scholarly journals Dyslipidemia in Patients with a Cardiovascular Risk and Disease at the University Teaching Hospital of Yaoundé, Cameroon

2017 ◽  
Vol 2017 ◽  
pp. 1-5 ◽  
Author(s):  
Vicky Jocelyne Ama Moor ◽  
Sylvie Ndongo Amougou ◽  
Sebastien Ombotto ◽  
Felicien Ntone ◽  
Doriane Edna Wouamba ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Cardiovascular Risk ◽  
Teaching Hospital ◽  
Hdl Cholesterol ◽  
Cross Sectional Study ◽  
University Teaching ◽  
Cross Sectional ◽  
Low Hdl ◽  
The University ◽  
Lipid Abnormalities

Objective. To determine the frequency of lipid abnormalities in patients with a cardiovascular risk and disease at the University Teaching Hospital (UTH) of Yaoundé.Materials and Methods. We conducted a cross-sectional study from 1 March to 31 May 2015 at the UTH of Yaoundé. We included all patients seen in the outpatient department with a diagnosis of a cardiovascular disease or a risk factor for cardiovascular disease. Patients who accepted to participate in the study were asked to answer a questionnaire; after that a blood sample was taken for lipid profile. An informed consent was signed by all the participants and the study has received approval from the national ethic committee.Results. We recruited 264 patients of which 119 were men and 145 were women with a sex ratio of 0.82. Mean age was 61.36 years. The frequency of lipid profiles abnormalities was as follows: low HDL cholesterol (44.3%), hypertriglyceridemia (18.9%), high LDL cholesterol (3.8%), and high total cholesterol 3.4%). Hypertriglyceridemia was strongly associated with type 2 diabetes mellitus.Conclusion. Low levels of HDL cholesterol and hypertriglyceridemia are more prevalent in our study population. More studies are needed to confirm this finding in our environment.

scholarly journals Profil Évolutif Des Accidents Vasculaires Cérébraux Hémorragiques À Yaoundé (Hôpital Général& Centre Hospitalier Et Universitaire)

2016 ◽  
Vol 12 (21) ◽  
pp. 197
Author(s):  
Patrice Emmanuel Awono Ateba ◽  
Justin Ndié ◽  
Julienne Louise Ngo Likeng ◽  
Benjamin Alexandre Nkoum
Keyword(s):  
General Hospital ◽  
Teaching Hospital ◽  
Public Health Problem ◽  
Premature Mortality ◽  
Cross Sectional Study ◽  
University Teaching ◽  
Evolutionary Trend ◽  
Cross Sectional ◽  
Duration Of Hospitalization ◽  
The University

Nowadays, strokes constitute a real public health problem in the world. In Cameroon, because of the people’s lifestyle potential risk factor, the prevalence of hemorrhagic strokes as well as its mortality is on the rise. This study was aimed at analyzing the evolutionary profile of hemorrhagic strokes at the General Hospital and the University Teaching Hospital in Yaoundé. A retrospective cross-sectional study with a qualitative component was carried out at the General Hospital and the University Teaching Hospital in Yaoundé for 2 months. Were included, all patients with a diagnosis of hemorrhagic strokes confirmed by CT Scan. With the help of a scale, patient data over a 30 month’s period (2013-2015) were collected. Over 1037 patients hospitalized in intensive care unit at the General Hospital and the University Teaching Hospital in Yaoundé, 122 cases of hemorrhagic strokes were diagnosed, that is a prevalence of 11.8%. The average age was 58±10.52 and the most vulnerable age range was between 50 and 70 years with 67.2%. Men were most affected (60.7%) with a sex ratio of 1.54(74 men/48 women). Among these cases of hemorrhagic strokes still hospitalized, 70 had died giving a lethality rate of 57.4%. Only the duration of hospitalization had an effect on the outcome of patients with hemorrhagic strokes. Actually the patients, victims of hemorrhagic strokes who had had less than 21 days of hospitalization, had 2.91 chances of dying as compared to those patients hospitalized for over 21 days (OR=2.91 IC 95% [5.1-65.7]; p=0.000). The late admission to reanimation, the difficulties encountered by victims of hemorrhagic strokes and their careers, to handle the enormous cost of their treatment and the insufficiencies of the technical platform, were factors also influencing the evolution of hemorrhagic strokes hospitalized in reanimation at the General Hospital and the University Teaching Hospital in Yaoundé. Despite certain efforts aimed at reducing premature mortality, the prevalence of hemorrhagic strokes was increasing in reanimation at the General Hospital and University Teaching Hospital in Yaoundé. Only multisectorial actions of sensitization, the restructuring and amelioration of the care of this ailment will help reverse the evolutionary trend.

scholarly journals COVID-19 Disease in the Paediatric Population: A Cross Sectional Study at the University Teaching Hospital in Port Harcourt, Southern Nigeria

2021 ◽  
pp. 15-20
Author(s):  
L. E. Yaguo-Ide ◽  
G. K. Eke
Keyword(s):  
Teaching Hospital ◽  
Cross Sectional Study ◽  
University Teaching ◽  
Causative Organism ◽  
Sectional Study ◽  
Cross Sectional ◽  
Female Ratio ◽  
Corona Virus ◽  
Port Harcourt ◽  
The University

Background: Globally, there has been a destruction of human lives, economies and health systems by the novel corona virus pandemic. Presently there is no known certain cure, although a number of vaccines have been proposed to prevent the corona virus disease 2019 (COVID-19) which was first seen as increasing number of pneumonia cases in Wuhan, China, with severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) as the causative organism. Objectives: To screen paediatric patients for COVID-19 at the University of Port Harcourt Teaching Hospital and to know their pattern of presentation. Materials and Methods: Descriptive cross-sectional study, not controlled, over a period of six weeks, using interviewer administered structured questionnaire which was adapted and used at the Accident and Emergency Department for patients triaging as a COVID-19 Risk assessment tool. No action was required for a score of 0-7, while admission into COVID-19 holding area following review by IDU was recommended for a score 8 ≥17. All children brought into the department, requiring treatment were screened. Results: There were 131 patients, 74 (56.5%) males and 56 (42.7%) females, with a mean age 7.2 ± 5.41 years. Male: Female ratio was 1.3:1. Four children (3%) had a total score of ≥ 8, while half of them (n=2; 50%) tested positive for COVID-19, giving a disease prevalence of 1.5%. Both cases were females; fever and difficulty in breathing were the commonest symptoms. No mortality was recorded. Conclusions: COVID-19 prevalence is low in children, and they have a good outcome. A community-based study is recommended.

scholarly journals Vitamin D Deficiency Associated With Markers of Cardiovascular Disease in Children With Obesity

2018 ◽  
Vol 5 ◽  
pp. 2333794X1775177 ◽  
Author(s):  
Marisa Censani ◽  
Hoda T. Hammad ◽  
Paul J. Christos ◽  
Tiffany Schumaker
Keyword(s):  
Cardiovascular Disease ◽  
Vitamin D ◽  
Cardiovascular Risk ◽  
Vitamin D Deficiency ◽  
Density Lipoprotein ◽  
Hdl Cholesterol ◽  
Cross Sectional Study ◽  
Pediatric Endocrinology ◽  
Cross Sectional ◽  
Lipid Parameters

Adult studies have reported associations of low 25-hydroxyvitamin D (25OHD) with dyslipidemia and cardiovascular disease; however, there are scarce pediatric data regarding relationships between vitamin D status and specific lipid markers affecting cardiovascular risk. In this cross-sectional study of children evaluated at university-based pediatric endocrinology clinics, 178 patients meeting criteria for overweight or obesity had 25OHD levels assessed over a 2-year period; 60 of 178 had non-HDL (high-density lipoprotein) cholesterol and fasting lipid parameters performed. Patients with 25OHD <20 ng/mL had significantly higher non-HDL cholesterol (134.76 ± 47.32 vs 108.85 ± 31.14, P < .03), triglyceride (TG)/HDL ratio (3.09 ± 2.26 vs 1.82 ± 1.18, P = .03), total cholesterol (TC)/HDL ratio (4.23 ± 1.23 vs 3.40 ± 1.05, P < .01), TC (184.15 ± 40.19 vs 158.89 ± 30.10, P < .01), and TG (134.76 ± 47.32 vs 78.93 ± 37.46, P < .03) compared with 25OHD ≥20 ng/mL. Vitamin D deficiency was significantly associated with increase in atherogenic lipids and markers of early cardiovascular disease. These findings suggest that vitamin D deficiency may have negative effects on lipid parameters with increase in cardiovascular risk.

scholarly journals Clinical Profile, Dyslipidemia and ACS - a Correlation

1970 ◽  
Vol 52 (195) ◽  
pp. 907-913
Author(s):  
Bikash Dali
Keyword(s):  
Risk Factors ◽  
Cross Sectional Study ◽  
University Teaching ◽  
Study Patient ◽  
Cross Sectional ◽  
High Cholesterol Level ◽  
Echocardiographic Study ◽  
Study Results ◽  
Low Hdl ◽  
Lipid Abnormalities

Introduction: To analyze lipid profile in patients with ACS, and to study the pattern of the involvement and complication in ACS.  Methods: Hundred and eight consecutive cases of ACS, attending the CCU of Tribhuvan University Teaching Hospital fulfilling the criteria, were taken for the present study. Patient from age 30 and older were studied. All cases were scrutinized to detail serial 12 lead EKG, serial cardiac biochemical markers, laboratory test, echocardiographic study. Design of the study was carried out in prospective, cross sectional study. Results: Hyperlipidemia was present in 61% of the patients. Only 27% of them were on statins. Most of them had high cholesterol level 68%, high Tgl level 75%, Ldl 50%, where as <40 Hdl (93%) patient were found to be low. 40% was found to have UAP. In addition patient with hypertension (76%) diabetes (65%) also had comorbidity for obesity 35%, and lipid abnormalities 75% for triglycerides, 66% for TC, 50% for LDL-C, 93% for low HDL-C, and a family history of CAD in 57%.  Conclusions: The outcome of this study showed that the majority are male, relatively younger as compared to Western population. USA and STEMI were the dominant types of ACS. Strong correlations between TC, LDL-C, and low HDL-C in patient with ACS were noted. Majority of patients had hypertension, IHD in their families and Hyperlipidemia diabetes, smoking as the major risk factors. Better control of risk factors and the awareness of preventive strategies are needed. 

scholarly journals Status of Serum Lipids in Individuals with Depression

2016 ◽  
Vol 2 (1) ◽  
pp. 24-27 ◽  
Author(s):  
Saroj Sharma ◽  
Lilee Shrestha ◽  
Saroj Prasad Ojha ◽  
Bharat Jha
Keyword(s):  
Cardiovascular Disease ◽  
Lipid Profile ◽  
Serum Lipid ◽  
Test Group ◽  
Hdl Cholesterol ◽  
Cross Sectional Study ◽  
Depressive Illness ◽  
University Teaching ◽  
Cross Sectional ◽  
And Control

BACKGROUNDEpidemiological studies have shown the association between depressive illness with cardiovascular disease (CVD).  Serum lipid abnormality is one of the major risk factor for cardiovascular disease. Therefore, this study aimed to access the status of Serum lipid in individuals with depression.METHODSA cross sectional study was carried out in Tribhuvan University Teaching Hospital (TUTH) over the period of 16 month from June 2011 to October 2012. A total of 85 individuals with depression and the same number of age-sex matched controls were enrolled in the study.  Depression was diagnosed by Consultant Psychiatrist as per ICD-10-DCR criteria. Serum Lipid profile was assessed from both test and control groups after an overnight fasting. A written consent was taken for anthropometric data and sample collection.RESULTSLarge numbers of depressive individuals were found to have Dyslipidemia. Total Cholesterol, TG was found to be significantly higher in test group compared to control.  The mean HDL-cholesterol was found significantly lower in test group compared to control. No significant differences between test and control were observed in VLDL-cholesterol and LDL-cholesterol.CONCLUSIONSSerum lipid profile abnormalities are found high in individuals with depression. Based on the observation of this study, Serum Lipid abnormalities seen in individuals with Depression make them vulnerable to cardiovascular disease.

Relative risk of cardiovascular disease is higher in women with type 2 diabetes, but not in those with prediabetes, as compared with men

2020 ◽  
Author(s):  
Elena Succurro ◽  
Teresa Vanessa Fiorentino ◽  
Sofia Miceli ◽  
Maria Perticone ◽  
Angela Sciacqua ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Cardiovascular Disease ◽  
Longitudinal Study ◽  
Relative Risk ◽  
Hdl Cholesterol ◽  
Cross Sectional Study ◽  
Adverse Outcomes ◽  
Cross Sectional ◽  
Normal Glucose

<b>Objective</b>: Most, but not all studies suggested that women with type 2 diabetes have higher relative risk (RR) for cardiovascular disease (CVD) than men. More uncertainty exists on whether the RR for CVD is higher in prediabetic women compared to men. <p><b>Research Design and Methods</b>: In a cross-sectional study, in 3540 normal glucose tolerant (NGT), prediabetic, and diabetic adults, we compared the RR for prevalent non-fatal CVD between men and women. In a longitudinal study including 1658 NGT, prediabetic, and diabetic adults, we compared the RR for incident major adverse outcomes, including all-cause death, coronary heart disease, and cerebrovascular disease events after 5.6 years follow-up. </p> <p><b>Results:</b> Women with prediabetes and diabetes exhibited greater relative differences in BMI, waist circumference, blood pressure, total, LDL and HDL cholesterol, triglycerides, fasting glucose, hsCRP, and white blood cell count than men with prediabetes and diabetes when compared with their NGT counterparts. We found a higher RR for prevalent CVD in diabetic women (RR 9.29; 95% CI 4.73-18.25; <i>P</i><0.0001) than in men (RR 4.56; 95% CI 3.07-6.77; <i>P</i><0.0001), but no difference in RR for CVD was observed comparing prediabetic women and men. In the longitudinal study, we found that diabetic, but not prediabetic women have higher RR (RR 5.25; 95% CI 3.22-8.56; <i>P</i><0.0001) of incident major adverse outcomes than their male counterparts (RR 2.72; 95% CI 1.81-4.08; <i>P</i><0.0001).</p> <p><b>Conclusions:</b> This study suggests that diabetic, but not prediabetic, women have higher RR for prevalent and incident major adverse outcomes than men. </p>

Correlation of Glycemic Control Parameters in Non-Diabetic Persons with Cardiovascular Risk Scores - Results from a Cross- Sectional Study

2017 ◽  
Vol 68 (1) ◽  
pp. 108-110
Author(s):  
Gina Botnariu ◽  
Norina Forna ◽  
Alina Popa ◽  
Raluca Popescu ◽  
Alina Onofriescu ◽  
...  
Keyword(s):  
Cardiovascular Risk ◽  
Glycemic Control ◽  
Tolerance Test ◽  
Cross Sectional Study ◽  
Risk Scores ◽  
Oral Glucose ◽  
Cross Sectional ◽  
University Of Edinburgh ◽  
Fasting Glycaemia ◽  
The University

To assess the correlation between main parameters of glycemic control and cardiovascular risk scores in non-diabetic persons. Risk scores were calculated by using the University of Edinburgh Risk Calculator. Risk scores are used to estimate the probability of cardiovascular disease in individuals who have not already developed major atherosclerotic disease. We correlated the results of these scores with the parameters that describes the glycaemic profile: preprandial glicaemia, HbA1c and 1 hour and 2 h post-prandial glycaemia, determined during Oral Glucose Tolerance Test (OGTT).Both fasting glycaemia and HbA1c significantly correlated with cardiovascular risk scores calculated for a period of 10 years. The recorded post-prandial glycaemic values at 1h and 2h after glucose loading didn�t significantly correlate with calculated scores, in the study group. The observed correlations underline the importance of glycaemia in the pathogenesis of cardiovascular diseases.

Evaluation of Drug Use Based on WHO Prescribing Indicator in Mizan- Tepi University Teaching Hospital, south Western Ethiopia: A Cross Sectional Study

2020 ◽  
Vol 15 ◽  
Author(s):  
Solomon Hambisa ◽  
Rediet Feleke ◽  
Ameha Zewudie ◽  
Mohammed Yimam
Keyword(s):  
Drug Use ◽  
World Health Organization ◽  
Teaching Hospital ◽  
Cross Sectional Study ◽  
University Teaching ◽  
World Health ◽  
Sectional Study ◽  
Hospital Data ◽  
Cross Sectional ◽  
Health Organization

Background:: Rational drug use comprises aspects of prescribing, dispensing and patient use of medicines for different health problems. This study is aimed to assess drug prescribing practice based on the world health organization prescribing indicators in Mizan-Tepi University teaching hospital. Methods:: An institutional based retrospective cross sectional study was conducted to evaluate prescribing practices in Mizan-Tepi University teaching hospital. Data were collected based on World health organization drug use indicators using prescription papers. 600 prescriptions dispensed through the general outpatient pharmacy of the hospital were collected by systematic random sampling method from prescriptions written for a 1-year time in Mizan-Tepi University teaching hospital. Results:: The present study found that the average number of drugs per prescription was 2.04 ± 0.87 in Mizan-Tepi University teaching hospital with a range between 1 and 5. Prescribing by generic name was 97.6 % and 47.8% of prescriptions contained antibiotics in the hospital. 27.7% of prescriptions contained at least one injectable medication in Mizan-Tepi University teaching hospital. From prescribed drugs, 96.7% of them were prescribed from Ethiopian essential drug list. Conclusion:: Present study indicated that the average number of drugs prescribed per encounter, the percentage of generic prescribing and prescribing from the EDL were close to optimal value. However, the percentage of encounters with antibiotics and injections prescribed were found be very high. Thus, the study highlights some improvements in prescribing habits, particularly by focusing on the inappropriate consumption of antibiotics and injections.

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