scholarly journals Pengaruh Pemberian Ekstrak Etanol Herba Poguntano (Picria FelTerrae Lour.) Terhadap Profil Lipid Tikus Putih Jantan Dislipidemia

2018 ◽  
Vol 1 (1) ◽  
pp. 230-236
Author(s):  
Hendra Gunawan ◽  
Panal Sitorus ◽  
Rosidah Rosidah
Keyword(s):  
Lipid Profile ◽  
Total Cholesterol ◽  
Cholesterol Level ◽  
Triglyceride Level ◽  
Total Cholesterol Level ◽  
Blood Lipid ◽  
Male Rat ◽  
Control Group ◽  
Blood Lipid Profile ◽  
Used Cooking Oil

Latar Belakang: Dislipidemia adalah terjadinya kelainan metabolisme lipid, baik peningkatan maupun penurunan fraksi lipid dalam darah. Kelainan fraksi lipid yang utama adalah kenaikan kadar kolesterol total, kenaikan kadar LDL, kenaikan kadar trigliserida serta penurunan kadar HDL. Tingginya kadar lipid dalam darah dapat menyebabkan terjadinya aterosklerosis, yang ditandai dengan terdapatnya ateroma pada bagian intima arteri yang berisi kolesterol, zat lipoid, dan lipofag. Perkembangan lebih lanjut dari aterosklerosis ini akan menimbulkan komplikasi pada organ target diantaranya jantung dan otak. Tujuan Penelitian: Penelitian ini bertujuan untuk mengetahui pengaruh pemberian ekstrak etanol herba poguntano (EEHP) terhadap profil lipid tikus putih jantan dislipidemia (penurunan kadar kolesterol total, kadar trigliserida, kadar LDL dan peningkatan kadar HDL) serta terhadap proses aterosklerosis. Metode Penelitian: Penelitian ini dilakukan terhadap 30 ekor tikus putih jantan yang dibagi dalam 6 kelompok. Kelompok I sebagai kontrol normal, kelompok II sebagai kontrol negatif diberikan Na-CMC dosis 10 ml/kg bb, kelompok III sebagai kontrol positif diberikan atorvastatin dosis 2 mg/kg bb, kelompok IV, V, dan VI sebagai kelompok perlakuan diberi EEHP dosis 75, 150 dan 300 mg/kg bb. Hewan uji diberi induksi pakan tinggi lemak yang berupa campuran kuning telur puyuh, minyak jelantah, dan lemak sapi selama 14 hari berturut-turut untuk mendapatkan hewan uji dislipidemia yang dilanjutkan dengan treatment selama 14 hari berturut-turut. Pengukuran kadar profil lipid dilakukan pada hari ke-28. Hasil: Hasil analisis statistik menunjukkan bahwa EEHP dapat menurunkan kadar kolesterol total, kadar trigliserida, dan kadar LDL serta dapat meningkatkan kadar HDL secara nyata (p < 0,05). Kesimpulan: Berdasarkan hasil diatas, dapat disimpulkan bahwa EEHP mempuyai pengaruh terhadap profil lipid tikus dislipidemia (penurunan kadar kolesterol total, kadar trigliserida, kadar LDL dan peningkatan kadar HDL) serta dapat mencegah proses terjadinya aterosklerosis. Background: Dysplipidemia is a lipid metabolism dysfunctionsuch as the incline and the decline of blood lipid profile. The main abnormallipid fractionlevel are the increase of total cholesterol level, LDL level, and triglyceride and the decline of HDL level. The high level of blood lipid can cause atherosclerosis with the atheroma in arterial intima that contains cholesterol, lipoid, and lipophage. The advance stage of atherosclerosis can cause complications to target organs such as heart and brain. Objectives: This research aimed to evaluate the effects of herbapurganto (PiciaPicriaFelTerraeLour) ethanol extract on Lipid Profile of Dyspilidemic Male Rat(the decline of total cholesterol level, triglyceride level, LDL level, and the increase of HDL level) and also the atherosclerosis process. Research method: This research was conducted to 30male ratswhich dividedinto 6 groups. Group 1was served as the normal control, Group 2was servedas negative controls which were given 10 ml/kg bb Na-CMC , Group 3 was served as positive controls which were given 2 mg/kg bb of atorvastatin dosage, Group 4, 5, and 6 were served as the treatment group, and administered with EEHP at the dose of 75, 150, and 300 mg/kb bb . The test animals were fedwith high fatdiet using quail yolk, used cooking oil, and cow fat mixture for 14 days consecutively to obtain dyslipidemia subjects and continued with 14 consecutively treatment. The measure of lipid profile was conducted in the 28th day. Finding: The statistical analysis results indicated that EEHP could decrease the total of cholesterol level, triglyceride level, LDL level, and also it could increase the HDL level (p < 0.05). Conclusion: Based on the results, it could be concluded that EEHP haseffect towards dyslipidemia rat(the decline of total cholesterol level, triglyceride level, LDL level, and the increase of HDL level) and it could also prevent atherosclerosis.

scholarly journals Efek ekstrak daun sirsak (Annona muricata Linn) terhadap profil lipid tikus putih jantan (Rattus Norvegicus)

2014 ◽  
Vol 3 (1) ◽  
pp. 7-12 ◽  
Author(s):  
Indrawati Wurdianing ◽  
SA Nugraheni ◽  
Zen Rahfiludin
Keyword(s):  
Treatment Group ◽  
Lipid Profile ◽  
Total Cholesterol ◽  
Cholesterol Level ◽  
Ldl Cholesterol ◽  
Total Cholesterol Level ◽  
Wilcoxon Test ◽  
Control Group ◽  
Annona Muricata ◽  
The Mean

Background: Lipid profile effects is a risk factor for Coronary Heart Disease. Soursop leaves (Annona muricata L) isa traditional medicine plant containing metabolic compounds that contribute to the improvement of the lipid profile.Objective: To determine the effects of soursop leaves extract on lipid profile (total cholesterol, LDL cholesterol, HDLcholesterol and triglyceride).Methods: An experimental study using randomized pre-posttest with control group design. Sample consisted of 28 maleWistar rats, were divided into four groups. The control group (K) was only given High Fat High Cholesterol (HFHC)diet and treatment groups (P1, P2, P3) were given a HFHC diet plus Annona muricata L extract with doses of 100, 200and 300 mg/kgBB per day for 28 days respectively. Data were analyzed by Wilcoxon test, Kruskal-Wallis and MannWhitney.Results: The mean total cholesterol level significantly decreased in the treatment group P1 (p = 0.028) from 60.7 mg/dl(47.6-75.3) to 45.5 mg/dl (38.4-62.4). Mean HDL cholesterol level significantly increased in the treatment group P2(p=0.043) from 26.0 mg/dl (19.7-35.3) to 27.9 mg/dl (18.8-38.0). The mean levels of LDL cholesterol and triglyceridedecreased but not significantly.Conclusion: The administration of Annona muricata L extract can decrease total cholesterol and increase HDLcholesterol significantly.

Influence of Moderate, Daily Physical Activity On Body Composition and Blood Lipid Profile in Swedish Adults

2012 ◽  
Vol 9 (6) ◽  
pp. 867-874 ◽  
Author(s):  
Peter Pagels ◽  
Anders Raustorp ◽  
Trevor Archer ◽  
Ulf Lidman ◽  
Marie Alricsson
Keyword(s):  
Physical Activity ◽  
Energy Expenditure ◽  
Lipid Profile ◽  
Inverse Correlation ◽  
Blood Lipid ◽  
Daily Physical Activity ◽  
Moderate Intensity ◽  
Control Group ◽  
Brisk Walking ◽  
Blood Lipid Profile

Background:Health organizations suggest that adults ought to engage in at least 30 minutes of moderate-intensity daily physical activity. This study investigated the effects of a 30-minute single daily bout of brisk walking upon risk factors for coronary heart disease with blood lipid profile in particular.Methods:Thirty-three (25–45 y) adults, were randomly assigned into an exercise group (EG; n = 16, 9w) and a control group (CG; n = 17, 6w). The EG walked briskly 30 minutes daily during the 3-week test period. Compliance/adherence was maximal throughout the 3-week intervention due to stringent daily monitoring.Results:The EG showed a significant decrease in concentrations of low density lipoprotein cholesterol (LDL-C) and total cholesterol (TC) during the intervention period. A significant inverse correlation between Δ energy expenditure/day and Δ LDL-C (r = –0.39, P < .05) and an improvement in weight and BMI in the EG was found. Average steps during 30 minutes brisk walking bout was 3669 steps/bout generating a mean energy expenditure of 191 kcal/ bout.Conclusions:The most unique findings were that daily single bouts of moderate-intensity physical activity for 30 minutes, during 3 weeks, induced favorable effects upon body weight, BMI, and blood concentration of LDL-C and TC in healthy adults.

scholarly journals Clinical Investigations of the Effect of Citrus unshiu Peel Pellet on Obesity and Lipid Profile

2018 ◽  
Vol 2018 ◽  
pp. 1-6 ◽  
Author(s):  
Seongil Kang ◽  
Sangyeol Song ◽  
Joosang Lee ◽  
Hyekyung Chang ◽  
Sanghun Lee
Keyword(s):  
Lipid Profile ◽  
Total Cholesterol ◽  
Cholesterol Level ◽  
Weight Control ◽  
Large Scale ◽  
Total Cholesterol Level ◽  
Experimental Studies ◽  
Density Lipoprotein ◽  
Citrus Unshiu ◽  
The Impact

Objectives. Several experimental studies have reported antiobesity and lipid-improving effects of Citrus unshiu. However, clinical studies on its effects are lacking. This study was designed to evaluate the impact of Citrus unshiu peel pellet (CUPP) on obesity and lipid profile. Methods. For 118 patients with body mass index (BMI) > 23 who took Citrus unshiu peel pellet (CUPP) for 4 weeks in a Public Health Center, laboratory and biometric readings before and after CUPP administration were analyzed. Results. Mean age of these subjects was 53.8±10.6 years (range: 18-75 years). There were 88 (74.6%) females in the study sample (n = 118). A significant (p < 0.01) decrease in BMI from 27.47±2.24 to 27.27±2.22 was observed in all subjects after CUPP treatment and 65.3% (N = 77) of them lost 1.03±0.83 kg of weight after 4 weeks of treatment. Total cholesterol level was significantly (p < 0.01) decreased from 204.0±37.4 mg/dL to 193.5±36.5 mg/dL. Significant (p < 0.05) decreases in levels of low-density lipoprotein, cholesterol, and triglyceride were also observed. Conclusions. These results suggest that CUPP in practice could help weight control and improve total cholesterol level. Findings of this study provide clinical foundation for future large-scale trials to establish clinical benefits of CUPP.

scholarly journals Effect of dietary fatty acid on blood lipid profile and induced bacterial infection in rat

2015 ◽  
Vol 1 (2) ◽  
pp. 235-243
Author(s):  
Most Sumona Akter ◽  
Md Abu Yousuf ◽  
Md Yousuf Ali ◽  
Most Mahfuja Khatun ◽  
Sukumar Saha ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Lipid Profile ◽  
Density Lipoprotein ◽  
Blood Lipid ◽  
Blood Cholesterol ◽  
Control Group ◽  
Blood Lipid Profile ◽  
Bacterial Colony ◽  
Group A ◽  
Group B

Ground nut is one of the commonly used decorative nutritious relish seed around the world. Ground nut have hypocholesterolamic, hypoglycemic, hypolipidemic, anti-atherosclerotic, immune-modulatory and bacterial counting effects. In Bangladesh, limited research has so far been performed on the action of ground nut in biological system and its comparative efficacy with commercialized drugs that reduce blood cholesterol. The aim of this study was carried on the effects of PUFA on blood total cholesterol (TC), high density lipoprotein (HDL), low density lipoprotein (LDL) and triglyceride (TG) and against artificial inoculation (I/N) Staphylococcus aureus infection of experimental rat by feeding of ground nut. A total of fifteen long Evans rats (Rattus norvegicus) were used for this study. The rats were randomly divided into three equal groups (n=5) and numbered as A, B and C. Group A (control), Group B (50gm ground nut/ day/group), group C (100 gm ground nut/day/group). All groups were supplied with standard broiler pellet and fresh drinking water throughout the experimental period (January to June /2012). The blood samples were collected directly from the heart at the 1st and 60th day for biochemical test (TC, LDL, HDL and TG) and test was performed as per Memorial Diagnostic Centre, Charpara, Mymensingh. Staphylococcus aureus was cultured in nutrient broth and 100 µl of their culture was inoculated into the rats through intranasal route. Among all the treated groups, the rats of group C exhibited the lowest TC value, TG and LDL and reduced blood cholesterol significantly than (control group A) followed by group B. In bacteriological examinations, it was found that the number of bacterial colony lowest in group C in comparison with the group of A and B. From the present experiment, it can be assumed that PUFA has significant effect on blood lipid profile and against bacterial infection.Asian J. Med. Biol. Res. June 2015, 1(2): 235-243

scholarly journals Plasma lipid profile of mice fed diet supplemented with broiler fat

2014 ◽  
Vol 43 (1) ◽  
pp. 21-24 ◽  
Author(s):  
GB Das ◽  
ME Hossain ◽  
MA Akbar
Keyword(s):  
Lipid Profile ◽  
Palm Oil ◽  
Low Density Lipoprotein ◽  
Plasma Lipid ◽  
Density Lipoprotein ◽  
Dietary Treatment ◽  
Blood Lipid ◽  
Blood Cholesterol ◽  
Control Group ◽  
Blood Lipid Profile

This study was conducted with 180 female Swiss albino mice to examine the effects of supplementing broiler fat in the diets of mice on blood lipid profile. Twenty one days old mice were collected from ICDDRB, Mohakhali, Dhaka. They were randomly distributed in four groups having three replications each. Each replicate group had 15 mice. Results revealed that supplementation of broiler fat in mice diet significantly changed (p<0.05) triglyceride (TG) and low density lipoprotein (LDL) among groups. The control group (T0) had the highest level of cholesterol and LDL. Cholesterol, TG and LDL markedly increased (p<0.05) in all dietary treatment groups, while high density lipoprotein (HDL) significantly (p<0.01) decreased after supplementation of experimental diets. It was concluded that all the dietary treatments in general increased blood cholesterol, TG and LDL in mice fed broiler fat with different oil supplements. However, the soybean and palm oil group was comparatively better than other groups in respect of cholesterol, HDL and LDL at the blood lipid profile of mice. Therefore, it can be concluded that consumption of broiler fat with soybean and palm oil could be less harmful for mice.DOI: http://dx.doi.org/10.3329/bjas.v43i1.19380 Bang. J. Anim. Sci. 2014. 43 (1): 21-24

Effect of feeding synbiotic products on the serum cholesterol, HDL cholesterol and non- HDL cholesterol level of albino rats

2018 ◽  
Author(s):  
Rakesh Kumar ◽  
Binita Rani ◽  
Sonia Kumari ◽  
A K Jha
Keyword(s):  
Total Cholesterol ◽  
Cholesterol Level ◽  
Serum Cholesterol ◽  
Total Cholesterol Level ◽  
Hdl Cholesterol ◽  
Blood Cholesterol ◽  
Control Group ◽  
Albino Rats ◽  
Therapeutic Benefits ◽  
Effect Of Feeding

Considering the excellent bio-therapeutic benefits of Lactobacillus and Bifidobacterium, this study exploited the probiotic characteristics of Lactobacillus acidophilus-015, Lactobacillus casei-297 and Bifidobacterium bifidum-229 strains with natural prebiotic substances viz. banana powder, malto-dextrin and honey to produce synbiotic food formulations and to study the effect of feeding their on the cholesterol level (mg/dl) of albino rats. On the basis of the preliminary investigation, synbiotic products with 2% banana powder, with 2% malto-dextrin, with 3% honey and synbiotic product with 2% each of, banana powder and malto-dextrin and 1% of honey were selected for the investigation of the total cholesterol, HDL-cholesterol and non-HDL cholesterol. The products showed a significant decrease in total cholesterol level, however the control group receiving the cholesterol rich laboratory diet showed a significant increase (P LESS THEN 0.01) in the total cholesterol after 45 days of feeding. There was 25.81 to 45.05% reduction of serum cholesterol was observed in case of feeding synbiotic formulations. Increase in the HDL-cholesterol and decrease in the non-HDL cholesterol were also significant. Therefore, synbiotic formulation with all these three natural prebiotic have enhanced ability to decreased down the blood cholesterol level.

Krill oil to improve blood lipids status in advanced cancer patient with cachexia.

2012 ◽  
Vol 30 (15_suppl) ◽  
pp. e19634-e19634
Author(s):  
Roberto Serpe ◽  
Clelia Madeddu ◽  
Filomena Panzone ◽  
Giorgia Antoni ◽  
Maria Chiara Cau ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Lipid Profile ◽  
Total Cholesterol ◽  
Cancer Cachexia ◽  
Blood Lipid ◽  
Blood Levels ◽  
Krill Oil ◽  
Omega 3 ◽  
Blood Lipid Profile ◽  
Cholesterol Levels

e19634 Background: Cancer patients with cachexia symptoms often show a lipid profile disorder, consisting in severe hypertriglyceridemia due to increased circulating free fatty acids and variable total cholesterol levels, decreased activity of lipoprotein lipase and increased lipolysis, which is correlated with proinflammatory cytokines levels, particularly IL-6 and TNFα. Recent evidence further confirms impairment of adipose tissue metabolism in inflammatory condition like cancer cachexia. The aim of this study was to assess the effect of nutritional supplementation with Omega 3 fatty acids (EPA and DHA) in the form of Krill Oil, on main parameters of blood lipid profile and on IL-6 and TNFα blood levels. Methods: In 2011, 34 IV stage cachectic patients (M/F 20/14; age range 55-85 y) with cancer at different sites were enrolled. 21 healthy subjects were studied as controls. All patients had high blood tryglicerides, low total cholesterol levels , high levels of blood IL-6 and TNFα compared to controls. Patients received 3 capsules (3 g/day) of krill oil (Superba™ Krill Oil, Aker Biomarine, Norway), which is an oil extract from the crustacean krill (Euphausia Superba) which contains Omega-3 series unsaturated fatty acids in phospholipidic form, of which 98 % are EPA and DHA mainly in phospholipid form. Treatment duration was 2 months. Results: A significant reduction of tryglicerides blood levels (148.23 ± 88.06 vs 114 ± 55.8 mg/dl) and a significant improvement of HDL cholesterol (42.5 ± 15.6 vs 60.9 ± 12.3 mg/dl) and Total Cholesterol (135.6 ± 46.3 vs 159 ± 41.1 mg/dl) was observed after treatment. Cytokines Il-6 and TNFα blood levels did not change significantly after treatment Conclusions: Nutritional supplementation with krill oil showed a positive activity in the regulation of blood lipid profile, involving different metabolic and inflammatory pathways, probably mainly affecting hormone-sensitive lipase activity. Our data suggest that krill oil could be useful in multi-targeted combined pharmaco-nutritional approaches to treat cancer-cachexia. Additional phase III clinical studies are warranted.

scholarly journals Calcium intake and the associations with faecal fat and energy excretion, and lipid profile in a free-living population

2017 ◽  
Vol 6 ◽  
Author(s):  
Louise Kjølbæk ◽  
Janne K. Lorenzen ◽  
Lesli H. Larsen ◽  
Arne Astrup
Keyword(s):  
Lipid Profile ◽  
Total Cholesterol ◽  
Calcium Intake ◽  
Blood Lipid ◽  
Normal Weight ◽  
Urine Collection ◽  
Free Living ◽  
Blood Lipid Profile ◽  
Habitual Diet

AbstractThe aim of the present study was to investigate the associations between the habitual Ca intake and faecal fat and energy excretion as well as blood lipid profile in free-living normal-weight and overweight individuals. The participants were enrolled for an 8-d period where data from a 7-d diet registration (days 1–7), a 5-d faeces collection (days 3–7), a 2-d urine collection (days 5–7), and anthropometric measurements and a fasting blood sample (day 8) were collected. Analyses showed that dietary Ca intake (g/10 MJ per d) was positively associated with excretion of faecal fat (P = 0·004) and energy (P = 0·031) when adjusted for BMI, age, sex and intake of Ca-containing supplements. However, after adjustment for intake of fibre, the effect of Ca intake disappeared. Nevertheless, total cholesterol (CHOL) and LDL-CHOL concentrations were associated negatively with Ca intake (β −0·62 (95 % CI −0·96, −0·28) mmol/l, P < 0·001, and β −0·49 (95 % CI −0·78, −0·20) mmol/l, P = 0·001, respectively, per 1000 mg/10 MJ per d increase in Ca intake). In conclusion, incorporation of Ca-rich food products in a habitual diet was associated with reduced total CHOL and LDL-CHOL concentrations, which may lower the risk of CVD in the long term.

scholarly journals Modulation of placental protein expression of OLR1: implication in pregnancy-related disorders or pathologies

Reproduction ◽  
2008 ◽  
Vol 136 (4) ◽  
pp. 491-502 ◽  
Author(s):  
M Ethier-Chiasson ◽  
J-C Forest ◽  
Y Giguère ◽  
A Masse ◽  
C Marseille-Tremblay ◽  
...  
Keyword(s):  
Protein Expression ◽  
Lipid Profile ◽  
Total Cholesterol ◽  
Cholesterol Level ◽  
Plasma Cholesterol ◽  
Total Cholesterol Level ◽  
Low Density Lipoprotein ◽  
Ldl Receptor ◽  
Density Lipoprotein ◽  
Placental Protein

The lectin-like oxidized low-density lipoprotein (LDL) receptor-1 (OLR1) is a newly described receptor for oxidatively modified LDL. The human pregnancy is associated with hyperlipidemia and oxidative stress. It has been reported that modification in maternal lipid profile can induce disturbance during pregnancy. In this study, we have evaluated the expression protein level of OLR1 in human term placenta of women having plasma cholesterol level lower to 7 mM or higher to 8 mM and women of gestational diabetes mellitus (GDM) by western blot analysis. The present study demonstrates that the maternal lipid profile is associated with placental protein expression of OLR1. A significant increase in the protein expression of OLR1 was observed in placenta of women with elevated plasmatic total cholesterol level (>8 mM). In addition, the placental protein expression of OLR1 is increased in mothers having the highest pre-pregnancy body mass index (BMI) and low (<7 mM) plasmatic total cholesterol level at term. Interestingly, the placental protein expression of OLR1 is increased in the presence of GDM pregnancies compared with normal lipids level pregnancies, without the modification of mRNA expression. In conclusion, placental OLR1 protein expression is associated with maternal lipid profile, pre-pregnancy BMI, and pathology of GDM.

scholarly journals A Case-Control Study on Blood Lipid Profile in Patients with COVID-19

2021 ◽  
Author(s):  
Shahab Changaripour ◽  
Hosna Sarvazad ◽  
Maryam Barghi ◽  
Elham Sajadi ◽  
Mahdi Hashempour Sadeghian ◽  
...  
Keyword(s):  
Lipid Profile ◽  
Density Lipoprotein ◽  
Blood Lipid ◽  
Severe Form ◽  
Control Group ◽  
Blood Lipid Profile ◽  
Outpatient Group ◽  
Significant Difference ◽  
Patient Groups ◽  
The Mean

Abstract Background Dyslipidemia has been reported in patients with virus infections. This study was performed to evaluate the blood lipid profile in the patients with coronavirus disease 2019 (COVID-19), and exploring the underlying factors in its development and their predictive value for the severity of COVID-19.Methods In a case-control study, the lipid profile of patients with COVID-19 at the first admitted to two clinical centers in the west of Iran (July 2020 to Dec. 2020) and age- and gender-matched healthy people were explored. Three groups of controls, patients with the severe form of Covid-19 (admitted to the intensive care unit (ICU)), patients with Covid-19 with less intensity (outpatient admission), were defined for the subjects included in the study. The predictive values of different variables obtained from medical records for COVID-19 severity were analyzed.Results Generally, 48 outpatients and 49 ICU patients, including 70 men and 23 women with a mean age of 62.4±13.5 years, were included in the study. The control group consisted of 32 people, match sex and age with the patient groups. The mean triglyceride (TG) in the Covid-19 groups was higher than the control group, but there was no significant difference between them. The mean cholesterol in the patient groups was lower than the control group (p=0.001). The mean of low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol (HDL-C) was significantly different in the patient groups; HDL-C in the ICU group was more than outpatient, and LDL-C in the outpatient group was more than ICU (P<0.05). LDL-C and HDL-C in the ICU group were less than the control group, but there was no statistically significant difference between the two mentioned groups. The frequency of diabetes and hypertension was higher in the ICU group than in the outpatient group (P<0.001). Furthermore, LDL-C level was associated with disease severity (odds ratio (OR): 0.966, 95% confidence interval (CI): 0.944-0.989, P= 0.004).Conclusion Lipid profiles in Covid-19 patients have different faces from healthy individuals. In the severe form, the lipid status has a different profile from the less severe form of Covid-19 disease. LDL-C level can be used as an indicator to determine the severity of Covid-19 disease.

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