scholarly journals Evaluation of Methadone Consumption Rate Based on Post-mortem Toxicology Examinations in Cases of Drug-related Deaths in Iran: 2015-2017

2021 ◽  
Vol 15 (3) ◽  
pp. 143-150
Author(s):  
Jalil Hasani ◽  
◽  
Davood Mirtorabi ◽  
Mohammad Reza Ghadirzadeh ◽  
Amirhossein Mahdavi ◽  
...  

Background: Given the increasing prevalence of methadone overdose and the growing number of deaths in Iran, the present study was conducted to determine the mortality rate of methadone detected in the cadavers brought to the Forensic Medicine Organization between 2015 and 2017. Methods: This cross-sectional study was performed on 7,486 cases of substance abuse deaths registered in the Forensic Medicine Organization during 2015-2017. In order to investigate the drug abuse, samples collected from the cadavers were initially examined for their drug contents, such as methadone, by standard screening methods and then confirmed by Thin Layer Chromatography (TLC). Using two checklists, the information collected about each cadaver consisted of the identity, autopsy and laboratory data. After data collection, they were entered into the Stata software version 14 MP. Results: The cadavers’ mean age was 36.6±12.6 years. Over the 3-year duration of the study, the standardized mortality rate increased from 35 to 39 cases per million per year. Of these cases, 6066 were randomly assigned to toxicology, 50.1% had used methadone one month before their death. Approximately 75% of the methadone abusers had taken another drug simultaneously, mostly morphine or methamphetamine. Conclusion: Considering the relatively high prevalence of methadone detected post-mortem, monitoring for methadone entry into public market and identifying the death-related factors in the drug abusers are considered as significant measures to improve upon the current alarming situation in the Iranian society.

Author(s):  
Mehrdad Mirzarahimi ◽  
Afsaneh Enteshari- Moghaddam ◽  
Sepideh Khademi

Background: Neonatal mortality rate (NMR) is one of the important parameters in assessing quality of life in societies. NMR are often used as a standard index for evaluation health, education and social systems, nutritional status and health programs for neonates in countries and the first step in reducing mortality rate and promoting the level of this indicator is to identify the causes of mortality. Therefore, this study was conducted to determine the NMR in new born infants admitted to the ICU of Ardabil city hospitals.Methods: This study was a descriptive cross-sectional study that has been done on 184 dead neonates in Ardabil city hospital during 2016-2017. The necessary information was extracted from the hospital records of neonates and entered in a provided checklist and then analyzed by statistical methods such as tables in SPSS version 19.Results: The mortality rate of hospitalized infants in this research was 6.6%. Of all patients, in 65.2% CBC were impaired and 58.7% of patients had impaired serologic and biochemical tests. 68.5% of patients had prematurity, 62.5% RDS and 20.7% had congenital anomalies.Conclusions: Prematurity, RDS and congenital anomalies are the most important causes of NMR and we should programing to decreasing the NMR rate in future.


2019 ◽  
Vol 31 (Number 2) ◽  
pp. 32-35
Author(s):  
Z Hossain ◽  
M Mannan ◽  
MMU Islam ◽  
HM Kabir ◽  
S Mahmud

Homicide means killing one human being by another humafilt is a global problem and has significant consequence for both social and economic security of the people as well as national development This study warmed to describe patterns of the homicidal behavior in a major metropolitan area. Dhaka city and the relationships among socio-demographic characteristics. This was a cross-sectional study during the period of July 2017 to June 2018 in the Department of Forensic Medicine, Dhaka Medical College. A total number of 935 cases wereautopsied during the period,of which 319 cases were included in the study as homicidaldeath. All the inquest reports and the challan were read through along with post-mortem reports during the study period. The data were collected during the autopsy as well as from the registration books (Govt. records.) in the department of Forensic Medicine, Dhaka Medical College.Out of 319 homicidal death, 227cases were above the age of 30 years (71.15 % of the total cases),233 cases were male (73.04 %) and 86 were female (26.95 %) whereas considering religion, the majority were Muslim 287 in number (89.20%) and the rest were other religion. According to the types of wound 198 cases were stab and eta-throat, 81 cases were strangulation, 32cases were firearm injury & the 08 cases were suffocated The majority of deceased resulting from stab and cut-throat injuries and those were above 30 years of age group. The most of homicidal death occurred among the young age group which is very alarming to the society and for the nation. So, we should be aware enough to prevent such cases.


2022 ◽  
Author(s):  
Serap Şimşek-Yavuz ◽  
Gülşah Tunçer ◽  
Özlem Altuntaş Aydın ◽  
Mehtap Aydın ◽  
Filiz Pehlivanoğlu ◽  
...  

Abstract PurposeCOVID-19 vaccines have been shown to be highly effective; however, vaccine breakthrough infections resulting from hospitalization may still occur in a small percentage of vaccinated individuals. We investigated whether the clinical and microbiological features and outcomes were different between hospitalized COVID-19 vaccinated and unvaccinated COVID-19 patients.MethodsThis multicentre, prospective, cross-sectional study was performed between April and June 2021. All hospitalized COVID-19 patients who previously had at least one dose of Coronavac were included in the study, along with some unvaccinated patients. All epidemiologic, clinical and laboratory data of the patients were recorded and compared between the vaccinated and unvaccinated individuals.ResultsThere were 69 fully Coronavac vaccinated and 175 unvaccinated patients. All breakthrough infections occurred in the first 3 months of vaccination. Fully vaccinated patients were older and had more comorbidities than unvaccinated patients (p<0.05). There were minor differences between the groups in the symptoms, physical and laboratory findings, anti-spike IgG positivity rate, mean anti-SARS-CoV-2 S antibody level, and severity of COVID-19. The mortality rate of fully vaccinated patients was higher than the mortality rate in unvaccinated patients; however, vaccination was not an independent risk factor for mortality.ConclusionsHospitalized patients with breakthrough COVID-19 after Coronavac vaccination were usually older with comorbidities. The severity and clinical outcomes of these cases were similar to those of unvaccinated patients. Our findings suggest that the immune response elicited by Coronovac could be insufficient to prevent COVID-19-related severe disease and death within 3 months of vaccination among elderly people with comorbidities.


1970 ◽  
Vol 40 (1) ◽  
pp. 18-21 ◽  
Author(s):  
MN Hossain ◽  
Z Rahman ◽  
S Akhter

A cross sectional study was carried out at the department of Forensic Medicine in Dhaka Medical College during the period of January 2008 to December 2009. Data were collected from 3rd copy of the post mortem reports which were preserved in the department of Forensic Medicine with the verbal consent of the doctors who performed autopsy report. During this period total 5114 autopsies were conducted. Out of this 970 cases (19%) were suicidal in nature. It was noticed that all suicidal deaths occurred from 10 years to all age group respectively, but top amongst age group of suicidal deaths occurred in between 21 to 30 years of people. Suicidal deaths are more common in female than male. Suicidal deaths due to hanging is highest, next common causes of death due to organophosphorus compund poisoning. Suicidal deaths by hanging is more in female than male but in poisoning cases male are more lvictimised than female. Objectives of our study are to see the occurrence and methods of suicidal death. DOI: http://dx.doi.org/10.3329/bmj.v40i1.9957 BMJ 2011; 40(1): 18-21


2015 ◽  
pp. 153-161
Author(s):  
Thi Bach Yen Hoang ◽  
Thi Hai Pham ◽  
Dinh Tuyen Hoang ◽  
Thi Huong Le ◽  
Van Thang Vo

Food consumption survey is an essential parts of nutrition surveys. It helps to determine the type and quantity of food consumed, assessing the balance of the diet, the relationship between nutrient intake and health, diseases, and economic status, culture society... There are many methods to investigate food consumption. 24-hour food record is a method that record all food consumed by the subject during previous 24 hours. Using this method in chidren helps to assess the their diet to see if it responses the demand in order to have proper nutrition. Objectives: 1. Calculating the number of each food groups consumed within 24 hours of children 1 to 5 years in Phuoc Vinh ward, Hue City; 2. Assessing the quality of their diet and some related factors. Methodology: A cross-sectional study was implemented on 200 pairs of children aged 1 to 5 and parents or caregivers living in Phuoc Vinh ward, Hue city and some related factors. Results: 82% of the children’s diets covered 4 food groups. Prevalence of glucide, protein, lipide out of the total energy intake were 44.1%, 19.5%, 36.3% respectively within group of 12-<48 months and 50%, 19.5%, 30.6% respectively within group of 48-<72 months. Total energy and protein intake were higher than demanded (p <0.05) while glucide and lipide were lower than demanded (p <0.05). Economical status of family was significant associated with variety of food (all 4 food groups) in the diet of children (p <0.05) and total energy consumed (p <0.05). Conclusion: The children did not have proper nutrition so further research need to be implemented to have suitable interventions. Key words: 24 hours food records, children aged 1 to 5, Hue city.


2012 ◽  
pp. 129-134
Author(s):  
Thi Lan Tran ◽  
Thi Huong Le ◽  
Xuan Ninh Nguyen

Objectives: Assess the nutritional status, worm infection status and some related factors among children aged 12-36 months of Dakrong district, Quang Tri province. Subject and method: A cross sectional study was carried out in 2010, in 680 children aged 12-36 months in 4 communes of Dakrong district, Quang Tri province. Results: The malnutrition rate was 55.0% for underweight, 66.5% for stunting and 16.2% for wasting. The prevalence of malnutrition increases by age group. The prevalence of worm infection was 31.6%, the highest prevalence was belong to Ascaris infection (24.6%), followed by Hookworm and Trichuris (6.5% and 6.2%, respectively). The prevalence of worm infection among children under two is very high (27.0%). The prevalence of worm infection was distributed quite equally between the malnutrition children group and normal children group. Recommendation: Early deworming forchildren from 12 months should be considered as important strategy against the malnutrition of children in Dakrong district, Quang Tri province


BMJ Open ◽  
2019 ◽  
Vol 9 (11) ◽  
pp. e029931 ◽  
Author(s):  
Akihiko Narisada ◽  
Kohta Suzuki

ObjectiveTo investigate the associations among procrastination (time inconsistency), work environment and obesity-related factors in Japanese male workers.DesignCross-sectional study.SettingData were collected at two work sites of Japanese electronics manufacturing company in 2015.Participants795 full-time male workers in a Japanese electric company, aged 35–64 years, who underwent health checkups in 2015.Main outcome measuresBody mass index (BMI), adult weight change, obesity (BMI ≥25 kg/m2), adult weight gain over 10 kg (AWG10) and metabolic syndrome (MetS). Multivariable linear and logistic regression analyses were performed to assess the associations of procrastination assessed by using a one-item questionnaire and white-collar and blue-collar work with obesity-related factors.ResultsWhite-collar workers with high procrastination levels showed positive associations with BMI (B: 0.75, 95% CI 0.06 to 1.44) and adult weight change (B: 1.77, 95% CI 0.26 to 3.29), and had increased odds of AWG10 (OR: 1.85, 95% CI 1.04 to 3.29) and MetS (OR: 2.29 95% CI 1.18 to 4.44) after adjustment for age, education, work-related factors and lifestyle factors. However, such positive associations were not observed among blue-collar workers.ConclusionsProcrastination and white-collar work might have a joint effect on weight gain during adulthood and consequential obesity.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Hongyan Wang ◽  
Xiaoling Dai ◽  
Zichuan Yao ◽  
Xianqing Zhu ◽  
Yunzhong Jiang ◽  
...  

Abstract Introduction To explore the prevalence of depressive symptoms and the associated risk factors in frontline nurses under COVID-19 pandemic. Methods This cross-sectional study was conducted from February 20, 2020 to March 20, 2020 and involved 562 frontline nurses. The effective response rate was 87.68%. After propensity score matched, there were 498 participants left. Extensive characteristics, including demographics, dietary habits, life-related factors, work-related factors, and psychological factors were collected based on a self-reported questionnaire. Specific scales measured the levels of sleep quality, physical activity, depressive symptoms, perceived organization support and psychological capital. Adjusted odds ratios and 95% confidence intervals were determined by binary paired logistic regression. Results Of the nurses enrolled in the study, 50.90% had depressive symptoms. Three independent risk factors were identified: poor sleep quality (OR = 1.608, 95% CI: 1.384–1.896), lower optimism of psychological capital (OR = 0.879, 95% CI: 0.805–0.960) and no visiting friend constantly (OR = 0.513, 95% CI: 0.286–0.920). Conclusions This study revealed a considerable high prevalence of depressive symptoms in frontline nurses during the COVID-19 outbreak, and identified three risk factors, which were poor sleep quality, lower optimism of psychological capital, and no visiting friend constantly. Protecting mental health of nurses is important for COVID-19 pandemic control and their wellbeing. These findings enrich the existing theoretical model of depression and demonstrated a critical need for additional strategies that could address the mental health in frontline nurses for policymakers.


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