scholarly journals Commentary: Trained immunity and beyond: the not-yet lost chance to win with COVID-19

2020 ◽  
Vol 4 (3) ◽  
pp. 8-10
Author(s):  
Malgorzata Kloc ◽  
Rafik Mark Ghobrial ◽  
Jacek Kubiak

COVID-19 pandemic has frightened people and governments all around the world. The common opinion is that there are no efficient preventive measures but masks, isolation, and social distancing. The deliverance is hoped from the SARS-CoV-2-specific vaccine, which must be efficient and cheap. But, so far nobody knows when, and if such a vaccine will be developed and mass-produced. Trained immunity with oral polio vaccine (OPV) was recently proposed as a temporal solution against the heavy course of COVID-19. However, politics do not seem to follow, and the scientific world should react because humanity has no time to lose. Below, we support this with our thoughts.

Author(s):  
Melanie Malave Sanchez ◽  
Paul Saleeb ◽  
Shyam Kottilil ◽  
Poonam Mathur

Abstract The global COVID-19 pandemic has raised significant concerns of developing rapid, broad strategies to protect the vulnerable population and prevent morbidity and mortality. However, even with an aggressive approach, controlling the pandemic has been challenging, with concerns of emerging variants that likely escape vaccines, non-adherence of social distancing/preventive measures by the public, and challenges in rapid implementation of a global vaccination program that involves mass production, distribution, and execution. In this review, we revisit the utilization of attenuated vaccinations, such as the oral polio vaccine, which are safe, easy to administer and likely provide cross-protection against respiratory pathogens. We discuss the rationale, data supporting its use, and detail description of available vaccines that could be repurposed for curtailing the pandemic.


2020 ◽  
Vol 32 (2 (Supp)) ◽  
pp. 255-260
Author(s):  
Bobby Joseph ◽  
Mia George Kallumkal

COVID-19 is a disease caused by the novel coronavirus (SARS-CoV-2). On January 30th, 2020 the outbreak of Novel Coronavirus 2019 was declared a Public Health Emergency of International Concern by the World Health Organization. COVID-19 was declared a pandemic on the 11th of March 2020. The virus spreads from person to person through close contact, touching contaminated surfaces and then touching the eyes, nose or mouth. Preventive measures are taken at all workplaces to stop the spread of COVID-19. Social distancing, regular hand washing with soap and water for 20 seconds, use of alcohol- based hand sanitizer and cough etiquette must be practiced at all times. Hospitals, schools, colleges, hospitality, apparel and manufacturing industries now practice hand hygiene, social distancing, regular disinfection of contaminated surfaces, staggered work shifts, correct use of face mask if mild symptoms develop and shutting down of establishments as per instructions of the local health authorities. COVID-19 is already affecting tens of millions of informal workers all around the world. India has a share of almost 90 percent of working people which amount to 400 million workers in the informal economy, who are at the risk of falling into poverty during this crisis. The current lock down measures in India have affected these workers, compelling them to return to rural areas. Poverty along with the spread of the COVID-19 would further worsen the situation. Without dwelling on the healthcare setting, this paper discusses various preventive measures to be implemented in three different sectors. These interventions can be adapted to others as well, to stop the transmission of COVID-19.


Author(s):  
Smeeta B. Kanmuse ◽  
Umapati Baragi

Diabetes mellitus is the common and major disease in India. In India more than 60 million people are diagnosed with diabetes mellitus, in 2000 India topped (31.7 million). The world followed by China prevalence is predicted to double globally from 171 million in 2000 to 360 million in 2030. Causative factor includes genetic factor, obesity, due to rising living standard and lifestyle. Important causative factor is lifestyle, by this in everyhouse one or the other is getting diabetes at the early age. So to prevent the DM the one and only way is Yoga and Ayurvedic lifestyle (Ritucharya and Dinacharya) and it is the feasible solution to arrest the rising disease. The aim of this fundamental description study is to discuss the role of Yoga and Ayurveda with special reference to causative factor and possible preventive measures in DM.


1970 ◽  
pp. 263-277
Author(s):  
Stanisława Nazaruk ◽  
Anna Klim-Klimaszewska

Experiments carried out by children are highly instructive adventures that develop interest in science. Nothing motivates a child to learn physics or chemistry more than experimentation. Supervised by their teachers, using safe reagents, chemical glass, and other equipment required to conduct experiments, “Little Scientists” discover the laws of physics and chemistry. Experimenting favors a search for answers to the most basic questions; it helps children see the magic of science and discover the secrets of the world around them. Contrary to the common opinion, holding that physical or chemical experiments may be introduced at the beginning of primary school at the earliest, preschool-age children are already prepared for such activities. The article presents a chemical experiment concerning sugar detection conducted by 6-year-olds. Research was performed to determine whether making chemical experiments has an impact on the level of children’s knowledge about sugars. The study included 20 children who carried out chemical experiments in four parallel groups. The level of knowledge was tested twice: first prior to the experiment and then following the experiment. The analysis of the data obtained demonstrated that after the experiment the level of children’s knowledge about sugars increased significantly, as evidenced by the t-Student Test outcomes.


Recently, the outbreak of Coronavirus Disease (COVID-19) has spread rapidly across the world and thus social distancing has becomeone of mandatory preventive measures to avoid physical contact. COVID-19 is a disease caused by a severe respiratory syndrome coronavirus. The continuous development of technology of IT enabled computers to see and learn. There are many viable applications for computer learning and vision to solve new tasks. In this paper, we propose a framework, able of automatically detect no. of human bodies present in a single image, acquired by a traditional low-cost camera. In this paper Viola jones algorithm is usedto detect human monitoring social distancing norm. System is divided into two parts, the first part is about person detection whereas second part is about monitoring whether people are following social distancing or not, it is applicable if image containsmore than one human. This paper is going to study and understand the Viola-Jones algorithm by implementing the whole detection framework and based on the implementation, conduct experiment to hopefully further improve the performance.


PEDIATRICS ◽  
2016 ◽  
Vol 137 (Supplement 3) ◽  
pp. 389A-389A
Author(s):  
Oluyemisi O. Falope ◽  
Korede K. Adegoke ◽  
Chukwudi O. Ejiofor ◽  
Nnadozie C. Emechebe ◽  
Taiwo O Talabi ◽  
...  

2019 ◽  
Vol 7 (8) ◽  
pp. 12
Author(s):  
Kunal Debnath

High culture is a collection of ideologies, beliefs, thoughts, trends, practices and works-- intellectual or creative-- that is intended for refined, cultured and educated elite people. Low culture is the culture of the common people and the mass. Popular culture is something that is always, most importantly, related to everyday average people and their experiences of the world; it is urban, changing and consumeristic in nature. Folk culture is the culture of preindustrial (premarket, precommodity) communities.


2020 ◽  
Vol 11 (SPL1) ◽  
pp. 171-174
Author(s):  
Tarare Toshida ◽  
Chaple Jagruti

The covid-19 resulted in broad range of spread throughout the world in which India has also became a prey of it and in this situation the means of media is extensively inϑluencing the mentality of the people. Media always played a role of loop between society and sources of information. In this epidemic also media is playing a vital role in shaping the reaction in ϑirst place for both good and ill by providing important facts regarding symptoms of Corona virus, preventive measures against the virus and also how to deal with any suspect of disease to overcome covid-19. On the other hand, there are endless people who spread endless rumours overs social media and are adversely affecting life of people but we always count on media because they provide us with valuable answers to our questions, facts and everything in need. Media always remains on top of the line when it comes to stop the out spread of rumours which are surely dangerous kind of information for society. So on our side we should react fairly and maturely to handle the situation to keep it in the favour of humanity and help government not only to ϑight this pandemic but also the info emic.


Author(s):  
Ghotekar D S ◽  
Vishal N Kushare ◽  
Sagar V Ghotekar

Coronaviruses are a family of viruses that cause illness such as respiratory diseases or gastrointestinal diseases. Respiratory diseases can range from the common cold to more severe diseases. A novel coronavirus outbreak was first documented in Wuhan, Hubei Province, China in December 2019. The World Health Organization (WHO) has declared the coronavirus disease 2019 (COVID-19) a pandemic. A global coordinated effort is needed to stop the further spread of the virus. A novel coronavirus (nCoV) is a new strain that has not been identified in humans previously. Once scientists determine exactly what coronavirus it is, they give it a name (as in the case of COVID-19, the virus causing it is SARS-CoV-2).


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