scholarly journals MODIFIKASI TAI CHI DAN SENAM JANTUNG SEHAT PADA PROFIL LIPIDA DAN KEBUGARAN PRA LANSIA The Tai Chi Modification (Mtc) And Gymnastics (Senam Jantung Sehat) Upon Lipid Profile And Physical Fitness At Middle Age.

2014 ◽  
Vol 1 (1) ◽  
Author(s):  
M. Zainul Arifin
Keyword(s):  
Physical Fitness ◽  
High Density Lipoprotein ◽  
Lipid Profile ◽  
Tai Chi ◽  
Middle Age ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Control Group ◽  
Low Density ◽  
Randomized Control

Penelitian ini bertujuan untuk menciptakan Modifikasi Tai Chi (MTC) berupa gerakan yang sesuai dan efektif bagi pra lansia dalam hal perbaikan profil lipida dan kebugaran tubuh  disamping Senam Jantung Sehat (SJS). Jenis penelitian ini adalah penelitian eksperimen dengan menggunakan desain Randomized Control Group Pretest Posttest. Populasi penelitian adalah laki-laki pra lansia (40 th s/d 49 th) dan sehat di Puri Mojobaru RW 03, Canggu, Mojokerto berjumlah 300 orang. Melalui rumus Lemeshow ditentukan jumlah sampel 27 orangyang dibagi tiap kelompok 9 orang secara random, ada tiga kelompok yaitu kelompok 1 diberi perlakuan Modifikasi Tai Chi berjumlah 9 orang, kelompok 2 diberi perlakuan Senam Jantung Sehat berjumlah 9 orang dan kelompok 3 adalah kontrol berjumlah 9 orang. Perlakuan pada kelompok Modifikasi Tai Chi dan Senam Jantung Sehat berdurasi 60 menit per latihan, frekuensi 3 x per minggu, selama 8 minggu. Variabel yang akan diukur adalah: 1) total colesterol (TC), 2)trigliserida (TG), 3) low density lipoprotein (LDL), 4) high density lipoprotein (HDL), 5) perbandingan HDL/TC dan kebugaran terdiri atas: 1) kapasitas aerobic maksimal (VO2max), 2) efisiensi ambilan oksigen saat ventilasi (VO2/VE). Data variabel terikat diukur sebelum perlakuan (pretest) dan sesudah perlakuan (posttest). Selanjutnya data diolah menggunakan analisis statistik meliputi : Anova, LSD (α=0,05) dengan menggunakan program komputer SPSS versi 16. Hasil penelitian menunjukkan bahwa : 1) MTC memperbaiki TC (p=0,000, TG (p=0,000), LDL (p=0,005), HDL (p=0,000), HDL/TC (p=0,000), VO2max (p=0,000), VO2/VE (p=0,019). 2) SJS memperbaiki TC (p=0,000), TG (p=0,000), LDL (p=0,005), HDL (p=0,000), HDL/TC (p=0,000), VO2max (p=0,019), VO2/VE(p=0,006). 3) Perbedaan perbaikan profil lipida dan peningkatan kebugaran antara MTC dengan SJS adalah TC(p=0,000), TG (p=0,000), LDL (p=0,000), HDL (p=0,000), HDL/TC (p=0,000), VO2max (p=0,000), VO2/VE (p=0,645) . sehingga diketahui MTC lebih efektif memperbaiki profil lipida dan kebugaran tubuh pra lansia dari pada SJS. Jadi Modifikasi Tai Chi dapat dijadikan sebagai alternatif yang lebih baik dari pada Senam Jantung Sehat dalam hal memperbaiki profil lipida dan meningkatkan kebugaran tubuh, terutama pada pra lansia, walaupun VO2/VE antara MTC dan SJS tidak ada beda.

scholarly journals Dyslipidemia in Psoriasis: A Case - Controlled Study

2021 ◽  
Vol 19 (2) ◽  
pp. 39-43
Author(s):  
Monique Kafle ◽  
Madhu Gyawlee ◽  
Amit Amatya ◽  
Bhaskar Mohan Meher Kayastha ◽  
Smarika Upadhyaya
Keyword(s):  
High Density Lipoprotein ◽  
Lipid Profile ◽  
Total Cholesterol ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
High Density ◽  
Controlled Study ◽  
Control Group ◽  
Low Density ◽  
Chronic Inflammatory Condition

INTRODUCTION:  Psoriasis is a chronic inflammatory condition of skin which can be associated with other ailments including dyslipidemia which is an abnormal serum lipid profile. OBJECTIVE: The aim of present study was to determine correlation between dyslipidemia and Psoriasis of patients visiting the Out-patient Department of Patan Hospital METHODS: Ninety patients were selected for study. Among them 30 patients with psoriasis were taken as cases and 60 patients that matched for age and sex with Psoriasis patients were taken as controls. The lipid profile that comprised four parameters: serum High-density Lipoprotein, Low-density Lipoprotein, Total Cholesterol and Triglyceride were determined and compared for both case and control groups. RESULTS: More than 95% of the psoriatic patients had dyslipidemia. The odds of dyslipidemia among Psoriatic patients were 1.709 times higher compared to control group (p <0.001). Among the parameters, results showed High-density lipoprotein was significantly lower while Triglyceride was significantly higher among the cases compared to controls with p value of 0.012 and 0.001 respectively. The risk factors like smoking and alcohol were present in higher proportions among the patients with dyslipidemia but it failed to reach statistical significance. With increase in duration of Psoriasis and PASI scores, lipid parameters i.e., Total cholesterol, triglyceride and Low-density lipoprotein increased while High density lipoprotein decreased but this correlation was insignificant. CONCLUSION: This study showed Dyslipidemia is significantly higher among patients with Psoriasis especially lipid profile parameters Triglyceride and total cholesterol. Thus, timely screening and management of dyslipidemia among Psoriatic patients might be helpful in prevention of future cardiovascular events.

scholarly journals PENGARUH VIRGIN COCONUT OIL TERHADAP KADAR KOLESTEROL HDL DARAH

2013 ◽  
Vol 4 (2) ◽  
Author(s):  
Sammy L Bolang ◽  
Djon Wongkar ◽  
Ronald I Ottay
Keyword(s):  
High Density Lipoprotein ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Coconut Oil ◽  
High Density ◽  
Control Group ◽  
Low Density ◽  
Virgin Coconut Oil ◽  
The Mean ◽  
Randomized Control

Abstract: High Density Lipoprotein Cholesterol (HDL-C) has some protective roles in minimizing cardiovascular diseases. The risks of cardiovascular diseases decrease 2-3% by increasing 1 mg/dL of HDL-C. Although the blood levels of triglyceride, total cholesterol, and low density lipoprotein (LDL) are low, these risks are still high if the HDL-C is low. The purpose of this study was to find out whether the consumption of virgin coconut oil (VCO) could increase the HDL-C level. This study used pre and post tests in a randomized control group design. Samples consisted of 39 male students at the ages of 19 ± 1.6 years. Nineteen students who were administered VCO 20 ml twice daily (pre-breakfast and pre-dinner) for two weeks belonged to the VCO group, while the others belonged to the control group. The result showed that the mean HDL-C level of the VCO group at day 15 was significantly higher (P < 0.05) than at day 1 before VCO administration, with an increase of 10.45%. The mean HDL-C increase of the VCO group at day 15 was also significantly higher (P < 0.05) than the difference of the HDL-C level at day 1 and day 15 of the control group. Conclusion: two-week administration of VCO twice daily could increase HDL-C levels.Keywords: virgin coconut oil, High Density LipoproteinAbstrak: Kolesterol high density lipoprotein (HDL-C) berperan protektif terhadap penyakit kardiovaskular. Setiap peningkatan kadar HDL-C 1 mg/dL, terjadi penurunan 2-3% risiko terkena penyakit kardiovaskular. Walaupun kadar trigliserida, kolesterol total, kolesterol low density lipoprotein (LDL-C) rendah, risiko penyakit kardiovaskular tetap tinggi bila kadar kolesterol HDL juga rendah. Penelitian ini bertujuan untuk mendapatkan apakah konsumsi virgin coconut oil (VCO) dapat meningkatkan kadar kolesterol HDL darah. Rancangan penelitian yang digunakan yaitu randomized control group pre-test and post-test. Sampel penelitian sebanyak 39 orang mahasiswa laki-laki dengan usia rata-rata 19 ± 1,6 tahun. Sembilan belas mahasiswa mengonsumsi VCO 20 mL dua kali sehari sebelum makan pagi dan malam selama dua minggu; sampel lainnya menjadi kelompok kontrol. Rerata kadar kolesterol HDL darah setelah mengonsumsi VCO (hari ke-15) lebih tinggi secara bermakna (P < 0,05) dibandingkan dengan rerata kadar HDL-C darah sebelum mengonsumsi VCO (hari ke-1), dengan peningkatan sebesar 10,45%. Rerata kenaikan kadar HDL-C darah hari ke-15 setelah mengonsumsi VCO (p < 0,05) lebih tinggi secara bermakna (P < 0,05) dibandingkan selisih antara kadar kolesterol HDL darah hari ke-1 dan ke-15 kelompok kontrol. Simpulan: konsumsi VCO selama dua minggu dapat meningkatkan kadar HDL-C.Kata kunci: virgin coconut oil, High Density Lipoprotein

Effect of Turmeric and Ginger on Lipid Profile in Male Rats Exposed to Oxidative Stress

2019 ◽  
Vol 10 (01) ◽  
Author(s):  
Eman A. Al-Rekabi ◽  
Dheyaa K. Alomer ◽  
Rana Talib Al-Muswie ◽  
Khalid G. Al-Fartosi
Keyword(s):  
Oxidative Stress ◽  
Hydrogen Peroxide ◽  
Drinking Water ◽  
Lipid Profile ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Male Rats ◽  
Control Group ◽  
Very Low Density Lipoprotein ◽  
Low Density

The present study aimed to investigate the effect of turmeric and ginger on lipid profile of male rats exposed to oxidative stress induced by hydrogen peroxide H2O2 at a concentration of 1% given with consumed drinking water to male rats. Methods: 200 mg/kg from turmeric and ginger were used, and the animals were treatment for 30 days. Results: the results showed a significant increase in cholesterol, triglycerides, low density lipoprotein (LDL), very low density lipoprotein (VLDL), whereas it explained a significant decrease in high density lipoprotein (HDL) of male rats exposed to oxidative stress when compared with control group. the results showed a significant decrease in cholesterol, triglycerides, (LDL), (VLDL), whereas it explained a significant increase in (HDL) of rats treated with turmeric and ginger at dose 200 mg/kg when compared with male rats exposed to oxidative stress.

scholarly journals Effect of Whole Quail (Coturnix japonica) Egg Consumption on some Reproductive Parameters and Lipid Profile of Male Albino Rat (Rattus norvegicus)

2017 ◽  
Vol 9 (3) ◽  
pp. 315-320 ◽  
Author(s):  
Chidozie N. OKOYE ◽  
Samuel O. EKERE ◽  
Onyinyechukwu A. AGINA ◽  
Ikechukwu J. UDEANI ◽  
Chukwunonso K. EZEASOR
Keyword(s):  
Lipid Profile ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Control Group ◽  
Low Density ◽  
Epididymal Sperm ◽  
Treatment Groups ◽  
Egg Consumption ◽  
Group A ◽  
The Mean

The present study evaluated the effect of whole egg consumption on the liver, testes, cauda epididymal sperm reserve and lipid profile of male rats. These evaluations were carried out on adult twenty (20) male albino rats, which were randomly selected into four groups of 5 rats each, designated groups A, B, C and D. Group A was the control group and received only equivalent volume of distilled water, while groups B, C and D received 0.25mg/kg, 0.5mg/kg; and 1.0mg/kg body weight of the quail egg respectively. Standard procedures were carried out in the tissue processing, cauda epididymal sperm reserve and in lipid profile determinations. On days 35 and 49, the mean serum total cholesterol value of group D was significantly lower than that of the control group. On day 35, the mean serum low density lipoprotein and high density lipoprotein (LDL and HDL cholesterol) values of all the treatment groups were significantly lower and higher than that of the control group, respectively. However, on days 49 and 63, the mean serum very low density lipoprotein (VLDL cholesterol) and triglyceride values of all the treatment groups were significantly higher than that of the control group. A significant increase in cadual epididymal sperm count (CESR) was recorded on day 63 at the mid and high doses. No obvious pathological lesions were observed in the histomorphology of the testes and liver when compared to the control. Therefore, whole quail egg consumption caused an increase in serum triglyceride and very low density lipoprotein concentration, and also improved fertility. In other words, prolonged consumption of quail egg should be done with caution as it may predispose one to cardiovascular disease.

scholarly journals Effect of Some Strains of Lactic Acid Bacteria and Their Mixture on the Level of Fats and Cholesterol in Albino Rats (Rattus norvegicus) Male with Hypothyroidism Induced Using Carbimazole

2021 ◽  
Vol 34 (1) ◽  
pp. 139-146
Author(s):  
Elham K. Nasser ◽  
Kithar R. Majeed ◽  
Hayder I. Ali
Keyword(s):  
High Density Lipoprotein ◽  
Low Density Lipoprotein ◽  
Control Sample ◽  
Density Lipoprotein ◽  
High Density ◽  
Control Group ◽  
Albino Rats ◽  
Very Low Density Lipoprotein ◽  
Low Density ◽  
Fortified Milk

Fortified milk containing Lactobacillus plantarum, L. casei, and L. acidophilus isolates and their mixture were used in dosing the male albino rats at an age of 9-12 weeks at an average of 23 g with induced hypothyroidism at a concentration of 0.6 g.kg-1 of carbimazole. Total cholesterol, triglycerides, high-density lipoprotein (HDL), low-density lipoprotein (LDL), and very-low-density lipoprotein (VLDL) were estimated. The results showed a significant increase in the level of triglycerides (TG), cholesterol and triglycerides. Low-density lipoprotein (LDL) and very-low-density lipoprotein (VLDL), with a significant decrease in the level of high-density lipoprotein (HDL) in infected male mice, compared to the control sample, and upon dosing with liquid milk fortified, it returned to its normal level without significant differences from the control group.

scholarly journals Efficiency of Barley Bran and Oat Bran in Ameliorating Blood Lipid Profile and the Adverse Histological Changes in Hypercholesterolemic Male Rats

2013 ◽  
Vol 2013 ◽  
pp. 1-10 ◽  
Author(s):  
Haddad A. El Rabey ◽  
Madeha N. Al-Seeni ◽  
Hanan M. Amer
Keyword(s):  
High Density Lipoprotein ◽  
Lipid Profile ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Negative Control ◽  
High Density ◽  
Low Density ◽  
Oat Bran ◽  
Barley Bran ◽  
Kidney Liver

The efficiency of oat bran and barley bran in lowering the induced hyperlipidemia and hypercholesterolemia in blood of male Albino rats (Rattus rattus) was studied. Twenty rats were divided into four groups each consisted of five rats and fed the specified test diets for eight weeks. The first group (G1) is the negative group which was fed basal diet, the second group (G2) was fed 1.0% cholesterol, was the third group (G3) fed 1.0% cholesterol and 10% oats bran, and the fourth group (G4) was fed 1.0% cholesterol and 10% barley bran. Feeding rats on 1% cholesterol significantly increased serum total cholesterol, low density lipoprotein, and very low density lipoprotein and triglyceride and decreased serum high density lipoprotein. Furthermore, enzyme activity of alanine aminotransferase, aspartate aminotransferase, and alkaline phosphatase was increased, and lipid peroxide was increased, whereas catalase and glutathione-S-transferase were decreased. Kidney functions parameters in the cholesterol supplemented group were elevated compared with the negative control. In addition, histological alteration in kidney, liver, heart, and testes was observed, compared with the negative control. Hypercholesterolemic rats supplemented with oat bran and barley bran showed significant decrease in lipid parameters, significant increase in high density lipoprotein-cholesterol, improved antioxidant enzyme, and improved histopathology of kidney, liver, heart, and testes. In conclusion, both oat bran and barley bran had protective effects against induced hyperlipidemia and improved histological alterations. Oat bran appeared more efficient than barley bran in lowering the lipid profile levels in hypercholesterolemic rats.

scholarly journals Evaluation of Lipid Profile in Patients with Cherry Angioma: A Case-Control Study in Guilan, Iran

2018 ◽  
Vol 2018 ◽  
pp. 1-5 ◽  
Author(s):  
Abbas Darjani ◽  
Rana Rafiei ◽  
Sareh Shafaei ◽  
Elahe Rafiei ◽  
Hojat Eftekhari ◽  
...  
Keyword(s):  
High Density Lipoprotein ◽  
Lipid Profile ◽  
Serum Lipids ◽  
Case Control Study ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Case Control ◽  
Angiogenic Factors ◽  
Low Density ◽  
Control Study

Background. Cherry angioma is the most common type of acquired cutaneous vascular proliferation which would increase with aging due to some angiogenic factors but the exact pathogenesis is unknown. Usually angiogenic factors are synthesized in human body to compensate occlusive effects of atherogenic agents such as serum lipids. Our hypothesis was that increased levels of these angiogenic factors could be a trigger for development of cherry angioma. This study has been designed to compare frequency of dyslipidemia in subjects with and without cutaneous cherry angioma. Methods. In this case-control study, 122 cases with cherry angioma and 122 control subjects without cherry angioma were enrolled. Demographic characteristics, number of the cherry angioma lesions, and serum lipid profile were collected for all subjects. The data was analyzed using SPSS 18 software. Results. Mean levels of the total cholesterol, triglyceride, low-density lipoprotein, and high-density lipoprotein were higher in patients with cherry angioma compared to control subjects in which differences were significant for total cholesterol, low-density lipoprotein, and triglyceride (P<0.05) but not for high-density lipoprotein level. Conclusion. Serum lipids may have a role in producing angiogenic factors and development of cherry angioma and it seems logical to evaluate lipid profile in these cases.

scholarly journals Uji Toksisitas Ekstrak Metanolik Kombinasi Daun Benalu Teh Dan Daun Benalu Mangga Terhadap Profil Lipid Tikus Betina (Rattus norvegicus) pada Paparan Sub-Kronik 28 Hari

2020 ◽  
Vol 3 (1) ◽  
Author(s):  
Tengku Anggun Lestari ◽  
Nour Athiroh ◽  
Nurul Jadid Mubarakati
Keyword(s):  
High Density Lipoprotein ◽  
Lipid Profile ◽  
Total Cholesterol ◽  
Rattus Norvegicus ◽  
Toxicity Test ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
High Density ◽  
Low Density ◽  
One Way Anova

Tea Benalu (Scurrula atropurpurea [Bl.] Dans.) and Mango Benalu (Dendrophthoe pentandra L. miq.) containssecondary metabolites with potential antioxidant potential. Antioxidants can inhibit the oxidation process and reduce Total Cholesterol, Triglycerides, Low-Density Lipoprotein (LDL) and increase High-Density Lipoprotein (HDL). The safety of the preparations for the combination of parasites of tea and mango leaves was tested to obtain toxic effects after repeated treatment tests over some time. The purpose of this study was to determine the toxic effects of a combination of methanolic extracts of a combination of tea parasites and mangoes in female rats (Rattus norvegicus) subchronically for 28 days by looking at the results of the clinical biochemical examination on lipid profiles, namely total cholesterol levels, triglycerides, high-density lipoproteins (28%). HDL), and Low-Density Lipoprotein (LDL). The method of this study was experimental with a combination dose of methanol extract of tea parasite leaves and mango parasite leaves at a dose of 250 mg / KgBB, 500 mg / KgBB and 1000 mg / KgBB with 5x replications each treatment. The subjects used white rats (Rattus norvegicus) female Wistar strains aged 6-8 weeks with a minimum body weight of 100 grams. The treatment in this study was in the form of each dose given 5 times a week for 28 days (subchronic toxicity test) orally. Lipid profile levels were analyzed using the one-way ANOVA test. The results showed that the level of control blood lipid profile with a treatment dose of 250 mg / KgBW, 500 mg / KgBW, and 1000 mg / KgBW was not significantly different. The toxicity test of combined extracts of tea leaves and mango parasite leaves of female rat Rattus novergicus on subchronic exposure 28 days with those doses showed no difference tangible between treatments of controls. This means it is safe and does not cause toxic properties in the lipid profile of female wistar rats.Keywords: Lipid Profile, Scurrula atropurpurea, Dendophthoe pentandra, Sub-Chronic Toxicity, Rattus norvegicus ABSTRAKBenalu Teh (Scurrula atropurpurea [Bl.] Dans.) dan  Benalu Mangga (Dendrophthoe pentandra L. miq.) mengandung metabolit sekunder berpotensi sebagai antioksidan. Antioksidan dapat memperhambat proses oksidasi dan menurunkan Cholesterol Total, Trigliserida, Low Density Lipoprotein (LDL) dan menaikkan High Density Lipoprotein (HDL). Keamanan sediaan kombinasi daun benalu teh dan mangga diuji memperoleh tentang efek toksik setelah uji perlakuan berulang dalam jangka waktu tertentu. Tujuan dari penelitian ini untuk mengetahui efek toksik kombinasi ekstrak metanolik kombinasi daun benalu teh dan mangga pada tikus betina (Rattus norvegicus) secara subkronik selama 28 hari dengan melihat hasil pemeriksaan biokimia klinis pada profil lipid, yaitu kadar Cholesterol Total, Trigliserida, High Density Lipoprotein (HDL), dan Low Density Lipoprotein (LDL). Metode penelitian ini adalah eksperimental dengan perlakuan dosis kombinasi ekstrak metanol daun benalu teh dan daun benalu mangga dosis 250 mg/KgBB, 500 mg/KgBB dan 1000 mg/KgBB dengan ulangan 5x tiap perlakuan. Subjek menggunakan tikus putih (Rattus norvegicus) betina strain wistar yang berumur 6-8 minggu dengan berat badan minimal 100 gram. Perlakuan dalam penelitian ini berupa setiap dosis  diberikan 5 kali seminggu selama 28 hari (uji toksisitas subkronik) secara per-oral. Kadar profil lipid dianalisis menggunakan uji One-way ANOVA. Hasil penelitian menunjukkan bahwa kadar profil lipid darah kontrol dengan perlakuan dosis 250 mg/KgBB, 500 mg/KgBB dan 1000 mg/KgBB tidak berbeda nyata. Uji”toksisitas”ekstrak kombinasi daun benalu teh dan daun benalu mangga  tikus betina Rattus novergicus pada paparan subkronik 28 hari dengan”dosis”tersebut menunjukkan hasil tidak”beda”nyata antara perlakuan terhadap”kontrol. ”Hal ini berarti aman dan tidak menimbulkan sifat toksik pada profil lipid tikus wistar betina.Kata Kunci : Profil Lipid, Scurrula atropurpurea, Dendophthoe pentandra, Subkronik, Rattus norvegicus

scholarly journals Effect of Parkia biglobosa seed on lipid profile of dexamethasone-treated pregnant rats

2021 ◽  
Vol 8 (3) ◽  
pp. 030-039
Author(s):  
Funmilola Comfort Oladele ◽  
Bashirat Motunrayo Oluokun ◽  
Omotola Blessing Adam
Keyword(s):  
Lipid Profile ◽  
Plasma Glucose ◽  
Animal Feed ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Control Group ◽  
Low Density ◽  
Open Market ◽  
Parkia Biglobosa ◽  
Pregnant Rats

This study was aimed at evaluating the effect of Parkia biglobosa seed on dexamethasone-treated pregnant rats. Locust bean seeds were purchased from an open market in Ado Ekiti, Nigeria. It was processed and ground into powder which was subsequently used in formulating feed for experimental animals. Fifteen female pregnant rats were divided in three groups of five each. Animals in group A were exposed to standard animal feed only. This served as the control group. Those in group B were exposed to animal feed mixed with locust beans + 0.3 mg/kg body weight of dexamethasone, while those in group C were exposed to animal feed mixed with locust beans. At the end of eight days treatment, animals were sacrificed and blood sample was collected into EDTA bottles and centrifuged. Plasma was separated and used for the determination of glucose and lipid profile. Exposure of animals to dexamethasone was observed to significantly (p<0.05) increased the concentration of plasma glucose concentration when compared with the control as well as animals treated with P. biglobosa only. Animals treated with dexamethasone along with P. biglobosa were observed to have higher concentrations of triglyceride, total cholesterol, low density lipoprotein (LDL) and very low density lipoprotein (VLDL) when compared with those in animals in the control group as well as those treated with P. biglobosa only. Observations from this study revealed that dexamethasone adversely perturbed and unhinged plasma glucose and lipid profile in female pregnant rats while P. biglobosa-formulated diet was observed to be a potent hypoglycemic and hypolipidemic agent.

scholarly journals JUS PEPAYA (CARICA PAPAYA L) DAPAT MENURUNKAN KADAR LDL DAN KOLESTEROL TOTAL PADA USIA 40-70 TAHUN

2018 ◽  
pp. 153-161
Author(s):  
Junendri Ardian ◽  
Ari Natalia Probandari ◽  
K Kusnandar
Keyword(s):  
High Density Lipoprotein ◽  
Carica Papaya ◽  
Low Density Lipoprotein ◽  
Intervention Group ◽  
Density Lipoprotein ◽  
High Density ◽  
Control Group ◽  
Low Density ◽  
Post Test ◽  
Research Show

  ABSTRAK Hiperkolesterolemia merupakan suatu kondisi dimana kolesterol dalam darah meningkat melebihi ambang normal yang ditandai dengan meningkatnya kadar kolesterol total terutama Low Density Lipoprotein (LDL) dan diikuti dengan penurunan kadar High Density Lipoprotein (HDL) darah, Tujuan penelitian adalah menganalisis pengaruh pemberian asupan jus pepaya terhadap kadar LDL dan kolesterol total pada ibu rumah tangga usia 40-70 tahun yang menderita hiperkolesterolemia. Metode: Jenis penelitian ini merupakan penelitian true eksperimental dengan desain penelitian pre and post test with control group. Total subjek sebanyak 20 orang yang dibagi kedalam dua kelompok, yaitu Intervensi Jus pepaya dan kelompok kontrol. Hasil penelitian menunjukkan bahwa kadar kolesterol total pada kelompok jus pepaya mengalami penurunan yang bermakna (p<0,05). Sedangkan pada kelompok kontrol tidak bermakna (p>0,05). Kadar LDL pada kelompok jus pepaya mengalami penurunan yang bermakna (p<0,05). Sedangkan pada kelompok kontrol tidak bermakna (p>0,05). Kesimpulan jus pepaya (carica papaya l) dapat menurunkan kadar LDL (Low Density Lipoprotein) dan kolesterol total.   Kata kunci: jus pepaya, kolesterol total, LDL.       ABSTRACT Hypercholesterolemia is a conditions where cholesterol in the bloods increased beyond the normal standard, its showed with cholesterol total level’s was increased especially Low Density Lipoprotein (LDL) and followed by the decreasing of High Density Lipoprotein (HDL) in blood, The purpose of this research is analyzing the influence’s of papaya juice intake for LDL’s levels and cholestrol’s total at the age of 40 – 70 years old for housewives with hypercholesterolemia. The method this research is true experimental researchs with pre and post test control group designs. The subject in this research are 20 people and separated into two groups, the first group is papaya juice’s intervention group, and the second is control group. The result of this research show that papaya juice’s has significant result for decreasing cholesterol’s total with p value’s < 0,05 , while the control group has no significant result because its p value’s >0,05. The result for LDL’s levels show that papaya juice’s has significant result too for decreasing LDL’s levels with p value’s < 0,05, while the control group has no significant result because its p value’s >0,05. The conclusion in this research is papaya juice (carica papaya l) can decreased ldl’s levels and cholesterol’s total.   Keywords: cholesterol’s total, LDL, papaya juice.  

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