scholarly journals Network Analysis of Physical and Psychiatric Symptoms of Hospital Discharged Patients Infected with COVID-19

2020 ◽  
Author(s):  
Dong Liu ◽  
Sacha Epskamp ◽  
Adela-Maria Isvoranu
Keyword(s):  
Directed Acyclic Graph ◽  
Psychiatric Symptoms ◽  
Demographic Characteristics ◽  
Causal Effects ◽  
Depression And Anxiety ◽  
Network Approach ◽  
Icu Admission ◽  
Discharged Patients ◽  
Graph Estimation ◽  
Anxiety Depression

In the current study, we aimed to investigate the network structure of COVID-19 symptoms and its related psychiatric symptoms, using a network approach. Specifically, we examined how COVID-19 symptoms relate to psychiatric symptoms and highlighted potential pathways between COVID-19 severity and psychiatric symptoms. With a sample of six hundred seventy-five recovered COVID-19 patients recruited 1 month after hospital discharge, we respectively integrated COVID-19 symptoms with PTSD, depression, and anxiety symptoms and analyzed the three network structures. In all three networks, COVID-19 severity and ICU admission are not linked directly to COVID-19 symptoms after hospitalization, while COVID-19 severity (but not ICU admission) is linked directly to one or more psychiatric symptoms. Specific pathways between COVID-19 symptoms and psychiatric symptoms were discussed. Finally, we used directed acyclic graph estimation to show potential causal effects between COVID-19 related variables and demographic characteristics. Keywords: COVID-19; symptom network; anxiety, depression, PTSD

Anxiety and Depression

2020 ◽  
pp. 158-179
Keyword(s):  
Anxiety Disorders ◽  
Autoimmune Thyroiditis ◽  
Psychiatric Symptoms ◽  
Early Recognition ◽  
Psychiatric Morbidity ◽  
Diagnostic Process ◽  
Depression And Anxiety ◽  
Depression Disorders ◽  
Anxiety Depression ◽  
Behavior And Cognition

It is an established entity that thyroid hormones play an important role in mood, behavior, and cognition. Autoimmune thyroiditis, including Hashimoto's thyroiditis (HT), can lead to depression and anxiety disorders. It is thus important to enhance awareness among physicians about this connection to accelerate the diagnostic process. In patients with depression and anxiety disorders, a test for autoimmune thyroiditis should be performed, and in patients with autoimmune thyroiditis, a screening for psychiatric symptoms is necessary. Thus, patients presenting with anxiety or depression disorders should be treated and monitored by both an endocrinologist and a psychiatrist in liaison with each other so as to optimize their management. Moreover, an early recognition of an endocrine condition will help minimize psychiatric morbidity and hence improve health. This chapter explores anxiety, depression, and Hashimoto's disease.

Family Environment and Its Correlation with Anxiety and Depression: A Study on Heart Patients

2016 ◽  
Vol 3 (2) ◽  
Author(s):  
Dr. Meena Jain ◽  
Saloni Chandalia
Keyword(s):  
Heart Disease ◽  
Family Environment ◽  
Heart Attack ◽  
Psychiatric Symptoms ◽  
Disease Risk ◽  
Positive Association ◽  
Anxiety And Depression ◽  
Depression And Anxiety ◽  
Increased Risk ◽  
Artery Disease

This research paper deals with the Family Environment and its Correlation with Anxiety and Depression level among persons with Heart Disease. There had been a number of researches that investigated that ischemic heart disease patients who suffer significant anxiety have close to a 5-fold increased risk of experiencing frequent angina and those with depression have more than a 3-fold increased risk for these episodes. This observed link between psychiatric symptoms and angina underlines the importance of treating anxiety and depression in cardiac patients, according to study co author Dr Mark D Sullivan (University of Washington School of Medicine, Seattle). To gather the needed data, Hamilton Anxiety Scale and Becks Depression Inventory were used. As stated from literatures, for people with heart dysfunction, depression and anxiety can increase the risk of an adverse cardiac event such as a heart attack or blood clots. For people who do not have heart disease, depression and anxiety can also increase the risk of a heart attack and development of coronary artery disease. Researchers have also emphasized on the role of family psychosocial environment and its positive association with the Coronary Heart Disease risk.

scholarly journals Impact of Depression and Anxiety on Dimensions of Health-Related Quality of Life in Subjects with Parkinson’s Disease Enrolled in an Association of Patients

2021 ◽  
Vol 11 (6) ◽  
pp. 771
Author(s):  
Fany Chuquilín-Arista ◽  
Tania Álvarez-Avellón ◽  
Manuel Menéndez-González
Keyword(s):  
Quality Of Life ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Psychiatric Symptoms ◽  
Well Being ◽  
Depression And Anxiety ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related

Parkinson’s disease (PD) is a complex disorder characterized by a wide spectrum of symptoms. Depression and anxiety are common manifestations in PD and may be determinants of health-related quality of life (HRQoL). The objective of this study is to determine the association of depression and anxiety with the dimensions of HRQoL in subjects with PD enrolled in an association of patients. Ninety-five community-based patients with PD diagnosis at different disease stages were studied. HRQoL was assessed using the Parkinson’s Disease Questionnaire (PDQ-39); depression and anxiety were assessed using the Beck Depression Inventory (BDI-II) and the State-Trait Anxiety Inventory (STAI), respectively. Our results showed that depression and anxiety were negatively associated with HRQoL measured by PDSI. Higher motor dysfunction measured by Hoehn and Yahr (H&Y) staging was also associated with worse HRQoL. Depression was the most influential variable in the model. All PDQ-39 dimensions except social support and bodily discomfort were associated with depression. Anxiety was associated with the emotional well-being and bodily discomfort dimensions. These results suggest that physicians should pay attention to the presence of psychiatric symptoms and treat them appropriately.

scholarly journals Network Analysis of Physical and Psychiatric Symptoms of Hospital Discharged Patients Infected with COVID-19

2021 ◽  
Author(s):  
Dong Liu ◽  
Sacha Epskamp ◽  
Adela-Maria Isvoranu ◽  
Caixia Chen ◽  
Wenjun Liu ◽  
...  
Keyword(s):  
Network Analysis ◽  
Psychiatric Symptoms ◽  
Discharged Patients

Frontotemporal dementia and financial capacity: facing the Cerberus of overestimation or underestimation?

2021 ◽  
pp. 103985622110054
Author(s):  
Vaitsa Giannouli ◽  
Magda Tsolaki
Keyword(s):  
Financial Performance ◽  
Frontotemporal Dementia ◽  
Objective Assessment ◽  
Third Party ◽  
Clinical Settings ◽  
Depression And Anxiety ◽  
Financial Capacity ◽  
Gender Education ◽  
Visuospatial Skills ◽  
Anxiety Depression

Objective: This study investigates the performance of people with frontotemporal dementia (FTD) on objective assessment of financial capacity with comparison to the estimation of financial capacity by both people themselves and their caregivers. Method: FTD patients and healthy (age/gender/education-matched) controls from Greece underwent cognitive assessment (memory, attention, executive functioning, visuospatial skills, verbal functions), emotional (anxiety, depression), and financial capacity assessment (Legal Capacity for Property Law Transactions Assessment Scale—LCPLTAS). Additionally, they self-reported on their financial performance and a third-party living with the older participants for both groups reported their estimates of financial performance and their anxiety and depression levels. Results: Financial capacity in FTD patients is severely impaired compared to controls, but caregivers of FTD patients tend to overestimate the patients’ financial performance, a finding that is not related to the caregivers’ depression and anxiety levels or other demographics. FTD patients overestimate their financial capacity. Conclusion: FTD may have significant impact on financial capacity, but people with FTD tend to overestimate their own financial capacity. This study also indicates that families and caregivers tend to overestimate financial capacity in people with FTD. This has implications for the assessment and care planning of people with FTD in clinical settings.

scholarly journals Adverse health behaviours are associated with depression and anxiety in multiple sclerosis: A prospective multisite study

2015 ◽  
Vol 22 (5) ◽  
pp. 685-693 ◽  
Author(s):  
Kyla A. McKay ◽  
Helen Tremlett ◽  
John D. Fisk ◽  
Scott B. Patten ◽  
Kirsten Fiest ◽  
...  
Keyword(s):  
Mental Health ◽  
Multiple Sclerosis ◽  
Alcohol Dependence ◽  
Smoking Status ◽  
Health Behaviours ◽  
Depression And Anxiety ◽  
Adverse Health ◽  
Disability Status ◽  
Relapsing Remitting ◽  
Anxiety Depression

Background: Depression and anxiety are common among people with multiple sclerosis (MS), as are adverse health behaviours, but the associations between these factors are unclear. Objective: To evaluate the associations between cigarette smoking, alcohol use, and depression and anxiety in MS in a cross-Canada prospective study. Methods: From July 2010 to March 2011 we recruited consecutive MS patients from four MS clinics. At three visits over two years, clinical and demographic information was collected, and participants completed questionnaires regarding health behaviours and mental health. Results: Of 949 participants, 75.2% were women, with a mean age of 48.6 years; most had a relapsing−remitting course (72.4%). Alcohol dependence was associated with increased odds of anxiety (OR: 1.84; 95% CI: 1.32–2.58) and depression (OR: 1.53; 95% CI: 1.05–2.23) adjusting for age, sex, Expanded Disability Status Scale (EDSS), and smoking status. Smoking was associated with increased odds of anxiety (OR: 1.29; 95% CI: 1.02–1.63) and depression (OR: 1.37; 95% CI: 1.04–1.78) adjusting for age, sex, EDSS, and alcohol dependence. Alcohol dependence was associated with an increased incidence of depression but not anxiety. Depression was associated with an increased incidence of alcohol dependence. Conclusion: Alcohol dependence and smoking were associated with anxiety and depression. Awareness of the effects of adverse health behaviours on mental health in MS might help target counselling and support for those ‘at risk’.

Prospective Trial of L-tryptophan in Maternity Blues

1980 ◽  
Vol 137 (3) ◽  
pp. 233-235 ◽  
Author(s):  
Brian Harris
Keyword(s):  
Psychiatric Symptoms ◽  
Prospective Trial ◽  
Bottle Feeding ◽  
Double Blind ◽  
Middlesex Hospital ◽  
Multiparous Women ◽  
Anxiety Depression

SummaryUnder double blind conditions 55 young, bottle feeding, multiparous women received L-tryptophan 3 g daily or placebo for ten days after delivery, and were also assessed daily for psychiatric symptoms. This treatment did not reduce ‘maternity blues', but the mothers' blues scores correlated significantly with the scores for anxiety, depression and hysteria on the Middlesex Hospital Questionnaire given in the eighth month of pregnancy.

scholarly journals Effectivity of Psychotherapy Interventions for Anxiety in Medical Students: A Systematic Review

2021 ◽  
Vol 9 (F) ◽  
pp. 453-463
Author(s):  
Andrian Fajar Kusumadewi ◽  
Carla Raymondalexas Marchira ◽  
Widyandana Widyandana ◽  
Ronny Tri Wirasto
Keyword(s):  
Systematic Review ◽  
Medical Students ◽  
Systematic Reviews ◽  
Depression And Anxiety ◽  
Inclusion Criteria ◽  
Meta Analyses ◽  
And Behavior ◽  
Anxiety Depression ◽  
Suicidal Ideas ◽  
Psychotherapy Interventions

BACKGROUND: The mental health of medical students has long been a topic of concern in many countries. Much research in Europe reported that around 30% of medical students suffered from anxiety. Anxiety disorders have significant physical and emotional consequences. Various studies show that excessive, unmanaged stress related to poor academic performance in medical students leads to cynical personalities, lack of empathy, and suicidal ideas. AIM: This study aimed to identify studies for psychotherapy interventions carried out in medical students and analyze each impact on anxiety level in medical students. METHODS: This systematic review was conducted with evidence sourced from 2000 to 2020. The review process followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. The study was registered with the Prospective Registering of Systematic Reviews database (Protocol ID: CRD42020180650). RESULTS: Twenty-three studies meet the inclusion criteria, and there are various psychotherapy interventions to deal with anxiety. Most studies reported that students who received mindfulness-based interventions reported lower anxiety, depression, and stress. CONCLUSION: There are various interventions carried out to decrease stress levels, depression, and anxiety in medical students. The most effective psychotherapy was found in cognitive and behavior intervention and mindfulness intervention.

scholarly journals Cytokeratin 18 cell death assays as biomarkers for quantification of apoptosis and necrosis in COVID-19: a prospective, observational study

2021 ◽  
pp. jclinpath-2020-207242
Author(s):  
Brandon Michael Henry ◽  
Isaac Cheruiyot ◽  
Stefanie W Benoit ◽  
Fabian Sanchis-Gomar ◽  
Giuseppe Lippi ◽  
...  
Keyword(s):  
Cell Death ◽  
Cell Damage ◽  
Severe Disease ◽  
Total Cell ◽  
Cytokeratin 18 ◽  
Icu Admission ◽  
Main Driver ◽  
Discharged Patients ◽  
Apoptosis And Necrosis ◽  
Epithelial Cell Death

BackgroundThe mechanism by which SARS-CoV-2 triggers cell damage and necrosis are yet to be fully elucidated. We sought to quantify epithelial cell death in patients with COVID-19, with an estimation of relative contributions of apoptosis and necrosis.MethodsBlood samples were collected prospectively from adult patients presenting to the emergency department. Circulating levels of caspase-cleaved (apoptosis) and total cytokeratin 18 (CK-18) (total cell death) were determined using M30 and M65 enzyme assays, respectively. Intact CK-18 (necrosis) was estimated by subtracting M30 levels from M65.ResultsA total of 52 COVID-19 patients and 27 matched sick controls (with respiratory symptoms not due to COVID-19) were enrolled. Compared with sick controls, COVID-19 patients had higher levels of M65 (p = 0.046, total cell death) and M30 (p = 0.0079, apoptosis). Hospitalised COVID-19 patients had higher levels of M65 (p= 0.014) and intact CK-18 (p= 0.004, necrosis) than discharged patients. Intensive care unit (ICU)-admitted COVID-19 patients had higher levels of M65 (p= 0.004), M30 (p= 0.004) and intact CK-18 (p= 0.033) than hospitalised non-ICU admitted patients. In multivariable logistic regression, elevated levels of M65, M30 and intact CK-18 were associated with increased odds of ICU admission (OR=22.05, p=0.014, OR=19.71, p=0.012 and OR=14.12, p=0.016, respectively).ConclusionNecrosis appears to be the main driver of hospitalisation, whereas apoptosis and necrosis appear to drive ICU admission. Elevated levels CK-18 levels are independent predictors of severe disease, and could be useful for risk stratification of COVID-19 patients and in assessment of therapeutic efficacy in early-phase COVID-19 clinical trials.

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