scholarly journals Effect of immune-modulators (Rasayana Dravya) in Janapadodhwansa WSR to COVID-19

2020 ◽  
Vol 6 (1) ◽  
pp. 26-29
Author(s):  
Vaidya Pratigya Chauhan ◽  
◽  
Bhawna Dutt ◽  
Mahesh Vyas ◽  
S. K. Gupta ◽  
...  
Keyword(s):  
Health Care ◽  
Immune Response ◽  
21St Century ◽  
Preventive Measures ◽  
Experimental Studies ◽  
Collective Actions ◽  
Immune Modulators ◽  
Ancient Science ◽  
The People

Ayurveda provide a basic way of living to the people and mentioned the different “Charyas” to be done by the individuals in day to day life as well as this ancient science garlanded us with the knowledge and code of conducts to conduct different type of studies like experimental studies, survey studies etc. In this sequence, Janapadodhwansa, a chapter describes in Vimana Sthana by Acharya Charaka is considered as the chapter of epidemiological study. Where he explained the whole concept on handling the situation of pandemic state. Now, a days It is evident to notify the Pandemic state of China and different countries due to the virus knows as corona virus, which is responsible and causes pressure on societies and health care system. This is the first pandemic condition of 21st century which requires internationally unified cogent and collective actions by the individuals, communities, commercial bodies etc. Due to the novelty of the virus, there is no treatment known and no vaccination is available. Only social distancing and other preventive measures are tolls used to deal this emergency. And hence, this condition can be correlated with Janapadodhwansa. And Rasayana is one of them, which provide the strength against the viral condition and improve the immune response towards this pandemic disease. This article aims to provide information about role of Rasayana dravyas (Gudhuchi, Amalaki and Haridra) which can be in cooperated in day to day life and act as immune modulators.

Covid-19 – rumours and facts in media

2020 ◽  
Vol 11 (SPL1) ◽  
pp. 171-174
Author(s):  
Tarare Toshida ◽  
Chaple Jagruti
Keyword(s):  
Social Media ◽  
Preventive Measures ◽  
Vital Role ◽  
The Other ◽  
Sources Of Information ◽  
Other Hand ◽  
Corona Virus ◽  
The People ◽  
The World

The covid-19 resulted in broad range of spread throughout the world in which India has also became a prey of it and in this situation the means of media is extensively inϑluencing the mentality of the people. Media always played a role of loop between society and sources of information. In this epidemic also media is playing a vital role in shaping the reaction in ϑirst place for both good and ill by providing important facts regarding symptoms of Corona virus, preventive measures against the virus and also how to deal with any suspect of disease to overcome covid-19. On the other hand, there are endless people who spread endless rumours overs social media and are adversely affecting life of people but we always count on media because they provide us with valuable answers to our questions, facts and everything in need. Media always remains on top of the line when it comes to stop the out spread of rumours which are surely dangerous kind of information for society. So on our side we should react fairly and maturely to handle the situation to keep it in the favour of humanity and help government not only to ϑight this pandemic but also the info emic.

scholarly journals The Role of Developmental Networks in Building a Managerial Career

2020 ◽  
pp. 089484531990028
Author(s):  
Marianne Ekonen ◽  
Pia Heilmann
Keyword(s):  
21St Century ◽  
Male And Female ◽  
Developmental Networks ◽  
The People

The purpose of this study is to examine the role of developmental networks in a managerial career. We argue that the 21st-century managerial career is constructed in interaction with developmental networks. The people around one and the prevailing situation can either promote or restrict a person’s career. We search for answers to the questions of (1) what kinds of developmental networks exist and (2) how developmental networks affect managerial careers. We interviewed 16 managers, both male and female, in semistructured thematic interviews. We discovered six core narratives of developmental networks: enticers, recognizers, supporters, challengers, blockers, and demotivators. Our results highlight the importance of support and developmental networks in managerial careers.

scholarly journals Overlooked and undervalued: the caring contribution of older people

2014 ◽  
Vol 41 (5) ◽  
pp. 397-419 ◽  
Author(s):  
Fiona Carmichael ◽  
Marco G. Ercolani
Keyword(s):  
Health Care ◽  
Older People ◽  
Personal Care ◽  
Data Set ◽  
Content Type ◽  
The People ◽  
Ordered Logistic Regression ◽  
Allocation Of Time ◽  
Nationally Representative

Purpose – Older people are often perceived to be a drain on health care resources. This ignores their caring contribution to the health care sector. The purpose of this paper is to address this imbalance and highlight the role of older people as carers. Design/methodology/approach – The study uses a unique data set supplied by a charity. It covers 1,985 caregivers, their characteristics, type and amount of care provided and the characteristics and needs of those cared-for. Binary and ordered logistic regression is used to examine determinates of the supply of care. Fairlie-Oaxaca-Blinder decompositions are used to disentangle the extent to which differences in the supply of care by age are due to observable endowment effects or coefficient effects. Nationally representative British Household Panel Survey data provide contextualization. Findings – Older caregivers are more intensive carers, caring for longer hours, providing more co-residential and personal care. They are therefore more likely to be in greater need of assistance. The decompositions show that their more intensive caring contribution is partly explained by the largely exogenous characteristics and needs of the people they care for. Research limitations/implications – The data are regional and constrained by the supplier's design. Social implications – Older carers make a significant contribution to health care provision. Their allocation of time to caregiving is not a free choice, it is constrained by the needs of those cared-for. Originality/value – If the burden of care and caring contribution are measured by hours supplied and provision of intimate personal care, then a case is made that older carers experience the greatest burden and contribute the most to the community.

scholarly journals Role of Plasma Membrane Redox Activities in Immune Response Mechanisms

2021 ◽  
Vol 9 (12) ◽  
pp. 120-125
Author(s):  
Neerja Masih
Keyword(s):  
Oxidative Stress ◽  
Immune Response ◽  
Plasma Membrane ◽  
Redox System ◽  
Cell Immune Response ◽  
Immune Modulators ◽  
Plasma Membrane Redox ◽  
Redox Molecules ◽  
Flavin Binding

Abstract: The plasma membrane redox system (PMRS) is an important component of the cell's ability to defend itself against oxidative stress. Many immune signaling pathways are regulated through redox reactions. Biological systems utilize oxidationreduction reactions to modulate their responses to environmental cues. The role of redox molecules such as NO and ROS as key mediators of immunity has recently gathered a lot of interest and attention. Beyond the chemical interactions of NO and ROS that combine to eradicate pathogens, these redox small molecules are effective immune-modulators that regulate cellular metabolism as well as multiple pro-inflammatory and repair/tissue-restoration pathways. Redox molecules such as peroxide, superoxide, NO, and RNS, once thought to be only toxic, are essential in tissue repair. These species are generated, converted and metabolized during host microbe interaction involving the innate immune system. Cytochrome b558 is the flavin binding component of the NADPH oxidase. NADPH oxidases are key producers of ROS. A variety of RNS and ROS is produced in the acidic mileu of phagosomes, which provide an environment conducive to the redox chemistry, which is the first line in fighting infection. Bacterial cell immune response also involves NO. Thus understanding the plasma membrane redox activities can help unravel the mechanisms of immune response. Keywords: Plasma membrane, Redox activities, oxidative stress, NO, ROS, RNS. Nitrous Oxide, Reactive Oxygen Species, Reactive Nitrogen species.

scholarly journals Immunity Boosting Drugs in Ayurveda – A Review

2020 ◽  
Vol 11 (SPL4) ◽  
pp. 992-996
Author(s):  
Prasad Umakant Wallalwar ◽  
Pradnya Dandekar ◽  
Shweta Dadarao Parwe
Keyword(s):  
Immune System ◽  
Medical Science ◽  
Experimental Studies ◽  
Healthy Person ◽  
Review Article ◽  
Medicinal Herbs ◽  
Immune Modulators ◽  
Diseased Condition ◽  
Immense Potential

The concept of Immunity is mentioned as ‘Vyadhikshamatwa’ in Ayurveda. In Ayurveda numbers of medicinal herbs are described under immunity-enhancing drugs category. The concept of immunity enhancer is explained under the category of Rasayan chikitsa in Ayurveda. These herbs are used in various diseases, especially by modulating the immune system. These herbs are called as Rasayan Dravyas. Ayurveda medical science comprises the herbs which are Rasayana and also which are non-Rasayana in nature. In Samhitas entirely enriched with enormous data of Rasayana medicinal herbs acting as immune modulators. The data of available Samhitas and researches show that these Rasayana herbs have immense potential as immune modulators. Advanced researches have proven that drugs like Guduchi, Haritaki, Ashwagandha, Brahmi, Jyotishmati act as a good immune enhancer. Theses herbs are mentioned in Ayurveda as Rasayana drugs. Experimental studies also have proven the role of Rasayana drugs as antioxidant, adoptogenic and having anti-stress activities. These Rasayana drugs as having immunity enhancer protect the health of a healthy person and protects them from any type of diseased condition. Charakacharya had mentioned Rasayanchikitsa adhyay as the first addhya of their chikitsasthan considering his aim as ‘Swasthasya Swasthya Rakshanam’. This means to protect the health of a healthy person as in priority by using immunity enhancer drugs as Rasayanas. This review article empowers such reviewed data on Rasayan medicinal herbs as a promising future target for immunotherapy.

scholarly journals Comprehensive literature review on COVID-19 vaccines and role of SARS-CoV-2 variants in the pandemic

2021 ◽  
Vol 9 ◽  
pp. 251513552110597
Author(s):  
Charles Yap ◽  
Abulhassan Ali ◽  
Amogh Prabhakar ◽  
Akul Prabhakar ◽  
Aman Pal ◽  
...  
Keyword(s):  
Immune Response ◽  
Literature Review ◽  
Preventive Measures ◽  
Rapid Expansion ◽  
Personal Hygiene ◽  
The Novel ◽  
Vaccine Research ◽  
Hygiene Measures ◽  
Dosing Strategies

Since the outbreak of the COVID-19 pandemic, there has been a rapid expansion in vaccine research focusing on exploiting the novel discoveries on the pathophysiology, genomics, and molecular biology of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Although the current preventive measures are primarily socially distancing by maintaining a 1 m distance, it is supplemented using facial masks and other personal hygiene measures. However, the induction of vaccines as primary prevention is crucial to eradicating the disease to attempt restoration to normalcy. This literature review aims to describe the physiology of the vaccines and how the spike protein is used as a target to elicit an antibody-dependent immune response in humans. Furthermore, the overview, dosing strategies, efficacy, and side effects will be discussed for the notable vaccines: BioNTech/Pfizer, Moderna, AstraZeneca, Janssen, Gamaleya, and SinoVac. In addition, the development of other prominent COVID-19 vaccines will be highlighted alongside the sustainability of the vaccine-mediated immune response and current contraindications. As the research is rapidly expanding, we have looked at the association between pregnancy and COVID-19 vaccinations, in addition to the current reviews on the mixing of vaccines. Finally, the prominent emerging variants of concern are described, and the efficacy of the notable vaccines toward these variants has been summarized.

scholarly journals Atendimento de gestantes na atenção primária a saúde pela enfermagem durante a pandemia do SARS-COV-2

2020 ◽  
Vol 23 (269) ◽  
pp. 4723-4730
Author(s):  
Mirelly Shatilla Misquita ◽  
Patricia Gomes da Silva ◽  
Geovana De Abreu Braz ◽  
Anna Beatriz De Almeida Gomes Sousa ◽  
Dilene Fontele Catunda Melo ◽  
...  
Keyword(s):  
Health Care ◽  
Health Education ◽  
Prenatal Care ◽  
Patient Care ◽  
Pregnant Women ◽  
Preventive Measures ◽  
Descriptive Study ◽  
Easy Access ◽  
Nursing Professional

Objective: Describe the role of nurses in carrying out prenatal consultations during the pandemic within the scope of Primary the Health Care. Method: Descriptive study, an experience report. The same occurred in the period from March 2020 until June 2020 in the micro-region of the Sertões de Crateús, Ceara. Results: The nursing professional plays an important role in guiding the entire population, especially pregnant women, who are at risk and are still attending the unit with certain frequency. Under this bias, health education in times of pandemic has focused on preventive measures against the SARS-Cov-2 virus. Conclusion: In this way, the strategy used qualifies as a useful instrument with easy access and that generates impacts on the population. Enabling a continuous intervention in patient care, with regard to prenatal care, the spread of knowledge, acts in a way to promote health and prevent injuries.

scholarly journals Towards a People’s Social Epidemiology: Envisioning a More Inclusive and Equitable Future for Social Epi Research and Practice in the 21st Century

2019 ◽  
Vol 16 (20) ◽  
pp. 3983 ◽  
Author(s):  
Ryan Petteway ◽  
Mahasin Mujahid ◽  
Amani Allen ◽  
Rachel Morello-Frosch
Keyword(s):  
21St Century ◽  
Social Inclusion ◽  
Social Epidemiology ◽  
Community Based Participatory Research ◽  
Environmental Research ◽  
The People ◽  
Information And Communication ◽  
Ict Tools ◽  
Technological Affordances

Social epidemiology has made critical contributions to understanding population health. However, translation of social epidemiology science into action remains a challenge, raising concerns about the impacts of the field beyond academia. With so much focus on issues related to social position, discrimination, racism, power, and privilege, there has been surprisingly little deliberation about the extent and value of social inclusion and equity within the field itself. Indeed, the challenge of translation/action might be more readily met through re-envisioning the role of the people within the research/practice enterprise—reimagining what “social” could, or even should, mean for the future of the field. A potential path forward rests at the nexus of social epidemiology, community-based participatory research (CBPR), and information and communication technology (ICT). Here, we draw from social epidemiology, CBPR, and ICT literatures to introduce A People’s Social Epi—a multi-tiered framework for guiding social epidemiology in becoming more inclusive, equitable, and actionable for 21st century practice. In presenting this framework, we suggest the value of taking participatory, collaborative approaches anchored in CBPR and ICT principles and technological affordances—especially within the context of place-based and environmental research. We believe that such approaches present opportunities to create a social epidemiology that is of, with, and by the people—not simply about them. In this spirit, we suggest 10 ICT tools to “socialize” social epidemiology and outline 10 ways to move towards A People’s Social Epi in practice.

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