Hearing loss and diabetes mellitus: Evidences of cochlear microangiopathy?

Background: Diabetes Mellitus (DM) is a common metabolic disorder with a prevalence of 11.77%. Studies report that DM can result in Sensorineural hearing loss (SNHL). A high prevalence of Hearing loss (HL) (43.6%) in diabetics was noted in an Indian study. In absence of local studies and a high expected prevalence, with no screening recommendations, this study was carried out to determine the prevalence of Sensorineural Hearing Loss (SNHL) in Diabetes Mellitus DM in Southern Punjab. Methodology: In this cross-sectional study, a sample of 310 diabetics, hailing from southern Punjab and fulfilling selection criteria were recruited. Samples were collected using probability sampling technique from September 2016 to December 2016. Following detailed history and examination, cases were subjected to pure tone audiometry (PTA) at 0.5 to 6 KHz to obtain hearing thresholds to determine the prevalence. Data was analyzed by SPSS 20. Results: Sample included N=310 diabetics with Mean age of 35.00 + 6.93 years with 58.39% males and 41.61% females. The prevalence of HL was 46.1%. Gender wise of the male population with HL, 27.97% and 28.67% had mild and moderate HL respectively with severe HL in 8.39% cases, while moderate HL was prevalent in females 20.98%, followed by mild HL in 9.97% and severe HL in 4.20%. There was significant correlation between Diabetes and SNHL with p-value < 0.05. Conclusion: There is a high prevalence of sensorineural hearing loss in Diabetes mellitus.

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Metformin decreases the risk of sudden sensorineural hearing loss in patients with diabetes mellitus: A 14-year follow-up study

Diabetes and Vascular Disease Research ◽

10.1177/1479164119826292 ◽

2019 ◽

Vol 16 (4) ◽

pp. 324-327 ◽

Cited By ~ 4

Author(s):

Hsin-Chien Chen ◽

Chi-Hsiang Chung ◽

Chieh-Hua Lu ◽

Wu-Chien Chien

Keyword(s):

Diabetes Mellitus ◽

Hearing Loss ◽

Sensorineural Hearing Loss ◽

Cox Regression ◽

Sudden Sensorineural Hearing Loss ◽

Sensorineural Hearing ◽

Lower Percentage ◽

Research Database ◽

Patients With Diabetes

Background: The risk of sudden sensorineural hearing loss associated with metformin use in patients with diabetes mellitus has not been fully examined. Study design: It is a retrospective matched-cohort study. Subjects and methods: We examined the medical records of patients with diabetes mellitus over 18 years old in Taiwan’s National Health Insurance Research Database for the period between 1 January 2000 and 31 December 2013, to establish matched cohorts (14,109 with and 42,327 without metformin use) at a ratio of 1:3 by sex, age and index year. Results: We used a Cox regression hazard model to identify risk factors of sudden sensorineural hearing loss during 14 years of follow-up, and the results indicate that a significantly lower percentage of diabetes mellitus patients with metformin use ( p = 0.033) developed sudden sensorineural hearing loss compared with those without metformin use (0.21%, 29/14,109 vs 0.32%, 136/42,327). After adjustment for age and other variables [adjusted hazard ratio: 0.630 (95% confidence interval: 0.422–0.941, p = 0.024)], this study also demonstrated that metformin use appeared to reduce the risk of developing sudden sensorineural hearing loss. Conclusion: This study demonstrated an association between metformin use and lower incidence of sudden sensorineural hearing loss among patients with diabetes mellitus.

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To Study the Effect of Type II Diabetes Mellitus and Its Duration on Hearing

International Journal of Advanced and Integrated Medical Sciences ◽

10.5005/jp-journals-10050-10093 ◽

2017 ◽

Vol 2 (3) ◽

pp. 140-143

Author(s):

Sameer Aggarwal ◽

Vikas Kakkar ◽

Chandni Sharma ◽

Surender Bishnoi ◽

Ankit Gulati ◽

...

Keyword(s):

Diabetes Mellitus ◽

Hearing Loss ◽

Type Ii Diabetes ◽

Pure Tone Audiometry ◽

Type Ii Diabetes Mellitus ◽

Control Group ◽

Diabetic Patients ◽

Age Group ◽

Type Ii ◽

Group I

ABSTRACT Objective This study has been undertaken to study the effect of type II diabetes mellitus (T2DM) and its duration on hearing. Materials and methods The present study was conducted on 100 persons of age group 20 to 45 years. All subjects included in the study were divided into two groups. Group I: 50 patients suffering from T2DM (fasting blood sugar ≥ 126 mg/dL and postprandial ≥ 200 mg/dL) of either sex, in the age group of 20 to 45 years. Group II: 50 healthy volunteers in the age group of 20 to 45 years, of either sex were included in control group. Hearing assessment was done by using pure tone audiometry (PTA). Results In diabetic patients, the mean threshold in the PTA was higher at all frequencies as compared with healthy controls, and there was a positive correlation between the duration of diabetes and hearing loss. Conclusion Various audiological investigations have revealed that there is a strong association of diabetes with sensorineural part. The prevalence of sensorineural hearing loss (SNHL) in type II diabetics observed was 64%. In the majority of the patients, the hearing loss was bilateral, affecting mid and higher frequencies from 2 to 8 kHz. Hence, to conclude, we can say that the high prevalence of hearing loss in T2DM supports the importance of audiometric evaluation in such patients. How to cite this article Gulati A, Kakkar V, Aggarwal S, Sharma C, Panchal V, Pareek M, Bishnoi S. To Study the Effect of Type II Diabetes Mellitus and Its Duration on Hearing. Int J Adv Integ Med Sci 2017;2(3):140-143.

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Diabetes mellitus and sensorineural hearing loss: is there an association? Baseline of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil)

Clinics ◽

10.6061/clinics/2017(01)02 ◽

2017 ◽

Vol 72 (1) ◽

pp. 5-10 ◽

Cited By ~ 6

Author(s):

AG Samelli ◽

IS Santos ◽

RR Moreira ◽

CM Rabelo ◽

LP Rolim ◽

...

Keyword(s):

Diabetes Mellitus ◽

Hearing Loss ◽

Longitudinal Study ◽

Sensorineural Hearing Loss ◽

Sensorineural Hearing ◽

Adult Health

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Is type 1 diabetes mellitus a cause for subtle hearing loss in pediatric patients?

European Archives of Oto-Rhino-Laryngology ◽

10.1007/s00405-014-2994-6 ◽

2014 ◽

Vol 272 (8) ◽

pp. 1867-1871 ◽

Cited By ~ 9

Author(s):

Nader ALDajani ◽

Ahmad ALkurdi ◽

Angham ALMutair ◽

Abdullah ALdraiwesh ◽

Khalid A. ALMazrou

Keyword(s):

Diabetes Mellitus ◽

Type 1 Diabetes ◽

Hearing Loss ◽

Type 1 Diabetes Mellitus ◽

Pediatric Patients

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Hearing Loss in Patients with Diabetes Mellitus

Brazilian Journal of Otorhinolaryngology ◽

10.1016/s1808-8694(15)30498-5 ◽

2009 ◽

Vol 75 (4) ◽

pp. 573-578 ◽

Cited By ~ 2

Author(s):

Thiago Hernandes Diniz ◽

Heraldo Lorena Guida

Keyword(s):

Diabetes Mellitus ◽

Hearing Loss ◽

Patients With Diabetes

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AMBANG PENDENGARAN RATA–RATA PADA PENDERITA DIABETES MELITUS di POLIKLINIK ENDOKRINOLOGI RSUP PROF. Dr. R. D. KANDOU MANADO

e-CliniC ◽

10.35790/ecl.3.1.2015.6510 ◽

2015 ◽

Vol 3 (1) ◽

Author(s):

Febrina R. Wuwung ◽

Ora I. Palandeng ◽

Olivia C. P. Pelealu

Keyword(s):

Diabetes Mellitus ◽

Hearing Loss ◽

Pure Tone ◽

Hearing Threshold ◽

Pure Tone Audiometry ◽

The Body ◽

Cross Sectional ◽

Patients With Diabetes ◽

Cross Sectional Design ◽

Diabetes Melitus

Abstract: Diabetes mellitus is a group of chronic metabolic disease which can affect nearly every organ system in the body. Complications of this disease are diverse and include retinopathy, nepropathy and neuropathy. It has a high prevalence and continued to increase. The relationship between diabetes mellitus and hearing loss have been studied. This study aimed to obtain the average of hearing threshold in patients with diabetes mellitus. This was a descriptive observational study with a cross sectional design. Total 38 diabetes mellitus patients were included in the study. Hearing threshold obtained based on air conduction pure tone audiometry average at 500, 1000, 2000, and 4000 Hz. The results showed that subjects were 65.8% females and 32.4% males. There were 9 subjects (23.6%) with normal hearing, 24 subjects (63.2%) with bilateral hearing loss, and 5 subjects (13.2%) with unilateral hearing loss. Of the 29 subjects with hearing loss, the levels were mild and moderate. None of the subjects had moderately severe, severe, or profound. Conclusion: The majority of subjects in this study had hearing loss.Keywords: diabetes mellitus, hearing threshold, pure tone audiometryAbstrak: Diabetes melitus merupakan suatu kelompok penyakit metabolik kronik yang dapat mempengaruhi hampir setiap sistem organ dalam tubuh. Komplikasi penyakit ini beragam, termasuk retinopati, nefropati dan neuropati. Prevalensinya cukup tinggi dan diperkirakan akan terus meningkat. Terdapat beberapa penelitian yang menghubungkan diabetes melitus dan gangguan pendengaran. Penelitian ini bertujuan untuk mengetahui ambang pendengaran rata – rata pada penderita diabetes melitus. Penelitian ini merupakan penelitian deskriptif observasional dengan desain penelitian potong lintang. Sampel total ialah 38 pasien diabetes melitus. Ambang pendengaran rata – rata diperoleh berdasarkan hantaran udara audiometri nada murni rata-rata pada frekuensi 500, 1000, 2000, dan 4000 Hz. Hasil penelitian memperlihatkan bahwa subjek penelitian 65,8% perempuan dan 34,2% laki – laki. Terdapat 9 orang (23,6%) yang mempunyai pendengaran normal, 24 orang (63,2 %) mengalami gangguan pendengaran bilateral dan 5 orang (13,2%) dengan gangguan pendengaran unilateral. Dari 29 subjek penelitian dengan gangguan pendengaran mengalami gangguan pendengaran kategori ringan dan sedang. Tidak ditemukan subjek penelitian dengan gangguan pendengaran kategori sedang berat, berat atau sangat berat. Simpulan: Mayoritas subjek penelitian mengalami gangguan pendengar.Kata kunci: ambang pendengaran, audiometri nada murni, diabetes melitus

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