scholarly journals Postpartum Thyroiditis: A Case Report

2021 ◽  
Vol 3 (2) ◽  
pp. 42-47
Author(s):  
Jessica Patricia Pangaribuan ◽  
Santi Syafril
Keyword(s):  
Good Prognosis ◽  
Postpartum Women ◽  
Thyroid Follicle ◽  
Case Presentation ◽  
Postpartum Thyroiditis ◽  
Second Child ◽  
The World ◽  
Hoarse Voice ◽  
Hematologic Examination ◽  
Repeated Evaluation

ABSTRACT: Background: Postpartum thyroiditis (PPT) is a thyroid dysfunctionn syndrome which is temporary or permanent that occurs 1 year after giving birth or abortion. The occurrence of postpartum thyroiditis is 5 – 10% of postpartum women in the world. It is caused by an inflammation of the thyroid gland which leads to a destruction of the thyroid follicle and proteolysis of thyroglobulin. Case presentation: A woman, 31 years old, was admitted to the hospital complaining an enlargement on her neck. The patient said her the enlargement keeps getting larger and she also complained a feeling of something stuck in the throat. The patient also complained a hoarse voice. The patient has just given birth of her second child 5 months ago. From a hematologic examination, radiologic, and blood culture, the patient was diagnosed with Postpartum Thyroiditis. The patient was given Euthyrox therapy and will undergo repeated evaluation after 1 months of the therapy. Conclusion: We reported a case of Postpartum Thyroiditis that was treated comprehensively, and showed a good prognosis.  

scholarly journals Cerebral venous thrombosis in a patient with Down syndrome and coronavirus disease 2019: a case report

2021 ◽  
Vol 15 (1) ◽  
Author(s):  
Henry Robayo-Amortegui ◽  
Natalia Valenzuela-Faccini ◽  
Cesar Quecano-Rosas ◽  
Darlyng Zabala-Muñoz ◽  
Michel Perez-Garzon
Keyword(s):  
Risk Factors ◽  
Down Syndrome ◽  
Case Report ◽  
Venous Thrombosis ◽  
Cerebral Venous Thrombosis ◽  
Epidemiological Data ◽  
Thromboembolic Disease ◽  
Hispanic Woman ◽  
Case Presentation ◽  
The World

Abstract Background The new coronavirus disease 2019 pandemic has spread throughout most of the world. Cerebral venous thrombosis is a rare thromboembolic disease that can present as an extrapulmonary complication in coronavirus disease 2019 infection. Case presentation We report the case of a Hispanic woman with Down syndrome who has coronavirus disease 2019 and presents as a complication extensive cerebral venous thrombosis. Conclusions Cerebral venous thrombosis is a rare thromboembolic disease that can present as an extrapulmonary complication in coronavirus disease 2019 infection. In the absence of clinical and epidemiological data, it is important to carry out further investigation of the risk factors and pathophysiological causes related to the development of cerebrovascular thrombotic events in patients with Down syndrome with coronavirus disease 2019 infection.

scholarly journals Mucosal Immunity and Liver Metabolism in the Complex Condition of Lactation Insufficiency

2020 ◽  
Vol 36 (4) ◽  
pp. 582-590
Author(s):  
Courtney B. Betts ◽  
Alexandra Quackenbush ◽  
Weston Anderson ◽  
Nicole E. Marshall ◽  
Pepper J. Schedin
Keyword(s):  
Clinical Practice ◽  
Mucosal Immunity ◽  
Scientific Inquiry ◽  
World Health ◽  
Postpartum Women ◽  
Human Breast ◽  
Reproductive State ◽  
Growth Requirements ◽  
State Dependent ◽  
The World

Lactation insufficiency is variously defined and includes the inability to produce milk, not producing enough milk to exclusively meet infant growth requirements, and pathological interruption of lactation (e.g., mastitis). Of women with intent-to-breastfeed, lactation insufficiency has been estimated to affect 38%–44% of newly postpartum women, likely contributing to the nearly 60% of infants that are not breastfed according to the World Health Organization’s guidelines. To date, research and clinical practice aimed at improving feeding outcomes have focused on hospital lactation support and education, with laudable results. However, researchers’ reports of recent rodent studies concerning fundamental lactation biology have suggested that the underlying pathologies of lactation insufficiency may be more nuanced than is currently appreciated. In this article, we identify mucosal biology of the breast and lactation-specific liver biology as two under-researched aspects of lactation physiology. Specifically, we argue that further scientific inquiry into reproductive state-dependent regulation of immunity in the human breast will reveal insights into novel immune based requirements for healthy lactation. Additionally, our synthesis of the literature supports the hypothesis that the liver is an essential player in lactation—highlighting the potential that pathologies of the liver may also be associated with lactation insufficiency. More research into these biologic underpinnings of lactation is anticipated to provide new avenues to understand and treat lactation insufficiency.

scholarly journals Nevoid melanoma of the vagina: report of one case diagnosed on thin layer cytological preparations

CytoJournal ◽  
2007 ◽  
Vol 4 ◽  
pp. 14 ◽  
Author(s):  
Franco Fulciniti ◽  
Paolo Antonio Ascierto ◽  
Ester Simeone ◽  
Patrizia Bove ◽  
Simona Losito ◽  
...  
Keyword(s):  
Thin Layer ◽  
World Literature ◽  
Primary Melanoma ◽  
Sampling Procedure ◽  
Amelanotic Melanoma ◽  
Immunocytochemical Study ◽  
Case Presentation ◽  
The World ◽  
Cytological Sample

Background Primary melanoma of the vagina is an extremely rare neoplasm with approximately 250 reported cases in the world literature [1–4]. In its amelanotic variant this lesion may raise several differential diagnostic problems in cytological specimens [5]. In this setting, the usage of thin layer cytopathological techniques (Liquid Based Preparations = LBP) may enhance the diagnostic sensitivity by permitting immunocytochemical study without having to repeat the sampling procedure. The aim of this paper is to describe the cytomorphological presentation of primary vaginal melanoma on LBP since it has not previously been reported up to now, to our knowledge. Case presentation a 79-y-o female complaining of vulvar itching and yellowish vaginal discharge underwent a complete gynaecological evaluation during which a LBP cytological sample was taken from a suspicious whitish mass protruding into the vaginal lumen. A cytopathological diagnosis of amelanotic melanoma was rendered. The mass was radically excised and the patient was treated with α-Interferon. Conclusion amelanotic melanoma may be successfully diagnosed on LBP cytological preparations. Thin layer preparations may enhance the diagnostic cytomorphological clues to its diagnosis and may permit an adequate immunocytochemical characterization of the neoplasm.

scholarly journals Pembrolizumab in FIGO IVB Verrucous Carcinoma of the Vulva: A Case Report

2021 ◽  
Vol 11 ◽  
Author(s):  
Yuhan Wang ◽  
Rongchun Lin ◽  
Bingzhong Zhang ◽  
Hui Zhou ◽  
Zhongqiu Lin ◽  
...  
Keyword(s):  
Vulvar Cancer ◽  
Verrucous Carcinoma ◽  
Gynecologic Cancer ◽  
Residual Tumor ◽  
Good Prognosis ◽  
Pelvic Cavity ◽  
Case Presentation ◽  
Radical Vulvectomy ◽  
Histopathological Studies

BackgroundVulvar cancer is the fourth most common gynecologic cancer, and prognosis is poor in advanced vulvar cancer patients. Treatment for advanced vulvar cancer has not been satisfactory. In this report, we firstly report a FIGO IVB vulva verrucous carcinoma patient who obtained good prognosis after systemic treatment.Case PresentationA patient was admitted to hospital due to her vulvar lesion persistent for past 14 years. The vulvar mass has widely invaded urethra, part of anus, the lower third of the vagina, bilateral superior and inferior branches of pubis, and bilateral internal and external muscles of obturator. Multiple metastatic lymph nodes were also found in the pelvic cavity. The histopathological studies confirmed vulvar verrucous carcinoma with a PD-L1 overexpression. After six courses of neoadjuvant chemotherapy and pembrolizumab, the patient underwent radical vulvectomy and achieved optimal cytoreduction. Postoperative pathology found no residual tumor. The patient then received one course of postoperative chemotherapy and pembrolizumab, underwent radiation therapy, and was disease free after 6 months follow-up.ConclusionOur individualized treatment strategy is successful. Pembrolizumab is safe and effective in the treatment of advanced vulvar verrucous carcinoma with PD-L1 overexpression.

scholarly journals Disseminated Intravascular Coagulation as the First Manifestation of Coronavirus Disease: Report of a Survived Deadly Case

2020 ◽  
pp. 1-5
Keyword(s):  
Computed Tomography ◽  
Vaginal Bleeding ◽  
Hypovolemic Shock ◽  
International Normalized Ratio ◽  
Coagulation Disorders ◽  
Spiral Computed ◽  
Case Presentation ◽  
The World ◽  
Life Threatening ◽  
Mucosal Bleeding

Introduction: Coronavirus disease 2019 (COVID-19), newly emerging in the world as a pandemic disease, can have rare extrapulmonary manifestations. Few studies have reported coagulation disorders, induced by coronavirus; however, hemorrhage is an extremely rare and life-threatening phenomenon in COVID-19. Case presentation: Herein, we present a 31-year-old woman referring with vaginal bleeding, melena, skin ecchymosis, mucosal bleeding, melena, hematuria, and hypovolemic shock. At our center, she was diagnosed as a case of severe internal hemorrhage due to ovulation site hemorrhage and underwent emergency surgery, complicated by prolonged international normalized ratio, which could be due to the presence of COVID-19 in the patient, detected by spiral computed tomography. Conclusions: This case showed the importance of examining COVID-19 in any patients referring to the hospital during the pandemic as well as paying greater attention to the effect of COVID-19 on coagulation disorders in these patients.

scholarly journals Neonatal oral teratoma: A case report

2021 ◽  
Vol 10 ◽  
pp. 24
Author(s):  
Helle Moustapha ◽  
Oumarou Habou ◽  
Kadre Alio Kadre Ousmane ◽  
Mahamoud Omid Ali Ada ◽  
Inoussa Daouda Bako ◽  
...  
Keyword(s):  
Oral Cavity ◽  
Germ Cells ◽  
Primordial Germ Cells ◽  
Germ Cell Tumors ◽  
Surgical Excision ◽  
Good Prognosis ◽  
Upper Lip ◽  
Complete Excision ◽  
Case Presentation ◽  
Irregular Mass

Background: Teratomas of the oral cavity are rare and can pose danger to a patient's life in terms of obstruction to the aerodigestive tract. These are the germ cell tumors that arise from all three layers of primordial germ cells. Case Presentation: A 2-day-old female neonate presented with a mass protruding from the oral cavity since birth with no significant antenatal history. Examination revealed a large (8 cm), firm, and irregular mass protruding from the oral cavity extending up to the inner surface of the upper lip and onto the gums, associated with cleft palate. Complete excision of the mass was done and histopathology confirmed the diagnosis. There were no postoperative complications. Conclusion: Oral cavity teratoma is a rare tumor with a good prognosis especially in its mature form. Surgical excision with multidisciplinary collaboration is needed in order to avoid any complications.

scholarly journals Unresectable primary hepatic adenosquamous carcinoma successfully treated with systemic and transcatheter hepatic arterial injection chemotherapies followed by conversion surgery: a case report and literature review

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Yusuke Watanabe ◽  
Akihiko Osaki ◽  
Kiwamu Kimura ◽  
Shunta Yakubo ◽  
Kenichi Takaku ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Liver Tumor ◽  
Needle Biopsy ◽  
Adenosquamous Carcinoma ◽  
Conversion Surgery ◽  
Dynamic Computed Tomography ◽  
Postoperative Adjuvant Chemotherapy ◽  
Case Presentation ◽  
The World ◽  
Node Metastases

Abstract Background Primary hepatic adenosquamous carcinoma (ASC) is a type of tumor that has the features of both adenocarcinoma and squamous cell carcinoma (SCC). The prognosis for patients with ASC is poor, as the chemotherapy has been ineffective so far. Case presentation Here, we report a case of a 62-year-old male patient who presented with high fever. The tumor marker levels were high, and abdominal dynamic computed tomography showed a liver tumor and distant lymph node metastases. Upon further investigation, needle biopsy of the liver tumor showed a primary hepatic SCC. Because the SCC was unresectable, the patient was treated with tegafur/gimeracil/oteracil (S-1) and transcatheter hepatic arterial injection (TAI) of cisplatin. After chemotherapy, a surgical resection performed on the remaining liver tumor, made the patient cancer-free. After the operation, the liver tumor was confirmed as primary hepatic ASC. Subsequently, the patient was administered postoperative adjuvant chemotherapy, which prevented its recurrence. Conclusions Due to the lack of an effective treatment for primary hepatic ASC, its prognosis is poor. Here, we suggest that a chemotherapy combination of 5-fluorouracil (S-1) and cisplatin along with conversion surgery might be an effective way for treating primary hepatic ASC. Our experience from this case shall be valuable to clinicians around the world involved in the treatment of primary hepatic ASC.

scholarly journals Epidemic prevention for coronavirus disease 2019 in Taiwan: A new perspective in emergency department

2020 ◽  
Vol 27 (6) ◽  
pp. 368-371
Author(s):  
Yang-Tse Lin ◽  
Wan-Ling Cheng ◽  
Chaou-Shune Lin ◽  
Chan-Peng Hsu
Keyword(s):  
United States ◽  
Emergency Department ◽  
Throat Swab ◽  
The United States ◽  
Epidemiological Investigation ◽  
Emergency Physicians ◽  
Prevention Strategies ◽  
Case Presentation ◽  
The World ◽  
New Perspective

Introduction: Coronavirus disease 2019 (COVID-19) has become a pandemic with millions of contagions all over the world. However, as of June 2020, relatively few indigenous cases have been identified in Taiwan. Case Presentation: A 34-year-old man presented to our emergency department with progressive rhinorrhoea, a sore throat, and recent travel to the United States (Texas) and Mexico. He was diagnosed with COVID-19 after a positive throat swab test. Even though he was not initially isolated, there was no cluster of infection identified after epidemiological investigation. Discussion: This case demonstrates Taiwan’s unique epidemic prevention strategy, including the utilization of face masks, compact screening indications, quarantine arrangements, and the effective disposition of confirmed cases. Conclusion: In addition to managing various emergent conditions, emergency physicians should prepare epidemic prevention strategies as soon as possible and provide frontline suggestions.

Synchronous Pancreatic and Pulmonary Metastases from Solitary Fibrous Tumor of the Pleura: Report of a Case

2017 ◽  
Vol 103 (1_suppl) ◽  
pp. S9-S11 ◽  
Author(s):  
Nicola Tamburini ◽  
Nicolò Fabbri ◽  
Gabriele Anania ◽  
Pio Maniscalco ◽  
Francesco Quarantotto ◽  
...  
Keyword(s):  
Solitary Fibrous Tumor ◽  
Pulmonary Metastases ◽  
Clinical Course ◽  
Good Prognosis ◽  
Pancreatic Metastasis ◽  
Case Presentation ◽  
First Case ◽  
Fibrous Tumor ◽  
Uncommon Tumor

Introduction Solitary fibrous tumor of the pleura is an uncommon tumor with an indolent course and a good prognosis after surgical resection. However, the tumor occasionally follows an unpredictable clinical course and malignant transformation has been reported to increase the rate of local recurrence. Solitary extrathoracic metastasis from solitary fibrous tumor of the pleura is an uncommon finding. Case Presentation In this case report we present the first case of a synchronous single pulmonary and pancreatic metastasis treated with minimally invasive surgery. Conclusions Pancreatic recurrence should be considered in the postoperative follow-up in patients with solitary fibrous tumor of the pleura.

scholarly journals A fatal case of chlorfenapyr poisoning following dermal exposure

2018 ◽  
Vol 26 (6) ◽  
pp. 375-378
Author(s):  
Sang-Kyoon Han ◽  
Seok-Ran Yeom ◽  
Sung-Hwa Lee ◽  
Soon-Chang Park ◽  
Hyung-Bin Kim ◽  
...  
Keyword(s):  
World Health Organization ◽  
Fatal Case ◽  
Dermal Absorption ◽  
World Health ◽  
Oral Ingestion ◽  
Case Presentation ◽  
Skin Exposure ◽  
The World ◽  
Main Activity ◽  
Health Organization

Introduction: Chlorfenapyr is a pyrrole-based pro-insecticide. The main activity of this agent is the inhibition of adenosine triphosphate synthesis, and it is used in agriculture to control several insects and mites resistant to carbamate, organophosphate and pyrethroid insecticide. The World Health Organization classifies this agent as a class II toxin (moderately hazardous). Case presentation: All previously reported cases of chlorfenapyr poisoning in humans occurred following oral ingestion except one case involving exposure to chlorfenapyr vapour. Discussion: In this report, we describe a case of chlorfenapyr intoxication after skin exposure in a 49-year-old patient who died 5 days after exposure. Conclusion: This case demonstrates that similar to oral ingestion, dermal absorption of chlorfenapyr may also be fatal.

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