scholarly journals STRUCTURE OF SURGICAL ABNORMALITY IN NEWBORNS OF THE NIZHNY NOVGOROD REGION

Author(s):  
I. Yu. Karpova ◽  
V. V. Parshikov ◽  
E. A. Rozhdenkin ◽  
G. B. Batanov ◽  
V. E. Pivikov ◽  
...  

Introduction.A tendency to the decline in birth rate and reduced number of diseases of the neonatal period has been lately observed in the Nizhny Novgorod region.Materials and methods. 494 neonates with a surgical pathology aged from the frst hours to several weeks were treated in hospitals serving as clinical bases for the Volga Research Medical University from 2013 to 2017. 305 (62%) boys and 189 (38%) girls were observed. The majority of children (88%) were taken to surgical departments from maternity homes and perinatal centers of the city and region. 62 (12%) of children were hospitalized following the referral from local pediatricians. Admitted patients had a clinical and instrumental examination and initial therapy that stabilized their conditions and prepared them for surgeries.Results. Congenital malformations (CM) were diagnosed in 330 (67%) children only. According to analysis of diseases related to the neonatal period, purulent and septic processes were found in 104 (21%) patients. Surgeries were performed in children aged from day 1 to several months of life.Conclusion. Modern antenatal diagnostics and complex examination of newborns in the neonatal period enable timely detection of congenital abnormalities and initiation of adequate treatment.

2021 ◽  
Vol 76 (4) ◽  
pp. 341-350
Author(s):  
Sergey M. Voevodin ◽  
Tatiana V. Shemanaeva ◽  
Alyona V. Serova

Background.Oligohydramnion in the first half of pregnancy, combined with congenital abnormalities in the fetus has objective difficulties in diagnosis. The morphology features and type of defects associated with oligohydramnion, which manifests in the first half of pregnancy, are not sufficiently studied at the present stage. Aims to evaluate the clinical significance of diagnosing oligohydramnion in the first half of pregnancy in women with congenital fetal malformations. Materials and methods.The analysis of the course of pregnancy and perinatal outcomes in 77 women with low water content in combination with congenital malformations of the fetus and 72 patients with a normal amount of amniotic fluid and no congenital malformations of the fetus was performed. The patients of the main group were divided into two subgroups depending on the severity of oligohydramnion: the 1st subgroup (n = 54) patients with severe oligohydramnion and the 2nd subgroup (n = 23) patients with moderate oligohydramnion. The amount of amniotic fluid was determined by 3D/4D ultrasound (1321 weeks of gestation) and the structure of fetal abnormalities associated with oligohydramnion was analyzed. We evaluated perinatal outcomes in women with congenital malformations of the fetus in combination with oligohydramnion and the effect of its severity on the outcome of pregnancy. Results.In the main group (n = 77), fetal abnormalities were detected in patients: urinary system 39 (50.6%), respiratory system 4 (5.2%), heart 1 (1.3%), chromosomal and genetic abnormalities 14 (18.2%), central nervous system 3 (3.9%), osseous system 3 (3.9%), multiple 13 (16.9%). In the main group (n = 77), pregnancy was terminated for medical indications in 47 (61%) cases, in 6 (7.8%) spontaneous miscarriage occurred, in 5 (6.5%) antenatal fetal death. 19 (24.7%) children were born alive, and surgical treatment in the neonatal period was required in 8 (10.4%) cases. In the 1st subgroup (n = 54) in 53 (98.1%) cases, there was a loss of the fetus, in 1 (1.9%) the newborn died on the 9th day. In the 2nd subgroup (n = 23), fetal death occurred in 5 (21.7%) cases, 18 (78.3%) children were born alive, and 8 (44.4%) newborns were operated on in the neonatal period. In the control group, all pregnancies ended with the birth of healthy children. A decrease in ultrasound imaging of internal organs in the fetus was observed when a pregnant woman was obese (BMI more than 35). Conclusions.Oligohydramnion in the first half of pregnancy in combination with fetal malformation should be considered an extremely unfavorable clinical sign for the prognosis of pregnancy and the health of the fetus and newborn. 3D/4D ultrasound scanning allows you to reliably determine oligohydramnion in the first half of pregnancy, and the degree of its severity to assume the nature of complications.


PEDIATRICS ◽  
1964 ◽  
Vol 34 (5) ◽  
pp. 744-745
Author(s):  
RUSTIN MCINTOSH

This is a gem of a book—small, compact, sparkling, a bit expensive for its size. It reflects the growing interest in congenital defects and the realization that early identification is the key to successful correction in an increasing number and variety of anomalies. The author, consultant pediatrician to Alder Hey and Olive Mount Children's Hospitals in Liverpool, addresses himself to obstetrician and pediatrician alike, placing special emphasis on the conditions which can be recognized or suspected during the four weeks preceding birth and in the neonatal period.


2021 ◽  
pp. 8-11
Author(s):  
Kausik Sur ◽  
Brajagopal Ray

Introduction: Increasing number of Late Preterm (LPT) babies are being born in recent years, and they suffer from increased neonatal morbidities and moralities. Objective: +0 +6 To assess the immediate neonatal morbidities and mortalities of Late Pretrem - LPT - (34 -36 weeks) compared to +0 +6 +0 +6 those babies born at Early Term -ET- (37 - 38 weeks) and Term - T- (39 - 40 weeks) gestation. Methodology: A retrospective review of delivery, admission, discharge and death registers and necessary case notes of all live in-born babies excluding those with congenital anomalies were done in RKM Seva Pratisthan Hospital, a teriray level University Hospital in the City of Kolkata, between 1st January 2018 till 31st December 2019. Data collected in a predesigned pro forma were analysed with SPSS vs 23 software, after obtaining necessary permission. All the major neonatal morbidities and morality were compared between the three groups. Results: +0 +6 Total 6511 babies born between gestation 34 and 40 weeks were analysed of which 1021 were in LPT group (31.9%requiring NICU admission), 3408 in ET group (8.3% requiring NICU admission) and 2068 in T group (9.2% requiring NICU admission). There was no signicant difference in mortality (LPT vs ET vsT : 0.5% vs 0.3% vs 0.1%). All the major morbidities ( Respiratory, CNS, Infectious, Metabolic and Any morbidity) were signicantly higher in LPT group. No signicant difference were observed between ET and Term group in terms of any neonatal morbidity or mortality. Conclusion: Late Pretrem newborns suffer from increased neonatal morbidity compared to their Early Term or Term counterpart in immediate neonatal period. No difference of morbidity or mortality were noted between Early Term and Term groups.


JURTEKSI ◽  
2021 ◽  
Vol 8 (1) ◽  
pp. 85-94
Author(s):  
Muhammad Jufri

Abstract: The population growth in Indonesia is increasing rapidly every year, so to help the government control the population growth through family planning programs, especially in the city of Batam. This study explains and describes one of the Artificial Terms Network methods, namely Backpropagation, where this method can predict what will happen in the future using data and information in the past. This study aims to predict the birth rate in the city of Batam to help the government with the family planning program. The data used is the annual data on the number of births in the city of Batam in 2016-2020 at The Civil Registry Office. To facilitate the analysis of research data, the data were tested using Matlab R2015b. In this study, the training process was carried out using 3 network architectures, namely 4-10-1, 5-18-1, and 4-43-1. Of these 3 architectures, the best is the 4-43-1 architecture with an accuracy rate of 91% and an MSE value of 0.0012205. The Backpropagation method can predict the amount of population growth in the city of Batam based on existing data in the past.           Keywords: artificial neural network; backpropagation; prediction   Abstrak: Pertumbuhan jumlah penduduk diindonesia yang setiap tahun meningkat dengan pesat, maka untuk membantu pemerintah mengendalikan jumlah pertumbuhan penduduk melalui program keluarga berencana khususnya dikota Batam. Penelitian ini  menjelaskan dan memaparkan tentang salah satu metode Jaringan Syarat Tiruan yaitu Backpropagation, dimana metode ini dapat memprediksi apa yang akan terjadi masa yang akan datang dengan menggunakan data dan informasi dimasa lalu. Penelitian ini bertujuan untuk memprediksi tingkat kelahiran di kota Batam sehingga membatu pemerintah untuk perencanaan keluarga berencana. Data yang digunakan yaitu data tahunan jumlah kelahiran di kota Batam pada tahun 2016-2020 pada Dinas Kependudukan dan Catatan Sipil. Untuk mempermudah analisis data penelitian maka, data diuji menggunakan Matlab R2015b. Pada penelitian ini dilakukan proses pelatihan menggunakan  3 arsitektur jaringan yaitu 4-10-1, 5-18-1, dan 4-43-1. Dari ke-3 arsitektur ini yang terbaik adalah arsitektur 4-43-1 dengan tingkat akurasi sebesar 91% dan nilai MSE 0,0012205. Metode backpropagation mampu memprediksi jumlah pertumbuhan penduduk di kota Batam berdasarkan data yang ada dimasa lalu. Kata kunci: backpropagation; jaringan syaraf tiruan; prediksi 


10.3823/2465 ◽  
2017 ◽  
Vol 10 ◽  
Author(s):  
Rosana Alves de Melo ◽  
Flávia Emília Cavalcante Valença Fernandes ◽  
Ana Kariny Costa Araújo ◽  
Nadja Maria dos Santos ◽  
Maria Elda Alves de Lacerda Campos ◽  
...  

Objective: To evaluate the neonatal morbidity due to congenital malformations in the city of Petrolina-PE, from 2008 to 2013. Methods: A descriptive study with data from the Information System on Live Births (Sinasc). The analyzes were carried out through frequency distribution and measures of central tendency and dispersion. The associations were tested by the Pearson and Kruskal Wallis chi-square tests. Significance was set at 5% and 95% confidence. Results: 436 cases of congenital malformations were recorded in the study period, with 2011 being the highest occurrence year. The mothers of the newborns were young (25.2 years old), single, upper level of education and household. In general multiparous, with single gestation, vaginal delivery and performed up to six prenatal visits. The newborns were males, at 39 weeks or more of gestation and with normal weight (> = 2500g). The malformations of the musculoskeletal system were the most frequent followed by the genitourinary system. Congenital malformations were especially associated with neonatal characteristics such as gender and weight. In all causes the mean weight was greater than 2500g (p <0.05). The causes of malformation of greater occurrence in both sexes were osteomuscular (p <0.05). The aspects of the mother did not present significant differences in the present study (p> 0.05). Conclusion: The present study evidenced relevant aspects in the occurrence of morbidities due to congenital malformations, directing to a greater attention the occurrence of these diseases especially in relation to the newborn.


Author(s):  
O. Lanovenko

Background. In Ukraine, the unfavorable demographic situation makes monitoring of the birth rate of children with congenital malformations urgent issue to identify regional features of epidemiology and develop methods for prenatal diagnosis and prognosis. Objective. Objective of this study is to characterize the frequency dynamics, to identify structural features of congenital malformations of newborns in Kherson region over a 20-year period (2000-2019) and to compare the prevalence of various nosological forms of malformations in the region, in Ukraine and in European countries. Methods. Research methods: epidemiological, medical-statistical. Results. In Kherson region, the average frequency of congenital malformations over the past 20 years is: for newborns – 31.57±1.25‰; for live births – 31.38±1.11‰; for stillborns – 197.7±0.65 per 10,000. In the structure of defects, cardiovascular malformations are leading (31.77%), musculoskeletal malformations (25.14%), genital malformations (17.5%). Increased prevalence of developmental anomalies in the region is mainly associated with an increase in the frequency of model malformations recorded by EUROCAT (r=0.69, p<0.05). The increase in the total frequency of congenital malformations is caused by increased number of births of children with cardiovascular defects (by 4.67‰), genital defects (by 1.21‰), other congenital malformations (by 1.55‰), multiple malformations (by 0.37‰). Conclusion. Monitoring results showed an increase in congenital malformations incidence in Kherson region over a 20-year period by 7.94‰ possibly caused by population decline due to negative natural and mechanical growth. The prevalence of hereditary defects is at the same level. The frequency of some nosological forms significantly exceeds in the region compare to that in Ukraine and Europe: cardiovascular defects – in 1.5 times, genital malformations – in nearly 3 times, musculoskeletal defects – almost twice.


2019 ◽  
Vol 72 (5) ◽  
pp. 1136-1139
Author(s):  
Tetiana V. Pluzhnikova ◽  
Oksana I. Krasnovа ◽  
Svitlana S. Kasinets ◽  
Svitlana M. Tanyanskaya ◽  
Natalia V. Yaroshenko ◽  
...  

Introduction: Providing high-quality health care to the newborn is part of the national health system. The number of healthy children in Ukraine decreases annually. One of the main directions of development of the pediatric service is reduction of indicators of child mortality, increase of birth rate and strengthening of children’s health. The aim: To analyze the dynamics of morbidity and causes of infant mortality in the city of Poltava. Materials and methods: Medical and statistical - for collecting, processing and analyzing data, (descriptive and analytical statistics for determining relative indicators, absolute growth indicators), a systems approach and system analysis. Review: According to a study in the city of Poltava, there is a negative absolute increase in the birth rate of children. In the structure of the causes of death of the child population in the first place are the diseases of the period of birth of the newborn, in the second place - congenital anomalies of development. The third place in the structure of causes of death is occupied by diseases of the central nervous system. There is a clear decrease in the incidence of hemolytic disease, anemia, cardiac disorders, intrauterine hypoxia and asphyxiation. In the structure of birth injuries in newborns occupy closed clavicle fractures, plexitis of the newborn. Conclusions: Analysis of the incidence and causes of infant mortality in the city of Poltava suggests that in recent years there has been a decrease in fertility rates, an increase in morbidity rates. The reform should be aimed at improving the state of the pediatric service and the prevention of preterm labor.


PEDIATRICS ◽  
1989 ◽  
Vol 83 (5) ◽  
pp. 785-789
Author(s):  
D. A. FISHER ◽  
B. L. FOLEY

Mass population screening of newborn infants for congenital hypothyroidism was introduced in 1974 and now is a routine and effective means of early diagnosis of congenital hypothyroidism throughout most of the industrialized world. A large number of affected infants and children have been treated with replacement thyroid hormone, and several reports of IQ measurements and functional assessments of 5-to 7-year-old treated children now are available. These reports document normal mean IQ values, satisfactory school performance, and minimal motor dysfunction in treated children. However, there have been reported correlations between lower IQ values and biologic parameters of the hypothyroid state in the neonatal period among several reported studies, and it is not yet clear whether early adequate treatment will reverse all of the effects of congenital hypothyroidism.


Animals ◽  
2020 ◽  
Vol 10 (9) ◽  
pp. 1532
Author(s):  
Di Muro G. ◽  
Cagnotti G. ◽  
Bellino C. ◽  
Capucchio M.T. ◽  
Colombino E. ◽  
...  

Congenital malformations of the central nervous system (CNS) can affect the CNS alone or the CNS and craniofacial structures. Here, we report an unusual and complex congenital cephalic malformation observed in a 3-day-old male crossbreed calf. Clinical examination disclosed a dome-shaped cranial vault, a flat face with a short snout, a median cleft lip, and increased intraorbital distance. The frontal region of the head was remarkable for a fluctuant, sac-like protrusion covered with haired skin. Neurologic findings suggested a multifocal intracranial lesion affecting the prosencephalon and the central vestibular system. While pathological and histopathological findings posited for a presumptive diagnosis of either hydranencephaly or holoprosencephaly associated with multiple congenital facial abnormalities, not all the findings could be definitely attributed to either of the two encephalic malformations alone. To our knowledge, a similar combination of severe congenital abnormalities affecting both the CNS and the craniofacial structures has not been reported in calves to date.


Sign in / Sign up

Export Citation Format

Share Document