Efficacy of L-lysine aescinate in complex treatment of acute vascular optical neuropathy and its influence of the state of the lypophil antioxidant system

The article presents experimental data on the state of the antioxidant system in red blood cells of white outbred rats 1 and 3 months after acute mercury nitrate poisoning with a semilethal dose. It has been established that this form of intoxication is accompanied by pronounced changes in the state of the antioxidant defense system in erythrocytes of poisoned animals (a decrease in the concentration of reduced glutathione, a decrease in the activity of superoxide dismutase and glutathione peroxidase, and an increase in the concentration of lipid peroxidation products).It has been shown that the mercury content in the blood of experimental animals remains elevated during the entire study period.The results obtained indicate the importance of impaired functioning of the antioxidant system in the implementation of long-term consequences of acute mercury poisoning. The reasons for the occurrence of these biochemical shifts and their role in the development of the long-term cytotoxic effects of mercury nitrate are discussed.

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The effect of hirudotherapy on cerebral circulatory homeostasis in patients with genital endometriosis

Fizioterapevt (Physiotherapist) ◽

10.33920/med-14-2010-05 ◽

2020 ◽

pp. 58-66

Author(s):

Ya. I. Uraeva ◽

I. I. Ivanova ◽

N. N. Lazarenko ◽

E. V. Filatova ◽

I. A. Pankova ◽

...

Keyword(s):

Regression Analysis ◽

Drug Therapy ◽

Cerebral Circulation ◽

The State ◽

Control Group ◽

Complex Treatment ◽

Statistical Regression ◽

Treatment Results ◽

Standard Drug ◽

Before And After

The results of the treatment of women (n = 94) suffering from genital endometriosis are presented. The first (control, n = 30) group of women received standard drug therapy; the second (main, n = 64) group of women additionally had hirudotherapy procedures using medical leeches. The course of treatment consisted of 10–12 procedures. The state of cerebral circulation was assessed according to the rheoencephalography data before and after the treatment, as well as after 1, 3, 6, and 9 months. As a result, in patients in the 2-nd (main) group receiving complex treatment, the state of cerebral circulation improved signifi cantly. Moreover, according to the statistical regression analysis, it was possible to predict its further decrease by two periods ahead, compared with the treatment results in patients in the 1-st (control) group.

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Pathogenetic features of periodontitis as complications of orthodontic treatment

Medical alphabet ◽

10.33667/2078-5631-2021-24-64-68 ◽

2021 ◽

pp. 64-68

Author(s):

A. К. Sheregov ◽

М. S. Mustafayev ◽

Z. F. Kharaeva

Keyword(s):

Orthodontic Treatment ◽

The State ◽

Complex Treatment ◽

Periodontal Tissues ◽

Different Levels

The article presents the results of clinical and microbiological studies and immunological features of the state of periodontal tissues in patients with moderate periodontitis, which developed as a complication of orthodontic treatment. It was found that at the later stages of orthodontic treatment with the development of periodontitis, a complex of persistent changes in the periodontal tissues at different levels of pathogen-esis was revealed in patients. In this connection, in order to plan the complex treatment of patients with periodontitis, which has developed as a complication of orthodontic treatment, and to predict the course of the disease, it is necessary to influence the established and mutually supportive links and indicators of pathogenesis.

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THE STATE OF THE ANTIOXIDANT SYSTEM OF THE INTERNAL ORGANS IN RATS DURING BURN DISEASE

Bulletin of Siberian Medicine ◽

10.20538/1682-0363-2014-3-51-55 ◽

2014 ◽

Vol 13 (3) ◽

pp. 51-55

Author(s):

L. G. Netyukhailo ◽

T. A. Sukhomlin ◽

Ya. A. Basarab ◽

V. V. Bondarenko ◽

S. V. Kharchenko

Keyword(s):

Lipid Peroxidation ◽

Superoxide Dismutase ◽

Free Radical ◽

Salivary Glands ◽

Antioxidant System ◽

The State ◽

Antioxidant Systems ◽

Free Radical Processes ◽

Burn Disease ◽

Radical Processes

The objective of research was to study the state of prooxidant and antioxidant systems in the tissues of the lungs, kidneys, pancreas and salivary glands at burn disease. The intensity of the free radical processes was evaluated on the basis of the content of malondialdehyde (MDA) and antioxidant system – based on the indexes of its enzymatic chain: superoxide dismutase and catalase in homogenates of the studied organs. It has been found that changes in experimental burn disease depend on the studied organs and the stage of burn disease. The activation of free radical processes observed in all investigated organs (lungs, kidneys, pancreas and salivary glands). Reactive oxygen species induce lipid peroxidation, which is a universal marker of tissue damage. MDA appears in the body during degradation of polyunsaturated fatty acids and it’s a marker of lipid peroxidation and oxidative stress. It was found the increasing of MDA in all organs, especially in the lungs and kidneys at stage of burn shock. Under these conditions it was observed the decrease of superoxide dismutase and catalase in all investigated organs. At burn disease there is development of disbalance between the action of prooxidant and antioxidant systems due to the activation of free radical processes.

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Hydrolytic enzymes in therapy of gestosis

Journal of obstetrics and women s diseases ◽

10.17816/jowd89529 ◽

2021 ◽

Vol 50 (2) ◽

pp. 76-79

Author(s):

K. A. Gabelova

Keyword(s):

Blood Pressure ◽

Immune Complexes ◽

Clinical Effect ◽

Hydrolytic Enzymes ◽

Clinical Effectiveness ◽

The State ◽

Complex Treatment ◽

Traditional Therapy ◽

Positive Clinical Effect

The clinical effectiveness o f complex enzymotherapy with preparation Vobenzim in treatment o f gestosis was studied in comparison with traditional therapy. The author analyzes the course оf gestation and delivery, and the state оf neonates in women with nephropathy o f I degree, who got common treatment (28 patients) and complex treatment including Vobenzim (17patients). Positive clinical effect o f complex enzymotherapy in case o f nephropathy is displayed in decreasing of edematic syndrome, eliminating or decreasing o f proteinuria, lowering o f blood pressure and impairment o f fetalhypoxia in labors. It goes along with the reduction o f immune complexes fixed in placenta.

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The state of the blood antioxidant system in the patients presenting with acromegaly

Problems of Endocrinology ◽

10.14341/probl20156128-11 ◽

2015 ◽

Vol 61 (2) ◽

pp. 8-11

Author(s):

M V Faassen ◽

M S Pankratova ◽

N N Molitvoslovova ◽

A A Baizhumanov ◽

S S Kovalenko ◽

...

Keyword(s):

Oxidative Stress ◽

Antioxidant Activity ◽

Superoxide Dismutase ◽

Blood Plasma ◽

Antioxidant System ◽

The State ◽

Total Antioxidant Activity ◽

Sod Activity ◽

Protein Thiols ◽

Total Antioxidant

The state of the blood antioxidant system in the patients presenting with acromegaly. The objective of the present study was to evaluate the total antioxidant activity (TAA) of blood plasma, the levels of non-protein thiols and 2-thyobarbituric acid-active products (TBA-AP), superoxide dismutase (SOD) and catalase (CAT) activities as well as ceruloplasmin (CP) level in the patients presenting with acromegaly. It was shown that plasma TAA and SOD activity in this patients was on the average 20 and 30% lower respectively than in the control subjects. At the same time, the TBA-AP and CP levels increased by 50 and 40% respectively. These data suggest the development of oxidative stress in the acromegalic patients.

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The Experience of Studying the State of Occlusal Relations in Patients with Generalized Periodontitis Who Require Orthopedic Treatment with Non-Removable Structures Using the “T-Scan system”

Galician Medical Journal ◽

10.21802/gmj.2018.3.6 ◽

2018 ◽

Vol 25 (3) ◽

Author(s):

Arsen Melnychuk

Keyword(s):

Poor Quality ◽

The State ◽

Complex Treatment ◽

Orthopedic Treatment ◽

Prosthetic Group ◽

Computerized Analysis ◽

Group I ◽

Left And Right ◽

Definition Of ◽

The Ideal

Determining the state of occlusal relations in orthopedic dentistry is an important step both for diagnosis and for treatment. For the purpose of their study, 65 patients with chronic GP of theІst and ІІnd degree of the development who needed an orthopedic treatment, were used the device “T-Scan III”. Patients had a partial (1-3) loss of teeth of III and IV classes according toKennedy; they were divided into two groups. Group I included 35 patients who had included defects and were not previously prosthetic, group II – 30 patients who had poor-quality bridges of different materials that needed replacement. Control was provided by 20 dentally healthy patients with normal occlusal ratios of dentitions.We have determined that patients with GP with included defects in the dentition have significant deviations from the even distribution of occlusalloading on the dental rows in both of the studied classes according to Kennedy, especially those who had not previously been prosthetic. It is necessary to use a computerized analysis of occlusion with the help of the apparatus “T-Scan III” to all of these patients at every orthopedic stage of complex treatment. The precise definition of supra-contacts reduces the possibility of errors and allows achievement of the ideal – 50% to 50% –relationship between the left and right parts of the tooth-jaw system during fitting and fixing of orthopedic structures and keeping it in the process of their exploitation.

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