scholarly journals Clinical Profile, Dyslipidemia and ACS - a Correlation

1970 ◽  
Vol 52 (195) ◽  
pp. 907-913
Author(s):  
Bikash Dali

Introduction: To analyze lipid profile in patients with ACS, and to study the pattern of the involvement and complication in ACS.  Methods: Hundred and eight consecutive cases of ACS, attending the CCU of Tribhuvan University Teaching Hospital fulfilling the criteria, were taken for the present study. Patient from age 30 and older were studied. All cases were scrutinized to detail serial 12 lead EKG, serial cardiac biochemical markers, laboratory test, echocardiographic study. Design of the study was carried out in prospective, cross sectional study. Results: Hyperlipidemia was present in 61% of the patients. Only 27% of them were on statins. Most of them had high cholesterol level 68%, high Tgl level 75%, Ldl 50%, where as <40 Hdl (93%) patient were found to be low. 40% was found to have UAP. In addition patient with hypertension (76%) diabetes (65%) also had comorbidity for obesity 35%, and lipid abnormalities 75% for triglycerides, 66% for TC, 50% for LDL-C, 93% for low HDL-C, and a family history of CAD in 57%.  Conclusions: The outcome of this study showed that the majority are male, relatively younger as compared to Western population. USA and STEMI were the dominant types of ACS. Strong correlations between TC, LDL-C, and low HDL-C in patient with ACS were noted. Majority of patients had hypertension, IHD in their families and Hyperlipidemia diabetes, smoking as the major risk factors. Better control of risk factors and the awareness of preventive strategies are needed. 


2017 ◽  
Vol 2017 ◽  
pp. 1-5 ◽  
Author(s):  
Vicky Jocelyne Ama Moor ◽  
Sylvie Ndongo Amougou ◽  
Sebastien Ombotto ◽  
Felicien Ntone ◽  
Doriane Edna Wouamba ◽  
...  

Objective. To determine the frequency of lipid abnormalities in patients with a cardiovascular risk and disease at the University Teaching Hospital (UTH) of Yaoundé.Materials and Methods. We conducted a cross-sectional study from 1 March to 31 May 2015 at the UTH of Yaoundé. We included all patients seen in the outpatient department with a diagnosis of a cardiovascular disease or a risk factor for cardiovascular disease. Patients who accepted to participate in the study were asked to answer a questionnaire; after that a blood sample was taken for lipid profile. An informed consent was signed by all the participants and the study has received approval from the national ethic committee.Results. We recruited 264 patients of which 119 were men and 145 were women with a sex ratio of 0.82. Mean age was 61.36 years. The frequency of lipid profiles abnormalities was as follows: low HDL cholesterol (44.3%), hypertriglyceridemia (18.9%), high LDL cholesterol (3.8%), and high total cholesterol 3.4%). Hypertriglyceridemia was strongly associated with type 2 diabetes mellitus.Conclusion. Low levels of HDL cholesterol and hypertriglyceridemia are more prevalent in our study population. More studies are needed to confirm this finding in our environment.



2018 ◽  
Vol 75 (8) ◽  
pp. 764-772
Author(s):  
Suncica Ivanovic ◽  
Sanja Trgovcevic

Background/Aim. After a fall, the elderly can develop a fear of falling which can be more frequent and more serious problem than the fall itself because it represents the main factor limiting an older person in his/her everyday functioning. The aim of this study was to identify and examine, in a more detailed way, risk factors for developing fear of falling triggered by the history of their falls over the previous year in the elderly in Serbia who live in houses or apartments. Methods. The cross-sectional study was conducted on 400 people, mean age 75.04 years (min. 65, max. 94), randomly selected from the register of patients in the Primary Health Center of Nis (164 men and 236 women), in the period January- June 2014. Socio-demographic questionnaire ? Elderly Fall Screening Test (EFST), Multi-Factor Questionnaire Falls (MFQ) and Falls Efficacy Scale International (FESI) were used in this study. Results. After applying the multivariate binary logistic regression, it was found that significant predictors for developing fear of falling were as follows: female gender (OR = 2.599; p = 0.009), age 75?79 years (OR = 4.637; p = 0.009) and over 80 years (OR = 3.830; p = 0.001), increase in household members (OR = 1.206; p = 0.033), people who estimate their health as average (OR = 0.268; p < 0.001) and good (OR = 0.059; p < 0.001), number of falls higher than 2 (OR = 2.761; p = 0.003), presence of injuries during the fall (OR = 2.483; p = 0.028), periodical and repeating situations of ?near-fall? (OR = 3.830; p = 0.001), limited activity (OR = 2.124; p = 0.007) problems with sight (OR = 3.006; p < 0.001), cognitive problems (OR = 2.296; p = 0.005) and problems with balance (OR = 3.809; p < 0.001). Conclusion. The results of this study can be used for planning promotional programs for falls and a fear of falling prevention, as well as prevention of their consequences.



2020 ◽  
Vol 5 (1) ◽  

Introduction: The single most important risk factor for post-partum maternal infection is Cesarean section (C/S) with a 5-20-fold greater risk for infection compared to a vaginal delivery. Post Cesarean wound infection is diagnosed in 2.5 to 16 percent of patients. Early wound infections (in the first 24 to 48 hours) are usually due to group A or B beta-hemolytic streptococcus and are characterized by high fever and cellulitis while later infections are likely due to Staphylococcus epidermises or aureus, Escherichia coli, or Proteus species. Objectives: To determine the prevalence, risk factors and bacterial profile of wound sepsis following Cesarean at Mbarara Regional Referral Hospital (MRRH). Methods: A cross sectional study of mothers who delivered by Cesarean at MRRH was conducted. Mothers were recruited consecutively until the sample size was achieved. The main dependent variable was wound sepsis confirmed by a positive culture for microorganisms. Results: Of the 359 mothers recruited in the study, 54 (15.5%) developed Cesarean wound sepsis. The risk factors associated with post Cesarean wound sepsis were severe anemia, lack of preoperative antibiotics use, poor antenatal attendance, mothers referred from peripheral health facilities, abnormal Body Mass Index (BMI), diabetes mellitus, more than five vaginal examinations, prolonged rupture of membranes before C/S, and prolonged labour. Staphylococcus aureus was isolated in 48.2% of all the septic cases and most of the bacterial isolates were susceptible to ceftriaxone, ceftazidime, ciprofloxacin and nalidixic acid and resistant to penicillin. Conclusion: The prevalence of post Cesarean wound sepsis is high with staphylococcus aureus being the most common bacteria isolated in infected wounds. Most of the bacteria were susceptible to third generation cephalosporins and quinolones. Antibiotics use was protective against developing wound sepsis.



2020 ◽  
Author(s):  
yinxia su ◽  
Wenli Li ◽  
Yaoqin Lu ◽  
Mingyue Xue ◽  
Muyaseer Haireti ◽  
...  

Abstract Background The prevalence of metabolic syndrome (MetS) of comprehensive population are always lower than mono- population. However, studies on MetS and its components of it and its subgroups (different ages, genders, races, regions) based on big data and using a same diagnosis criterion are rare. Method: A total of 9,745,640 Chinese adults aged ≥ 18 years in Xinjiang,the largest autonomous region of Multi-ethnic, were enrolled in the study. MetS was defined by modified Adults Treatment Panel (ATP III) criteria.Prevalence of metabolic syndrome and its components were calculated. To further explore the correlates of MetS and its components logistic regression were used. Results The overall prevalence of MetS was 20.85% [Sex: 20.06% in female, 21.56% in man; Age: 39.22% in 60 year older followed by 40–59 year 26.32% and 18–39 years 9.56%; Ethnicity: 28.19% in Hui followed by Han (26.39%), Uyghur(18.56%), Other(18.61%), Kazak(17.98%), Mongolian (17.87%), Kyrgyz(14.44%)], living in city and town (23.03%) or north(24.78%) had higher prevalence of MetS than living in rural (19.94%) and South (17.66%). Although the prevalence of hypertension, smoking, drinking and lack of physical activity in Kyrgyz, Mongolian and Kazakh were higher than those of other ethnic groups, the risk of MetS was lower than that of other. The results also showed that although their risk of central obesity and hypertension was higher than that of Han, Hui, Uygur and other, the risk of high-TG, low HDL-C and Elevated-FPG was significantly lower than that of other ethnic groups. Among them, the Mongolian had the lowest risk of high-TG and low-HDL-C, while the Kazakh had the lowest risk of elevated-FPG. In addition, except that the risk of central obesity in males was lower than that in females, the other components of males were higher than those in females, but the risk of MetS was lower than that in females. The risk of MetS and its components in the elderly was significantly higher than that in the young, and physical activity did not show reduce the risk of MetS in the general population. Conclusion The reason why the prevalence of MetS in the comprehensive population is lower than that in most mono-population may be that some subgroups of the population have the ability to resist risk factors in terms of genetic structure such as Kyrgyz, Mongolian, Kazak, and the influence in this aspect may exceed that of lifestyle. Within each subgroup, the prevalence of MetS is still increasing. Central obesity is an important risk factor for women with MetS. Elevated-FPG and high-TG are the most important risk factors of MetS in Han, Hui. Climate and lifestyle are the main causes of MetS in northern Xinjiang and city and town residents.



PLoS ONE ◽  
2021 ◽  
Vol 16 (8) ◽  
pp. e0254590
Author(s):  
Qiqi Shi ◽  
Ran Wang ◽  
Huifeng Zhang ◽  
Yaping Shan ◽  
Ming Ye ◽  
...  

SUA is associated with cardiovascular disease and cardiovascular disease risk factors in adults, including chronic kidney disease, coronary artery disease, stroke, diabetes mellitus, preeclampsia, and hypertension. A cross-sectional study was carried out among 11219 adolescents 12 to 18 years of age examined in the 2001–2018 National health and Nutrition Examination Survey. We examined the association between SUA and CVD risk factors. The overall mean SUA level was 5.00±1.24mg/dl. Restricted cubic spline analysis results revealed SUA was inversely associated with HDL-C and SPISE and positively associated with TC, TG, LDL-C, nonHDL-C, insulin, SBP and DBP after full adjustment. Multiple logistic analyses showed SUA level was independently associated with high TC, high TG, high nonHDL-C and low HDL-C (all p<0.05). Furthermore, females in the highest quartile of SUA had significantly higher odds for elevated BP (OR = 2.38, 95%CI:1.02–5.54, P<0.05) and high TC (OR = 2.22, 95%CI: 1.49–3.30, P<0.001), which not observed in males. Increased levels of SUA were associated with increased odds of various cardiovascular risk factors in American adolescents, especially females.



2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
Amir Houshang Mehrparvar ◽  
Seyyed Jalil Mirmohammadi ◽  
Mehrdad Mostaghaci ◽  
Maryam Bahaloo ◽  
Mohammad Heydari ◽  
...  

Introduction. Cardiovascular disorders (CVDs) are among the most important diseases in the world and determination of their risk factors is essential for primary and secondary prevention. This study aimed to evaluate these risk factors in workers of tile and ceramic industry, a main industry in Yazd. Materials and Methods. In a cross-sectional study, 1075 tile and ceramic workers were selected by simple sampling method. BMI, blood pressure, FBS, and lipid profile were measured and compared to international standards. Results. 731 individuals (68%) had at least one risk factor, and 52%, 12%, 3%, and 0.7% had one, two, three, and four risk factors, respectively. The most common risk factor was abnormal BMI (49.6%); low HDL (48.4%) and high TG (14.1%) were in the second and third orders. Conclusion. This study showed a relatively high prevalence for CVD risk factors among tile and ceramic workers. Low HDL, high TG, and overweight were the most frequent risk factors in this population.



2020 ◽  
Vol 18 (1) ◽  
pp. 10-15
Author(s):  
Stepan Feduniw ◽  
◽  
Olga Płaza ◽  
Dominika Paździor ◽  
Katarzyna Kosińska-Kaczyńska ◽  
...  

Introduction. It was established that intragestational depression is a common disease, with the estimated average prevalence of 10–25% in all expectant mothers worldwide. Aim of the study. The aim of the study was to evaluate the frequency of depressive symptoms in pregnant women in Poland and to identify which factors may be related to a higher risk of depressive symptoms during pregnancy. Material and methods. A prospective cross-sectional study was performed. Depressive symptoms were assessed with the validated Edinburgh Postnatal Depression Scale (EPDS). 346 women were enrolled in the study. Results. 130 women (37.6%) scored 13 or more points and were considered as presenting with depressive symptoms. Independent risk factors of depressive symptoms during pregnancy including mood disorders diagnosed before the current pregnancy (aOR=2.68, 95%CI 1.37-5.22), mental disorders confirmed in family members (aOR=2.72, 95%CI 1.24-5.98), unhappiness in their current relationship (aOR=4.0, 95%CI 1.77-9.01), lack of support from family members (aOR=2.73, 95%CI 1.51-4.96) increased the risk of DS and good financial status decreased the risk of DS occurrence (aOR=0.45, 95%CI: 0.25-0.80). Conclusions. Pregnant women commonly report depressive symptoms. The evaluation of relations with the family members, socio-economic status, former depressive symptoms and possible prenatal depression are essential for proper screening of depression in pregnant women.



2021 ◽  
Vol 4 (1) ◽  
pp. 1-7
Author(s):  
Amenu Tolera Wirtu ◽  

Neuromusculoskeletal functions interplay in maintaining normal gait patterns. Changes in foot posture and architecture are results of diseases. For Instance, diabetes impacts human biomechanics of running and weight bearing of the foot. We conducted a prospective cross sectional study to assess the risk factors of anatomical foot changes in patients with Type-2 diabetes mellitus. It was carried out in normal 196 subjects at Mizan-Tepi University teaching hospital, Bench-Sheko zone, South-West, Ethiopia. Data were collected using a well-structured questionnaires and diabetic foot assessment checklists. Data analysis was done using SPSS, version 24. Whereas, randomly selected associated risk factors were assessed using multivariate linear regression model. Our results



2018 ◽  
Vol 13 (2) ◽  
Author(s):  
FM Akinlusi ◽  
TA Ottun ◽  
YA Oshodi

Aims: To determine the prevalence of urinary incontinence (UI); risk factors; impact on quality of life and symptom specific health seeking behaviour. Methods: A cross-sectional study of 395 women attending gynaecological clinic of the Lagos State University Teaching Hospital. UI was defined as the complaint of any involuntary leakage of urine in the previous six months. Socio-demographic characteristics, obstetrics, gynaecological, medical and surgical risk factors, impact on daily activities and treatment history were assessed. Univariate, bivariate and multivariable analyses were performed. Results: Participants age ranged from 25-67 years with a mean of 38.81 ± 10.1. Prevalence of UI was 32.9%.  Urge UI occurred in 18.0% of all respondents while the prevalence of stress and mixed incontinence was 7.3% and 7.6% respectively. Independent risk factors for urinary incontinence were age (OR= 0.49, 95%;CI = 0.26-0.92), higher body mass index (OR = 1.92; 95% CI =1.53-3.00) and history of constipation(OR = 2.11; 95% CI =1.30 - 3.43). About47%of those with UI admitted to having negative feelings such as despair, anxiety and depression while 45% had a cumulative moderate to severe affectation of their quality of life in all domains. Despite these, only 27.7% sought help. Conclusions: Despite thesubstantial impact of UI on the quality of life, majority do not seek help. Addressing modifiable risks factors, improving treatment seeking behaviour by correction of misconceptions and elimination of stigma will go a long way in reducing the prevalence of UI.



Author(s):  
Pedro López Rodríguez

Introduction: Vaginal discharge syndrome is an infectious process of the vagina with a florid symptomatology and psychosocial impact on the female population. Objective: To characterize the patients of childbearing age with vaginal discharge syndrome in the Basic Working Group number 2 of the Párraga polyclinic between January and December 2018. Method: Observational, descriptive, and cross-sectional study. 195 patients of childbearing age (between 15 and 49 years of age) of the medical office 10 were studied in the period from January to December 2018 who attended the medical consultation referring to presenting vaginal discharge and / or associated symptoms performing anamnesis, physical examination, and microbiological study. Results: 32.8% were between 25 and 29 years old and 41.7% wereblack. At least half were 52.3% pre-university; more than 59.0% were workers. The majority began sexual intercourse before the age of 20. 90.3% presented risk factors associated with vaginal discharge. The white, lumpy caseous flow represented 63.1%. At least 9 out of 10 patients presented vaginitis. More than 75% had Monilia or Gardnerellavaginalis. It was found that 95% of patients with vaginitis had risk factors. Conclusions: Patients predominated between the second and third decade of life, of the black race, with the pre-university concluded and workers. The majority were single or accompanied, had begun their sexual life at an early age and presented risk factors. Patients with vaginitis prevailed, with white, lumpy, case-like discharge and with Moniliaasthe germ causing vaginal discharge. There was a statistically significant relationship between the presence of risk factors and the flow classification.



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