scholarly journals DYSLIPIDEMIA;

2018 ◽  
Vol 21 (05) ◽  
pp. 956-959
Author(s):  
Imran Karim ◽  
Ahmed Khan Zardari ◽  
Muhammed Khalid Shaikh ◽  
Zulfiqar Ali Qutrio Baloch ◽  
Syed Zulfiquar Ali Shah

Objective: To determine the frequency of dyslipidemia in Helicobacter pyloriinfected patients. Patients and methods: This cross sectional descriptive study of six monthsstudy was conducted at Liaquat University Hospital Hyderabad from 01-03-2012 to 31-08-2012. All the patients between 19 to 60 years of age present with symptoms of dyspepsia,bloating or epigastric discomfort for more than 01 week duration were admitted and evaluatedfor Helicobacter pylori infection. Thereafter the positive cases (Helicobacter pylori infectedpatients) were further evaluated for dyslipidemia. Results: During six month study period,total 144 patients (95 males and 49 females) with Helicobacter pylori infection were evaluatedfor dyslipidemia (lipid profile). Majority of patients were from urban areas 110/144 (76%).The mean ±SD for age of patients with Helicobacter pylori infection was 35.94±10.77. Themean age ±SD of dyslipidemic patient was 32.62±6.52. The dyslipidemia was identified in 87(60.4%) patients, of which 51(58.6%) were males and 36(41.4%) were females. Regarding thepattern of dyslipidemia, ten (11.4%) patients had raised serum triglycerides level, twenty eight(32%) had raised LDL-C level, twenty six (28.9%) had raised serum cholesterol level, seven(8.7%) had low HDL-C level and sixteen (18.3%) had mixed dyslipidemia. The mean ±SD ofhypertriglyceridemia, ↑HDL-C, ↑LDL-C and hypercholesterolemia in dyslipidemic Helicobacterpylori infected was 280.72±22.85, 24.21±2.63, 180.63±12.98 and 285.21±23.63 respectively.Conclusions: The H. pylori infected patients are prone to acquire dyslipidemia, therefore thepresent study observed 60.4% prevalence of dyslipidemia with male predominance (58.6%)

2018 ◽  
Vol 25 (05) ◽  
pp. 753-758
Author(s):  
Arshad Sattar Lakho ◽  
Aqeel Ahmed Channa ◽  
Abdul Ghaffar Dars ◽  
Syed Zulfiquar Ali Shah ◽  
Muhammad Iqbal

Objectives: To determine the frequency of vitamin B12 deficiency in patientswith hypothyroidism. Study Design: Cross sectional descriptive study. Period: 12-05-2016to 11-11-2016. Setting: Liaquat University Hospital Jamshoro / Hyderabad. Patients andMethods: All the patients of known hypothyroid patients for ≥01month duration, 20-50 yearsof age, either gender were explored for serum vitamin B12 level. The SPSS was used tomanipulate the data in relation to mean ±SD, frequencies and percentages and through chisquaretest to get the p-values and its level of significance (≤0.05). Results: Total 145 patientswith hypothyroidism were evaluated for B12 deficiency, of which 97 (66.8%) were males and48 (33.1%) were females respectively. Ninety patients (62%) were from urban areas while 55(37.9%) was rural population. The mean ±SD for age of overall population was 41.83±8.93years while the mean age ±SD for vitamin B12 deficient and non deficient was 39.96±7.82and 40.74±8.54 years respectively. The vitamin B12 deficiency was observed in one hundredand five patients (72%), of which 69 (65.7%) males and 36 (34.3%) females. The mean ± SDfor duration of infection in overall population was 5.32±1.53 months while it was 5.81±1.43 invitamin B12 deficient individuals. Conclusion: The vitamin B12 deficiency is more pronouncedin hypothyroid patients. In present series vitamin B12 deficiency was observed in 105 (72%)individuals with male predominance 69 (65.7%).


2019 ◽  
Vol 26 (08) ◽  
pp. 1261-1265
Author(s):  
Tooba ◽  
Riaz Hussain Awan ◽  
Seema Nayab ◽  
Khadim Hussain Awan ◽  
Faqir Muhammad Awan

To evaluate the frequency of Helicobacter pylori in individuals with functional dyspepsia. Study Design: Cross sectional descriptive study. Period: Six months from 01-May-2014 to 31-10-2014. Setting: Liaquat National Hospital, Karachi. Materials and Methods: All the patients between 18 to 70 years of age diagnosed as functional dyspepsia for more than 03 months duration were admitted and evaluated for Helicobacter pylori infection through histopathological examination. Results: Total 121 subjects with functional dyspepsia were screened for Helicobacter pylori infection. The mean ±SD for age of subjects with functional dyspepsia was 41.74±08.87. The mean age ±SD of Helicobacter pylori infected individuals was 40.70±7.82 while the mean ±SD of age in helicobacter pylori negative patients was 40.55±10.63. Majority of the subjects were out-patients, 30-39 years of age with male predominance. The most common duration of disease observed was 6-9 months with epigastric pain and burning the predominant symptoms. The Helicobacter pylori infection was observed in 78(64.4%) individuals, of which 55 were males and 23 were males (p=<0.01). Conclusion: The functional dyspeptic patients are prone to acquire Helicobacter pylori infection therefore present study reported 64.4% prevalence for H. pylori infection with male gender predominance.


Author(s):  
Okonkwo Lilian Okwubenata ◽  
Musa Bolanle Olufunke Priscilla ◽  
Hali Bello ◽  
Mustapha Shettima Kagu

Background Helicobacter pylori infection is prevalent in African region especially in areas with low socioeconomic status. This study aimed to determine the prevalence and risk factors for Helicobacter pylori Infection among individuals with and those without dyspepsia Materials and Methods The study was cross sectional in which individuals with and those without dyspepsia were enrolled. The prevalence for Helicobacter pylori infection was determined by the screening of Helicobacter pylori immunoglobulin G and this was compared across variables of interest. IBM SPSS was used for the data analysis. Results Overall prevalence of Helicobacter pylori immunoglobulin G was 44 (37.9 %). There was no association between H pylori infection and dyspepsia (0.894). There was statistically significant association between residing in rural areas and acquiring of Helicobacter pylori infection (P= 0.011). Study participants from rural areas had significantly higher and lower pit latrines and water closet toilets respectively than the study participants who reside in urban areas (P= 0.0001). Conclusion Modest prevalence of Helicobacter pylori infection was observed and no association between H pylori infection and dyspepsia was observed. There is a need to take strategic measures towards improving level of socio-economic status of the rural areas so as to reduce the risk of contracting Helicobacter pylori infection in people living in rural areas


2015 ◽  
Vol 22 (01) ◽  
pp. 076-080
Author(s):  
Shuaib Ansari ◽  
Irfan Murtaza Shahwani ◽  
Zeeshan Ali ◽  
Syed Zulfiquar Ali Shah ◽  
Faisal Shahab

Objective: To determine the frequency of raised C-reactive protein (CRP) inpatients with metabolic syndrome. Patients and methods: This cross sectional descriptivestudy of six months study was conducted at Liaquat University Hospital Hyderabad. All thepatients of 20 to 60 years of age, of either gender presented with symptoms of metabolicsyndrome for more than 01 year duration were admitted and evaluated for C-reactive protein.The data was analyzed in SPSS 16 and the frequency and percentage was calculated. Results:Total one hundred patients (59 females and 41 males) with metabolic syndrome were evaluatedfor C-reactive protein. The mean waist circumference for males and female patients with raisedCRP was 48.93±2.33 and 48.42±3.41 while the mean ±SD of serum triglycerides level for maleand female with raised CRP was 192.41±3.21 and 196.31±3.43 respectively. The mean ±SD ofserum HDL-C level for male and female with raised CRP was 28.32±1.22 and 25.31±1.42. Themean ±SD of systolic and diastolic pressure for males and female patients with raised CRP was150±3.42 and 100.51±4.42. The mean ±SD of serum fasting blood sugar for male and femalepatients with raised CRP was 131.52±3.33 and 143.42±7.42 respectively. The mean ±SD ofCRP for male and female patients with raised CRP was 4.42±1.21 and 5.8±2.52. In relationto gender distribution, the majority of subjects from 40-49 years of age group with femalepredominance (p = 0.01) while the CRP was raised in 67% patients in relation to age (p=0.05)and gender (p=0.04) respectively. Out of 67 subjects with raised CRP 44 were females and 23were males.Conclusions: The CRP was raised in patients with metabolic syndrome.


2021 ◽  
Vol 5 (2) ◽  
Author(s):  
Muhammad Shoaib ◽  
Mirza Muhammad Abdullah ◽  
Kanwal Sharif

Background: Childhood Recurrent Abdominal Pain results in the one of the adulthood complications i.e., irritable bowel syndrome, which is a gastro-intestinal disease. The stomach’s acidic environment is the growth site for Helicobacter Pylori, a pathogenic Gram-negative bacterium with rod shape. It is the main reason for chronic gastritis, gastric adenocarcinoma, peptic ulcers, non-ulcer dyspepsia and mucosa-associated lymphoid tissue (MALT) lymphoma. According to one estimate, 50% of people in world are infected with Helicobacter Pylori. Currently the developing countries are on the hit list of Helicobacter Pylori. The objective of this study was to determine the frequency of Helicobacter pylori infection in the children having recurrent abdominal pain. Materials and Methods: It was a cross-sectional study. This research was carried out during 1.1.2018 to 1.6.2018 in the D.H.Q hospital Mirpur AJK. The sample was consisted of 200 participants among them the proportion of Helicobacter was 8% in patients with Recurrent Abdominal Pain. Results: The mean age of the patients was 12.43 ± 1.23 years. Mostly the age of the sample group was between 8 to16 years. The 4.23 ± 0.47 months was the mean time period of abdominal pain. Helicobacter pylori was found in 47% of patients. Conclusion: In paediatric population, Helicobacter pylori is very common with Recurrent Abdominal Pain. It is a severe problem in children and further study is recommended to explore the risk element associated with this increase trouble of Helicobacter Pylori.


Author(s):  
Hafiza Khatoon ◽  
Rukhsana Ahmed ◽  
Ambreen Naz ◽  
Nousheen Mushtaq ◽  
Asma Irfan ◽  
...  

Objective: To determine the frequency of thrombocytopenia in pre-eclamptic women presented at Isra University Hospital Hyderabad. Patients and Methods: This cross sectional descriptive study of six months study was conducted at Isra university hospital from April 2019 to September 2019. All the patients between ≥18 - 45 years of age diagnosed preeclampsia were admitted and evaluated for thrombocytopenia. Results: During six month study period, total of 177 patients with preeclampsia were evaluated for thrombocytopenia. The majority of patients were from urban areas 125/177 (70.6%). The mean ±SD for maternal and gestational age of the preeclamptic patient was 32.75±8.85 and 28.75±7.63 whereas the mean platelet count was 93200±10.74 respectively. The majority of the patients were 21-30 years of age (54.8%) and the finding was statistically significant with gestational age [p=0.002]. The thrombocytopenia was observed in 99/177 (55.9%) and is statistically with relation to maternal age, gestational age and parity while in context to gravida and duration of disease it is non significant. Conclusion: A significantly high frequency of thrombocytopenia (55.9%) was recorded in the patients with preeclampsia and is statistically with relation to maternal and gestational age and parity.


2018 ◽  
Vol 21 (05) ◽  
pp. 960-964
Author(s):  
Muhammed Khalid Shaikh ◽  
Saeem Akhtar ◽  
Ahmed Khan Zardari ◽  
Suneel Arwani ◽  
Syed Zulfiquar Ali Shah

…Objective: To determine the serum iron level in Helicobacter pylori infectedpatients. Patients and methods: This cross sectional descriptive study was conducted atLiaquat University Hospital (a tertiary care teaching hospital) Hyderabad from July 2013 toDecember 2013. All the patients with history of presented with acute abdominal pain, dyspepsia,bloating and epigastric discomfort were evaluated for Helicobacter pylori infection by serology.Thereafter the Helicobacter pylori positive individuals were further evaluated for serum ironlevel. The data was collected, saved and analyzed in SPSS version 11.00. Result: During sixmonth study period total one hundred patients of H. pylori infection was recruited, of whichsixty three (63%) were males and thirty seven were females. Sixty six (66%) patients belongedto urban areas while thirty four (34%) were rural population. The mean age ±SD for overallpopulation was 37.35±14.0 where as the mean age ±SD of male and female population was38.88±6.77 and 35.67±8.87 respectively. The serum iron was low in 68% Helicobacter pyloriinfected patients, of which 48 were males and 20 were females (p=0.02). The overall mean±SD for serum iron level in study population was 49.17±37.86 mmol/L whereas the mean ±SDof serum iron for male and female Helicobacter pylori infected population was 42.69±34.15and 60.18± 41.66 (p=0.03). Conclusions: An association was identified between Helicobacterpylori and iron deficiency


2021 ◽  
Vol 80 (Suppl 1) ◽  
pp. 923.4-924
Author(s):  
H. Hachfi ◽  
D. Khalifa ◽  
M. Brahem ◽  
N. Ben Chekaya ◽  
M. Younes

Background:Knee osteoarthritis and obesity are both major health problems. It is now admitted that the prevalence of knee osteoarthritis gets higher with obesity and that weight loss helps knee function and allows patients to avoid surgery.Objectives:The aim of this study was to study the influence of obesity on knee osteoarthritis features.Methods:A cross-sectional study was conducted in the university hospital Taher Sfar of Tunisia over a period of 6 months. Patients who had knee osteoarthritis confirmed by radiographs were included. Sociodemographic, clinical, radiological and therapeutic data were collected from medical records and visits. Obesity was defined by a body mass index (BMI) ≥30. Functional impairment was assessed by the Womac index and Lequesne index.Results:The study included 186 patients. There were 31 males and 155 femmes. The mean age was 60±10 years. The percentage of obese patients was 53,8%. The mean age was similar in both groups obese and non obese. There were more women in the obese group compared to the non obese group (p=0.0001), more patients who had diabetes mellitus and dyslipidemia (p=0.002). Non-obese patients had a shorter duration of symptoms with no statistical significance (p=0.151). Obese patients had more involvement of both knees (p<0.0001). Obesity did not have an impact on pain severity. Severity of radiological images (p=0,0001) were more frequent in obese patients. Functional impairment was similar in both groups. However, the percentage of patients having a very important functional impairment with Lequesne index was higher in obese patients (p<0.029). Obese patients also needed more physical therapy sessions (p=0.035).Conclusion:Knee osteoarthritis in obese patients is characterized with the femlae gender predominance, bilateral knee involvement, and a more severe images on radiographs. Thus the need for better control of weight and the importance of physical activity.References:[1]Coggon D, Reading I, Croft P, et al. Knee osteoarthritis and obesity. Int J Obes Relat Metab Disord J Int Assoc Study Obes 2001; 25: 622–627.Disclosure of Interests:None declared


Urolithiasis ◽  
2021 ◽  
Author(s):  
R. A. Kingma ◽  
M. J. H. Voskamp ◽  
B. H. J. Doornweerd ◽  
I. J. de Jong ◽  
S. Roemeling

AbstractCone beam computed tomography (CBCT) provides multiplanar cross-sectional imaging and three-dimensional reconstructions and can be used intraoperatively in a hybrid operating room. In this study, we investigated the feasibility of using a CBCT-scanner for detecting residual stones during percutaneous nephrolithotomy (PCNL). Intraoperative CBCT-scans were made during PCNL procedures from November 2018 until March 2019 in a university hospital. At the point where the urologist would have otherwise ended the procedure, a CBCT-scan was made to image any residual fragments that could not be detected by either nephroscopy or conventional C-arm fluoroscopy. Residual fragments that were visualized on the CBCT-scan were attempted to be extracted additionally. To evaluate the effect of this additional extraction, each CBCT-scan was compared with a regular follow-up CT-scan that was made 4 weeks postoperatively. A total of 19 procedures were analyzed in this study. The mean duration of performing the CBCT-scan, including preparation and interpretation, was 8 min. Additional stone extraction, if applicable, had a mean duration of 11 min. The mean effective dose per CBCT-scan was 7.25 mSv. Additional extraction of residual fragments as imaged on the CBCT-scan occurred in nine procedures (47%). Of the follow-up CT-scans, 63% showed a stone-free status as compared to 47% of the intraoperative CBCT-scans. We conclude that the use of CBCT for the detection of residual stones in PCNL is meaningful, safe, and feasible.


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