scholarly journals A review on scientific technologies in practice to innovate plant based molecules and to improve herbal drug quality to overcome health problems

2010 ◽  
Vol 2 (1) ◽  
pp. 165-181 ◽  
Author(s):  
K.K. Gupta ◽  
G. Khandelwal ◽  
G. Prasad ◽  
A.K. Chopra ◽  
A. Mishra

Medicines obtained from drug plants and other sources are commonly called traditional medicines. They have played an important role in the treatment of several human diseases since ancient times. India possessed a great wealth of traditional health care system known as Ayurveda related to the use of plant species. The global market of herbal drugs has a great potential around the world. Demand of plant based medicines is also increasing among western countries because of a general consideration that most allopathic drugs are associated with more or less side effects. Many pharmaceutical companies are now manufacturing Ayurvedic phytopharmaceutical products. However, enough efforts have not been made to get suitable substitute of modern allopathic medicines from these traditionally used drug plants and herbal drugs. This traditional system of healthcare in India still needs extensive evidence-based scientific researches in promoting its therapies. This review paper deals with modern scientific approaches to find out new plant based molecules and to develop new technologies in a continuous process and should be applied in the practice to improve the quality of herbal drugs in Indian pharmaceutical industries. Critical assessment of quality assurance including researches on pharmacognosy, chemistry, pharmacology, antimicrobial activity and clinical studies carried out on various Ayurvedic medicinal plants are also being presented.

Author(s):  
NUZHAT TABASSUM ◽  
VIDYASAGAR G. M.

Objective: The aim of the study was to isolate alkaloid compound from seed oil of Derris indica (Lam) Bennett where relevant antimicrobial properties in traditional medicines. Methods: The plant was selected based on their usage in traditional medicines and ethnopharmacological importance. Crude extract from D. indica seeds fractioned with different solvents through column chromatography. Isolated pure fraction was identified and characterized using UV, FTIR, 1HNMR and Mass spectroscopy. Results: D. indica seeds hexane extract on fractionation with ethyl acetate and methanol through column chromatography yielded a crystalline fraction. The fraction was identified as alkaloid group and characterized as a 2-(6-methoxyphenanthridin-8-yl) propan-2-ol. The compound is a new report from D. indica seed oil. Conclusion: The usage of D. indica plant is much in traditional health care for treatment of diseases. Isolation of alkaloid compound from D. indica seeds in traditional herbal medicines may be found a good source of drug discovery.


Author(s):  
Tejinder Pal Kaur

Background: Among the primitive tribe of Jharkhand, Birhor’s are the smallest group, and have been tagged as 'critically endangered' with population ~5000 (Census 2011). Traditional health care practices, traditional medicines, rituals and supernatural methods of treatment are integral part of tribal community. The main objective of the study was to integrate the cultural health practices focusing on reproductive health with modern medicine so that it impacts maternal and infant mortality.Methods: A three- and half-year study was done in one of the outreach clinical area of Tata Steel Rural development society in Chotabanki village, East Singhbhum, Jharkand, India, among the Birhor tribes.  The study was based on primary quantitative data -Data collection was by interviewing the respondents using questionnaires. Numerous interactive sessions with community members were conducted to learn about their cultural practices related to maternal and infant health.Results: There was a definite change in behaviour in some of traditional health practices, related to maternal and child health. Acceptance of modern health services impacted the health indicators, resulting in increase in population growth by 7.6% with zero still birth, maternal and infant mortality.Conclusions: As medical professionals, extra effort should be taken to understand their cultures regarding health. By establishing a balance between their age-old cultural practices and modern medicine, we may get healthier and résistance free community & success in controlling morbidity and mortality.


2020 ◽  
Vol 11 (SPL1) ◽  
pp. 1116-1121
Author(s):  
Pooja P. Thakre ◽  
Vinod Ade ◽  
Shweta Parwe

Coronavirus disease (CoViD-19) is an infection of the respiratory system caused due to various viruses affects the respiratory pathway, and it can spread from one person to another by coughing, sneezing or physical contact. Commonly include cough, cold, fever are the symptoms. Viral diseases increase worldwide concern, including emerging and chronic viruses. The invention of new anti-viral drugs from plants has implicit in the past. The Coronavirus disease 19 (COVID-19) caused due to severe acute respiratory syndrome, which is a transmittable and pathogenic viral infection. Several traditional medicines of plant origin having antimicrobial and anti-inflammatory properties some have been studied for their anti-viral properties and immune-modulating effects. Herbal drugs are now in massive requirement in the developing countries for primary health care not because of their economical but also for better civilising adequacy, improved compatibility with the human body and significantly fewer side effects. This review gives an overview of some critical traditionally used medicinal herbs with anti-viral properties—the literature regarding the drugs of this group, collected from Ayurveda classics. Research articles are collected from published material and discussed per therapeutic actions. Most of the Herbs are with Katu Rasa (pungent) and Ushna Virya (hot potency). They are indicated in diseases, viz. Kasa (cough), Shwas (asthma), Krumi (worm/ infection). Krumihara property drugs which are correlated with anti-viral action helps to prevent against Novel coronavirus infection.


2020 ◽  
Vol 4 (2) ◽  
Author(s):  
Danar Agus Susanto

ABSTRACTIndonesia is the world's largest producer of crude palm oil (CPO). Even so, the trend of international trade in Indonesian CPO products has decreased in the last 10 years with a value of -10.19%. The decline in world demand for CPO can be dealt with by utilizing CPO as a biofuel for domestic use, like biodiesel. The purpose of this study is to determine the competitiveness of Indonesian CPO in global trade and determine the parameters of the quality requirements of CPO and biodiesel. The competitiveness analysis method uses the Revealed Comparative Advantage (RCA) method, while the analysis of the potential quality of CPO as a biofuel is carried out by analyzing the Indonesian National Standard (SNI). CPO trade in the global market is controlled by Indonesia with a market share of 50% and Malaysia 25.6%, with the declining trade trend in the last 10 years relatively (2010-2019) of -6.91%. The level of competitiveness of Indonesian CPO products in 2019 is very strong, but on average in the last 10 years, the level of competitiveness of Indonesian CPO is no better than that of Malaysia. Indonesia has SNI 01-2901-2006 and SNI 7182: 2015 as a determinant of the quality of CPO and biodiesel products developed in Indonesia so that the CPO and biodiesel produced fullfil sacurity and safety aspects when used by consumers.Keywords: crude palm oil (CPO), competitivenessv, quality, Indonesian National Standard (SNI) ABSTRAKIndonesia merupakan negara produsen minyak kelapa sawit mentah/ Crude Palm Oil (CPO) terbesar di dunia. Meskipun demikian, tren perdagangan internasional produk CPO Indonesia mengalami penurunan dalam sepuluh tahun terakhir dengan nilai -10,19%. Penurunan permintaan dunia terhadap CPO, dapat disiasati dengan memanfaatkan CPO sebagai bahan bakar nabati untuk keperluan dalam negeri sebagai biodiesel. Tujuan penelitian ini adalah mengetahui daya saing CPO Indonesia dalam perdagangan global dan mengetahui parameter persyaratan mutu CPO dan biodiesel. Metode analisis daya saing menggunakan metode Revealed Comparative Advantage (RCA), sedangkan analisis potensi kualitas CPO sebagai biofuel dilakukan dengan menganalisis Standar Nasional Indoensia (SNI). Perdagangan CPO dalam pasar global dikuasai oleh Indonesia dengan pangsa pasar 50% dan Malaysia 25,6%, dengan tren perdagangan relatif menurun dalam 10 tahun terakhir (2010-2019) sebesar -6,91%. Tingkat daya saing produk CPO Indonesia pada tahun 2019 sangat kuat, namun secara rata-rata dalam 10 tahun terakhir, tingkat daya saing CPO Indonesia tidak lebih baik dari Malaysia. Indonesia memiliki SNI 01-2901-2006 dan SNI 7182:2015 sebagai penentu kualitas produk CPO dan biodiesel yang dikembangkan di Indonesia, sehingga CPO dan biodiesel yang dihasilkan memenuhi aspek keamanan dan keselamatan ketika digunakan oleh konsumen.Kata kunci: crude palm oil (CPO), daya saing, kualitas, Standar Nasional Indonesia (SNI)


Author(s):  
Adithya J ◽  
Bhagyalakshmi Nair ◽  
Aishwarya S ◽  
Lekshmi R. Nath

: SARS-CoV 2 is a novel virus strain of Coronavirus, reported in China in late December 2019. Its highly contagious nature in humans has prompted WHO to designate the ongoing pandemic as a Public Health Emergency of International Concern. At this moment, there is no specific treatment and the therapeutic strategies to deal with the infection are only supportive, and prevention aimed at reducing community transmission. A permanent solution for the pandemic, which has brought the world economy to the edge of collapse, is the need of the hour. This situation has brought intense research in traditional systems of medicine. Indian Traditional System, Ayurveda has a clear concept of the cause and treatment of pandemics. Through this review, information on the potential antiviral traditional medicines along with their immunomodulatory pathways is discussed. We have covered the seven most important Indian traditional plants with antiviral properties :Withaniasomnifera (L.) Dunal(family: Solanaceae),Tinosporacordifolia(Thunb.)Miers (family:Menispermaceae),Phyllanthusemblica L.(family:Euphorbiaceae),Asparagus racemosus L.(family:Liliaceae), Glycyrrhizaglabra L.(family:Fabaceae), Ocimum sanctum L.(family:Lamiaceae) and Azadirachta indica A.Juss(family:Meliaceae)in this review. An attempt is also made to bring into limelight the importance of dietary polyphenol, Quercetin which is a potential drug candidate in the making against the SARS-CoV2 virus.


2021 ◽  
pp. 2455328X2199571
Author(s):  
Manisha Thapa ◽  
Pinak Tarafdar

In all cultures and regions, the concept of health varies, based on the type of environment and prevalent sociocultural traditions. The present study is conducted among the Lepchas of the village of Lingthem divided into two sectors—Upper and Lower Lingthem, Upper Dzongu, North Sikkim. This population comprising Buddhist Lepchas residing away from the mainstream through poor infrastructural facilities still maintain ethnomedical health care practices without influence of major Indian healing systems. Living in the area of Dzongu exclusively inhabited by Lepchas revival of ancient cultural practices is evident among Lepchas of Lingthem. The structure of religious beliefs prevalent among the Lepchas, including traditional animistic as well as Buddhist practices, greatly influence forms of treatment sought for specific ailments. Even today, the use and maintenance of traditional health care with syncretized Buddhist religious belief among residents of Lingthem act as a vital source for understanding the influence of religion on traditional health care practices. Despite the presence of a few modern health care agencies, the traditional treatment of Bongthing (Lepcha shaman) and Buddhist monks remain widely popular as primary means of health care.


PEDIATRICS ◽  
1992 ◽  
Vol 89 (5) ◽  
pp. 920-924
Author(s):  
John D. Lantos ◽  
Arthur F. Kohrman

This essay is a discussion of ethical issues that arise in the provision of home health care to technology-dependent children. Different ethical norms, especially with regard to the degree of professional responsibility for outcomes, traditionally have applied to home care and hospital care. In particular, parents generally are expected to do their best, but are not expected to have the same specialized knowledge of risks and benefits with regard to particular interventions as health professionals. When home health care involves the use of advanced medical technology, it strains traditional conceptions of parental responsibilities to care for the health of their children at home. It can also strain traditional concepts of professional responsibilities to care for critically ill children in hospitals. We discuss some of the tensions that arise as medical, psychological, and economic forces lead to the increasing use of high technology in the care of children outside of traditional health care institutions.


2017 ◽  
Vol 19 (4) ◽  
pp. 621-628 ◽  
Author(s):  
Mary V. Greiner ◽  
Sarah J. Beal

In 2012, the Comprehensive Health Evaluations for Cincinnati’s Kids (CHECK) Center was launched at Cincinnati Children’s Hospital Medical Center to provide health care for over 1,000 children placed into foster care each year in the Cincinnati community. This consultation model clinical program was developed because children in foster care have been difficult to manage in the traditional health care setting due to unmet health needs, missing medical records, cumbersome state mandates, and transient and impoverished social settings. This case study describes the history and creation of the CHECK Center, demonstrating the development of a successful foster care health delivery system that is inclusive of all community partners, tailored for the needs and resources of the community, and able to adapt and respond to new information and changing systems.


2020 ◽  
pp. 1-7
Author(s):  
Sumit Kumar Gupta ◽  

Nanotechnology is new frontiers of this century. The world is facing great challenges in meeting rising demands for basic commodities(e.g., food, water and energy), finished goods (e.g., cellphones, cars and airplanes) and services (e.g., shelter, healthcare and employment) while reducing and minimizing the impact of human activities on Earth’s global environment and climate. Nanotechnology has emerged as a versatile platform that could provide efficient, cost-effective and environmentally acceptable solutions to the global sustainability challenges facing society. In recent years there has been a rapid increase in nanotechnology in the fields of medicine and more specifically in targeted drug delivery. Opportunities of utilizing nanotechnology to address global challenges in (1) water purification, (2) clean energy technologies, (3) greenhouse gases management, (4) materials supply and utilization, and (5) green manufacturing and hemistry. Smart delivery of nutrients, bio-separation of proteins, rapid sampling of biological and chemical contaminants, and nano encapsulation of nutraceuticals are some of the emerging topics of nanotechnology for food and agriculture. Nanotechnology is helping to considerably improve, even revolutionize, many technology and Industry sectors: information technology, energy, environmental science, medicine, homeland security, food safety, and transportation, among many others. Today’s nanotechnology harnesses current progress in chemistry, physics, materials science, and biotechnology to create novel materials that have unique properties because their structures are determined on the nanometer scale. This paper summarizes the various applications of nanotechnology in recent decades Nanotechnology is one of the leading scientific fields today since it combines knowledge from the fields of Physics, Chemistry, Biology, Medicine, Informatics, and Engineering. It is an emerging technological field with great potential to lead in great breakthroughs that can be applied in real life. Novel Nano and biomaterials, and Nano devices are fabricated and controlled by nanotechnology tools and techniques, which investigate and tune the properties, responses, and functions of living and non-living matter, at sizes below100 nm. The application and use of Nano materials in electronic and mechanical devices, in optical and magnetic components, quantum computing, tissue engineering, and other biotechnologies, with smallest features, widths well below 100 nm, are the economically most important parts of the nanotechnology nowadays and presumably in the near future. The number of Nano products is rapidly growing since more and more Nano engineered materials are reaching the global market the continuous revolution in nanotechnology will result in the fabrication of nanomaterial with properties and functionalities which are going to have positive changes in the lives of our citizens, be it in health, environment, electronics or any other field. In the energy generation challenge where the conventional fuel resources cannot remain the dominant energy source, taking into account the increasing consumption demand and the CO2 .Emissions alternative renewable energy sources based on new technologies have to be promoted. Innovative solar cell technologies that utilize nanostructured materials and composite systems such as organic photovoltaic offer great technological potential due to their attractive properties such as the potential of large-scale and low-cost roll-to-roll manufacturing processes


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