scholarly journals Glycaemic Control, Lipid Profile, Blood Pressure and Body Weight Status Among Diabetics in Rural Malaysia

2020 ◽  
Vol 8 (2) ◽  
Author(s):  
Hazizi AS ◽  
Zaitun Y ◽  
Kandiah M ◽  
Chan SP
Keyword(s):  
Blood Pressure ◽  
Body Weight ◽  
Blood Glucose ◽  
Glycaemic Control ◽  
Lipid Profile ◽  
Weight Status ◽  
Density Lipoprotein ◽  
Lipoprotein Cholesterol ◽  
Body Weight Status

Introduction: Diabetes is associated with a high risk of cardiovascular disease. The management of blood glucose, dyslipidaemia and other modifiable risk factor, is a key element in the multifactorial approach to prevent complications of type 2 diabetes. Materials and Methods: A cross sectional study was conducted to determine the level of glycaemic control, lipid profile, blood pressure and body weight status among type 2 diabetics in rural Malaysia. A total of 237 diabetic subjects participated in this study. Physical examination was carried out, including measurements of height, weight, waist and hip circumferences, and systolic and diastolic blood pressure. Fasting venous blood samples were collected to determine the glucose level and lipid profile. Results: About 70% of the subjects had a high body mass index (BMI), equal to or above 25 kg/ m2. More than 60% of the subjects had systolic blood pressure ≥ 140 mmHg and/or diastolic ≥ 90 mmHg. Mean fasting blood glucose was 9.84±4.54 mmol/L. Mean total cholesterol was 5.18±1.35 mmol/L. High density lipoprotein cholesterol (HDLC) and triglyceride (TG) and glucose levels were higher in male than in female, but not statistically significant (p>0.05). However, low density lipoprotein cholesterol (LDLC) was higher in females than males (p<0.05). Mean HDLC was below 1.0 mmol/L in all subjects. Conclusion: Glycaemic control, lipid profile, blood pressure and body weight status were not satisfactory and may increase the risk of microvascular and macrovascular complications among these subjects. Appropriate intervention programs should be implemented for better diabetes control among rural subjects.

Liraglutide effects on glycaemic control, body weight, blood pressure and lipid profile in obese patients with type 2 diabetes: real-life clinical practice

2014 ◽  
Author(s):  
Jose Carlos Fernandez-Garcia ◽  
Isabel Mancha-Doblas ◽  
Carmen Maria Cortes-Salazar ◽  
Maria Jose Picon-Cesar ◽  
Ana Maria Gomez-Perez ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Type 2 Diabetes ◽  
Body Weight ◽  
Clinical Practice ◽  
Glycaemic Control ◽  
Lipid Profile ◽  
Real Life ◽  
Obese Patients ◽  
Control Body

Chia seed (Salvia hispanica L.) supplementation to the diet of adults with type 2 diabetes improved systolic blood pressure: A randomized controlled trial

2021 ◽  
pp. 026010602098181
Author(s):  
Eman Zaid Marzouq Alwosais ◽  
Ebaa Al-Ozairi ◽  
Tasleem A Zafar ◽  
Sharifa Alkandari
Keyword(s):  
Blood Pressure ◽  
Type 2 Diabetes ◽  
Body Weight ◽  
Blood Glucose ◽  
Lipid Profile ◽  
Inflammatory Marker ◽  
Control Group ◽  
Food Ingredients ◽  
Chia Seed

Background: Functional food ingredients, such as dietary fiber, long-chain polyunsaturated fatty acids, and high-quality protein, have been shown to help control blood glucose concentration and lower high blood pressure (BP), as well as improving other cardiovascular disease risk factors. However, little research has assessed the impacts of consuming chia seeds, which are rich in these nutrients, on metabolic and physiological outcomes, and results are conflicting. Aim: The study aimed to investigate the possible effects of chia seeds on fasting blood glucose, insulin, glycated hemoglobin, BP, lipid profile, body weight, and the inflammatory marker – high-sensitivity C-reactive protein – in people with type 2 diabetes (T2DM). Methods: Adults with T2DM ( n = 42) were randomly assigned equally to the chia seed group, which consumed 40 g/day chia seeds for 12 weeks, or a control group, which did not consume any supplement. Blood samples were collected at baseline and after a 12-week intervention period to assess the study outcomes, such as glycemic control, BP, cardiovascular risk parameters including lipid profile, inflammatory marker, and body weight. Results: Adjusted for gender and baseline values, the chia seed group had systolic BP (SBP) significantly reduced compared to control [ t (1) = 2.867, p = 0.007, η 2 p = 0.174]. No differences were observed in any other parameter tested in the chia seed or control group. Conclusions: People with T2DM and hypertension, maintaining usual dietary consumption, physical activity pattern, and medications, had significantly reduced SBP compared to the control group when having consumed 40 g/d of chia seeds for 12 weeks.

scholarly journals Comparative Effects of Animal and Vegetable Fats on Lipid Profile and Patho-physiological Changes in Mice

2013 ◽  
Vol 5 (2) ◽  
pp. 353-361
Author(s):  
S. Akter ◽  
A. Miah ◽  
K. Islam ◽  
A. H. Khan
Keyword(s):  
Body Weight ◽  
Blood Glucose ◽  
Soybean Oil ◽  
Lipid Profile ◽  
Total Cholesterol ◽  
Control Diet ◽  
Density Lipoprotein ◽  
Diet Group ◽  
Normal Diet ◽  
Lipoprotein Cholesterol

Dietary intake of high amounts of animal fats can cause hypercholesterolemia whereas plant fat like soybean oil reduces serum cholesterol and lipoproteins in mice. The effects of animal fat (butter) and plant fat (soybean oil) fortified diet on lipid profile (serum total cholesterol, low density lipoprotein-cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C), and triglycerides), body weight, blood glucose and on tissue texture were investigated in mice. 30 Swiss albino mice were divided equally into three groups. Mice were fed a normal diet (untreated control), a high-fat diet (5% butter) (butter group) and an unsaturated fat diet (5% soybean oil) (soybean oil group) for 90 days. Mice of butter group showed significantly increased level of total cholesterol, LDL-C and triglycerides and decreased level of HDL-C in the serum but not found in mice of soybean fed diet group. Body weight and blood glucose were also markedly elevated in mice fed only butter enriched diet. Histological analysis of liver at the end of 90 days showed increased fat deposition in the mice fed with butter diet than those of control diet and plant fat diet group. Mice fed with butter showed an elevation of lipid levels and developed fatty changes in liver.Keywords: Butter; Soybean oil; Lipid profile; Fatty change; Mice.© 2013 JSR Publications. ISSN: 2070-0237 (Print); 2070-0245 (Online). All rights reserved.doi: http://dx.doi.org/10.3329/jsr.v5i2.11909        J. Sci. Res. 5 (2), 353-361 (2013)

scholarly journals Anthropometric Measureme nts, Dietary Intake and Lipid Profile of Hypertensive Young Adults (25-35 years): A Comparison Between Vegetarians and Non Vegetarians

2014 ◽  
Vol 2 (3) ◽  
pp. 122-130
Author(s):  
Prajakta Nande
Keyword(s):  
Blood Pressure ◽  
Body Weight ◽  
Young Adult ◽  
Lipid Profile ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Lipoprotein Cholesterol ◽  
Low Density ◽  
Low Density Lipoprotein Cholesterol ◽  
The Impact

Increasing prevalence of hypertension is a major health concern.Dietary habits and food choices play an important role in maintaining lipid levels.The aim of this study was to investigate the impact of dietary habits on lipid profile of young adult hypertensive males. Two hundred vegetarians (V) and two hundred non vegetarians (NV) stage I hypertensive young adult men from age group 25-35 yrs. Anthropometric indices like weight, height, waist circumference (WC), hip circumference (HC) and mid-upper-arm circumference (MUAC) were measured. Body mass index (BMI) and waist hip ratio (WHR) were computed using standard equations. 24 hour’s food intake data for each subject was collected for consecutive 3 days and energy and energy yielding nutrients were computed. Total cholesterol (T-C), low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C) and triglyceride (TG) levels were estimated. Very low density lipoprotein cholesterol (VLDL-C) was computed using standard equation.Insignificant difference was noticed between V and NV for BMI, WC and HC. In contrast, MUAC of NV was found to be significantly higher than V. NV had higher mean daily intake of energy, protein and fat but low mean daily consumption of carbohydrate as compared to V.NV had higher mean values of systolic blood pressure (SBP) (p>0.05) and diastolic blood pressure (DBP) (0.01<p<0.05) than V. 30% NV were obese grade II. TC and LDL-C of NV were greater than V but HDL-C and TG of V were greater than NV (p>0.05). TC, LDL-C and VLDL-C among NV correlated positively (p<0.01) with body weight (r 0.5340, 0.4841 and 0.5921, respectively). Stronger relationships existed between HDL-C and body weight among both groups. BP, BMI and MUAC were more among NV than V. V showed better lipid profile than NV. This could be attributed to higher intake of energy and fat among NV.

scholarly journals Relationship of Glycated Haemoglobin with Lipid Profile among Patients with Type 2 Diabetes Mellitus

2017 ◽  
Vol 7 (1) ◽  
pp. 43-47 ◽  
Author(s):  
Tasrina Shamnaz Samdani ◽  
Palash Mitra ◽  
Muhammad Abdur Rahim
Keyword(s):  
Type 2 Diabetes ◽  
Blood Glucose ◽  
Lipid Profile ◽  
Significant Positive Correlation ◽  
Fasting Blood Glucose ◽  
Density Lipoprotein ◽  
Lipoprotein Cholesterol ◽  
Diabetic Patients ◽  
Positive Correlation

Background: Glycated hemoglobin (HbA1c) is widely used as an index of mean glycaemia, a measure of risk for the development of diabetic complications and a measure of the quality of diabetes care. Patients with type 2 diabetes have an increased prevalence of dyslipidemia. Treatment of dyslipidaemia improves cardiovascular outcomes. The aim of this study was to determine the impact of glycemic control on lipid profile.Methods: This cross-sectional study was conducted among 300 type 2 diabetic patients admitted in BIRDEM General Hospital from November 2013 to April 2015. Fasting blood samples were collected and different lipid fractions along with fasting blood glucose and HbA1c were estimated. Pearson’s correlation test was applied to evaluate the correlation between HbA1c and components of lipid profile.Results: The mean value of total cholesterol (TC), triglyceride (TG), low density lipoprotein-cholesterol (LDLC), fasting blood glucose (FBG) and HbA1c were higher and high density lipoprotein-cholesterol (HDL-C) was lower in females when compared with these values for males. HbA1c had significant positive correlation with LDL-C (p=0.045) and negative correlation with HDL-C (p=0.024). Serum lipid profile and glycaemic controls were significantly (p=0.000) better in older age group (age ? 50 years).Conclusions: Significant positive correlation of HbA1c with lipid profiles specially LDL-C suggested that HbA1c can also be used as predictor of dyslipidemia in addition to glycemic control.Birdem Med J 2017; 7(1): 43-47

scholarly journals Sudanese diabetics with hypertension are at high risk for cardiovascular disease

2021 ◽  
Vol 9 (3) ◽  
pp. 44-48
Author(s):  
Dr. Nahla Ahmed Mohamed Abderahman ◽  
Mohamed Ahmed Ibrahim ◽  
Abderrhman Ahmed Mohamed Ismeil ◽  
Nassreldeen Khalid Abderahman Adam
Keyword(s):  
Blood Pressure ◽  
Cardiovascular Disease ◽  
Blood Glucose ◽  
High Risk ◽  
Lipid Profile ◽  
Density Lipoprotein ◽  
Lipoprotein Cholesterol ◽  
Hypertensive Patients ◽  
Increased Risk ◽  
The Mean

Objectives: To measure blood glucose, lipid profile levels, and blood pressure in diabetic hypertensive patients in order to identify the association between the parameters measured and an increased risk of cardiovascular risk in the Sudanese diabetic hypertensive patients. Material and methods: During the months of April 2012 and March 2013, a case-control study was employed in Gezira State, Sudan. The study enrolled 200 patient who met the participation criteria, with respondents divided into diabetic hypertensive and non-diabetic categories to estimate fasting blood glucose levels (FBG), Glycosylated hemoglobin (HbA1C) and lipid profile which include; total cholesterol (TC), high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C) and triglycerides (TG). The random access auto-analyzer bio system, A15 was used to test samples for various biochemical parameters. Individual information, as well as anthropometric and biochemical measurements were collected on a questionnaire. After each participant gave verbal consent, venous blood samples were drawn after an overnight fast. The statistical evaluation was achieved with the aid of a statistical package for social sciences (SPSS version 16, Chicago, IL, USA). Result: The WC and BMI both increased significantly by (p=<0.0001), according to the analysis of variance (ANOVA). FBG and HbA1C levels were significantly elevated by (p=<0.0001). The increase in systolic blood pressure (SBP) was significant by (p=<0.0001). The mean HDL-C level was at high risk (49.73) with a significant increase by (p=0.009). The mean LDL-C concentration was above the optimum level (109.03) with a non-significant increase (p=0.697). Conclusion: WC, BMI, DBP, FBG, and HDL-C all increased significantly. Diabetic- hypertensive participants were at a high risk of develops dyslipidemia and cardiovascular disease.

Effect of Honey & Olive Oil Supplemented Bio-Yoghurt Feeding on Lipid Profile, Blood Glucose and Hematological Parameters in Rats

2019 ◽  
Vol 15 (2) ◽  
pp. 140-147
Author(s):  
Magdy M. Ismail ◽  
El-Tahra M. Ammar ◽  
Abd El-Wahab E. Khalil ◽  
Mohamed Z. Eid
Keyword(s):  
Body Weight ◽  
Weight Gain ◽  
Blood Glucose ◽  
Olive Oil ◽  
Body Weight Gain ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Lipoprotein Cholesterol ◽  
Low Density ◽  
Low Density Lipoprotein Cholesterol

Background and Objective: Yoghurt, especially bio-yoghurt has long been recognized as a product with many health benefits for consumers. Also, honey and olive oil have considerable nutritional and health effects. So, the effect of administration of yoghurt made using ABT culture and fortified with honey (2 and 6%), olive oil (1 and 4%) or honey + olive oil (2+1 and 6+4% respectively) on some biological and hematological properties of rats was investigated.Methods:The body weight gain, serum lipid level, blood glucose level, serum creatinine level, Glutamic Oxaloacetic Transaminase (GOT) activity, Glutamic Pyruvic Transaminase (GPT) activity, leukocytes and lymphocytes counts of rats were evaluated.Results:Blending of bio-yoghurt with rats&#039; diet improved body weight gain. Concentrations of Total plasma Cholesterol (TC), High-Density Lipoprotein cholesterol (HDL), Low-Density Lipoprotein cholesterol (LDL), Very Low-Density Lipoprotein cholesterol (VLDL) and Triglycerides (TG) significantly lowered in plasma of rats fed bio-yoghurt. Levels of TC, LDL, VLDL, and TG also decreased in rat groups feed bio-yoghurt supplemented with honey and olive oil. LDL concentrations were reduced by 10.32, 18.51, 34.17, 22.48, 43.30% in plasma of rats fed classic starter yoghurt, ABT yoghurt, ABT yoghurt contained 6% honey, ABT yoghurt contained 4% olive oil and ABT yoghurt contained 6% honey + 4% olive oil respectively. The blood glucose, serum creatinine, GOT and GPT values of rats decreased while white blood cells and lymphocytes counts increased by feeding bioyoghurt contained honey and olive oil.Conclusion:The findings enhanced the multiple therapeutic effects of bio-yoghurt supplemented with honey and olive oil.

scholarly journals ASSOCIATION BETWEEN BLOOD LIPID PROFILE AND BLOOD GLUCOSE LEVELS IN MEN WITH CORONARY HEART DISEASE, METABOLIC SYNDROME, AND TYPE 2 DIABETES MELLITUS

2013 ◽  
Vol 12 (5) ◽  
pp. 29-33
Author(s):  
S. A. Matveeva
Keyword(s):  
Blood Glucose ◽  
Lipid Profile ◽  
Low Density Lipoprotein ◽  
Fasting Blood Glucose ◽  
Density Lipoprotein ◽  
Blood Lipid ◽  
Lipoprotein Cholesterol ◽  
Blood Lipid Profile ◽  
Glucose Levels ◽  
Blood Glucose Levels

Aim.To study the associations between blood lipid profile and blood glucose levels in men with coronary heart disease (CHD), stable effort angina (SEA), metabolic syndrome (MS), and Type 2 diabetes mellitus (DM-2).Material and methods.The study included 82 men (mean age 50,5±0,9 years) with CHD, Functional Class I–III SEA, MS, and DM-2. The following lipid profile parameters were assessed: total cholesterol (TCH), triglycerides (TG), low-density lipoprotein cholesterol (LDL–CH), very low-density lipoprotein cholesterol (VLDL–CH), high-density lipoprotein cholesterol (HDL–CH), atherogenic index (AI), and triglyceride index (TGI), together with fasting blood glucose.Results.There were positive (direct) associations between higher levels (>90th percentile) of lipid profile parameters (TCH, TG, LDL–CH, VLDL– CH, HDL–CH, AI, TGI) and blood glucose, as well as between lower levels (≤10th percentile) of lipid profile parameters (TCH, TG, LDL–CH, VLDL– CH, AI, TGI) and blood glucose. At the same time, there were negative (inverse) associations between lower lipid levels (≤10th percentile of TCH, TG, LDL–CH, VLDL–CH, HDL–CH, AI, TGI) and higher glucose levels (>90th percentile), as well as between higher lipid levels (>90th percentile of TCH, TG, LDL–CH, VLDL–CH, HDL–CH, AI, TGI) and lower glucose levels (≤10th percentile).Conclusion.Dyslipidemia and hyperglycemia demonstrate synergetic proatherogenic effects in patients with CHD, SEA, MS, and DM-2, as suggested by significant heterogeneous (direct and inverse) associations between lipid profile parameters and fasting blood glucose. The results obtained provide an opportunity for the assessment of risk levels, prognosis, and need for pharmacological prevention and treatment in patients with combined cardiovascular pathology. 

scholarly journals Weight cycling is associated with adverse cardiometabolic markers in a cross-sectional representative US sample

2020 ◽  
pp. jech-2019-213419
Author(s):  
Lisa Kakinami ◽  
Bärbel Knäuper ◽  
Jennifer Brunet
Keyword(s):  
Blood Pressure ◽  
Insulin Sensitivity ◽  
Weight Status ◽  
Density Lipoprotein ◽  
Normal Weight ◽  
Lipoprotein Cholesterol ◽  
Weight Cycling ◽  
Cross Sectional ◽  
Weight History ◽  
Cardiometabolic Markers

BackgroundWhether weight cycling (repeated weight loss and regain) is associated with cardiometabolic health is unclear. Study objective was to examine whether weight cycling since young adulthood (ie, 25 years of age) was associated with cardiometabolic markers.MethodsData from a nationally representative cross-sectional US sample (National Health and Nutrition Examination Survey, 1999–2014) were used. Weight history was based on self-reported weight at age 25, 10 years prior and 1 year prior to the survey (n=4190, 51% male). Using current self-reported weight as the anchor, participants were classified as (1) stable weight, (2) weight losers, (3) weight gainers and (4) weight cyclers. Cardiometabolic markers included fasting lipids, insulin sensitivity and blood pressure. Multiple linear regressions were used to analyse weight history (reference: stable weight) and adjusted for covariates. Analyses incorporated the sampling design and survey weights and were stratified by sex or weight status.ResultsCompared with females with stable weight, female weight cyclers had worse lipids and homeostasis model assessment for insulin resistance (HOMA-IR) (all ps<0.05). Compared with males with stable weight, male weight cyclers had worse high-density lipoprotein cholesterol (HDL) and HOMA-IR (ps<0.05). Weight cyclers with normal weight had worse HDL and low-density lipoprotein cholesterol (ps<0.05), and weight cyclers with overweight or obesity had worse HOMA-IR (p=0.05). Blood pressure was not associated.ConclusionWeight cycling is adversely associated with cardiometabolic markers but associations differ by sex and weight status. While weight cycling is consistently associated with worse cardiometabolic markers among females, results are mixed among males. Weight cycling is associated with worse lipid measures for normal weight persons, and marginally worse insulin sensitivity for those with overweight/obesity.

scholarly journals Untrained young men have dysfunctional HDL compared with strength-trained men irrespective of body weight status

2013 ◽  
Vol 115 (7) ◽  
pp. 1043-1049 ◽  
Author(s):  
Christian K. Roberts ◽  
Michael Katiraie ◽  
Daniel M. Croymans ◽  
Otto O. Yang ◽  
Theodoros Kelesidis
Keyword(s):  
Body Weight ◽  
Fat Mass ◽  
Weight Status ◽  
Density Lipoprotein ◽  
Young Men ◽  
Metabolic Health ◽  
Redox Properties ◽  
Redox Activity ◽  
Body Weight Status ◽  
The Impact

We examined the impact of strength fitness and body weight on the redox properties of high-density lipoprotein (HDL) and associations with indices of vascular and metabolic health. Ninety young men were categorized into three groups: 1) overweight untrained (OU; n = 30; BMI 30.7 ± 2.1 kg/m2); 2) overweight trained [OT; n = 30; BMI 29.0 ± 1.9; ≥4 d/wk resistance training (RT)]; and 3) lean trained (LT; n = 30; BMI 23.7 ± 1.4; ≥4 d/wk RT). Using a novel assay on the basis of the HDL-mediated rate of oxidation of dihydrorhodamine (DOR), we determined the functional (redox) properties of HDL and examined correlations between DOR and indices of vascular and metabolic health in the cohort. DOR was significantly lower in both trained groups compared with the untrained group (LT, 1.04 ± 0.49; OT, 1.39 ± 0.57; OU, 1.80 ± 0.74; LT vs. OU P < 0.00001; OT vs. OU P = 0.02), however, DOR in the OT group was not significantly different from that of the LT group. DOR was negatively associated with HDL-cholesterol ( R = −0.64), relative strength ( R = −0.42), sex hormone-binding globulin ( R = −0.42), and testosterone ( R = −0.35) (all P ≤ 0.001); whereas DOR was positively associated with triglycerides ( R = 0.39, P = 0.002), oxidized low-density lipoprotein ( R = 0.32), body mass index ( R = 0.43), total mass ( R = 0.35), total fat mass ( R = 0.42), waist circumference ( R = 0.45), and trunk fat mass ( R = 0.42) (all P ≤ 0.001). Chronic RT is associated with improved HDL redox activity. This may contribute to the beneficial effects of RT on reducing cardiovascular disease risk, irrespective of body weight status.

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