Phytochemical analysis, Antioxidant and Antiarthritic activities of different solvent extract of Aegle marmelos L. unripe fruit

2020 ◽  
Vol 13 (6) ◽  
pp. 2759
Author(s):  
G Sivakumar ◽  
K Gopalasatheeskumar ◽  
K Gowtham ◽  
E Sindhu ◽  
K Akash Raj ◽  
...  
Keyword(s):  
Phytochemical Analysis ◽  
Aegle Marmelos ◽  
Unripe Fruit ◽  
Solvent Extract

scholarly journals IN VITRO - ANTIOXIDANT AND PRELIMINARY PHYTOCHEMICAL ANALYSIS OF AEGLE MARMELOS (L.) CORREA. LEAF EXTRACT

2017 ◽  
Vol 10 (6) ◽  
pp. 367
Author(s):  
Samidha M Pawaskar ◽  
Sasangan Kc
Keyword(s):  
Hydroxyl Radical ◽  
Leaf Extract ◽  
Radical Scavenging ◽  
Reducing Power ◽  
Total Phenolic ◽  
Phytochemical Analysis ◽  
Aegle Marmelos ◽  
Leaf Powder ◽  
Phenolic And Flavonoid

Objective: In this study, the leaf powder of Aegle marmelos (L.) Correa. was subjected to preliminary phytochemical and in vitro antioxidant analysis. Methods: The freshly prepared plant leaf extract was subjected to preliminary phytochemical screening, which revealed the presence of alkaloids, tannins, saponins, flavonoids, glycosides, phenolic compounds, terpenoids, and steroids. Reducing power, superoxide (SO) anion radical, nitric oxide (NO) radical, and hydroxyl radical scavenging assays were carried out to evaluate the antioxidant potential of the methanolic leaf extract of this plant. The amounts of total phenolic and flavonoid compounds were also determined. Results: This study has revealed that the A. marmelos (L.) Correa. leaf extract showed considerably high amounts of most of the phytochemicals, total antioxidant capacity, total phenolic, and flavonoid content. The study also indicated that the A. marmelos (L.) Correa. showed comparatively good scavenging activity, i.e., inhibition of hydroxyl radical, NO and SO anion scavenging and reducing power activities when compared with the respective standards. Conclusion: The leaf powder of A. marmelos (L.) Correa. can be used as easily accessible source of natural antioxidant and as a possible food supplement or in pharmaceutical industry.

scholarly journals ANTI BACTERIAL AND BIOFILM INHIBITORY ACTIVITIES OF AEGLE MARMELOS METHANOL LEAF EXTRACT

2021 ◽  
Vol 9 (09) ◽  
pp. 165-173
Author(s):  
Gujjari Sreehitha Pratap ◽  
Keyword(s):  
Antibacterial Activity ◽  
Biologically Active ◽  
Diffusion Method ◽  
Antibiofilm Activity ◽  
Phytochemical Analysis ◽  
Aegle Marmelos ◽  
Leaf Extracts ◽  
Biofilm Inhibition ◽  
Microbial Strains ◽  
Elisa Plate

The Aegle marmelos commonly known as BAEL belongs to family Rutaceae plays a role in traditional culture and medication from ancient periods. This plant lacks sufficient evidences regarding the values and components it has. Therefore, we framed out our studies to evaluate the phytochemical analysis, antibacterial activity, antibiofilm activity. These studies are evaluated using different solvents like methanol, acetone, chloroform, toluene leaf extracts of Aegle marmelos. We evaluated the potency of different solvents leaf extracts using Agar well diffusion method. Antibacterial activity was also evaluated using ELISA plate assay. The potency of different solvents extracts to inhibit biofilm of selected microbial strains. In accordance to results, the leaf extracts revealed the presence of several biologically active phytochemicals with highest quantities of carbohydrates, phenols, alkaloids, flavonoids, tannins, saponins, steroids, aminoacids etc. The antibacterial activity was found significant against microbial strains of both gram positive and gram negative bacteria. These strains showed susceptibility nature towards the different solvents extracts with zone of inhibitions (mm). On the other hand, the inhibition of biofilm was also significant at all tested concentrations. The biofilm inhibition of microbial strains was found significant at 1 XMIC, 2 XMIC, 3 XMIC. Based on our studies here we conclude that the different solvents leaf extracts possessed inhibitory activity against selected human pathogenic organisms.

scholarly journals AEGLE MARMELOS (BAEL PATRA): AN AYURVEDIC PLANT WITH ETHNOMEDICINAL VALUE

2021 ◽  
Vol 12 (3) ◽  
pp. 147-156
Author(s):  
Shailja Choudhary ◽  
Gitika Chaudhary ◽  
Hemlata Kaurav
Keyword(s):  
Skin Diseases ◽  
Review Article ◽  
Pharmacological Properties ◽  
Healing Ulcer ◽  
Aegle Marmelos ◽  
Unripe Fruit ◽  
Plant Parts ◽  
Medicinal Value ◽  
Hindu Temples ◽  
Ethnomedicinal Uses

Aegle marmelos is considered as the most sacred or holy plant which is grown by the sides of Hindu temples. This plant is dedicated to Lord Shiva and is also believed that Lord Shiva resides under the Bael tree. Besides this, the plant is associated with a great medicinal value whose medicinal description is also mentioned in the ancient treatise like Vedas, Puranas, Charaka Samhita and Brihat Samhita and has also been portrayed in the paintings of Ajanta caves. Every part of the Bael plant is used to treat various diseases. In Ayurveda, the plant is used in Panchang form to treat diarrhea, dysentery and ulcer. In folklore, the plant parts are used to treat diabetes, skin diseases and typhoid, wound healing, ulcer, stomachache, jaundice, high BP, malaria, cancer and other diseases. The fruit of the plant is edible and carries great medicinal value because of the presence of vitamins, minerals and various antioxidants. The pulp of the fruit is aromatic, sweet, pale orange and resinous. The unripe fruit pulp of the plant is used to prepare murabba, pudding and juice. The plant is associated with ethnomedicinal uses and possesses various therapeutic and pharmacological properties including antioxidant, anti-diabetic, antihistamine, radio protective, antiulcer, anticancer, cardio-protective, antidiarrheal, antibacterial, antimicrobial, hepatoprotective, anti-inflammatory and antiviral. In this review article, attempts have been made to summarize the phytochemistry, ethnomedicinal, Ayurvedic and pharmacological view of the Bael plant.

scholarly journals Studies on the antidiarrhoeal activity of Aegle marmelos unripe fruit: Validating its traditional usage

2009 ◽  
Vol 9 (1) ◽  
Author(s):  
S Brijesh ◽  
Poonam Daswani ◽  
Pundarikakshudu Tetali ◽  
Noshir Antia ◽  
Tannaz Birdi
Keyword(s):  
Aegle Marmelos ◽  
Unripe Fruit

scholarly journals Effect of aqueous extract of Aegle marmelos unripe fruit on inflammatory bowel disease

2012 ◽  
Vol 44 (5) ◽  
pp. 614 ◽  
Author(s):  
JayantiP Behera ◽  
Bisweswar Mohanty ◽  
YRoja Ramani ◽  
Bandana Rath ◽  
Supriya Pradhan
Keyword(s):  
Inflammatory Bowel Disease ◽  
Aqueous Extract ◽  
Bowel Disease ◽  
Aegle Marmelos ◽  
Unripe Fruit ◽  
Inflammatory Bowel

scholarly journals Anticonvulsant activity of Nigella sativa, Aegle marmelos and Benincasa hispida in Pentylenetetrazole induced seizure in Swiss albino mice

2016 ◽  
Vol 7 (3) ◽  
pp. 97-102
Author(s):  
Rejeesh Edavan Puthallath ◽  
Lovelyn Joseph ◽  
Kumaraswamy Kademane ◽  
Sudarshanram Narayan Rao
Keyword(s):  
Nigella Sativa ◽  
Ethanolic Extract ◽  
Water Bath ◽  
Control Group ◽  
Absence Seizure ◽  
Phytochemical Analysis ◽  
Aegle Marmelos ◽  
Swiss Albino Mice ◽  
Benincasa Hispida ◽  
Albino Mice

Aims and Objectives: To test anticonvulsant properties of three medicinal plants with pentylenetetrazole induced seizure test in Swiss albino mice.Materials and Methods: Herbs selected for the work (leaves of Aegle marmelos, seed of Nigella sativa, and fruit of Benincasa hispida) were collected locally from Mangalore, India and were authenticated by a Taxonomist. Aqueous extract of Aegle marmelos leaves (AmAE) and  Ethanolic extract of Nigella sativa seeds (NsEE) were prepared by Soxhlet extraction and separated from solvent using a water bath. Benincasa hispidafruit juice (BhE) was filtered and dried on a water bath. Qualitative phytochemical analysis of the test extracts were done with Preliminary chemical reaction tests, and Liquid chromatography–mass spectrometry (LC/MS). Male Swiss albino mice, 3-4 months of age, weighing 25-30g were used in the study. Extracts and vehicle were administered orally 1 hour prior to inducing convulsions. Test employed for screening anticonvulsant properties was Pentylenetetrazole (PTZ) induced seizure test [60mg/kg/i.p]. Animals were treated with extracts at a dose of 900mg/kg orally. The results were compared with control group and test for analysis of variance and significance were done (ANOVA, Dunnett’s test).Results: Aqueousextract of Aeglemarmelos leaves and Ethanolic extract of Nigella sativa seeds possess anticonvulsant property in Pentylenetetrazole (PTZ) induced seizure model, Crude extract of Benincasahispida fruits did not show statistically signifi cant anticonvulsant property.Conclusions: Aeglemarmelos leaf and Nigella sativa seed possess anticonvulsant propertiesin pentylenetetrazole induced seizures, this is in accordance with many other publishedreports on the same herbs with different animal models and indicates effectiveness inhuman absence seizure patients.Asian Journal of Medical Sciences Vol. 7(3) 2016 97-102

scholarly journals Phytochemical Analysis of Selected Medicinal plants of India

2019 ◽  
Vol 2 (1) ◽  
pp. 19-23
Author(s):  
Narendra Anant Kulkarni ◽  
Jayashree Mane
Keyword(s):  
Cardiac Glycosides ◽  
Chemical Constituents ◽  
Antioxidant Properties ◽  
Phytochemical Analysis ◽  
Tribulus Terrestris ◽  
Mimosa Pudica ◽  
Aegle Marmelos ◽  
Calotropis Gigantea ◽  
Achyranthes Aspera ◽  
Cissus Quadrangularis

The present study has revealed the presence of phytochemicals considered as active medicinal chemical constituents. Important medicinal phytochemicals such as terpenoids, flavonoids, phenols, tannins, steroids, glycosides were studied in the collected samples. Plant Aegle marmelos Corr. having all these phytochemicals. Saponin was found only in two plants out of nine plants i.e. Achyranthes aspera Linn. and Semecarpus anacardium Linn. Terpenoids were found in Aegle marmelos Corr., Calotropis gigantea Linn.R.Br., Mimosa pudica Linn. Terpenoids are reported to have anti-inflammatory, antiviral, antimalarial, inhibition of cholesterol synthesis and antibacterial. Cardiac glycosides content was found in Achyranthes aspera Linn., Aegle marmelos Corr., Mimosa pudica Linn., Tribulus terrestris Linn., Calotropis gigantea Linn.R.Br., Ricinus communis Linn.. Cardiac glycosides have been used for over two centuries as a stimulant in case of cardiac failure. The flavonoids were found in Achyranthes aspera Linn., Aegle marmelos Corr., Calotropis gigantea Linn., Mimosa pudica Linn., Cissus quadrangularis Linn. Mart., Tribulus terrestris Linn. The biological functions of flavonoids apart from its antioxidant properties include protection against allergies, inflammation, free radicals, platelet aggregation, microbes, ulcers, hepotoxins, viruses and tumors.

Reliable analysis of volatile compounds from small samples of Eucalyptus magnificata (Myrtaceae)

2018 ◽  
Vol 31 (3) ◽  
pp. 232 ◽  
Author(s):  
Timothy L. Collins ◽  
Rose L. Andrew ◽  
Ben W. Greatrex ◽  
Jeremy J. Bruhl
Keyword(s):  
Solvent Extraction ◽  
Small Samples ◽  
Gas Chromatography Mass Spectrometry ◽  
Phytochemical Analysis ◽  
Herbarium Specimens ◽  
Plant Systematics ◽  
Leaf Sample ◽  
Solvent Extract ◽  
Significant Difference ◽  
Number Of Leaves

Phytochemistry is a source of data for plant systematics. This tool has much more value if herbarium specimens can be used without major damage and if results are comparable with fresh samples. A modified method for the solvent extraction of eucalypt leaf oils for phytochemical analysis and chemotaxonomy studies, including historical herbarium samples by gas chromatography–mass spectrometry (GC-MS), has been statistically assessed using Eucalyptus magnificata L.A.S.Johnson & K.D.Hill leaves. Leaf sample size was reduced by a factor of 250 to minimise damage to herbarium specimens, reduce solvent volume and simplify preparation of solvent extract before analysis. Leaf sampling treatments assessed the effects of the number of leaves and post-harvest air-drying on variation in components in the solvent extract. The results showed no statistically significant effect of leaf mass or the number of leaves used in GC-MS analyses on the precision of the measurements, but a significant difference among treatments for some oil constituents, particularly 1,8-cineole. Most differences in terpenoid concentration were due to variation among plants rather than extraction treatments. Extracts from air-dried herbarium leaves up to 44 years old were directly comparable with those from fresh leaves. Solvent extraction in 2 mL GC-MS vials of ~0.5 cm2 (16 mg) of leaf material, using fragments of fresh or air-dried leaves, drastically reduced sample and solvent volumes and showed that sampling from E. magnificata herbarium specimens for chemotaxonomy and chemotyping is a valid method, enabling broader sampling with much lower costs than for traditional fieldwork collections.

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