scholarly journals Clipping aneurysms improves outcomes for patients undergoing coiling

2019 ◽  
Vol 130 (5) ◽  
pp. 1491-1497 ◽  
Author(s):  
Ian A. Anderson ◽  
Ahilan Kailaya-Vasan ◽  
Richard J. Nelson ◽  
Christos M. Tolias
Keyword(s):  
Endovascular Procedures ◽  
Aneurysmal Subarachnoid Hemorrhage ◽  
Statistical Significance ◽  
Mortality Rates ◽  
Endovascular Techniques ◽  
Data Set ◽  
Case Selection ◽  
The One ◽  
The Relationship ◽  
One Way Anova

OBJECTIVEMost intracranial aneurysms are now treated by endovascular rather than by microsurgical procedures. There is evidence to demonstrate superior outcomes for patients with aneurysmal subarachnoid hemorrhage (aSAH) treated by endovascular techniques. However, some cases continue to require microsurgery. The authors have examined the relationship between the number of aneurysms treated by microsurgery and outcome for patients undergoing treatment for aSAH at neurosurgical centers in England.METHODSThe Neurosurgical National Audit Programme (NNAP) database was used to identify aSAH cases and to provide associated 30-day mortality rates for each of the 24 neurosurgical centers in England. Data were compared for association by regression analysis using the Pearson product-moment correlation coefficient and any associations were tested for statistical significance using the one-way ANOVA test. The NNAP data were validated utilizing a second, independent registry: the British Neurovascular Group’s (BNVG) National Subarachnoid Haemorrhage Database.RESULTSIncreasing numbers of microsurgical cases in a center are associated with lower 30-day mortality rates for all patients treated for aSAH, irrespective of treatment modality (Pearson r = 0.42, p = 0.04), and for patients treated for aSAH by endovascular procedures (Pearson r = 0.42, p = 0.04). The correlations are stronger if all (elective and acute) microsurgical cases are compared with outcome. The BNVG data validated the NNAP data set for patients with aSAH.CONCLUSIONSThere is a statistically significant association between local microsurgical activity and center outcomes for patients with aSAH, even for patients treated endovascularly. The authors postulate that the number of microsurgical cases performed may be a surrogate indicator of closer neurosurgical involvement in the overall management of neurovascular patients and of optimal case selection.

scholarly journals Children with 5′-end NF1 gene mutations are more likely to have glioma

2017 ◽  
Vol 3 (5) ◽  
pp. e192 ◽  
Author(s):  
Corina Anastasaki ◽  
Stephanie M. Morris ◽  
Feng Gao ◽  
David H. Gutmann
Keyword(s):  
Gene Mutation ◽  
Statistical Significance ◽  
Gene Mutations ◽  
Neurofibromatosis Type ◽  
Published Data ◽  
Data Sets ◽  
Nonsense Mutations ◽  
Data Set ◽  
Nf1 Gene ◽  
The Relationship

Objective:To ascertain the relationship between the germline NF1 gene mutation and glioma development in patients with neurofibromatosis type 1 (NF1).Methods:The relationship between the type and location of the germline NF1 mutation and the presence of a glioma was analyzed in 37 participants with NF1 from one institution (Washington University School of Medicine [WUSM]) with a clinical diagnosis of NF1. Odds ratios (ORs) were calculated using both unadjusted and weighted analyses of this data set in combination with 4 previously published data sets.Results:While no statistical significance was observed between the location and type of the NF1 mutation and glioma in the WUSM cohort, power calculations revealed that a sample size of 307 participants would be required to determine the predictive value of the position or type of the NF1 gene mutation. Combining our data set with 4 previously published data sets (n = 310), children with glioma were found to be more likely to harbor 5′-end gene mutations (OR = 2; p = 0.006). Moreover, while not clinically predictive due to insufficient sensitivity and specificity, this association with glioma was stronger for participants with 5′-end truncating (OR = 2.32; p = 0.005) or 5′-end nonsense (OR = 3.93; p = 0.005) mutations relative to those without glioma.Conclusions:Individuals with NF1 and glioma are more likely to harbor nonsense mutations in the 5′ end of the NF1 gene, suggesting that the NF1 mutation may be one predictive factor for glioma in this at-risk population.

scholarly journals Psychological Capital Mediates the Association between Job Stress and Burnout of among Korean Psychiatric Nurses

Healthcare ◽  
2020 ◽  
Vol 8 (3) ◽  
pp. 199
Author(s):  
Sooyeong Kim ◽  
YoungRan Kweon
Keyword(s):  
Job Stress ◽  
Psychological Capital ◽  
Statistical Significance ◽  
Psychiatric Hospitals ◽  
Mediating Effect ◽  
Self Report ◽  
Psychiatric Nurses ◽  
Mediating Effects ◽  
The Relationship ◽  
One Way Anova

This study examined the mediating effect of psychological capital in the relationship between job stress and burnout of psychiatric nurses. The participants were 108 psychiatric nurses working in three psychiatric hospitals located in South Korea. Data were collected from 10 August to 15 September 2018 using self-report questionnaires. Data were analyzed using descriptive statistics, t-test, one-way ANOVA, Pearson’s correlation coefficient, and multiple linear regression by IBM SPSS 24.0 program. In addition, a bootstrapping test using the SPSS PROCESS macro was conducted to test the statistical significance of the mediating effect. There was significant correlation between job stress, psychological capital, and burnout. Psychological capital showed partial mediating effects in the relationship between job stress and burnout. Job stress explained 29.7% of the variance in burnout, and the model including job stress and psychological capital explained 49.6% of the variance in burnout. The bootstrapping showed that psychological capital was a significant sub-parameter and decreased job stress and burnout (LLCI = −0.1442, ULCI = −0.3548). These findings suggest that psychiatric nurses’ burnout can be reduced by implementing various health care programs designed to increase psychological capital.

scholarly journals Proximity to the Treating Centre and Outcomes Following Subarachnoid Hemorrhage

2011 ◽  
Vol 38 (1) ◽  
pp. 36-40 ◽  
Author(s):  
Cian J. O'Kelly ◽  
Julian Spears ◽  
David Urbach ◽  
M. Christopher Wallace
Keyword(s):  
Subarachnoid Hemorrhage ◽  
Critically Ill ◽  
Critically Ill Patients ◽  
Survival Benefit ◽  
Aneurysmal Subarachnoid Hemorrhage ◽  
Mortality Rates ◽  
Limited Resources ◽  
Early Complications ◽  
The Impact ◽  
The Relationship

Abstract:Background:In the management of subarachnoid hemorrhage (SAH), the potential for early complications and the centralization of limited resources often challenge the delivery of timely neurosurgical care. We sought to determine the impact of proximity to the accepting neurosurgical centre on outcomes following aneurysmal SAH.Methods:Using administrative data, we analyzed patients undergoing treatment for aneurysmal subarachnoid hemorrhage at neurosurgical centres in Ontario between 1995 and 2004. We compared mortality for patients receiving treatment at a centre in their county (in-county) versus those treated from outside counties (out-of-county). We also examined the impact of distance from the patient's residence to the treating centre.Results:The mortality rates were significantly lower for in-county versus out-of-county patients (23.5% vs. 27.6%, p=0.009). This advantage remained significant after adjusting for potential confounders (HR=0.84, p=0.01). The relationship between distance from the treating centre and mortality was biphasic. Under 300km, mortality increased with increasing distance. Over 300km, a survival benefit was observed.Conclusions:Proximity to the treating neurosurgical centre impacts survival after aneurysmal SAH. These results have significant implications for the triage of these critically ill patients.

scholarly journals COVID-19 hospital activity and in-hospital mortality during the first and second waves of the pandemic in England: an observational study

Thorax ◽  
2021 ◽  
pp. thoraxjnl-2021-218025
Author(s):  
William K Gray ◽  
Annakan V Navaratnam ◽  
Jamie Day ◽  
Julia Wendon ◽  
Tim W R Briggs
Keyword(s):  
Hospital Mortality ◽  
Hospital Stay ◽  
Ethnic Groups ◽  
Mortality Rates ◽  
Data Set ◽  
Black African ◽  
Substantial Decline ◽  
The Relationship ◽  
Second Wave

IntroductionWe aimed to examine the profile of, and outcomes for, all people hospitalised with COVID-19 across the first and second waves of the pandemic in England.MethodsThis was an exploratory retrospective analysis of observational data from the Hospital Episode Statistics data set for England. All patients aged ≥18 years in England with a diagnosis of COVID-19 who had a hospital stay that was completed between 1 March 2020 and 31 March 2021 were included. In-hospital mortality was the primary outcome of interest. The second wave was identified as starting on 1 September 2020. Multilevel logistic regression modelling was used to investigate the relationship between mortality and demographic, comorbidity and temporal covariates.ResultsOver the 13 months, 374 244 unique patients had a diagnosis of COVID-19 during a hospital stay, of whom 93 701 (25%) died in hospital. Adjusted mortality rates fell from 40%–50% in March 2020 to 11% in August 2020 before rising to 21% in January 2021 and declining steadily to March 2021. Improvements in mortality rates were less apparent in older and comorbid patients. Although mortality rates fell for all ethnic groups from the first to the second wave, declines were less pronounced for Bangladeshi, Indian, Pakistani, other Asian and black African ethnic groups.ConclusionsThere was a substantial decline in adjusted mortality rates during the early part of the first wave which was largely maintained during the second wave. The underlying reasons for consistently higher mortality risk in some ethnic groups merits further study.

scholarly journals Intensity of Soccer Players’ Training Load in Small-Sided Games with Different Number of Players

2020 ◽  
Vol 60 (1) ◽  
pp. 55-74
Author(s):  
Nikolas Nagy ◽  
Miroslav Holienka ◽  
Matej Babic ◽  
Jakub Michálek ◽  
Egon Kunzmann
Keyword(s):  
Heart Rate ◽  
Statistical Significance ◽  
Soccer Players ◽  
Special Software ◽  
Systematic Training ◽  
The Difference ◽  
The One ◽  
Post Hoc ◽  
Experimental Group ◽  
One Way Anova

SummaryThe main aim of this research was to compare differences in heart rate values (HR) of soccer players during small-sided games (SSGs) with different number of players. We assumed that the number of “neutral” player or players in small-sided games will significantly affect the intensity of SSGs and in this case the heart rate values of participating players. The experimental group consisted of older junior players from the FC DAC 1904 Dunajská Streda soccer club (n = 9). The heart rate values were evaluated on the basis of collected data, which we obtained using Polar sport testers and special software Polar Team2. In order to find out the statistical significance of the difference in heart rate was used the One-Way ANOVA and the Bonferroni post hoc test. The level of statistical significance we set at 5 %. We found out that with increasing number of “neutral” players’ the intensity of small-sided games gradually decreased. During SSG1 (3 vs. 3), we recorded the highest achieved average heart rate values of the monitored players, in average 171.33 ± 9.39 beats.min-1. This form of the SSGs was the most intense, but not statistically significant. Our recommendation is to employ SSGs in the systematic training process with different number of players, because we can adequately prepare the players for the match load itself. Attention need to be paid for the playing position requirements.

scholarly journals Employment Adjustments on the Internal and External Labour Market – An Empirical Study with Personnel Records of a German Company

2009 ◽  
Vol 229 (2-3) ◽  
Author(s):  
Knut Gerlach ◽  
Olaf Hübler
Keyword(s):  
Descriptive Statistics ◽  
Data Set ◽  
Job Change ◽  
Product Demand ◽  
Employment Adjustment ◽  
Innovative Products ◽  
The One ◽  
The Relationship ◽  
The Empirical Analysis

SummaryFirms are affected by the product demand. This leads to employment adjustments. In the literature we find only very few contributions investigating the issue whether internal adjustments are linked and which relationships exist with external adjustments. Are they of a complementary or substitutive nature? Furthermore, it is of interest to find out, whether we can observe an obvious trend and whether the adjustments are driven by cyclical movements.For this study we have an extensive data set of a large German manufacturing company, which supplies innovative products for the domestic and international market, provided on amonthly base from January 1999 to December 2005. The empirical analysis starts with descriptive statistics. We find that the employment adjustment cycle coincides only to a certain degree with the macroeconomic cycle. Internal and external adjustments are more characterized by complementarity than by substitution. Over the observed period we cannot detect analogous wage adjustments. It is noticeable that in 2003 compared with the years before the number of employees is substantially reduced. The econometric investigation is based on a two-stage approach. We start with a bivariate probit estimation in order to extract the relationship between the probability of overtime and of promotion. Unobserved variables have opposite effects on the former and the latter adjustment instrument. Furthermore, we detect a negative trend of internal employment adjustments. Cyclical effects are ambiguous. The next step, the determination of external adjustments with respect to overtime and promotion adjustments, is split into two estimates. On the one hand we do not distinguish between the type of external employment adjustment and on the other hand we use this information separating between quits, layoffs, workers with a cancellation agreement and with a transition into a transfer organisation. The first approach demonstrates that a promotion reduces the probability to leave the firm while overtime is positively associated with an external job change. This pattern holds generally speaking in the second, more detailed estimates. Quits are the exception. In this case we observe opposite effects. Finally, we cannot detect any influences of promotions on cancellation agreements.

scholarly journals The Effect of Students’ Perceptions on Civic Education Learning on the Mastery of Concepts

2020 ◽  
Vol 3 (1) ◽  
pp. 104-111
Author(s):  
Ratnaningsih Ratnaningsih ◽  
Rini Triastuti ◽  
Dewi Gunawati
Keyword(s):  
Civic Education ◽  
Validity And Reliability ◽  
Millennial Students ◽  
Civic Learning ◽  
The One ◽  
Initial Perception ◽  
Relationship Of ◽  
Quality Learning ◽  
The Relationship ◽  
One Way Anova

Nowadays, quality learning from teachers is an important factor in preparing graduates who are able to compete competitively. The relationship of the millennial students and technology transforms the way they get to know the world. Therefore, achievement, guidance and motivation for the current generation is a challenge. Students' perceptions are directly related to self-concept, motivation, effort, and help in finding behaviors. A perception is one’s response resulting from a stimulus received. Students’ learning processes cannot be separated from perceptions as a process of understanding information. Teachers must be able to develop a strategy that ensures learning conducted by teachers is in accordance with what the students expect and desire.  A good student's initial perception of the material being studied makes students enthusiastic in participating in learning.  A good perception of the object will affect motivation and desire to learn, which will affect the students’ mastery of concepts. Students’ perceptions can contribute to their mastery of concepts in civic learning. This research aims to determine the significant effect of students' perceptions of learning civics on their mastery of concepts. The research was conducted on 64 students. The instrument was tested for validity and reliability. The data were then analyzed using the One-Way Anova test. The results showed students' perceptions of civic education learning significantly influences their mastery of concepts.

scholarly journals The relationship between the nomophobic levels of higher education students in Ghana and academic achievement

PLoS ONE ◽  
2021 ◽  
Vol 16 (6) ◽  
pp. e0252880
Author(s):  
Harry Barton Essel ◽  
Dimitrios Vlachopoulos ◽  
Akosua Tachie-Menson
Keyword(s):  
Higher Education ◽  
Academic Achievement ◽  
University Students ◽  
Statistical Significance ◽  
Cross Sectional Study ◽  
Education Students ◽  
Cross Sectional ◽  
The Relationship ◽  
One Way Anova

There is an upsurge in the use of mobile phones among higher education students in Ghana, which may result in the nomophobia prevalence with the students. Therefore, the need to assess the influence of nomophobia within the student population in Ghana. This descriptive cross-sectional study investigated the prevalence of nomophobia and the sociodemographic variables, and the association with academic achievement of the understudied population. A self-reporting nomophobia questionnaire, composed of 20 dimensions, was answered by 670 university students to measure the nomophobia prevalence. Raw data were estimated using descriptive statistics, and one-way ANOVA and Independent T-test. While the findings showed diverse grades of nomophobia, statistical significance between academic achievement and the level of nomophobia was observed. This study concludes that there is a high nomophobia prevalence among university students in Ghana as the use of smartphones increases. However, follow-up studies should be conducted in Ghanaian universities to monitor nomophobia and its associates in order to reduce the adverse effects of habitual use of smartphones.

Exploring students digital activities and performances through their activities logged in learning management system using educational data mining approach

2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Adel Bessadok ◽  
Ehab Abouzinadah ◽  
Osama Rabie
Keyword(s):  
Data Mining ◽  
Academic Performance ◽  
Management System ◽  
Learning Management System ◽  
Statistical Significance ◽  
Educational Data Mining ◽  
Data Set ◽  
Content Type ◽  
Learning Management ◽  
The Relationship

Purpose This paper aims to investigate the relationship between the students’ digital activities and their academic performance through two stages. In the first stage, students’ digital activities were studied and clustered based on the attributes of their activity log of learning management system (LMS) data set. In the second stage, the significance of the relationship between these profiles and the associated academic performance was tested statistically. Design/methodology/approach The LMS delivers E-learning courses and keeps track of the students’ activities. Investigating these students’ digital activities became a real challenge. The diversity of students’ involvement in the learning process was proven through the LMS which characterize students’ specific profiles. The Educational Data Mining (EDM) approach was used to discover students’ learning profiles and associated academic performances, where the activity log file exemplified their activities hosted in the LMS. The sample study data is from an undergraduate e-course hosted on the platform of Blackboard LMS offered at a Saudi University during the first semester of the 2019–2020 academic year. The chosen undergraduate course had 25 sections, and the students attending came from science, technology, engineering and math background. Findings Results show three clusters based on the digital activities of the students. The correlation test shows the statistical significance and proves the effect of the student’s profile on his academic performance. The data analysis shows that students with different profiles can still get similar academic performance using LMS. Originality/value This empirical study emphasizes the importance of the EDM approach using clustering techniques which can help the instructor understand how students use the provided LMS content to learn and then can deliver them the best educational experience.

scholarly journals Meshness of sewer networks and its implications for flooding occurrence

2020 ◽  
Vol 81 (1) ◽  
pp. 40-51 ◽  
Author(s):  
Julian David Reyes-Silva ◽  
Björn Helm ◽  
Peter Krebs
Keyword(s):  
The Other ◽  
Urban Drainage ◽  
Sewer System ◽  
Data Set ◽  
Drainage Networks ◽  
Study Case ◽  
The One ◽  
Flooding Events ◽  
The Relationship ◽  
Sewer Networks

Abstract Understanding the factors that affect the occurrence of failures in urban drainage networks (UDNs) is a key concept for developing strategies to improve the reliability of such systems. Although a lot of research has been done in this field, the relationship between UDN structure (i.e. layout) and its functional failures is still unclear. In this context, the present study focuses first on determining which are the most common sewer layout topologies, based on a data set of 118 UDNs, and then on analyzing the relationship between these and the occurrence of node flooding using eight subnetworks of the sewer system of Dresden, Germany, as a study case. A method to ‘quantify’ the topology of a UDN in terms of similarity to a branched or meshed system, referred to as Meshness, is introduced. Results indicate, on the one hand, that most networks have branched or predominantly branched topologies. On the other hand, node flooding events in networks with higher Meshness values are less likely to occur, and have shorter durations and smaller volumes than in predominantly branched systems. Predominantly meshed systems are identified then as more reliable in terms of flooded nodes and flooding volumes.

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