scholarly journals Cholinesterase Level in Erythrocyte or Serum: Which is More Predictive of the Clinical Outcome in Patients with Acute Organophosphate Poisoning?

2018 ◽  
Vol 12 (5) ◽  
pp. 23-26
Author(s):  
Mohammad Majidi ◽  
◽  
Mohammad Delirrad ◽  
Ali Banagozar Mohammadi ◽  
Mona Najaf Najafi ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Clinical Outcome ◽  
Demographic Data ◽  
Cross Sectional Study ◽  
Activity Level ◽  
Serum Cholinesterase ◽  
Organophosphate Poisoning ◽  
Intratracheal Intubation ◽  
Laboratory Findings ◽  
Cross Sectional

Background: Acute organophosphate poisoning (AOPP) is related to several clinical complications that may be fatal. The aim of this study was to evaluate the effects of demographic, clinical and laboratory findings on AOPP outcome. Methods: In this retrospective cross-sectional study, medical records of all patients with AOPP admitted to Imam Reza Hospital, Mashhad, Iran, were reviewed from January 2016 to December 2017. Demographic data, clinical presentations, erythrocyte cholinesterase (RBC-ChE) and serum cholinesterase (S-ChE) activities were studied and evaluated in relation to clinical outcome of the patients. Results: A total of 64 patients (37 male, 27 female) were evaluated from whom 6 patients (9.4%) died. Statistically significant relationships were found between the outcome of the patients and RBC-ChE activity (p =0.008), intratracheal intubation (p=0.003), and abnormal blood pressure (p =0.009). Despite the lower mean S-ChE levels in the deceased patients and loss of consciousness in 42.2% (n=27) of patients, there was no statistically significant correlations between these factors and patients’ outcome (p =0.147, p =0.075, respectively). Conclusion: RBC-ChE activity, need for intratracheal intubation, and abnormal blood pressure on admission were important predictive factors in the clinical outcome of AOPP. Although S-ChE activity, level of consciousness, white blood cell count and blood glucose level on admission provide useful information, these data had no prognostic value in patients with AOPP.

scholarly journals Comparison of Urinary Adiponectin in the Presence of Metabolic Syndrome in Peri- and Postmenopausal Women

2021 ◽  
Author(s):  
Patsama Vichinsartvichai ◽  
Rattana Teeramara ◽  
Titima Jirasawas ◽  
Prirayapak Sakoonwatanyoo
Keyword(s):  
Blood Pressure ◽  
Metabolic Syndrome ◽  
Postmenopausal Women ◽  
Demographic Data ◽  
Diagnostic Value ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Screening And Diagnosis ◽  
Baseline Demographic

Abstract Objectives To find the association between urinary adiponectin and metabolic syndrome (MetS) in peri- and postmenopausal women and its potential application as a noninvasive screening for MetS. Methods A cross-sectional study was conducted in healthy peri- and postmenopausal women (defined by STRAW+10 staging) age at least 40 years who attended annual checkup or menopause clinic were recruited. Baseline demographic data, MENQOL, anthropometric measurements, blood pressure, laboratory (FBS, total cholesterol, HDL-C, LDL-C, TG) and urinary adiponectin were collected. The MetS was diagnosed according to JIS 2009. Results 290 peri- and postmenopausal women had participated. The prevalence of Mets among our participants was 18%. Urinary adiponectin levels were similar in peri- and postmenopausal women with and without MetS (2.6±2.2 vs 2.3±1.9 ng/mL, respectively, P = 0.55). Urinary adiponectin provides no diagnostic value for MetS (AUC = 0.516). Conclusions Urinary adiponectin has no role in screening and diagnosis of MetS in peri- and postmenopausal women. The quest toward noninvasive screening for MetS is still going on.

scholarly journals Identification of Novel Classes for Patients With Lupus Nephritis Using Two-step Cluster Model

2021 ◽  
Author(s):  
Ting Huang ◽  
Shasha Xie ◽  
Liqing Ding ◽  
Hui Luo
Keyword(s):  
Cluster Analysis ◽  
Evaluation System ◽  
Demographic Data ◽  
White Blood Cells ◽  
Damage Index ◽  
Cross Sectional Study ◽  
Laboratory Findings ◽  
Cross Sectional ◽  
Mild Disease ◽  
Cluster 2

Abstract Objectives: To identify and reclassify the patients in the LN cohort, and to further analyze the prominent clinical features and clinical significance of each cluster of patients.Methods: This is a cross-sectional study of a cohort of 635 LN patients from the Rheumatology Department of Xiangya Hospital of Central South University. Demographic data, laboratory findings and clinical evaluation system include physician’s global assessment and the SLICC/ACR Damage Index were collected. Using two-step cluster analysis, patients with similar clinical property were identified and compared.Results: Among the 635 LN patients, 599 patients (94.3%) were female. The mean age of the patients were 33.8 ± 10.4 years. Three subgroups were identified by two-step cluster analysis. Cluster 1 included 130 (20.5%) patients, Cluster 2 included 132(20.8%) patients and Cluster 3 included 373 (58.7%) patients. Cluster 3 was the largest group of mild disease activity, patients in this cluster had lower white blood cells, neutrophils, lymphocytes and mean SDI scores compared to those in the other two clusters. Cluster 1 was the smallest group of severe damage, patients in this cluster had multiple positive auto-antibodies, higher SDI scores and lower complement level. Patients of cluster 2 had the highest levels of granulocytes, but the results of other laboratory tests were roughly between the cluster 1 and cluster 3.Conclusions: This study reclassified three groups of LN patients in a large cohort. Our research shows that the multiple positive ANA antibody may be related to the high SDI score of LN patients. Clinicians can identify patients at different stages through cluster analysis to better implement prognosis.

Relative and Cumulative Effects of Hypertension Self-Care Behaviors on Blood Pressure

2019 ◽  
Vol 42 (3) ◽  
pp. 157-164
Author(s):  
Jan Warren-Findlow ◽  
Lisa M. Krinner ◽  
Erin Vinoski Thomas ◽  
Maren J. Coffman ◽  
Benjamin Gordon ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Assessment Tool ◽  
Self Care ◽  
Cross Sectional Study ◽  
Activity Level ◽  
Cumulative Effects ◽  
Cross Sectional ◽  
Partial Correlations ◽  
Valid Assessment ◽  
Individual Self

New recommendations for hypertension (HTN) diagnosis and treatment highlight the role of self-care activities in managing blood pressure (BP). This cross-sectional study investigated the predictive validity of the Hypertension Self-Care Activity Level Effects (H-SCALE) measure and examined the relative and cumulative effects of HTN self-care adherence on BP. We pooled baseline data from three studies ( N = 79), resulting in a gender and racially balanced sample. Partial correlations determined the relative effects of individual self-care behaviors on BP. We modeled the relationship between adherence to self-care behaviors and BP control using logistic regression. Physical activity had the greatest correlation with systolic BP. Adherence to each additional self-care behavior increased the odds of systolic BP control by 88% (95% confidence interval (CI) = [1.20, 2.96]) and diastolic BP control by 74% (95% CI = [1.10, 2.75]). Results provide further evidence that the H-SCALE is a valid assessment tool and should be adopted by clinicians to aid in improving BP management.

scholarly journals Does the type of sedentary behaviors influence blood pressurein adolescents boys and girls? A cross-sectional study

2018 ◽  
Vol 23 (8) ◽  
pp. 2575-2585 ◽  
Author(s):  
Luciano Machado Ferreira Tenório de Oliveira ◽  
Raphael Mendes Ritti-Dias ◽  
Breno Quintella Farah ◽  
Diego Giulliano Destro Christofaro ◽  
Mauro Virgílio Gomes de Barros ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Video Games ◽  
High Blood Pressure ◽  
Television Viewing ◽  
Cross Sectional Study ◽  
Activity Level ◽  
Viewing Time ◽  
Sedentary Behaviors ◽  
Sectional Study ◽  
Cross Sectional

Abstract The aim of this study was to analyze the association between different sedentary behaviors and high blood pressure in adolescent boys and girls. We conducted a cross-sectional study with 6,264 Brazilian adolescents (14 to 19 years old). Demographic data, obesity indicators and blood pressure, were evaluated. Time spent in the sedentary behaviors (television viewing, playing video games, using the computer, non-screen sitting and, total time sitting) were also assessed. The girls spent more time watching television than boys, whereas boys spent more time using computers and video games (12.7% vs. 7.4%, p < 0.001) than girls. Boys who watched more than four hours of television presented higher odds to give high blood pressure after adjustments for physical activity level, body mass index, age and educational level of mother (OR = 2.27, p < 0.001). In girls, we did not find a relation between sedentary behaviors and high blood pressure (p > 0.05). Television viewing time is associated with high blood pressure only boys. So, reduce this sedentary behavior, stimulating physical activities, might be essential to health, principally for male adolescents.

scholarly journals Physical activity level in people with high blood pressure

2009 ◽  
Vol 17 (4) ◽  
pp. 462-467 ◽  
Author(s):  
Larissa Castelo Guedes Martins ◽  
Nirla Gomes Guedes ◽  
Iane Ximenes Teixeira ◽  
Marcos Venícios de Oliveira Lopes ◽  
Thelma Leite de Araujo
Keyword(s):  
Physical Activity ◽  
Blood Pressure ◽  
High Blood Pressure ◽  
Physical Activity Level ◽  
International Physical Activity Questionnaire ◽  
Cross Sectional Study ◽  
Activity Level ◽  
Cross Sectional ◽  
Educational Levels ◽  
Activity Questionnaire

This study aimed to analyze the level of physical activity for people with high blood pressure cared for in a health center. This cross-sectional study was conducted with 310 individuals between 18 and 69 years of age through the International Physical Activity Questionnaire (IPAQ). The majority (80%) of participants presented low or moderate levels of physical activity. The analysis of association between sociodemographic variables and physical activity level revealed that older men from the interior of the state with higher educational levels have a greater chance of exhibiting lower levels of physical activity. The logistic regression model revealed that origin, schooling and diabetes are predictors of low physical activity level. The conclusion is that part of the sample does not match the desirable profile to practice regular physical activity.

scholarly journals Clinical differences between eosinophilic and non-eosinophilic acute exacerbation of chronic obstructive pulmonary disease (AECOPD), a multicenter cross-sectional study

2020 ◽  
Author(s):  
Guangming Dai ◽  
Yajuan Ran ◽  
Jiajia Wang ◽  
Xingru Chen ◽  
Junnan Peng ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Demographic Data ◽  
Univariate Analysis ◽  
Underlying Disease ◽  
Cross Sectional Study ◽  
Chronic Obstructive ◽  
Multiple Logistic Regression ◽  
Sectional Study ◽  
Laboratory Findings ◽  
Cross Sectional

Abstract Background AECOPD is highly heterogeneous with respect to etiology and inflammation. COPD with higher blood eosinophils is associated with increased readmission rates and better corticosteroid response. However, the clinical features of eosinophilic AECOPD aren’t well explored. Then, the aim of this study was to investigate the clinical differences between eosinophilic and non-eosinophilic AECOPD. Methods A total of 643 AECOPD patients were enrolled in this multicenter cross-sectional study. Finally, 455 were included, 214 in normal eosinophils AECOPD (NEOS-AECOPD) group, 63 in mild increased eosinophils AECOPD (MEOS-AECOPD) group, and 138 in severe increased eosinophils AECOPD (SEOS-AECOPD) group. Then, demographic data, underlying diseases, symptoms, and laboratory findings were collected. Multiple logistic regression was performed to identify the independent factors associated with blood EOS. Correlations between blood EOS and its associated independent factors were evaluated. Results The significant differences in 19 factors, including underlying disease, clinical symptom, and laboratory parameters, were identified by univariate analysis. Subsequently, multiple logistic regression revealed that lymphocytes%, neutrophils% (NS%), procalcitonin (PCT), and anion gap (AG) were associated with blood EOS in AECOPD. Both blood EOS counts and EOS% significantly correlated with lymphocytes%, NS%, PCT, and AG. Conclusions The blood EOS was independently associated with lymphocytes%, NS%, PCT, and AG in AECOPD patients. Lymphocytes% was lower, and, NS%, PCT, and AG were higher in eosinophilic AECOPD. Our results indicate that viral dominant infections probably were the major etiology of eosinophilic AECOPD. Non-eosinophilic AECOPD was more likely associated with bacterial dominant infections. The systemic inflammation in non-eosinophilic AECOPD was more severe.

scholarly journals Liver Function, Leucocyte, and Blood Pressure Levels with Acute Stroke Functional Outcomes

2021 ◽  
Vol 16 (3) ◽  
pp. 417-427
Author(s):  
Destika Fahrina ◽  
Mahmuddin Mahmuddin ◽  
Irina Kemala Nasution ◽  
Yuneldi Anwar
Keyword(s):  
Blood Pressure ◽  
Liver Function ◽  
Acute Stroke ◽  
Functional Outcome ◽  
Demographic Data ◽  
Cross Sectional Study ◽  
Serum Glutamic Oxaloacetic Transaminase ◽  
Cross Sectional ◽  
Indirect Bilirubin ◽  
The Relationship

Several studies have shown that there is an increase in bilirubin levels, leukocytes, and blood pressure in acute phase strokes. The purpose of this study was to determine the relationship between liver function levels, leucocytes, and blood pressure with the functional outcome of acute stroke. The method was a cross-sectional study with a sample size of 30 people who were selected by consecutive non-random sampling method, clinically proven acute stroke patients, and computed tomography (CT) scan. They were studied at the General Hospital of the Adam Malik Center. Demographic data were analyzed using descriptive statistics. The results showed that all subjects did not differ in terms of demographic characteristics. This study concluds that there is no relation between liver function (total bilirubin, direct bilirubin, indirect bilirubin, serum glutamic oxaloacetic transaminase [AST], serum glutamic pyruvic transaminase [SGPT], alkaline phosphatase [ALP]), leukocytes, and blood pressure with acute stroke functional outcome. The functional outcome in acute hemorrhagic stroke is worse than acute ischemic stroke. Higher levels of liver function, leucocytes, and blood pressure were found in patients with the worse functional outcome though not significantly associated.

scholarly journals Epidemiology of high blood pressure among the Kaingang people on the Xapecó Indigenous Land in Santa Catarina State, Brazil, 2013

2015 ◽  
Vol 31 (2) ◽  
pp. 331-344 ◽  
Author(s):  
Deise Bresan ◽  
João Luiz Bastos ◽  
Maurício Soares Leite
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Body Mass Index ◽  
High Blood Pressure ◽  
Demographic Data ◽  
High Body Mass Index ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Indigenous Land

This cross-sectional study describes the prevalence of high blood pressure (HBP; measured at one setting, and suggestive of a clinical diagnosis of arterial hypertension) and mean systolic blood pressure (SBP) and diastolic blood pressure (DBP) and their associations with socio-demographic and anthropometric variables among 355 Kaingang adults (≥ 20 years) on the Xapecó Indigenous Land in Brazil. Weight, height, waist circumference (WC), SBP, and DBP were measured and socio-demographic data were collected. Prevalence of HBP was 53.2% (95%CI: 45.3; 61.1) in men and 40.7% (95%CI: 33.8; 47.6) in women. In women, age and WC were directly associated with HBP; age was associated with SBP and schooling with DBP. In men, HBP was statistically associated with high body mass index (BMI) and tile floor in the home (as a socioeconomic proxy); BMI and WC were associated with SBP; BMI and WC were associated with DBP. The study highlights the need for measures to control risk factors for HBP, especially due to its relevance for cardiovascular diseases and their consequences.

scholarly journals Cardiovascular Risk Factors in Transgender Women Undergoing Long-Term Gender-Affirming Hormone Therapy: A Cross-Sectional Study

2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. A788-A789
Author(s):  
Leonardo A M Alvares ◽  
Lívia M Santos ◽  
Henrique A Ramos ◽  
Larissa G Rodeghel ◽  
Nathan B Cavenaghi ◽  
...  
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Hormone Therapy ◽  
Cross Sectional Study ◽  
Transgender Women ◽  
Activity Level ◽  
Sectional Study ◽  
Cross Sectional ◽  
Statistical Point

Abstract Introduction: Few data of long-term outcomes of cardiovascular (CVRF) risk factors of transgender women (TW) undergoing gender-affirming hormone therapy (GAHT) are available. Objectives: Evaluate CV risk factors after long-term GAHT in TW. Methods: A cross-sectional study was carried out with 8 TW (average age of 34.0 ±4.8 yo), 8 matched CM and 8 CW on age, body mass index (BMI) and activity level. All TW were non-gonadectomized subjects and were in estrogen [(E); transdermal estradiol (n=2), oral estradiol (n=3) and conjugated estrogen (n=3)] plus cyproterone acetate (CA) (n=8) therapy in an average time of 15.6 ±8.7 years. Results: Total Testosterone (ng/dL) level of TW, CW and CM were 83,5 (range 12,0-637,0), 20,5 (range 12,0-41,0) and 480,5 (range 264,0-843,0), respectively. It was similar between TW and CW (p=0,7284) and different in the comparison TWvsCM (p=0,0325). In TW group, the median of blood glucose was 84 mg / dL, HBA1c 5.1%, total cholesterol 146 mg / dL, HDLc 43 mg / dL, LDLc 89 mg / dL and triglycerides 81.5 mg / dL. In the comparison with other groups, there was no difference from the statistical point of view. It is necessary to emphasize the HDLc of TW (43 mg/dL) which was exactly the same of CM (p&gt;0,999) and lower than CW (60 mg/dL)(p=0,0720). Systolic Blood Pressure (SBP)(mmHg) of TW (126±13) was higher than that of CW (95±11;p&lt;0.001) and equal to that of CM (115±9;p=0.1489). Regards Diastolic Blood Pressure (DBP) (mmHg), the medians of TW, CW and CM were 80, 60 and 80, respectively, and in the comparison TWxCW p = 0.0070 and TWxCM p&gt; 0.9999. Discussion: Youth TW (16.3 ± 1.4 yo) taking an average estradiol dose of 1.5 ± 1.0 mg/day, with an average AGHT duration of 12.3 ± 9.9 months matched to controls on age and BMI did have higher HDL than CW and TW participants were more insulin resistant than CM. About SBP of that youth TW (107 ± 12), it was lower than CW 113 ± 7 (p&gt;0,05) and CM 116 ± 8 (p&lt;0,001). Other previous study showed that after 6 months of estradiol use, in doses ranging from 2 to 8 mg daily glucose enhanced 6 mg/dL (from 86 to 92) as well as TC from 170 to 178 mg/dL, HDLc from 50 to 54 mg/dL, TGL from 102 to 115 mg/dL, and LDL did not change (93), while a systematic review and meta-analysis showed increased only in TG levels. SBP and DBP increased on average of 7,2 mmHg and 5,7 mmHg, respectively. Conclusion: Metabolic findings observed after the first few months of TW GAHT appear to remain at long term, except for HDLc. SBP and DBP appear to increase in the long term, after a drop initially observed.

scholarly journals The quality of patients’ self-blood pressure measurements: a cross-sectional study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Katarzyna Nessler ◽  
Anna Krztoń-Królewiecka ◽  
Anna Suska ◽  
Mitchell R. Mann ◽  
Michał B. Nessler ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Primary Healthcare ◽  
Demographic Data ◽  
Measurement Techniques ◽  
Healthcare Setting ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Hypertensive Patients ◽  
The Common

Abstract Background The accurate and independent measurement of blood pressure (BP) by patients is essential for home BP monitoring (HBPM) and determining the quality of hypertension (HTN) control. This study aimed to evaluate the BP self-measurement techniques of hypertensive patients and their accuracy in accordance with established guidelines. We sought to identify the common errors that patients make and suggest improvements that can be implemented in the primary healthcare setting to increase the reliability of HBPM conducted by hypertensive patients. Methods One hundred patients diagnosed with HTN completed a questionnaire inquiring about their health and demographic data and BP monitoring practices. Patients were then observed and filmed while measuring their BP on their own devices in five primary healthcare centres in Kraków, Poland. The correctness of their techniques was assessed in accordance with the European Society of Hypertension guidelines on HBPM. Results Only 3% of patients measured their BP without error; 60% made three or more errors. The most frequent error, made by 76% of subjects, was incorrect sphygmomanometer cuff placement (above or below heart level, or/and the indicator mark was not aligned with the brachial artery). Regarding patients’ previous instruction for the correct use of their devices, 36% of patients referred to their monitor’s user manual, 22% did not receive any prior assistance, and only 29% were adequately counselled by physicians on how to measure their BP correctly. Conclusions Our findings suggest that primary healthcare physicians and their personnel often do not adequately instruct patients on how to measure their BP correctly. Therefore, healthcare systems must provide patients with more adequate training and reference materials on the best practices of BP monitoring.

Sign in / Sign up

Export Citation Format

Share Document