scholarly journals Medical conditions and medication use in adults with Down syndrome: A descriptive analysis

2008 ◽  
Vol 12 (2) ◽  
pp. 141-147 ◽  
Author(s):  
Gerard Kerins ◽  
Kimberly Petrovic ◽  
Mary Bruder ◽  
Cynthia Gruman
Keyword(s):  
Down Syndrome ◽  
Descriptive Analysis ◽  
Medication Use ◽  
Medical Conditions

scholarly journals Preventable adverse drug events causing hospitalisation: identifying root causes and developing a surveillance and learning system at an urban community hospital, a cross-sectional observational study

2021 ◽  
Vol 10 (1) ◽  
pp. e001161
Author(s):  
Jane de Lemos ◽  
Peter Loewen ◽  
Cheryl Nagle ◽  
Robert McKenzie ◽  
Yong Dong You ◽  
...  
Keyword(s):  
Observational Study ◽  
Adverse Drug Events ◽  
Healthcare Providers ◽  
Medication Use ◽  
Learning System ◽  
Chronic Obstructive ◽  
Action Plans ◽  
Medical Conditions ◽  
Cross Sectional ◽  
Medication Changes

ObjectivesTo identify root causes of preventable adverse drug events (pADEs) contributing to hospital admission; to develop key messages which identify actions patients/families and healthcare providers can take to prevent common pADEs found; to develop a surveillance learning system for the community.MethodsCross-sectional observational study; 120 patients and families, 61 associated healthcare providers were interviewed then root cause analysis was performed to develop key learning messages and an electronic reporting tool was designed. Most common pADE-related medical conditions and their root causes and most common pADE root causes of entire cohort are reported.ResultsMost common pADE-related medical conditions: chronic obstructive pulmonary disease/asthma (13.3%), bleeding (12.5%), hypotension (12%), heart failure (10%), acute kidney injury (5%) and pneumonia (5%). Most common root causes were: providers not confirming that the patient/family understands information given (29.2%), can identify how a medication helps them/have their concerns addressed (16.7%), can identify if a medication is working (14.1%) or causing a side effect (23.3%); can enact medication changes (7.5%); absence of a sick day management plan (12.5%), and other action plans to help patients respond to changes in their clinical status (10.8%); providers not assessing medication use and monitoring competency (19.2%). Ten key learning messages were developed and a pADE surveillance learning system was implemented.ConclusionsTo prevent pADEs, providers need to confirm that patients/families understand information given, how a medication helps them, how to recognise and respond to side effects, how to enact medication changes and follow action plans; providers should assess patient’s/families’ medication use and monitoring competency.

scholarly journals Prevalence and profile of congenital heart disease and pulmonary hypertension in Down syndrome in a pediatric cardiology service

2014 ◽  
Vol 32 (2) ◽  
pp. 159-163 ◽  
Author(s):  
Felipe Alves Mourato ◽  
Lúcia Roberta R. Villachan ◽  
Sandra da Silva Mattos
Keyword(s):  
Congenital Heart Disease ◽  
Pulmonary Hypertension ◽  
Down Syndrome ◽  
Heart Disease ◽  
Congenital Heart ◽  
Septal Defect ◽  
Heart Diseases ◽  
Heart Defects ◽  
Descriptive Analysis ◽  
Atrioventricular Septal Defect

OBJECTIVE:To determine the frequence and profile of congenital heart defects in Down syndrome patients referred to a pediatric cardiologic center, considering the age of referral, gender, type of heart disease diagnosed by transthoracic echocardiography and its association with pulmonary hypertension at the initial diagnosis.METHODS:Cross-sectional study with retrospective data collection of 138 patients with Down syndrome from a total of 17,873 records. Descriptive analysis of the data was performed, using Epi-Info version 7.RESULTS: Among the 138 patients with Down syndrome, females prevailed (56.1%) and 112 (81.2%) were diagnosed with congenital heart disease. The most common lesion was ostium secundum atrial septal defect, present in 51.8%, followed by atrioventricular septal defect, in 46.4%. Ventricular septal defects were present in 27.7%, while tetralogy of Fallot represented 6.3% of the cases. Other cardiac malformations corresponded to 12.5%. Pulmonary hypertension was associated with 37.5% of the heart diseases. Only 35.5% of the patients were referred before six months of age.CONCLUSIONS: The low percentage of referral until six months of age highlights the need for a better tracking of patients with Down syndrome in the context of congenital heart disease, due to the high frequency and progression of pulmonary hypertension.

scholarly journals Risk of Multiple Myeloma following Medication Use and Medical Conditions: A Case-Control Study in Connecticut Women

2006 ◽  
Vol 15 (12) ◽  
pp. 2342-2347 ◽  
Author(s):  
Ola Landgren ◽  
Yawei Zhang ◽  
Sheila Hoar Zahm ◽  
Peter Inskip ◽  
Tongzhang Zheng ◽  
...  
Keyword(s):  
Multiple Myeloma ◽  
Case Control Study ◽  
Medication Use ◽  
Case Control ◽  
Medical Conditions ◽  
Control Study

Co-occurring medical conditions in adults with Down syndrome: A systematic review toward the development of health care guidelines

2017 ◽  
Vol 176 (1) ◽  
pp. 116-133 ◽  
Author(s):  
George T. Capone ◽  
Brian Chicoine ◽  
Peter Bulova ◽  
Mary Stephens ◽  
Sarah Hart ◽  
...  
Keyword(s):  
Systematic Review ◽  
Health Care ◽  
Down Syndrome ◽  
Medical Conditions ◽  
Care Guidelines

Motor Development in Children with Down Syndrome: A Review of the Literature

1991 ◽  
Vol 8 (3) ◽  
pp. 179-209 ◽  
Author(s):  
Martin E. Block
Keyword(s):  
Down Syndrome ◽  
Motor Development ◽  
Future Research ◽  
Medical Conditions ◽  
Review Of The Literature ◽  
Children With Down Syndrome ◽  
Extant Literature ◽  
Sensory Deficits ◽  
The Past ◽  
The Relationship

The effects of Down syndrome (DS) on motor development have been widely reported over the years, particularly with the profusion of research in the past 10 years. Although more research is needed to fully understand the relationship between DS and motor development, there is a need to synthesize the current findings. Henderson (1985, 1986) and Reid (1985) reviewed the literature regarding the motor development of children with DS. While Henderson’s review was extremely well done, certain recent studies can add to our understanding of the motor characteristics of these children. Furthermore, Henderson did not examine factors such as cardiac, anatomical, and sensory deficits that can affect motor development. Therefore this paper reviews the extant literature regarding the motor development of children with DS in terms of health and medical conditions that can affect this development as well as the motor development of infants and all others with DS. Finally, implications for future research and programming are discussed.

Psychotropic Medication Use in Children and Adolescents With Down Syndrome

2015 ◽  
Vol 36 (8) ◽  
pp. 613-619 ◽  
Author(s):  
Alison Downes ◽  
Julia S. Anixt ◽  
Anna J. Esbensen ◽  
Susan Wiley ◽  
Jareen Meinzen-Derr
Keyword(s):  
Down Syndrome ◽  
Children And Adolescents ◽  
Psychotropic Medication ◽  
Medication Use

scholarly journals Medical status of patients presenting for treatment at an Australian dental institute: A cross-sectional study

2020 ◽  
Author(s):  
Agnieszka Monika Frydrych ◽  
Richard Parsons ◽  
Omar Kujan
Keyword(s):  
Mental Health ◽  
Dental Treatment ◽  
Medical Condition ◽  
Medication Use ◽  
Extended Period ◽  
Health Condition ◽  
Medical Conditions ◽  
Tertiary Institution ◽  
Cross Sectional ◽  
Western Australian

Abstract Background: Individuals seeking dental treatment often present with medical conditions which may affect dental treatment provision. The purpose of this study was to determine the prevalence of medical conditions and medication use among individuals attending dental clinics at a Western Australian tertiary institution.Methods: This observational study examined the general demographics, medical and social histories of 873 subjects presenting for a general dental examination at a Western Australian Tertiary Institution between March 2018 and February 2019. Individual recruited were those presenting to the clinics either as new patients to the Centre or returning patients after an extended period of absence.Results: Presence of a medical condition was reported by 86% of the participants, with males more commonly affected (p=0.0448). Medication use was noted by 80% of the participants. Cardiovascular disease (37.9%), allergy (32.3%), mental health disorders (29.4%), musculoskeletal (23.0%), endocrine (22.4%) and respiratory disease (17.8%) were the most common conditions identified. Women were significantly more likely to report allergy (p=0.0002) or a mental health condition (p=0.0368). Conclusions: Medical comorbidities are common among individuals presenting for student dental treatment in Western Australia, highlighting the importance of knowledge and teaching of internal medicine and its application to the dental setting.

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