scholarly journals COVID like illness versus COVID-19 (CLIC STUDY) – Clinical profile and outcome

2022 ◽  
Vol 13 (1) ◽  
pp. 8-12
Author(s):  
Jeetendra Kumar J Mood ◽  
Avinash H Rajanna ◽  
Vaibhav S Bellary ◽  
Gowtham S Gowda ◽  
Yamini Marimuthu

Background: In December 2019, several cases of acute respiratory illness were detected in Wuhan city of China. This SARS-CoV-2 has been rapidly spreading worldwide ever since. SARS-CoV-2 has the potential to damage the vital organs such as lung, heart, liver, and kidney, and infection poses a considerable risk to patients by the high prevalence of pneumonia. Aims and Objectives: The objectives of the study are as follows: (1) To study clinical profile and biochemical markers in SARI patients. (2) To compare the clinical profile and biochemical markers between SARS-CoV-2 positive and negative patients and their outcomes. Materials and Methods: The present study is a hospital-based prospective cross-sectional study conducted on a total of 350 patients (150 SARI+200 COVID-19) in Bengaluru during the study period from June 2020 to May 2021. Results: Diabetes mellitus was present in 30% of SARI and 42% in COVID-19 patients (P=0.03). Leukocytosis (Total Leukocyte Count [TLC] >11000 cells/mm3) was more common among SARI patients than COVID-19 patients (49.3% vs. 24.3%). Leukopenia (TLC <4000 cells/mm3) was significantly more common in COVID-19 patients than in SARI patients (10.2% vs. 3.6%, P<0.001). Conclusion: COVID-19 infection is more common in patients with comorbidities such as diabetes mellitus and hypertension than SARI. Leukopenia was more common in COVID-19 patients whereas leukocytosis was more common in SARI patients.

2019 ◽  
Vol 26 (06) ◽  
Author(s):  
Abid Naeem ◽  
Muhammad Shuaib ◽  
Subtain-Ul- Hassan Abid ◽  
Muhammad Huzaifa Abid ◽  
Muhammad Imran

Introduction: Diabetes is a very prevalent problem in Pakistan. Depression along with diabetes affects not only quality of life but compliance and management of patient. Various studies have found high prevalence of depression among T2DM depression. In our study we shall determine the prevalence of depression among T2DM patients in Pakistan. Period: May 2017 to December 2017. Objectives: The objective of this study was to find out the prevalence of depression in Type2 diabetes mellitus patients. Study Design: A cross-sectional study. Setting: Jinnah Post Graduate Medical Centre Karachi. Results: Mean PHQ- Score is 10.83±5.6. 81.9% had PHQ Score > 4. According to PHQ-9 scale, 18.1% (n=30) had no depression, 26.5% (n=44) had moderately severe depression and 3.6% (n=6) had severe depression. In our study females had more severe depression in comparison with male (5.2% vs. 0%). Conclusion: Depression is very common in Pakistan among Type 2 Diabetic patients. Antidepressant has key role to break the vicious cycle of depression and type2 diabetes mellitus diabetes.


Author(s):  
Michael A. Olamoyegun ◽  
Oluwabukola A. Ala ◽  
Emmanuel Y. Fagbemiro

Background: Sexual dysfunction of which erectile dysfunction is one of the complications usually occurred in men with diabetes mellitus. Hence this study aimed to assess the prevalence and analyze risk factors for erectile dysfunction (ED) in patients with type 2 diabetes mellitus (DM). Materials and Methods: This is a cross-sectional study of 147 men with type 2 DM recruited from the diabetes clinic of a tertiary health institution in Nigeria. ED was assessed using an abridged version of international index of erectile function (IIEF–5). Sociodemographic data that included age, education, occupation, marital status were assessed and medical history including diabetes duration, smoking, alcohol intake, frequency and style of sexual intercourse obtained. Results: The mean age of the study sample was 68.22±12.15 years. The prevalence of ED was 69.5%, of which 14.3%, 14.3%, 10.5% and 29.9% had mild, mild-moderate, moderate and severe dysfunctions respectively. The prevalence of ED increased with age, duration of diabetes and obesity but not with glycaemic control, consumption of alcohol or smoking. Conclusions: ED was highly prevalent among men with DM in South-West Nigeria. Hence, efforts must be made to reduce the high prevalence by managing the factors responsible for its development. Also, health care practitioners must regularly inquire about this specifically as patients may not readily volunteer this information.


2018 ◽  
Vol 5 (1) ◽  
pp. 115
Author(s):  
Rajesh Kumar Khare ◽  
Vivek Katiyar

Background: The burden of diabetes mellitus is increasing worldwide. The prevalence of TB has been rising in recent years globally. Aging, changes in life style, socioeconomic factors, and population growth have lead to an increased prevalence of DM, particularly, type 2 DM. Diabetes Mellitus (DM) almost triples the risk of developing tuberculosis (TB). India, the nation with the highest number of TB cases in the world, is also undergoing epidemic growth in DM rates. With the demographic transition underway globally, increase in life expectancy, improvements in provision of health services and a subsequent increase in the elderly population, the absolute numbers of cases of diabetes will increase exponentially. As a result, DM and TB are increasingly present together, and this calls for renewed interest in this topic. Various studies done in different parts of India and in other parts of globe where TB is endemic have shown a higher prevalence of DM among PT infected with tuberculosis. We in our study undertaken in Department of medicine in IIMS&R Lucknow UP found a high prevalence of DM amongst TB patients. Routine screening of TB patients for DM will help detect cases of diabetes and pre-diabetes early, so that primary prevention methods may be initiated early and effectively.Methods: This hospital-based cross-sectional study was undertaken in Department of medicine in IIMS and R Lucknow UP. All TB cases more than 18 years of age, including new and re-treatment cases, sputum positive, sputum negative and extra-pulmonary cases currently on treatment in the were included in the study.Results: Using the diagnostic criteria, as mentioned in the methodology, the prevalence of diabetes among TB patients in this study was found to be 24.5% of which 18.5% were known DM cases and 5.9% were newly diagnosed.Conclusions: The burden of diabetes mellitus is increasing worldwide. The association between diabetes and tuberculosis is the next challenge for global tuberculosis control. Improved understanding of the bidirectional relationship of the two diseases is necessary for proper planning and collaboration to reduce the dual burden of diabetes and TB. In people with TB, it may be appropriate to actively screen for DM. Prevention, screening, and treatment of both diseases together is more effective.  


2021 ◽  
Vol 10 (1) ◽  
pp. 29-32
Author(s):  
Sanjay Shrestha ◽  
Rajesh Kumar Mandal ◽  
Kijan Maharjan

Background and Aims: Microalbuminuria is an early marker of diabetic nephropathy, which accounts for a significant reduction in life expectancy of diabetic patients. Timely detection of microalbuminuria facilitates appropriate preventive and therapeutic approaches to minimize risks. The aim of this study is to determine the prevalence and association of microalbuminuria with clinical profile and complications of type 2 diabetes mellitus. Methods: This study was a descriptive, cross sectional study involving 100 diabetic subjects between July 2018 to January 2019 at Bir Hospital. Microalbuminuria (mg/dl) was defined as spot urine albumin to creatinine ratio of 30-300 mg/g (Kidney Disease Improving Global Outcomes guidelines) in a single spot urine sample. Statistical analysis was done using Statistical package for the social sciences version 20. Results: Microalbuminuria was found in 35% of the sample and the rate was significantly higher among males (P =0.027). Microalbuminuria was significantly related to Body mass index (P = 0.018), duration of diabetes (P =0.000), retinopathy (P = 0.000) and stroke (P = 0.043). No statistically significant relation was found between microalbuminuria and age (P = 0.366), hypertension (P = 0.208), HbA1c (P = 0.098), dyslipidemia (P = 0.171) and ischemic heart disease (P = 0.651). Conclusions: This study shows high prevalence of microalbuminuria in Nepalese Type 2 diabetes mellitus. Screening for microalbuminuria should be done for all the type 2 diabetes mellitus patients for early detection and management of complications of diabetes mellitus.  


2018 ◽  
Vol 08 (02) ◽  
pp. 114-116
Author(s):  
Muhammad Shahrukh Khan Sadiq ◽  
Moona Mumtaz ◽  
Syed Abrar Ali ◽  
Jouhrah Hussain Khan ◽  
Syed Ahmed Omer ◽  
...  

Objective: Oral pathological findings are often associated with diabetes mellitus. The aim of the study was to assess the frequency of oral findings among diabetic patients of both genders. Materials and Methods: A cross-sectional observational study was conducted from February 2017 to November 2017 at Bahria University Dental Hospital & Mamji Hospital, Karachi. A total of 363 diagnosed patients of diabetes mellitus were selected for the study. A questionnaire was designed and oral clinical examination was performed. The collected data was analyzed by using SPSS version 23. Results: A total number of 363 diagnosed patients of diabetes mellitus were included in the study. Among these 187 (51.52%) were male and 176 (48.48%) were female. The overall oral mucosal findings were predominantly present in male diabetic patients as compared to females. Conclusion: The result of this study showed a high prevalence of oral pathological findings in diabetic patients


2021 ◽  
Vol 42 ◽  
Author(s):  
Aline Ale Beraldo ◽  
Rubia Laine de Paula Andrade ◽  
Érika Simone Galvão Pinto ◽  
Reinaldo Antônio da Silva-Sobrinho ◽  
Nanci Michele Saita ◽  
...  

ABSTRACT Objective To analyze the sociodemographic and clinical profile of tuberculosis cases with Diabetes Mellitus in Brazilian municipalities in the states of São Paulo, Paraná and Rio Grande do Norte. Method This is a cross-sectional study, whose population consisted of tuberculosis cases notified between 2010 and 2014. Data were collected from secondary sources. In the data analysis, descriptive analysis and multiple correspondence analysis techniques were used. Results The prevalence of diabetes among tuberculosis cases ranged from 4.5% to 13.4% in the municipalities. Evidence of an association was observed between tuberculosis/diabetes comorbidity and female population, age of 61 years or more, low schooling, negative HIV/AIDS, longer treatment time, self-administered treatment and cure. Conclusion The study showed a greater cure outcome in the profile of people with tuberculosis/diabetes comorbidity, even among those on a self-administered regime, which could favor the development of specific guidelines for the management of tuberculosis in these people.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Omer Abdelbagi ◽  
Imad R. Musa ◽  
Shaza M. Musa ◽  
Salim A. ALtigani ◽  
Ishag Adam

Abstract Background Hypertension and diabetes mellitus (DM), are highly prevalent worldwide health non-communicable diseases, and are associated with chronic complications. The co-existence of both conditions accelerates the related complications and increases morbidities and mortalities. A cross-sectional study was conducted in Nahr an Nil State (River Nile State) in Sudan between May and August 2018 to identify the prevalence of hypertension and risk factors among patients with DM in that region. Results The median (interquartile) age of the 1,973 enrolled patients was 58.0 (50.0‒65.0) years, and 818 (45.6%) were males. The median (interquartile) duration of diabetes was 5.0 (3.0‒9.0) years. Of the 1,973 enrolled participants, 21.7%, 1.3%, 37.1%, and 39.9% were normal weight, underweight, overweight, and obese, respectively. Of 1,973 854 (47.6%) patients also had hypertension. Logistic regression analyses showed that elderly patients (adjusted odds ratio [AOR] = 1.03, 95%; confidence interval [CI] = 1.02‒1.04), males (AOR = 2.96, 95%; CI = 2.15‒4.07), employed patients (AOR = 1.92, 95%; CI = 1.38‒2.70), obese patients (AOR = 1.59, 95%; CI = 1.21‒2.08), and patients with diabetic foot (DF) (AOR = 2.45, 95%; CI = 1.72‒3.47) were at higher risk for hypertension. Conversely, patients with Type 2 DM (T2DM) (AOR = 0.63, 95%; CI = 0.50‒0.80) were at lower risk for hypertension. There was no significant association between overweight, uncontrolled DM, and hypertension. Conclusion This study showed a high prevalence of hypertension among patients with DM. Notably, older age, male gender, employment, duration of DM, DF, underweight, and obesity were significant predictors of hypertension among patients with DM.


Author(s):  
Birendra Babu Yadav ◽  
Shivaswamy M. S. ◽  
M. D. Mallapur

Background: Diabetes threatens to assume pandemic level by 2030 and there is no available statistics of type2 diabetes mellitus on non-teaching staff. The risk factors like bad habits, family history, waist hip ratio (≥ 0.9 in males and ≥0.85 in females), BMI (≥28) and IDRS (>60) all attributed to the high prevalence of pre-diabetic as well as diabetes. Aims: To know the prevalence of Type 2 Diabetes Mellitus among non-teaching staff and to determine the risk factors associated with it.Methods: A facility based cross – sectional study was conducted among all the non-teaching staff of Jawaharlal Nehru Medical College, Belagavi from February to October 2014.A total 500 (394 males and 106 female) participants between age group 20-59 years were selected for the study. After taking written informed consent, information regarding socioeconomic and risk factors were collected though pre – tested questionnaire. Physical examination were done to calculate BMI, Waist –Hip ratio and IDRS (Indian diabetes risk score). The random blood sugar was estimated to identify the diabetes and pre-diabetics. Results: The overall prevalence of diabetics and pre- diabetics was 5 per cent and 17 per cent respectively. The prevalence of diabetes was highest in age group 50-59 years. The risk factor like bad habit, waist hip ratio (≥0.9 in males and ≥0.85 in females), BMI (≥28) and IDRS (>60) attributed to high prevalence of pre diabetics and diabetics. Conclusions: The prevalence of diabetes was more among non-teaching staff so; both preventive and curative services should be provided to them. 


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