scholarly journals Shorter Length of Gonadotropin Stimulation is Associated with Adverse IV F outcomes: A Retrospective Analysis

2018 ◽  
Vol 2 (1) ◽  
Keyword(s):  
Ovarian Reserve ◽  
Chi Square ◽  
Cycle Number ◽  
Oocyte Yield ◽  
Gonadotropin Stimulation ◽  
Secondary Outcomes ◽  
Student’S T ◽  
The Impact ◽  
Student’S T Test ◽  
Hcg Trigger

Background: The impact of the length of gonadotropin stimulation (LOS) on IVF outcome has been studied by several groups. Results so far have been conflicting. The primary aim was to evaluate the impact of LOS on pregnancy rates and oocyte yield. Secondary outcomes included comparison of outcome based on LOS separately in gonadotropinreleasing hormone (GnRH) agonist (GnRH-a) and antagonist (GnRH-ant) cycles. Methods: Retrospective review of IVF cycles managed by a single provider in a private clinic. Data was collected for demographic, stimulation, embryology and clinical outcome parameters. Oocyte yield (the ability to obtain an oocyte from a proper sized follicle) was calculated for each cycle (number of oocytes retrieved/ follicles >14 mm at last scan). LOS was divided into short (≤8 days), normal (9-12 days), and prolonged (≥13 days). Student’s t-test, ANOVA, and Chi-Square tests were used. Results: Outcome based on 295 IVF cycles (GnRH-a: 94 and GnRH-ant: 201) were analyzed. Overall pregnancy rate (PR) was 36.3%. Age, ovarian reserve, number of available and transferred embryos didn’t differ in the three groups. Shorter cycles compared unfavorably to normal and prolonged stimulations regarding oocyte yield (1.2 vs 1.5 vs 1.9, P<0.05) and PR (17.6% vs 40.9% vs 28.7%, P<0.05). Oocyte yield was significantly lower in cycles ≤8 days in both the GnRH-a and GnRH-ant groups when compared to longer stimulation. Conclusions: Quicker response to gonadotropin stimulation may suggest diminished ovarian reserve but could indicate inadequate time for oocyte/ endometrial maturation to occur. LOS should be considered prior to hCG trigger administration.

scholarly journals Clinical and biological profiles of older adults aged 50 and over compared to those under 50 in people living with HIV attending Kinshasa University Teaching Hospital (DR Congo)

2021 ◽  
Vol 5 (2) ◽  
pp. 087-095
Author(s):  
Mbula MMK ◽  
Longo-Mbenza B ◽  
Situakibanza HNT ◽  
Mananga GL ◽  
Makulo JRR ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Teaching Hospital ◽  
University Teaching ◽  
People Living With Hiv ◽  
Chi Square ◽  
Stage 4 ◽  
History Of ◽  
Student’S T ◽  
Living With Hiv ◽  
Student’S T Test

Background: The survival of people living with HIV (PLWHIVs) is increased and Health systems will have to deal with the early-aging-associated medical conditions. Objective: The objective of this study is to compare the clinical and biological profiles of PLWHIVs aged 50 and over and those aged less than 50 years. Material and methods: This study conducted at Kinshasa University Teaching Hospital (KUTH) covers 6 years. The clinical and biological characteristics of PLWHIVs aged 50 and over were compared with those under 50. Statistical analysis used the means ± SD, the calculation of frequencies, Student’s t-test and Chi-square. Results: PLWHIVs aged 50 or over represented 35.1%. Their average age was 58.0 ± 4.8 years. Women predominate among those under 50 and men among those 50 and over. Married people were more numerous (54% among those under 50). There were more unemployed (50% of PLHIV under 50). Patients 50 years and older were significantly classified as WHO stage 4 with a high frequency of history of tuberculosis, genital herpes, high blood pressure, smoking, vomiting, hepatomegaly, moderate elevation of diastolic blood pressure (DBP) and sytolic blood pressure (SBP), tuberculosis and anemia. Those under 50 had a significantly increased frequency of shingles, hepatitis B-hepatitis C, headaches and more survivals. The mean of Hb, HDL-C, and CD4s+ were significantly lower in patients 50 years and older, and urea, LDL-C, and ALAT levels were significantly higher. Conclusion: The average age was higher from 50 years old. These PLWHIVs were more frequently in WHO stage 4 with more common TB and anemia. Their Hb, HDL-C, and CD4s+ levels were lower while their urea, LDL-C and ALAT levels were significantly elevated.

scholarly journals Effect of ondansetron on spinal induced hypotension in caesarean deliveries

2020 ◽  
Vol 8 (4) ◽  
pp. 193-199
Author(s):  
Pujan Balla ◽  
Anil Shrestha ◽  
Ninadini Shrestha ◽  
Navindra Bista ◽  
Moda Nath Marhatta
Keyword(s):  
Spinal Anesthesia ◽  
Elective Caesarean Section ◽  
P Value ◽  
Chi Square ◽  
Induced Hypotension ◽  
Intergroup Comparison ◽  
Chi Square Test ◽  
The Mean ◽  
Student’S T ◽  
Student’S T Test

Background: Spinal anesthesia is the preferred technique of anesthesia employed for caesarean sections. However, it is very often complicated by hypotension. Different drugs and techniques have been used to prevent the hypotension induced by spinal anesthesia. In this study, the effect of ondansetron on the prevention of hypotension after spinal anesthesia was evaluated. Objectives: To determine the effect of prophylactic ondansetron on prevention of spinal induced hypotension in elective caesarean section. Methodology: Eighty-six parturients planned for elective caesarean deliveries were randomized into two groups of 43 each. Group O received Ondansetron 4 mg (4 ml) and Group S received Normal Saline (4 ml) intravenously 10 minutes prior to spinal anesthesia. Blood pressure, heart rate, phenylephrine requirements, occurrence of nausea and vomiting and APGAR scores of neonates were compared between the groups. Hemodynamic data was analyzed using Student’s t-test for intergroup comparison and ANOVA was used for intragroup comparison. Categorical data was analyzed using Pearson Chi-Square test. For all determinants, p-value <0.05 was considered significant. Results: Occurrence of hypotension in Group O (20.9 %) was significantly lower than in Group S (72.1%) (p < 0.05). The mean arterial pressure was significantly higher in Group O at 2, 6, 8, 12 and 14 minutes (p < 0.05). The use of phenylephrine (37.21 mcg vs. 146.51 mcg, p < 0.05) and occurrence of nausea (11.6%, vs. 41.9% p < 0.002) was significantly lower in ondansetron group. Conclusion: Ondansetron is effective in preventing spinal induced hypotension in elective caesarean sections.

scholarly journals Fishery regulamentation or ethnoknowledge? The dilemma of the management of the mapará fisheries on the lower Tocantins river in northern Brazil

2021 ◽  
Vol 10 (11) ◽  
pp. e131101118963
Author(s):  
Esther Mirian Cardoso ◽  
Paulo Allison Costa da Mata ◽  
Matheus dos Santos Souza ◽  
Maria Clara Pinheiro de Souza ◽  
Victoria Isaac
Keyword(s):  
Socioeconomic Development ◽  
Economic Importance ◽  
Chi Square ◽  
Great Economic Importance ◽  
Chi Square Test ◽  
Northern Brazil ◽  
The Mean ◽  
Tocantins River ◽  
Student’S T ◽  
Student’S T Test

The fishery of mapará (Hypophthalmus marginatus) is of great economic importance in the Amazon region. Despite this, it is observed that the current norms of management disagree with the ethnoknowledge of fishermen of the Tocantins river. Therefore, there are many seizures and fines in the Tocantins Low region. This work appeared as a demand of the fishermen of the region and had as purpose to test the pertinence of the fishing legislation on the capture of the species and to provide subsidies for the adaptation of the norms to the local reality. For this, a mapará fishery was taken on the Pindobal Grande river, in the municipality of Igarapé-Miri, in the state of Pará. A sample of the captured individuals was collected, and identification, sexing and biometry were done. Fishing was described, and the sex ratio tested with the Chi-Square test and the mean length differences between the sexes with the Student's t-test. The results were compared with current legislation and literature data. The captured mapará individuals were mostly above 30 cm, as determined by legislation. It is concluded that, despite using a network that is prohibited, the capture of the species in the region acts selectively, due to the ethno-cognition and the fisherman's action ("taleiro"). Therefore, it is necessary that the legislation be revised, seeking the reconciliation between the conservation of ecosystems, the traditional knowledge and the socioeconomic development of the region.

scholarly journals Sports potential modeling of young basketball players: a preliminary analysis

2019 ◽  
Vol 21 ◽  
Author(s):  
Dilson Borges Ribeiro Junior ◽  
Jeferson Macedo Vianna ◽  
André de Assis Lauria ◽  
Emerson Filipino Coelho ◽  
Francisco Zacaron Werneck
Keyword(s):  
Adult Height ◽  
High Potential ◽  
Basketball Players ◽  
Chi Square ◽  
Chi Square Test ◽  
Student’S T ◽  
The Relationship ◽  
Student’S T Test ◽  
Adult Stature

Abstract The aims of this study were: 1) to evaluate the sports potential of young basketball players; 2) to identify variables that discriminate sports potential assessed by coaches; 3) to verifythe relationship between classification of the multidimensional profile of athletes and classification of the sports potential by coaches. Sixty-two young basketball players aged 15.6±1.1 years from U-15 (n = 24) and U-17 (n = 38) categories participated in the study. A test battery was applied to evaluate sports potential indicators: 1) anthropometric; 2) physicomotor; 3) psychological;4) skills;5) socio-environmental;6) maturational and 7) sports potential.Clusteranalysis was performed in three groups: high, medium and low potential. Student’s t-test was used for the comparison between athletes evaluated by the coach as excellent and the others and the Chi-Square test to verify the relationship between sports potential classifications. It was observed that in the high-potential group, athletes were chronologically older, with higher % predicted adult height (PMS), competitive and determined sports orientation, higher body size, lower skinfold summation, and greater physicomotor performance. In comparison with other athletes, high-potential basketball players presented higher stature, wider wingspan,longer limb length, greater predicted adult stature and higher Z score of the % PMS. It could be concluded that the multidimensional approach was useful for the evaluation of the sports potential of young basketball players, requiring the use of multidimensional variables, in addition to coaches’ opinion regarding the potential of their athletes.

scholarly journals Analgesic prescribing habits and patterns of Canadian chief urology residents: A national survey

2020 ◽  
Vol 14 (6) ◽  
Author(s):  
Ali Dergham ◽  
Greg Hosier ◽  
Melanie Jaeger ◽  
J. Curtis Nickel ◽  
D. Robert Siemens ◽  
...  
Keyword(s):  
Pain Management ◽  
Response Rate ◽  
Formal Training ◽  
Knowledge Gaps ◽  
Opioid Prescribing ◽  
Review Course ◽  
Student’S T ◽  
The Impact ◽  
Student’S T Test

Introduction: Prior studies have identified significant knowledge gaps in acute and chronic pain management among graduating urology residents as of five years ago. Since then, there has been increasing awareness of the impact of excessive opioid prescribing on long-term narcotic use and development of adverse narcotic-related events. However, it is unclear whether the attitudes and experience of graduating urology residents have changed. We set out to evaluate the attitudes and experience of graduating urology residents in prescribing opioid/non-opioid analgesia for acute (AP), chronic non-cancer (CnC), and chronic cancer (CC) pain. Methods: Graduating urology residents were surveyed at a review course in 2018. The survey consisted of open-ended and close-ended five-point Likert scale questions. Descriptive statistics, Mann-Whitney U-test, and Student’s t-test were performed. Results: A total of 32 PGY5 urology residents completed our survey (92% response rate). The vast majority agreed that formal training in managing AP/CnC/CC to be valuable (91/78/81%). Most find their training in CnC/CC management to be inadequate and are unaware of any opioid prescribing guidelines; 66% never counsel patients on how to dispose of excess opioids. In general, 88% are comfortable prescribing opioids, whereas most are very uncomfortable prescribing cannabis or antidepressants (100%/78%). Residents reported the Acute Pain Service as the highest-rated resource for information, and dedicated textbooks the least. Conclusions: This survey demonstrated that experience in pain management remains variable among urology residents. Knowledge gaps remain, particularly in the management of chronic cancer/non-cancer pain.

scholarly journals ‘Blood in pee’ campaign: Increased demand on secondary care with no change in cancers diagnosed

2018 ◽  
Vol 12 (1) ◽  
pp. 15-19
Author(s):  
Kunjan Patel ◽  
Susan Jane Hall ◽  
Kamath Shraddha ◽  
Richard Stanford ◽  
Simon Williams ◽  
...  
Keyword(s):  
Cancer Awareness ◽  
Level Of Evidence ◽  
Awareness Campaigns ◽  
Economic Background ◽  
Kolmogorov Smirnov ◽  
The Mean ◽  
Student’S T ◽  
The Impact ◽  
Index Of Multiple Deprivation ◽  
Student’S T Test

Objective: As part of the national Be Clear on Cancer campaign, the ‘blood in pee’ campaign was launched in 2013. We aimed to evaluate the impact of the campaign on 2-week wait (2WW) referrals and the resulting diagnoses of malignancy at a single trust, and secondly, to evaluate the socio-economic background of patients referred. Patients and methods: Suspected cancer 2WW patients in the 3 months pre- and post-campaign were included. Demographics, investigations and diagnoses were recorded. A Kolmogorov–Smirnov test demonstrated a normal distribution. The data were treated as parametric and analysed with the unpaired Student’s t-test. Results: Referrals for visible haematuria significantly increased by 52% from 135 pre-campaign to 205 post-campaign ( p = 0.03). There was a fall in the proportion of patients diagnosed with malignancy from 20.27% pre-campaign to 15.36% post-campaign. The mean index of multiple deprivation score of referrals did not change: p = 0.43. Conclusion: This campaign has increased referrals without increasing the proportion of malignancies diagnosed, placing large demand on services without benefit or extra funding. Nor has the campaign effectively reached deprived socio-economic groups. There is little evidence as to the efficacy of untargeted cancer awareness campaigns and further work is needed to improve their pick-up of malignancies. Level of evidence: 2C

Lymphoscintigraphic findings: delayed oedema after great saphenous vein harvesting

2011 ◽  
Vol 26 (5) ◽  
pp. 185-190 ◽  
Author(s):  
C E Q Belczak ◽  
J M P de Godoy ◽  
A F Cruz ◽  
A L Tyszca ◽  
H J G Neto ◽  
...  
Keyword(s):  
Saphenous Vein ◽  
Coronary Bypass ◽  
Cross Sectional Study ◽  
Lower Limbs ◽  
Water Displacement ◽  
Chi Square ◽  
Cross Sectional ◽  
Student’S T ◽  
Alpha Error ◽  
Student’S T Test

Objective The aim of this study was to identify lymphoscintigraphic changes associated with lower-extremity oedema after the harvesting of the saphenous vein using a series of short Q2 incisions for coronary bypass. Method Forty-four patients (32 males and 12 females) with a mean age of 62.7 ± 7.8 (47–75 years old) were evaluated in a retrospective, quantitative, cross-sectional study from June 2007 to January 2008, three to 188 months (mean: 46 months) after the surgical procedure. Assessment was by water displacement volumetry and lymphoscintigraphy of the lower limbs. Results expressed as means with standard deviations were compared employing the Student's t-test and the chi-square or Fisher's exact tests were used to compare data expressed as frequencies. An alpha error of 5% was considered acceptable ( P ≤ 0.05). Results The presence of dermal backflow, as identified by lymphoscintigraphy with an accumulation of radiotracer in the thoracic duct and popliteal lymph nodes was significantly greater on the operated side. Conclusion There was a significant association between dermal backflow and delayed oedema.

Risk factors for biopsy complications in initial versus subsequent biopsies in native and transplant kidneys

2020 ◽  
pp. 028418512096668
Author(s):  
Björn Peters ◽  
Henri Afghahi ◽  
Salar Maitlo ◽  
Henrik Hadimeri
Keyword(s):  
Risk Factors ◽  
Binary Logistic Regression ◽  
Chi Square ◽  
Exact Test ◽  
Major Complications ◽  
Native Kidney ◽  
Transplant Kidney ◽  
Student’S T ◽  
Biopsy Complications ◽  
Student’S T Test

Background Few studies exist about risk factors for complications in subsequent biopsies. Purpose To explore risk factors for complications in initial versus subsequent biopsies in native and transplant kidneys, which may predict biopsy complications. Material and Methods In a multicenter study, 2830 native kidney biopsies (4.3% subsequent) were analyzed for major complications (1251 of these were also analyzed for minor) and 667 transplant kidney biopsies (29% subsequent) were analyzed for major and minor complications. No death or nephrectomy were described. Fisher’s exact test, Student’s t-test, chi-square analyses, and univariate and multiple binary logistic regression analyses were employed; P < 0.05 was considered significant. Results In initial native kidney biopsies, the frequency of major complications was higher in women compared to men (odds ratio 1.6, 95% confidence interval 1.1–2.2), in younger patients (50 vs. 54 years, P = 0.007), and in patients with lower weight (78 vs. 82 kg, P = 0.005). In subsequent native kidney biopsies, patients with major complications had a higher systolic blood pressure (145 vs. 132 mmHg, P = 0.03). In initial transplant kidney biopsies, biopsies with major complications had less glomeruli in the biopsy (17 vs. 24, P = 0.046). In subsequent transplant kidney biopsies, patients with major complications had a higher mean arterial pressure (112 vs. 98 mmHg, P = 0.002). In subsequent native kidney biopsies, there was a higher number of SLE-nephritis (12% vs. 4.6%, P = 0.001) compared to initial biopsies. Conclusion The different types of risk factors for complications in initial versus subsequent renal biopsies could be important for the clinicians to improve patients’ safety.

Effectiveness of Interactive Videodisc Instruction for the Continuing Education of Paramedics

1994 ◽  
Vol 9 (3) ◽  
pp. 165-171 ◽  
Author(s):  
Michael Heller ◽  
Walt A. Stoy ◽  
Larry J. Shuman ◽  
Harvey Wolfe ◽  
Chalice A. Zavada
Keyword(s):  
Computer Analysis ◽  
Life Support ◽  
Advanced Life Support ◽  
Interactive Videodisc ◽  
Chi Square ◽  
Group Score ◽  
Subject Areas ◽  
Student’S T ◽  
Mean Compliance ◽  
Student’S T Test

AbstractObjectives:To evaluate the effectiveness of interactive videodisc (IVD) instruction of paramedics through the use of computer analysis of trip sheets.Design/Setting:Prospective, controlled, in an urban 9-1-1, paramedic, emergency medical services (EMS) system with total call volume of 62,000/year; 15,000 advanced life support (ALS).Interventions:All 150 paramedics in the system received eight hours of IVD instruction covering five subject areas: 1) airway; 2) head/cervical trauma; 3) chest; 4) shock; and 5) cardiac arrest. Trip sheets from 9,943 runs in the pre-IVD period were subjected to computer analysis, and a compliance score was generated using previously developed algorithms that assigned a weight to each omission and commission. After a nine-month IVD training period, 4,303 cases were collected and analyzed in the post-IVD period. Statistical analyses were made using “Student's“ t-test and Chi-square with alpha set at 0.05.Exclusions:Only those records of adult patients who fit one of the five protocols were eligible for computer analysis. Of the 9,943 cases in the pre-IVD group, 480 (4.8%) were excluded, all due to inadequate data recording by the paramedics. A statistically similar portion, 233 (5.4%) of the 4,303 post-IVD instruction cases were excluded (p = .15).Results:Overall the mean compliance score of the pre-IVD group was 0.65 ±0.19 (±SD). The post-IVD group score was 0.65 ±0.19 (p = 0.99). Analysis of scores for each algorithm also showed no significant differences. This study had an observed power of .94 to detect a difference in compliance as small as 0.030.Conclusion:Eight hours of IVD instruction did not result in improved paramedic performance as judged by computer analysis of trip sheets.

Mandibular Condyle Lesions in Children with Juvenile Idiopathic Arthritis

2008 ◽  
Vol 45 (1) ◽  
pp. 57-62 ◽  
Author(s):  
Sossani Sidiropoulou-Chatzigianni ◽  
Moschos A. Papadopoulos ◽  
George Kolokithas
Keyword(s):  
Juvenile Idiopathic Arthritis ◽  
Statistical Evaluation ◽  
Mandibular Condyle ◽  
Chi Square ◽  
Temporomandibular Joints ◽  
Student’S T ◽  
The Right ◽  
Bilateral Lesions ◽  
Bilateral Destruction ◽  
Student’S T Test

Objective: To assess the prevalence of radiographically detectable destruction of the temporomandibular joints in children with juvenile idiopathic arthritis and to study the possible relationships between condylar destruction and type and duration of the disease, as well as the type of occlusion. Material And Method: The study group consisted of 66 children with juvenile idiopathic arthritis (27 boys, 39 girls; mean age, 11.9 years). The possible presence of condylar destruction was examined in panoramic radiographs. The medical history and the type of malocclusion were registered also. The statistical evaluation was performed by means of descriptive statistics, Student's t test, Pearson's chi-square, and an analysis of variance test. The whole procedure was repeated after a 4-week interval to estimate the error of the method. Results: Of the children with juvenile idiopathic arthritis, 50% showed some form of condylar destruction. Significant correlation was found between the type of the disease and the condyles affected. In the polyarticular type of juvenile idiopathic arthritis, 75% of the children presented affected condyles and 55.6% of them showed lesions bilaterally. The condylar affection was found to be independent of sex, although girls showed a tendency to bilateral lesions. In children with unilateral destruction, the right condyle was affected four times more frequently than the left. The duration of juvenile idiopathic arthritis seems to be significantly correlated to condylar destruction and especially to bilateral destruction. Conclusion: Children with juvenile idiopathic arthritis presented a remarkable prevalence of condylar destruction, which was correlated to the type and duration of the disease.

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