SARS-CoV-2 on the move: Reviewing Innate vs Acquired for Covid-19
In this article we have put down certain facts reported so far and raised some pertinent questions to understand the progress of Covid-19 disease. We have discussed the important role of innate immunity to tame Covid-19. Basics of innate and adaptive immunity has been discussed for general audience. Subsequently, we have discussed why immunity fails leading to ‘immunity escape’. We have asked and tried to address few concerns such as: Can vaccines drive the pathogen to mutate to a higher virulent strain?; Evolution of more virulent pathogens; Evidence of new variants; Evidence of variants evading immunity; Antibody cocktail demand for new design of vaccine; Evidence of SARS-CoV-2 evades T cell responses; Imperfect leaky vaccine; Complete Mapping of Mutations to the SARS-CoV-2 Spike Receptor-Binding Domain; Where is the originally identified SARS-CoV-2 (labeled as D614) found first in Wuhan, China; Deletion of spike glycoprotein itself: How to fix missing?; What is the present status?; To be or not to be vaccinated?; The challenge of antigenic drift and antigenic shift; What causes variant and can it be controlled?; A new dawn in the fight against the disease, to be or not to be worried?; Judging the risk “risk management”; Prophylactic measures for covid 19: Changing Diet and life style; Maneuvering the pandemic and finally the “Take away message”.