scholarly journals COVID-19 Detection by Salivary Analysis: Easy and Reliable Approach in Massive Outbreak

2020 ◽  
Vol 5 (1) ◽  
pp. 7
Author(s):  
Dipayan Mojumder ◽  
Satabdi Paul ◽  
Ruman Banik ◽  
Hasina Mahmuda Ferdushi
Keyword(s):  
Body Fluid ◽  
Saliva Sample ◽  
Underlying Mechanism ◽  
Nasopharyngeal Swab ◽  
The World ◽  
Diagnostic Capability ◽  
Targeted Drug ◽  
Novel Coronavirus ◽  
Almost All ◽  
Pcr Test

Coronavirus disease (COVID-19) caused by 2019 Novel Coronavirus (2019-nCoV) recently emerged from Wuhan, Hubei province, China in December 2019. It showed devastating nature and already involved almost all the territories all over the world. It is a contagious disease and rapid, reliable diagnosis is needed to take measure for decreasing the infection rate. For detection of COVID-19 nasopharyngeal swab, sputum, bronchoalveolar lavage, saliva and other body fluid identified as useful samples. The aim of this review from recent studies is to explore the possibility of salivary analysis to identify COVID-19. Although nasopharyngeal swab is taken for rRT-PCR test as a worldwide accepted method, but it is a technique sensitive procedure needs expert personnel and adequate protection is necessary to avoid contamination. In the contrary, saliva sample can be taken easily by the patient himself at home which is a low-risk procedure and economical. So, in the pandemic of COVID-19, salivary analysis could be a good option for detection. Future study on this might explore the possible diagnostic capability of saliva for different diseases and underlying mechanism to find out the pathway for targeted drug therapies.International Journal of Human and Health Sciences Vol. 05 No. 01 January’21 Page: 7-11

scholarly journals POS1232 COVID-19 IN PATIENTS WITH SYSTEMIC SCLEROSIS: ONE RHEUMATOLOGY CENTER EXPERIENCE

2021 ◽  
Vol 80 (Suppl 1) ◽  
pp. 899.2-899
Author(s):  
M. Starovoytova ◽  
O. Desinova ◽  
L. P. Ananyeva ◽  
O. Koneva ◽  
L. Garzanova ◽  
...  
Keyword(s):  
Systemic Sclerosis ◽  
Severe Disease ◽  
High Risk Group ◽  
Nasopharyngeal Swab ◽  
Frequent Use ◽  
Diffuse Form ◽  
Novel Coronavirus ◽  
Almost All ◽  
Dose Prednisone ◽  
Frequent Presence

Background:Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2) virus infection or COVID-19 is a serious problem for patients with systemic autoimmune diseases Given the serious complications, including acute lung injury, patients with systemic sclerosis (SSc), especially SSs associated with interstitial lung disease (ILD), may represent a high risk group for infection and the development of severe COVID-19.Objectives:We present an analysis of the COVID-19 course and outcomes in 110 SSc pts.Methods:The study included 147 patients with SSc. The information was clarified by means of telephone survey after 10 months of the pandemic (December 2020). Covid-19 was diagnosed when confirmed by positive oral /nasopharyngeal swab, in the presence of positive antibodies and/or characteristic symptoms, and data from chest computed tomography (CT). 110 pts (77%) out of 147 patients in the SSc registry, gave the necessary information. COVID-19 was diagnosed in 59 pts (53 %). 42 pts (71%) had SSc-ILD. Pts mean age was 54.96 (s.d.11, min 31, max 79), 83% women (49 women and 10 men). 38 pts (65%) had a limited form of SSc, 15 (26%) pts had diffuse form SSc, 6% had overlap (SSc-polymyositis (PM) and SSc had rheumatoid arthritis (RA) and 3% had visceral form of SSc). All patients received low-dose prednisone, and more than half of the pts received immunosuppressive therapy. Rituximab therapy was performed in 24 pts (41%).Results:Almost all patients had positive swab from the oral cavity/nasopharynx. And only in 4 (7%) pts nasopharyngeal swabs were negative, in these patients specific antibodies and characteristic CT changes were detected. Chest CT was performed in 51 (86%) pts. Novel coronavirus pneumonia developed in the vast majority of pts - in 46 (78 %) pts. CT1 (up to 25% of lung lesions) had 10 (17%) pts, CT2 (25-50%) – 21(36%) pts, CT 3 (50-75%) – 15(25%) pts. In 5 (8.5%) pts no changes were detected on CT. The course of COVID-19 was mild and moderate (20 (34%) pts and 18 (31%) pts respectively), severe course was observed in 21 (35%) pts, including fatal in 12 (20%) pts. Among the deceased pts, only 1 patient with SSc-PM had not had ILD, but 7 patients had been treated with rituximab.Conclusion:SSc SARS-CoV-2-infected patients may be at risk of severe disease and mortality due to the frequent presence of ILD and the frequent use of immunosuppressive, including biological, therapy.Disclosure of Interests:None declared

The Impact of COVID-19 on Stock Markets

2022 ◽  
pp. 250-262
Author(s):  
Aslı Aybars ◽  
Mehtap Öner
Keyword(s):  
Literature Review ◽  
Financial Markets ◽  
Stock Returns ◽  
Empirical Studies ◽  
The Novel ◽  
The World ◽  
Fast Pace ◽  
Novel Coronavirus ◽  
Almost All ◽  
The Impact

The novel coronavirus, COVID-19, which emerged at the end of 2019 and spread to the world at a very fast pace, resulted in a pandemic affecting the finance industry besides many other industries though at varying extents. Financial markets, which can be regarded as cornerstones of each and every country's economic success, have been adversely influenced due to the fear and uncertainty arising with the emergence of the novel coronavirus at different degrees. This chapter provides a summary of a literature review based on the impact of this pandemic on stock returns and volatility in the stock exchanges of different countries and regions of the world. What has been captured as a result of this literature review is that almost all of the financial markets around the world have been influenced due to the virus. Further, industry-wise empirical studies demonstrate that not all industries are affected at the same level or even in the same direction.

scholarly journals Rash in COVID-19

2020 ◽  
Vol 1 (6) ◽  
pp. 01-02
Author(s):  
Shravan Kooragayalu
Keyword(s):  
Skin Rash ◽  
Systemic Disease ◽  
Interesting Case ◽  
The Body ◽  
Limited Data ◽  
Short Course ◽  
The World ◽  
Novel Coronavirus ◽  
Almost All ◽  
High Index Of Suspicion

In December 2019, unexplained cases of pneumonia were reported in Wuhan, China. A novel coronavirus named Severe Acute Respiratory Syndrome coronavirus-2 (SARS CoV-2) was isolated from respiratory tract of patients, and the resultant disease was termed as COVID-19 (Coronavirus Disease 2019) (Jin YH 2020). COVID-19 has spread throughout china and across the world and it was declared as a pandemic by March 11th 2020 (Ng OT 2020). Running Title: COVID-19 is a systemic disease that could affect almost all parts of the body but it primarily affects the respiratory system. There is very limited data in the literature about the dermatological manifestations of COVID-19. An interesting case of skin rash in a patient who was critically ill with COVID-19 is presented here. The skin rash improved after short course of treatment with steroids. It is recommended that clinicians have a high index of suspicion to COVID-19 disease in patients who develop unexplainable rash.

scholarly journals Nonlinear Markov Chain Modelling of the Novel Coronavirus (Covid-19) Pandemic

2020 ◽  
Author(s):  
Muammer Catak ◽  
Necati Duran
Keyword(s):  
Markov Chain ◽  
Markov Chains ◽  
Markov Chain Model ◽  
Chain Model ◽  
The Novel ◽  
The World ◽  
The Usa ◽  
Novel Coronavirus ◽  
Almost All ◽  
Markov Chain Modelling

Almost all countries around the world are struggling against the novel coronavirus (Covid-19) pandemic. In this paper, a nonlinear Markov chains model is proposed in order to analyse and to understand the behaviour of the Covid-19 pandemic. The data from China was used to build up the presented model. Thereafter, the nonlinear Markov chain model is employed to estimate the daily new Covid-19 cases in some countries including Italy, Spain, France, UK, the USA, Germany, Turkey, and Kuwait. In addition, the correlation between the daily new Covid-19 cases and the daily number of deaths is examined.

scholarly journals Impact of COVID-19 Outbreak on Financial Reporting in the Light of the International Financial Reporting Standards (IFRS) (An Empirical Study)

2020 ◽  
Vol 5 (2) ◽  
pp. p21
Author(s):  
Hasan El-Mousawi ◽  
Hasan Kanso
Keyword(s):  
Financial Reporting ◽  
Global Economy ◽  
Certified Public Accountants ◽  
The Novel ◽  
Financial Reporting Standards ◽  
The World ◽  
Public Accountants ◽  
Novel Coronavirus ◽  
Almost All ◽  
The Impact

The outbreak of a novel type of Coronavirus (COVID-19) in the majority of countries around the world has had many negative implications on almost all aspects of life. Currently, about a quarter of the population of Earth is quarantined at their homes, social distancing is effective everywhere, almost all industries have ceased their activities, and various businesses are either closed down or working from home. Procedures taken by governments or local authorities to improve their ability to contain the outbreak have impacted the global economy, which in turn will have many consequences on financial reporting of organizations. This study examines the impact of the novel Coronavirus outbreak on financial reporting of organizations from the viewpoint of Certified Public Accountants in Lebanon. The researchers have used a descriptive-analytical approach and have constructed a well-structured five-point Likert style questionnaire as the study tool. The questionnaire was distributed to a sample chosen from the population of certified public accountants in Lebanon. The random sample consisted of 300 practitioners of the profession, and 221 of them responded; all of which were valid for testing and analysis. The study reached some important findings mainly that the COVID-19 outbreak has had a significant impact on the financial reporting of businesses according to the opinions of Certified Public Accountants (CPAs) in Lebanon, and the researchers had some recommendations as a result.

scholarly journals Overview of COVID-19 Pandemic: Transmission, Epidemiology and Diagnosis

2021 ◽  
pp. 174-181
Author(s):  
Akoijam Nisha Devi
Keyword(s):  
Current Knowledge ◽  
Age Groups ◽  
Severe Form ◽  
Disease Spread ◽  
High Morbidity ◽  
The World ◽  
Novel Coronavirus ◽  
Wet Market ◽  
Almost All ◽  
The City

In the early part of the last month of the year 2019, suddenly many people started suffering from a new respiratory disease in the city of Wuhan in China. At that time the cause of the disease was not known. The disease was caused by a new coronavirus which was never detected in the past. WHO called it the novel coronavirus 2019. Later the virus was named as severe acute respiratory syndrome coronavirus 2. The disease is considered to have originated from the wet market located in the city of Wuhan in China. It came from the bats and infected the humans and possibly with an intermediate host like the pangolins. From the place it originated the disease spread to other places within China and to other countries outside China. WHO recognised the disease as a pandemic, as the disease spread to other parts of the world in Europe and Asia. This pandemic has affected the mankind as never before. More than 110 million people are confirmed infected with this disease. More than 2.5 million people have succumbed to this devastating disease. The pandemic has affected almost all the countries in the world. At a time when many countries were in lockdown mode, it seemed the world had come to a standstill. Individuals of both sexes belonging to all age groups can get infected, although old persons and persons with co-morbid conditions are more prone to get infected and also has more chance to develop severe form of this disease carrying high morbidity and mortality. In this review, the literature of the causative agent, epidemiology, mode of transmission, diagnosis and treatment and preventive strategies are reviewed, so that the reader is provided with sufficient current knowledge about this disease.

scholarly journals COVID-19; An Update on the Novel Coronavirus SARS-CoV-2 Pandemic

2020 ◽  
Vol 13 (1) ◽  
pp. 5-8
Author(s):  
Subarna Chakravorty
Keyword(s):  
The Novel ◽  
National Library ◽  
Research Activity ◽  
Medicine Research ◽  
The World ◽  
Novel Virus ◽  
Novel Coronavirus ◽  
Almost All ◽  
Global Research

In an unprecedented show of scientific solidarity and collaboration across the globe, research on the novel SARS-CoV-2 (Covid-19) virus has progressed at a pace that could almost match the virus’s relentless movement through communities. This has been a pandemic like no other. Whilst it is hard to speculate how the world will emerge at the end of this, there is little doubt that scientists are trying to rise up to its challenge in a way that has never been seen before. As of the 21st of March 2020, the National Library of Medicine research repository has a collection of nearly 1000 articles on Covid-19, a novel virus whose genome was sequenced less than 12 weeks ago12. Almost all these articles were published in February and March 2020, reflecting the explosion of global research activity on this virus.

scholarly journals nCOVID-19: Social and Economic Impacts

2021 ◽  
Author(s):  
Amitkumar V. Jha ◽  
Bhargav Appasani
Keyword(s):  
Public Health ◽  
Public Health System ◽  
The Novel ◽  
Wuhan City ◽  
The Public ◽  
The World ◽  
Pros And Cons ◽  
Novel Coronavirus ◽  
Almost All ◽  
Economical Losses

The Novel Coronavirus Disease (nCOVID) has grabed the whole world recently since its origin in Wuhan city of China. There is very dire consequences the whole world is going through because of nCOVID. The unprecedented nCOVID and associated consequences pushed the public health system in the crisis. Undoubtedly, it has affected almost all countries of the world. Nevertheless, hardly a few country it has spared from its dire consequences in terms social and economical losses. However, it is worth of observing that some of the positive consequences are also results of this pandemic. Consequently, this paper discusses the pros and cons of the pandemic from various perspective such as social and economical impacts on human lives and livelihoods.

scholarly journals Novel Coronavirus: A Newly Arranged Mini-Review

2020 ◽  
Vol 3 (Special-1) ◽  
pp. 130-135
Author(s):  
Siwani Devi ◽  
Kishan Tripathi ◽  
Mohammad Mukim ◽  
Vidhi Jain ◽  
Nesar Ahmad ◽  
...  
Keyword(s):  
Preventive Measures ◽  
The Elderly ◽  
Spread Rate ◽  
Specific Therapy ◽  
Rapid Spread ◽  
The World ◽  
Large Populations ◽  
Global Concern ◽  
Novel Coronavirus ◽  
Almost All

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which was originally known as a virus that infects animals and rarely can be transmitted to humans in large populations, is now transformed into one of the most feared pandemics causes worldwide. Infection by a virus that is officially known as COVID-19 has caused global concern mainly due to the number of deaths caused. Since it was first reported in Wuhan, China in December 2019, now COVID-19 has spread to almost all parts of the world with a very rapid spread rate. The main symptom of this infection is a respiratory disease accompanied by other symptoms that resemble flu-like illness. Everyone can suffer from COVID-19, but the elderly, toddlers, pregnant women, and people with certain diseases and disorders of the immune system show more severe symptoms. The disease is transmitted through inhalation or contact with droplets, where the incubation period ranges from 2 to 14 days. Until now, specific therapy to treat COVID-19 has not been found, with preventive measures taken to control its spread. In this mini-review, we will explain important information related to COVID-19.

scholarly journals Cardiovascular Surgery Residency Program during COVID-19 pandemic:

2021 ◽  
Author(s):  
Gustavo Guerreiro ◽  
Lucas Cardoso ◽  
Valdano Manuel ◽  
Aldo Benitez ◽  
Lucas Bonamigo ◽  
...  
Keyword(s):  
Medical Training ◽  
World Health ◽  
New Professionals ◽  
Residency Programs ◽  
The World ◽  
Novel Coronavirus ◽  
Health Organization ◽  
Almost All ◽  
Surgery Residency Program ◽  
Based Medicine

In December 2019, the novel coronavirus disease 2019 (COVID-19) emerged in China and spread rapidly around the world, resulting in a pandemic declared by the World Health Organization in March 2020. The disease has affected more than 11 million people in Brazil, with more than 265.000 deaths to date, as we are now facing a second wave of infections. Regarding medical assistance and training, it turned out to be a great challenge, since - among other things - many residents were relocated to respiratory units to treat patients with COVID-19. Even though the residency programs situation has become chaotic all around the world and the activities in almost all specialties nearly stopped (especially in surgical specialties), the need to reinvent the way of teaching was the best concern. Worldwide the “webinars fever” was an impulse to try new strategies to fulfill the gaps of knowledge of these future specialists. It is crucial to call to the responsibility put on medical training institutions to prepare these new professionals according the principles of evidence-based medicine, surgical proficiency and patient safety.

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