scholarly journals Analysis of Factors Affecting the Event of Diarrhea in Infants Age 0 to 2 Years

Author(s):  
Antika Maulida Rahayu ◽  
Ismarwati Ismarwati

Diarrhea is the number 2 cause of death among children under five in the world, number 3 in infants, and number 5 for all ages. There are several factors that influence the occurrence of diarrhea in infants apart from infectious factors (bacterial infections, viral infections, parasitic infections, parenteral infections). Other contributing factors are attainment of breastfeeding, food factors, and water sources used daily. The aim of this literature review is to analyze the factors that influence the incidence of diarrhea in infants aged 0 to 2 years. a process using the search stage to conduct a literature review. A search of relevant databases as well as literature and reference lists of included studies was carried out. An analysis of 10 journals conducted by researchers showed that infants aged 10 months who were fully breastfed when associated with diarrhea had lower scores (OR = 0.59, 95% CI 0.43-0.82), while children -children who received food and candy or milk were associated with an increased prevalence of diarrhea, namely (OR = 1.64, 95% CI 1.22-2.22 and OR = 1.67, 95% CI 1.21-2.30 ). And 2.58 times higher in homes with damaged water filters (OR = 2.58, 95% CI 0.1, 10.1) compared to homes with working water filters. 15% of families with good water filters reported diarrhea, while 31% of families with damaged water filters reported diarrhea. Exclusive breastfeeding for up to 6 months can reduce the risk of diarrhea in infants.

2015 ◽  
Vol 51 (2) ◽  
pp. 153-156
Author(s):  
Magdalena Bartold ◽  
Joanna Matowicka-Karna

Neopterin is a non-specific marker of immunological response of human body of cellular type. It belongs to the chemical group known as pteridines. Neopterin has been widely associated with inter alia viral infections, bacterial infections (by intracellular living bacteria), parasitic infections, skin burns or autoimmune diseases. Neopterin is a very important parameter diagnostically not only in diagnosis and monitoring of treatment but also a reliable indicator of macrophages’ activity. Most frequently neopterin concentration is measured in body fluids like blood, serum or urine, but it may be used as an indicator in other body fluids.


Author(s):  
NANDINI THUMMANAPALLY ◽  
KAVITHA LAWDYAVATH ◽  
CHARANDAS GURUVA ◽  
DEEPTHI ENUMULA ◽  
SASTRY PVK ◽  
...  

Objective: The objective of the study was to study the prevalence of various skin diseases in pediatric population. Methods: A prospective observational study was conducted at private children’s outpatient clinic in Warangal from March to August 2018 with the prior approval from the Institutional Ethical Committee BIPS/IEC/2018/P8. A total of 200 patients with various skin diseases of age group <17 years were included in the study. Results: Out of 200 pediatric skin disorders, male children 138 (69%) outnumbered female children 62 (31%). The mean age of the study population was found to be 5.85±4.11 years. About 64% of the patients are from rural area and 36% are from urban. The percentage of skin disorders is allergic infections (26%), bacterial infections (23%), viral infections (11%), fungal infections (7.5%), parasitic infections (6%), autoimmune disorders (4%), and skin adnexa (2.5%). Conclusion: Our study concludes that the prevalence of allergic and bacterial skin infections was found to be common among male children from rural area


2019 ◽  
Vol 65 (6) ◽  
pp. 816-824
Author(s):  
Darya Dubovichenko ◽  
Mikhail Valkov ◽  
Vakhtang Merabishvili ◽  
Anton Karpunov ◽  
Aleksandr Shcherbakov ◽  
...  

The article presents the epidemiological characteristics of rectal cancer (RC) over the world and in Russia, describes approaches to measuring the burden of the RC based on data from the scientific literature. It has been shown that the dynamics and levels of incidence and mortality in RC at the regional, national and global level should be assessed only on the basis population cancer registries data. The factors affecting the epidemiological indicators in the RC are described.


2021 ◽  
Vol 7 (Khusus) ◽  
pp. 12
Author(s):  
I Made Sudarta ◽  
Syafruddin Ali Salaka

The incidence of short toddlers commonly referred to as stunting is one of the nutritional problems worldwide. In 2017 22.2% or about 150.8 million toddlers in the world experienced stunting. The Integrated Toddler Nutrition Status Survey (SSGBI) by Balitbangkes Kemenkes Republik Indonesia in 2019 shows that the highest proportion of stunting is found in East Nusa Tenggara, West Sulawesi, and West Nusa Tenggara. The districts in West Sulawesi with the highest percentage of very short and short toddlers at the age of 0 – 59 months in 2018 were Mamuju Regency which is 20.08% and 26.38%. This study aims to determine the influence of protein and energy intake and exclusive breastfeeding history of breastfeeding on stunting events. This research is a literature review that summarizes some relevant literature. Articles searched using google scholar database. After the screening, 21 articles were eligible and met the criteria. There is an influence of protein and energy intake and exclusive breastfeeding on stunting. It is expected that the results of this study will become one of the educational materials and nursing interventions that can be applied in the health service in preventing stunting.


Author(s):  
Gavin P Spickett

Introduction Classification of secondary immunodeficiency Human immunodeficiency virus 1 and 2 Epstein–Barr virus Other viral infections Acute bacterial infections Chronic bacterial sepsis Bronchiectasis Fungal and parasitic infections Malignancy Myeloma Lymphoma: Hodgkin’s disease Non-Hodgkin’s lymphoma Chronic lymphocytic leukaemia (CLL) Chronic myeloid leukaemia (CML) and myelodysplastic syndromes...


2021 ◽  
Vol 22 (15) ◽  
pp. 8004
Author(s):  
Edna Ondari ◽  
Esther Calvino-Sanles ◽  
Nicholas J. First ◽  
Monica C. Gestal

Eosinophils are granulocytes primarily associated with TH2 responses to parasites or immune hyper-reactive states, such as asthma, allergies, or eosinophilic esophagitis. However, it does not make sense from an evolutionary standpoint to maintain a cell type that is only specific for parasitic infections and that otherwise is somehow harmful to the host. In recent years, there has been a shift in the perception of these cells. Eosinophils have recently been recognized as regulators of immune homeostasis and suppressors of over-reactive pro-inflammatory responses by secreting specific molecules that dampen the immune response. Their role during parasitic infections has been well investigated, and their versatility during immune responses to helminths includes antigen presentation as well as modulation of T cell responses. Although it is known that eosinophils can present antigens during viral infections, there are still many mechanistic aspects of the involvement of eosinophils during viral infections that remain to be elucidated. However, are eosinophils able to respond to bacterial infections? Recent literature indicates that Helicobacter pylori triggers TH2 responses mediated by eosinophils; this promotes anti-inflammatory responses that might be involved in the long-term persistent infection caused by this pathogen. Apparently and on the contrary, in the respiratory tract, eosinophils promote TH17 pro-inflammatory responses during Bordetella bronchiseptica infection, and they are, in fact, critical for early clearance of bacteria from the respiratory tract. However, eosinophils are also intertwined with microbiota, and up to now, it is not clear if microbiota regulates eosinophils or vice versa, or how this connection influences immune responses. In this review, we highlight the current knowledge of eosinophils as regulators of pro and anti-inflammatory responses in the context of both infection and naïve conditions. We propose questions and future directions that might open novel research avenues in the future.


BMC Medicine ◽  
2020 ◽  
Vol 18 (1) ◽  
Author(s):  
José Moreira ◽  
Janaina Barros ◽  
Oscar Lapouble ◽  
Marcus V. G. Lacerda ◽  
Ingrid Felger ◽  
...  

Abstract Background In malaria-endemic countries, febrile episodes caused by diseases other than malaria are a growing concern. However, limited knowledge of the prevalent etiologic agents and their geographic distributions restrict the ability of health services to address non-malarial morbidity and mortality through effective case management. Here, we review the etiology of fever in Latin America (LA) between 1980 and 2015 and map significant pathogens commonly implicated in febrile infectious diseases. Methods A literature search was conducted, without language restrictions, in three distinct databases in order to identify fever etiology studies that report laboratory-confirmed fever-causing pathogens that were isolated from usually sterile body sites. Data analyses and mapping was conducted with Tableau Desktop (version 2018.2.3). Results Inclusion criteria were met by 625 publications corresponding to data relative to 34 countries. Studies using serology (n = 339) predominated for viral infections, culture (n = 131) for bacteria, and microscopy (n = 62) for fungi and parasites. The pathogen groups most frequently reported were viral infections (n = 277), bacterial infections (n = 265), parasitic infections (n = 59), fungal infections (n = 47), and more than one pathogen group (n = 24). The most frequently reported virus was dengue virus (n = 171), followed by other arboviruses (n = 55), and hantavirus (n = 18). For bacteria, Staphylococcus spp. (n = 82), Rickettsia spp. (n = 70), and Leptospira spp. (n = 55) were frequently reported. Areas with biggest gaps on etiology of fever were apparent. Conclusions This review provides a landscape of pathogens causing febrile illness other than malaria in LA for over 30 years. Our findings highlight the need to standardize protocols and report guidelines for fever etiology studies for better comparability of results and improved interpretation. Lastly, we should improve existing national laboratory surveillance systems, especially from low- to middle-income countries, to inform global fever policy priorities and timely identify emerging infections threats. Study registration PROSPERO systematic review registration number: CRD42016049281


2020 ◽  
Vol 66 (1) ◽  
pp. 36-41
Author(s):  
Darya Dubovichenko ◽  
Mikhail Valkov ◽  
Vakhtang Merabishvili ◽  
Anton Karpunov ◽  
Aleksandr Shcherbakov ◽  
...  

The article presents the epidemiological characteristics of rectal cancer (RC) over the world and in Russia, describes approaches to measuring the burden of the RC based on data from the scientific literature. It has been shown that the dynamics and levels of RC survival at the regional, national and global level should be assessed only on the basis population cancer registries data. The factors affecting survival in the RC are described. Based on the published experience of organizing the diagnosis and treatment of RC in economically developed countries, measures are proposed for further improvement of survival in the RC in Russia.


Author(s):  
Ibrakhimova H.R. ◽  

The purpose of this study was to analyze the literary sources of recent years dedicated to the degree of occurrence, the structure of morbidity and the pathogenetic basis of parasitic infections occurring in children. In addition, the features of the detection of nematodes, cestodoses and rematodes in different countries of the world are given. The basics of diagnosis and prevention of parasitic infections in children are described.


BMC Medicine ◽  
2020 ◽  
Vol 18 (1) ◽  
Author(s):  
Jeanne Elven ◽  
Prabin Dahal ◽  
Elizabeth A. Ashley ◽  
Nigel V. Thomas ◽  
Poojan Shrestha ◽  
...  

Abstract Background The availability of reliable point-of-care tests for malaria has heralded a paradigm shift in the management of febrile illnesses away from presumptive antimalarial therapy. In the absence of a definitive diagnosis, health care providers are more likely to prescribe empirical antimicrobials to those who test negative for malaria. To improve management and guide further test development, better understanding is needed of the true causative agents and their geographic variability. Methods A systematic review of published literature was undertaken to characterise the spectrum of pathogens causing non-malaria febrile illness in Africa (1980–2015). Literature searches were conducted in English and French languages in six databases: MEDLINE, EMBASE, Global Health (CABI), WHO Global Health Library, PASCAL, and Bulletin de la Société Française de Parasitologie (BDSP). Selection criteria included reporting on an infection or infections with a confirmed diagnosis, defined as pathogens detected in or cultured from samples from normally sterile sites, or serological evidence of current or past infection. A number of published articles (rather than incidence or prevalence) reporting a given pathogen were presented. Results A total of 16,523 records from 48 African countries were screened, of which 1065 (6.4%) met selection criteria. Bacterial infections were reported in 564 (53.0%) records, viral infections in 374 (35.1%), parasitic infections in 47 (4.4%), fungal infections in nine (0.8%), and 71 (6.7%) publications reported more than one pathogen group. Age range of the study population was not specified in 233 (21.9%) publications. Staphylococcus aureus (18.2%), non-typhoidal Salmonella (17.3%), and Escherichia coli (15.4%) were the commonly reported bacterial infections whereas Rift Valley fever virus (7.4%), yellow fever virus (7.0%), and Ebola virus (6.7%) were the most commonly reported viral infections. Dengue virus infection, previously not thought to be widespread in Africa, was reported in 54 (5.1%) of articles. Conclusions This review summarises the published reports of non-malaria pathogens that may cause febrile illness in Africa. As the threat of antimicrobial resistance looms, knowledge of the distribution of infectious agents causing fever should facilitate priority setting in the development of new diagnostic tools and improved antimicrobial stewardship. Trial registration PROSPERO, CRD42016049281


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