proportion and risk factors of fatal outcomes among severely and critically ill COVID-19 patients: A hospital experience, Baghdad, Iraq 2021

Background: Severe forms of Coronavirus disease 2019 (COVID‐19) were found among 6 - 10% of all COVID-19 patients. Acute respiratory distress syndrome ARDS is non-cardiogenic pulmonary edema manifested by the rapid development of shortness of breath, tachypnea, and hypoxemia. Patients’ outcomes after critical care for COVID-19 have not been adequately documented in this low-resource environment, despite advocacy for prevention and response measures in low- and middle-income countries. Objectives: To highlight the rate of severe illness among COVID-19 patients and its associated factors in Al-Imam Ali Hospital, Baghdad-Iraq 2021. Patients and Methods: A descriptive cross-sectional study on cases with severe and critical COVID-19 illness (with ARDS) admitted to the isolation ward in Al-Imam Ali Hospital from 23 March to 23 May, 2021. All COVID-19 patients admitted in a severe or critical state were included. A data collection form was filled by the researcher. The P value of < 0.05 was used to determine statistical significance. Ethical Approval was obtained. Results: A total of 504 severely ill COVID-19 patients were included in this study. There were 71 (14.1%) patients below 45 years of age. Males formed 40.9% of patients while that of females was 59.1%. Fever was the presenting symptom in 381 (75.6%) patients, 197 (39.1%) patients had anosmia, and 192 (38.1%) had ageusia. There were 358 (71.0%) survivors while 146 (29.0%) died. Patients aged 65 years or more had more possible risk for death than those below 65 years (OR=1.14, 95% CI =0.6-2.2). Female gender appeared to be protective compared to male gender (OR=0.52, 95% CI =0.35-0.77). Ex-smokers had a higher risk than non-smoker and current smokers (OR for ex-smoker=4.38, 95% CI 2.6-7.5), and (OR for current smoker=1.7, 95% CI 0.98-3). Renal disease was found to be a risk factor leading to death (OR=2.9; 95% CI=1.73-5.1). Diabetes Mellitus, respiratory diseases, and solid cancer showed a high risk for death, [OR=2.3, 95% CI=1.4-4; OR=1.7; 95% CI=1.1-2.9, OR=8, 95% CI=3.3-19 respectively]. Patients with three comorbidities had a higher mortality risk, OR=1.6, 95% CI=1.3-2. Conclusion: This study concluded that mortality of severely and critically ill COVID-19 patients was 29%, and males and older patients were risk factors for death. In addition to; ex-smoker, alcoholic, and patients with baseline comorbidities appeared to be risk factors for mortality. Finally; laboratory tests and Pao2/Fio2 ratio can be used to predict the outcome.

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Seroprevalence of human Brucellosis and associated risk factors among high-risk occupations in Mbeya Region of Tanzania

Journal of Epidemiological Research ◽

10.5430/jer.v6n1p1 ◽

2020 ◽

Vol 6 (1) ◽

pp. 1 ◽

Cited By ~ 1

Author(s):

Frederick D. Sagamiko ◽

Ruth L. Mfune ◽

Bernard M. Hang’ombe ◽

Esron D. Karimuribo ◽

Alfred M. Mwanza ◽

...

Keyword(s):

Public Health ◽

Risk Factors ◽

Statistical Significance ◽

Raw Milk ◽

Enzyme Linked Immunosorbent Assay ◽

Human Brucellosis ◽

P Value ◽

Cross Sectional ◽

Occupationally Exposed ◽

Associated Risk Factors

Background: Brucellosis is a bacterial zoonotic disease of public health and economic importance. A cross-sectional study was conducted in Mbeya region between November 2015 and January 2016 to investigate the seroprevalence of human brucellosis and identify associated risk factors among individuals in risky occupations. Methods: A total of 425 humans from six occupational categories were serially tested for Brucella antibodies using the Rose Bengal Plate Test (RBPT) and competitive Enzyme Linked Immunosorbent Assay (c-ELISA), for screening and confirmation, respectively. A questionnaire survey was also administered to participants to collect epidemiological data. Results: The overall seroprevalence among the occupationally exposed individuals was 1.41% (95% CI: 00.64-3.12). Seroprevalence was higher among butcher men 5.6% (95% CI: 1.68-5.26), herds men 1.35% (95% CI: 0.18-9.02); and abattoir workers 1.1% (95% CI: 0.26-4.22) although there was no statistical significance. (P value = .18). Seroprevalence was also higher among men (1.8%) compared to females (0%) (P value = .19). and also, among those aged < 11 years (2.5%). Individuals who consumed raw milk had a higher seroprevalence (1.56%) compared to those who drunk boiled milk while seropositivity was 0.88% among those who assisted animals during parturition (P value = .49). Butcher men were at higher risk of exposure compared to other occupational categories. Our findings show the presence of brucellosis in occupationally exposed individuals in Mbeya region.Conclusion: There is need to sensitize the concerned professions in order to reduce the risk of acquiring Brucella infections from animals and animal products This also calls for public health awareness about the disease, and implementation of measures to prevent further spread of brucellosis within and outside the study area.

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A study of the risk factors of various arrhythmias in patients with coronary heart disease

International Journal of Advances in Medicine ◽

10.18203/2349-3933.ijam20174285 ◽

2017 ◽

Vol 4 (5) ◽

pp. 1369

Author(s):

Puneet Patil ◽

Aamera Sait ◽

Dilip Ratan Patil

Keyword(s):

Diabetes Mellitus ◽

Risk Factors ◽

Statistical Significance ◽

Tertiary Care ◽

P Value ◽

Care Hospital ◽

Av Block ◽

Cross Sectional ◽

Multiple Risk Factors ◽

Multiple Risk

Background: Complications like arrhythmias, cardiac failure, cerebrovascular and mechanical complications. Among these complications, arrhythmias are the most common complication of acute myocardial infarction. The objective of this study was to study the risk factors of various arrhythmias in patients with coronary heart disease.Methods: Present study was a hospital based cross sectional study conducted at department of General Medicine of a tertiary care hospital for a period of two years among 102 patients. Detailed history, clinical examination, investigation was done. All patients were followed for one year to assess the outcome among them. All data was entered in the Microsoft Excel worksheet and analyzed using proportions.Results: Arrhythmias were more common with low ejection fraction (72.73%). The overall mortality was 7.84%. Ventricular fibrillation was seen in 50% of the patients who did not receive thrombolytic therapy. First-degree AV block and second-degree AV block were present in 6.25% and 7.50% respectively and did not affect the mortality while complete heart block was present in 8.75% and mortality rate of 28.57% with right ventricular involvement. Risk factors like smoking, alcohol, hypertension, diabetes mellitus and obesity had higher incidence of arrhythmias but was not found to have any statistical significance (p >0.05). However, patients having multiple risk factors strongly associated with the high mortality in statistically significant manner (p value 0.0006).Conclusions: Patients with risk factors like smoking, alcohol, hypertension, diabetes mellitus and obesity had higher incidence of arrhythmias. Multiple risk factors increase the incidence of both arrhythmias and mortality (67% mortality with 4 risk factors and 75% mortality with 5 risk factors).

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Prevalence of overweight and its associated risk factors among adolescents: A cross-sectional study in peri-urban area of Nepal

10.21203/rs.3.rs-919325/v1 ◽

2021 ◽

Author(s):

Elina Khatri ◽

Rajesh Kumar Yadav ◽

Sushila Baral ◽

Sudha Poudel ◽

Kedar Prasad Baral

Keyword(s):

Risk Factors ◽

Nutritional Status ◽

Urban Areas ◽

Weight Status ◽

Statistical Significance ◽

Anthropometric Measurement ◽

P Value ◽

Healthy Weight ◽

Cross Sectional ◽

Rapid Urbanization

Abstract Background Adolescence, being a crucial stage for experimentation and acceptance of new behavioral and lifestyle choices, is detrimental to their nutritional status. The nutritional status of adolescents being shaped by socio-cultural, environmental, and economic factors has also been impacted by their food habits and level of physical activity. The current nutritional shift and rapid urbanization had emerged overweight as an additional burden for consistently prevalent undernutrition issues. So, the study aimed to identify the prevalence of and risk factors for overweight among school adolescents. Methods A school-based cross-sectional analytical study was carried out among school adolescents in a Sub-metropolitan city of Nepal. A random sample of 279 adolescents from nine schools was included in the study. The anthropometric measurement of the height and the weight were measured as per the standard. The odds ratio with a 95% CI was calculated and a p-value of ≤ 0.05 was considered as cut off for statistical significance by fitting into the final multivariable logistic regression. Results The overall prevalence of overweight was obtained as 9.31% (95% CI: 6.40 − 13.3). The mean age of respondents was 15.5 years. The early aged adolescents were more overweight than compared to middle-aged adolescents (AOR: 0.27, CI: 0.028–2.67) and late adolescents (AOR: 0.66, CI: 0.068–6.44) respectively. Similarly, adolescents residing in rural areas had 0.35 (AOR = 0.33, CI: 0.030–3.71) odds of being overweight compared to their counterparts. Adolescents with sedentary behavior were 4 times (AOR = 3.51, CI: 0.79–15.54) more likely of being overweight than their counterparts. Conclusions Overweight among adolescents in urban areas has emerged as an alarming issue with the increasing burden. It is therefore pertinent to emphasize adolescents to improve healthy weight status.

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Knowledge about stroke among adults in Sharjah, United Arab Emirates

International Journal of Research in Medical Sciences ◽

10.18203/2320-6012.ijrms20194194 ◽

2019 ◽

Vol 7 (10) ◽

pp. 3632

Author(s):

Rami A. Karkout ◽

Omar Shamaa ◽

Sara T. Al Ammour ◽

Rana S. Abd Elmaged ◽

Lujain A. Al Kassar ◽

...

Keyword(s):

Risk Factors ◽

United Arab Emirates ◽

Age Groups ◽

Signs And Symptoms ◽

Female Gender ◽

Visual Disturbance ◽

P Value ◽

Cross Sectional ◽

Awareness Programs ◽

Cross Sectional Design

Background: In UAE, stroke is the second leading cause of disability after RTA, where annually 8,000 to 10,000 patients get a stroke. Our aim is to identify the knowledge levels of stroke among Sharjah’s adult citizens.Methods: Using self-administered questionnaires, in a cross-sectional design, a non-probability convenience sampling method was used to enrol subjects. Eligible subjects were above 18 years of age, comprehended Arabic or English, and are currently residing in Sharjah. The questionnaire was 17 questions structured in 5 sections which included: demographics, general knowledge, knowledge of signs and symptoms, risk factors, and appropriate response towards stroke. SPSS V.22 was used to analyse the data. Percentages, means, and ANOVA were used. A P-value less than 0.05 was considered to be statistically significant.Results: The study included 426 subjects, mean age was 35.1 years, 65.2% were females. 51.8% of the subjects claimed they know what stroke is, out of whom 24.3% provided incorrect descriptions. The mean knowledge level of signs and symptoms was 55.4%, and of risk factors was 40.6%. Visual disturbance was the least identified of the five signs and symptoms (38.0%). Female gender, African American race, and age above 60, were the least identified of the 8 risk factors (4.7%, 3.5%, 19.8% respectively). Better knowledge was associated with increased age and higher education. Conclusion: The majority of the sample showed an average to low level of knowledge. Such results indicate the importance of implementing more awareness programs that target younger age groups in the community.

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Atorvastatin-Induced Myalgia in Iranian Patients: A Hospital-Based Study to Determine the Prevalence and Associated Risk Factors

Journal of Pharmaceutical Care ◽

10.18502/jpc.v8i4.5239 ◽

2021 ◽

Author(s):

Farzaneh Dastan ◽

Jamshid Salamzadeh ◽

Ali Saffaei ◽

Yasaman Nabavi ◽

Mohammad Abbasinazari

Keyword(s):

Risk Factors ◽

Demographic Data ◽

Female Gender ◽

Cross Sectional Study ◽

Iranian Population ◽

P Value ◽

Cross Sectional ◽

Multivariate Logistic Model ◽

Incidence Risk ◽

Associated Risk Factors

Background: Statins are associated with several muscle complaints, such as: myositis, myalgia, muscle weakness, muscle spasms and rhabdomyolysis. Age, race, gender, dose of statin, concomitant medications, concomitant disorders and genetics have been reported as the most important risk factor for statin-induced myalgia. The aim of this study was to determine the prevalence and associated risk factors of atorvastatin-induced myalgia in hospitalized patients in Tehran, Iran. Methods: In this cross sectional study, a questionnaire was developed by expert panel opinions. The questionnaire was included various items regarding demographic data and myalgia evaluation factors. Seven hundred patients were included in the study and necessary data were gathered. Finally, the data were analyzed and a statistical model was designed to predict the myalgia risk factors. Results: The rate of myalgia was 44.3% among studied patients. By developing a multivariate logistic model, female gender (OR= 0.47, P-value<0.001) was one of the most important factors in myalgia occurrence. Conclusion: The results of this study suggest that gender, age, atorvastatin dose, duration of atorvastatin usage and presence of myotoxic disease are the main predictors of myalgia in Iranian population. Hence, the findings of this study can be considered to predict the myalgia incidence risk in Iranian population.

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Prevalence of Tungiasis and its risk factors of among children of Mettu woreda, southwest Ethiopia, 2020

PLoS ONE ◽

10.1371/journal.pone.0262168 ◽

2022 ◽

Vol 17 (1) ◽

pp. e0262168

Author(s):

Sime Daba Jorga ◽

Yohannes Lulu Dessie ◽

Mohammed Reshad Kedir ◽

Dereje Oljira Donacho

Keyword(s):

Risk Factors ◽

Risk Factor ◽

School Attendance ◽

Statistical Significance ◽

Skin Lesions ◽

P Value ◽

Limited Information ◽

Cross Sectional ◽

Permanent Disability ◽

Southwest Ethiopia

Tungiasis is caused by the flea tunga penetrans and results in painful skin lesions, skin infections, and permanent disability. However, limited information is available that shows the magnitude of the problem and its risk factors that help for intervention in Ethiopia. The goal of this study was to determine the prevalence and risk factors of tungiasis in children aged 5 to 14 in Mettu woreda in 2020. A community based cross sectional study was conducted among randomly selected kebeles of Mettu woreda, in Southwest Ethiopia. To select study participants, multistage sampling was used. The data were collected through physical examination of the children, interview of parents/guardians of the children, and observation of the home environment using checklists and questionnaires. The descriptive analysis was done for socio-demographic characteristics, prevalence of tungiasis, and housing conditions. A logistic regression analysis was performed, and variables in multivariable regression reported odds ratios and their 95% confidence intervals once the variables were identified using a p-value of 0.05 as a risk factor of statistical significance. The prevalence of tungiasis among children 5–14 years of age in Mettu rural woreda was 52 percent (n = 821). As a risk factor, large family size (AOR: 2.9, 95% CI: 2.13, 4.40); school attendance (AOR: 1.5, 95% CI: 1.02, 2.18), floor inside the house (AOR: 3.8, 95% CI: 1.76, 8.43); having sleeping bed (AOR: 0.16, 95% CI: 0.03, 0.82); access to protected water sources (AOR: 0.24, 95% CI: 0.15, 0.39); access to improved toilet facilities(AOR: 0.63: 95% CI: 0.44, 0.89); access to electric services (AOR: 0.30, 95% CI: 0.15, 0.62); and lack of own farmland (AOR: 0.36, 95% CI: 0.26, 0.50) were found. Therefore, planning and implementation of interventions focus on those risk factors that are particularly important. Water, sanitation and hygiene interventions, and livelihood improvement interventions are required to solve the problem in the setting.

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Prevalence of Coronary Artery Ectasia and Associated Risk Factors

Shiraz E-Medical Journal ◽

10.5812/semj.104038 ◽

2020 ◽

Vol In Press (In Press) ◽

Author(s):

Seyyed Ali Moezi Bady ◽

Elham Rezvanian ◽

Nahid Azdaki ◽

Saeede Khosravi Bizhaem ◽

Toba Kazemi

Keyword(s):

Diabetes Mellitus ◽

Risk Factors ◽

Coronary Artery ◽

Statistical Significance ◽

Demographic Data ◽

Normal Coronary Artery ◽

P Value ◽

Coronary Artery Ectasia ◽

Cross Sectional ◽

Low Hdl

Objectives: This study aimed to evaluate the incidence of coronary artery ectasia (CAE) and its associated factors in the East of Iran. Methods: A cross-sectional study was conducted on 2,795 patients undergoing coronary angiography between 2011 and 2017. Patients were categorized into three groups: Coronary artery ectasia, normal coronary artery, and coronary artery stenosis. Patients' demographic data, cardiac risk factors, and angiographic results were extracted from medical records. Then, information on CAE patients was evaluated. Data were analyzed by the independent t-test, Mann-Whitney test, and chi-square test. Statistical significance was defined by a P-value ≤ 0.05. Results: The prevalence of CAE was 3.04%. The mean age of CAE patients was significantly higher than that of normal coronary artery patients (53.98 ± 9.97). The proportion of men was significantly lower in the CAE group (48.2%) than in the CAS group (62.1%) but higher than in the normal group (32.3). Body mass index (BMI) and low HDL (high-density lipoprotein) were higher in the CAE group, but diabetes mellitus was lower than in the CAS group. Conclusions: The prevalence of CAE was low in our study. Old age, male sex, obesity, and low HDL were CAE risk factors, but diabetes mellitus was a preventing factor in our study.

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Peptic ulcer disease: a cross-sectional study of symptoms and risk factors among students at Jimma University, Ethiopia

Gastrointestinal Nursing ◽

10.12968/gasn.2021.19.2.36 ◽

2021 ◽

Vol 19 (2) ◽

pp. 36-40

Author(s):

Melkamu Gelan ◽

Abdisa Eba ◽

Desalegn Nigatu ◽

Bonsa Amsalu

Keyword(s):

Risk Factors ◽

Peptic Ulcer ◽

Peptic Ulcer Disease ◽

Statistical Significance ◽

Cross Sectional Study ◽

P Value ◽

Sectional Study ◽

Cross Sectional ◽

Ulcer Disease ◽

Jimma University

Background: Peptic ulcer disease (PUD), which includes gastric and duodenal ulcers, is a common condition with symptoms including epigastric or abdominal pain. It is multifactorial, with physiological, demographic and environmental risk factors, some of which make it more prevalent in developing countries. Aims: This study aims to assess the symptoms of and risk factors for PUD among students at Jimma University, Jimma, Ethiopia. Methods: This institutional based cross-sectional study design used a self-administered questionnaire to collect data for analysis. This included logistic regression analysis, in which a p-value of <0.05 at 95% CI indicated statistical significance. Findings: Of the 240 respondents, 41.3% had symptoms indicative of PUD. Most students developed symptoms after enrolling at university and primarily managed them with medication. PUD-like symptoms were found to be associated with year of study, frequent Non-steroidal anti-inflammatory drugs(NSAIDs use, smoking, prolonged fasting and anxiety. Conclusions: PUD is highly prevalent in this setting. Therefore, the university may wish to raise awareness of PUD and aim to reduce anxiety among students.

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Awareness of radiation doses and risks among radiology residents, fellows, specialists, consultants and technologists in Jeddah, Saudi Arabia: Cross-Sectional Study. (Preprint)

10.2196/preprints.14460 ◽

2019 ◽

Author(s):

Bashayer Hassan Shuaib ◽

Rahaf Hisham Niazi ◽

Ahmed Haitham Abduljabbar ◽

Mohammed Abdulraheem Wazzan

Keyword(s):

Interventional Radiology ◽

Ionizing Radiation ◽

Statistical Significance ◽

Knowledge Score ◽

P Value ◽

Radiation Doses ◽

Cross Sectional ◽

The Right ◽

Interventional Radiology Procedures ◽

Radiology Staff

BACKGROUND Radiology now plays a major role to diagnose, monitoring, and management of several diseases; numerous diagnostic and interventional radiology procedures involve exposure to ionizing radiation. Radiology now plays a major role to diagnose, monitoring, and management of several diseases; numerous diagnostic and interventional radiology procedures involve exposure to ionizing radiation. OBJECTIVE This study aimed to discover and compare the awareness level of radiation doses, protection issues, and risks among radiology staff in Jeddah hospitals. METHODS A cross-sectional survey containing 25 questions on personal information and various aspects of radiation exposure doses and risks was designed using an online survey tool and the link was emailed to all radiology staff in eight tertiary hospitals in Jeddah. The authors were excluded from the study. A P-value of < .05 was used to identify statistical significance. All analyses were performed using SPSS, version 21. RESULTS Out of 156 participants the majority 151 (96.8%) had poor knowledge score, where the mean scores were 2.4±1.3 for doses knowledge, 2.1±1.1for cancer risks knowledge, 2.3±0.6 for general information, and 6.7±1.9 for the total score. Only 34.6% of the participants were aware of the dosage of a single-view chest x-ray, and 9.0% chose the right answer for the approximate effective dose received by a patient in a two-view. 42.9% were able to know the correct dose of CT abdomen single phase. There is a significant underestimation of cancer risk of CT studies especially for CT abdomen where only 23.7% knew the right risk. A p-value of <0.05 was used to identify statistical significance. No significant difference of knowledge score was detected regarding gender (P =.2) or work position (P=.66). CONCLUSIONS Our survey results show considerable inadequate knowledge in all groups without exception. We recommended a conscientious effort to deliver more solid education and obtain more knowledge in these matters and providing periodic training courses to teach how to minimize the dose of radiation and to avoid risk related. CLINICALTRIAL not applicable

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A risk index for COVID-19 severity is associated with COVID-19 mortality in New York City

BMC Public Health ◽

10.1186/s12889-021-11498-x ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Wil Lieberman-Cribbin ◽

Naomi Alpert ◽

Raja Flores ◽

Emanuela Taioli

Keyword(s):

Risk Factors ◽

New York ◽

New York City ◽

York City ◽

Underserved Populations ◽

Risk Index ◽

Data Repository ◽

Severe Illness ◽

Mortality Data ◽

Cross Sectional

Abstract Background New York City (NYC) was the epicenter of the COVID-19 pandemic, and is home to underserved populations with higher prevalence of chronic conditions that put them in danger of more serious infection. Little is known about how the presence of chronic risk factors correlates with mortality at the population level. Here we determine the relationship between these factors and COVD-19 mortality in NYC. Methods A cross-sectional study of mortality data obtained from the NYC Coronavirus data repository (03/02/2020–07/06/2020) and the prevalence of neighborhood-level risk factors for COVID-19 severity was performed. A risk index was created based on the CDC criteria for risk of severe illness and complications from COVID-19, and stepwise linear regression was implemented to predict the COVID-19 mortality rate across NYC zip code tabulation areas (ZCTAs) utilizing the risk index, median age, socioeconomic status index, and the racial and Hispanic composition at the ZCTA-level as predictors. Results The COVID-19 death rate per 100,000 persons significantly decreased with the increasing proportion of white residents (βadj = − 0.91, SE = 0.31, p = 0.0037), while the increasing proportion of Hispanic residents (βadj = 0.90, SE = 0.38, p = 0.0200), median age (βadj = 3.45, SE = 1.74, p = 0.0489), and COVID-19 severity risk index (βadj = 5.84, SE = 0.82, p < 0.001) were statistically significantly positively associated with death rates. Conclusions Disparities in COVID-19 mortality exist across NYC and these vulnerable areas require increased attention, including repeated and widespread testing, to minimize the threat of serious illness and mortality.

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