 10–12 years category and 2·5 % in the 6–9 years category. No boys had 25OHD status <25 nmol/l. Fully veiled girls had lower 25OHD status than partly veiled or unveiled girls (P < 0·05). Low 25OHD and high parathyroid hormone was associated with lower bone mass in the 6–9 years and 13–14 years age groups (P < 0·05).ConclusionsThese data suggest significant hypovitaminosis D in older adolescent females, which is a cause for concern given that there is currently no public health policy for vitamin D in the Kingdom of Saudi Arabia.

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Sport and exercise in times of self-quarantine: How Germans changed their behaviour at the beginning of the Covid-19 pandemic

International Review for the Sociology of Sport ◽

10.1177/1012690220934335 ◽

2020 ◽

pp. 101269022093433 ◽

Cited By ~ 7

Author(s):

Michael Mutz ◽

Markus Gerke

Keyword(s):

Social Interactions ◽

Adult Population ◽

Age Groups ◽

Population Level ◽

Sports Clubs ◽

Federal States ◽

Home Based ◽

Younger Age ◽

Community Sports ◽

Sport And Exercise

Due to the massive spread of a new Coronavirus (SARS-CoV-2), many European governments enacted rules and legislations in order to reduce social interactions and contain the spread of the virus. German authorities put in force a lockdown of all non-essential infrastructure, starting on 22 March 2020. These policies included the closing of sports clubs, fitness centres and community sports grounds. Most federal states prohibited social gatherings of more than two people, thereby further restricting opportunities to play sport and exercise together. The paper addresses how Germans adapted their leisure time sport and exercise (LTSE) activities in this unprecedented situation. Based on survey data representing the adult population (⩾ 14 years, N=1001, data collection 27 March to 6 April 2020), the paper shows a significant decline in LTSE activities at population level. Overall, 31% of Germans reduced their LTSE, while 27% maintained and 6% intensified their LTSE level. A share of 36% was not engaged in LTSE, either before or at the beginning of the lockdown. Younger age groups were more likely to maintain LTSE levels compared with older ones. Comparisons of ‘reducers’ and ‘maintainers/ intensifiers’ indicate that the latter group increased home-based workouts and outdoor endurance sports, while ‘reducers’ did not find adequate substitutes for their sporting routines.

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High Prevalence of Hypovitaminosis D in Institutionalized Elderly Individuals is Associated with Summer in a Region with High Ultraviolet Radiation Levels

Nutrients ◽

10.3390/nu11071516 ◽

2019 ◽

Vol 11 (7) ◽

pp. 1516

Author(s):

Sara Estéfani S. Sousa ◽

Márcia Cristina Sales ◽

José Rodolfo T. Araújo ◽

Karine C.M. Sena-Evangelista ◽

Kenio C. Lima ◽

...

Keyword(s):

Vitamin D ◽

Dietary Intake ◽

Skin Color ◽

Hypovitaminosis D ◽

Vitamin D Supplementation ◽

Vitamin D Status ◽

Institutionalized Elderly ◽

Elderly Individuals ◽

Independent Variables ◽

High Prevalence

Vitamin D may play a significant role in regulating the rate of aging. The objective of the study was to assess vitamin D status and its associated factors in institutionalized elderly individuals. A total of 153 elderly individuals living in Nursing Homes (NH) were recruited into the study. Serum 25-hydroxyvitamin D [25(OH)D] concentration was used as the biomarker of vitamin D status, and it was considered as the dependent variable in the model. The independent variables were the type of NH, age-adjusted time of institutionalization, age, sex, skin color, body mass index, waist and calf circumference, physical activity practice, mobility, dietary intake of vitamin D and calcium, vitamin D supplementation, use of antiepileptics, and season of the year. Serum 25(OH)D concentrations less than or equal to 29 ng/mL were classified as insufficient vitamin D status. The prevalences of inadequate dietary intake of vitamin D and calcium were 95.4% and 79.7%, respectively. The prevalence of hypovitaminosis D was 71.2%, and the mean serum concentration of 25(OH)D was 23.9 ng/mL (95% confidence interval [CI]: 22.8–26.1). Serum 25(OH)D concentration was associated with the season of summer (p = 0.046). There were no associations with other independent variables (all p > 0.05). The present results showed that a high prevalence of hypovitaminosis D was significantly associated with summer in institutionalized elderly individuals.

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