scholarly journals Variations in Essential Elements After Malignant Transformation of Kidney Epithelial Tubular Cells

2020 ◽  
Vol 5 (6) ◽  
Keyword(s):  
Metabolic Pathways ◽  
Inductively Coupled Plasma ◽  
Element Concentration ◽  
Target Therapy ◽  
Essential Elements ◽  
New Drugs ◽  
Tubular Cells ◽  
Inductively Coupled ◽  
Icp Ms ◽  
Plasma Mass Spectrometry

Cell line-based research is a valuable tool for the study of cancer physiopathology and the discovery of new drugs for use in clinical practice. In this study, inductively coupled plasma mass spectrometry (ICP-MS) was used to estimate Ca, Co, Cu, Fe, K, Mg, Mn, Na, P, S, Se, and Zn in epithelial tubular cells (HK-2) and kidney tumor cells (Caki-1 cells). The most relevant difference was a decrease in the contents of Ca, Cu, Fe, K, Mg, Mn, Na, P, S, and Zn. A significant accumulation of Co was also detected in Caki-1 cells. The fold change variation of each element concentration between HK-2 and Caki-1 cells was Ca (‒0.40), Co (1.37), Cu (‒0.68), Fe (‒0.56), K (‒0.40), Mg (‒0.41), Mn (-0.54), Na (‒0.33), P (‒0.31), S (‒0.26), and Zn (‒0.73). These findings indicate that the elements mainly affect the metabolic pathways of epithelial kidney cells. Thus, our findings open a new avenue for RCC target therapy.

scholarly journals Evaluation of Selected Essential Elements in Khalas Dates from Date Palm Determined by Inductively Coupled Plasma-Mass Spectrometry

2019 ◽  
Vol 2019 ◽  
pp. 1-5
Author(s):  
Eid I. Brima
Keyword(s):  
Mass Spectrometry ◽  
Saudi Arabia ◽  
Inductively Coupled Plasma ◽  
Daily Intake ◽  
Essential Elements ◽  
Limited Information ◽  
Inductively Coupled ◽  
Icp Ms ◽  
Plasma Mass Spectrometry ◽  
Wet Weight

In terms of nutrition, dates are an important commodity because they are a source of carbohydrates and minerals. Saudi Arabia is the second largest producer of dates worldwide. Khalas is the tenth most popular date type in the Kingdom of Saudi Arabia (KSA), but only limited information related to the levels of essential nutrients in Khalas dates is available. The concentrations of Mn, Cu, Zn, and Se were determined using inductively coupled plasma-mass spectrometry (ICP-MS). The average concentrations in wet weight were as follows (mg/kg): Mn (2.90 ± 0.54), Cu (1.78 ± 0.64), Zn (1.72 ± 0.42), and Se (0.10 ± 0.06). The calculated intakes (μg/kg bw day) per 100 g dates for each element were as follows: Mn (4.14), Cu (2.54), Zn (2.46), and Se (0.14), which represent 0.14%, 0.51%, 0.25%, and 0.2%, respectively, of the provisional maximum tolerable daily intake (PMTDI) recommended by the EFSA/WHO. It was found that levels of the analysed essential elements in up to 100 g of Khalas dates do not exceed the level set by the EFSA/WHO.

scholarly journals Canned sea fish marketed in Serbia: their zinc, copper, and iron levels and contribution to the dietary intake

2018 ◽  
Vol 69 (1) ◽  
pp. 55-60
Author(s):  
Aleksandar R. Popović ◽  
Dubravka J. Relić ◽  
Danijela V. Vranić ◽  
Jelena A. Babić-Milijašević ◽  
Lato L. Pezo ◽  
...  
Keyword(s):  
Inductively Coupled Plasma ◽  
Daily Intake ◽  
Essential Elements ◽  
Acid Digestion ◽  
Tomato Sauce ◽  
Inductively Coupled ◽  
Canned Tuna ◽  
Icp Ms ◽  
Plasma Mass Spectrometry ◽  
Sea Fish

Abstract The aim of this study was to determine the levels of Zn, Cu, and Fe in three canned fish species marketed Serbia to see if they meet recommended daily intake requirements or exceed safety limits. We collected a total of 207 samples of canned tuna, sardine, and mackerel, in oil or tomato sauce and analysed them with inductively coupled plasma mass spectrometry (ICP-MS) after acid digestion. The highest levels were obtained for Zn (15.1 mg kg-1) and Cu (1.37 mg kg-1) in sardine in oil and tomato sauce, respectively, and for Fe (18.98 mg kg-1) in mackerel in tomato sauce. Our results keep within the ranges reported by several national food databases and available literature data, with a few exceptions. Our findings also single out canned sardines as the richest source of the three essential elements combined. The estimated daily intake (EDI) of the three essential elements, however, was subpar, and ranged between 0.14 % and 0.72 % of the recommended dietary allowance (RDA) for Zn, Cu, and Fe.

Elemental chemical composition and As speciation in rice varieties selected for biofortification

2020 ◽  
Vol 12 (16) ◽  
pp. 2102-2113 ◽  
Author(s):  
Bruna Moreira Freire ◽  
Vivian da Silva Santos ◽  
Pericles de Carvalho Ferreira Neves ◽  
Juliana Maria Oliveira Souza Reis ◽  
Samuel Simião de Souza ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Inductively Coupled Plasma ◽  
Toxic Elements ◽  
Hydride Generation ◽  
Essential Elements ◽  
Rice Varieties ◽  
Inductively Coupled ◽  
Icp Ms ◽  
Plasma Mass Spectrometry ◽  
Rice Samples

Toxic elements, essential elements and other elements were determined in Brazilian rice by inductively coupled plasma-mass spectrometry (ICP-MS). A method for As speciation using hydride generation was developed and applied in rice samples.

Concentrations of toxic and essential elements in Lebanese bread

2012 ◽  
Vol 84 (2) ◽  
pp. 181-190 ◽  
Author(s):  
Rola Bou Khouzam ◽  
Pawel Pohl ◽  
Baydaa Al Ayoubi ◽  
Farouk Jaber ◽  
Ryszard Lobinski
Keyword(s):  
Inductively Coupled Plasma ◽  
Essential Elements ◽  
Inductively Coupled ◽  
Icp Ms ◽  
Geographical Regions ◽  
Plasma Mass Spectrometry ◽  
Dry Seasons ◽  
Double Focusing ◽  
Ultratrace Elements ◽  
Wet And Dry Seasons

Concentrations of 20 minor, trace, and ultratrace elements relevant to human health (Ag, Al, As, Cd, Co, Cr, Cu, Fe, Hg, Li, Mn, Mo, Ni, Pb, Sb, Se, Si, Sn, V, and Zn) were determined in three varieties of Lebanese bread (white and brown double loaf bread, Saj bread) sampled at five geographical regions (Grand Beirut, South of Lebanon, North of Lebanon, Mount of Lebanon, and Beka’a) during the wet and dry seasons. The analyses were carried out by double-focusing sector-field inductively coupled plasma-mass spectrometry (DF-SF-ICP-MS). The data were discussed in terms of nutritional elements supplied by type of bread, the risk of contamination by toxic elements (As, Cd, Pb) owing to the manufacturing process, and variations related to geographic distribution and seasonal sampling.

scholarly journals Discrimination of Tunisian Honey by Mineral and Trace Element Chemometrics Profiling

Foods ◽  
2021 ◽  
Vol 10 (4) ◽  
pp. 724
Author(s):  
Giuseppa Di Bella ◽  
Angela Giorgia Potortì ◽  
Asma Beltifa ◽  
Hedi Ben Mansour ◽  
Vincenzo Nava ◽  
...  
Keyword(s):  
Health Risks ◽  
Inductively Coupled Plasma ◽  
Chemical Elements ◽  
Essential Elements ◽  
Potential Health ◽  
Inductively Coupled ◽  
Sidi Bouzid ◽  
Icp Ms ◽  
Plasma Mass Spectrometry ◽  
Prickly Pears

The concentrations of 19 chemical elements have been determined in 36 honey samples of different botanical (wildflower, eucalyptus, eucalyptus red flowers, prickly pears, lemon blossom, thyme, almond, rosemary and jujube) honeys from the three geographical areas of Tunisia (Sidi Bouzid, Nabeul and Sfax) using inductively coupled plasma mass spectrometry (ICP-MS). The aim of this work was to use the multielement analysis together with chemometric tools to verify the botanical and the geographical origin of honeys. The correlation on the basis of mineral element content between the honey samples and their botanical and/or geographical origins was in some measure achieved. The data collected on the samples were also used to evaluate the nutritional quality and the potential health risks associated with elements via consumption of the Tunisian honey. According to the results obtained, the intake of essential elements was small, and the potential health risks associated with toxic or potentially toxic elements via consumption of this food were overall insignificant.

scholarly journals Determination of Essential Elements in Indian Rice Samples Before and After Washing by ICP-MS

2020 ◽  
Vol 32 (12) ◽  
pp. 2971-2976
Author(s):  
Amal M. Al-Mohaimeed ◽  
H.F.A. Al-Harbi
Keyword(s):  
Inductively Coupled Plasma ◽  
Essential Elements ◽  
Analytical Technique ◽  
Inductively Coupled ◽  
Icp Ms ◽  
Relative Standard ◽  
Before And After ◽  
Zn And Cu In ◽  
Plasma Mass Spectrometry ◽  
Rice Samples

In this study, a simple analytical technique was established to determine the content of essential elements (K, P, Mg, Ca, Zn, and Cu) in four samples of Indian rice. The influence of soaking, washing, and cooking on the essential elements concentration was determined. Twenty samples employed in this study, were contained in closed vessels and subjected to microwave-assisted digestion. Six elements (K, P, Ca, Mg, Zn, and Cu) were analyzed and determined through inductively coupled plasma mass spectrometry (ICP-MS). In the analyzed elements, the concentration of potassium elements and phosphate was the highest and that of zinc and copper was the lowest. The low values of the limits of detection (LOD) and limits of quantification (LOQ) with a relative standard deviation (%RSD) of 0.2-3% were observed.

scholarly journals Preliminary Study on Characterization of Edible Oils Using Inductively Coupled Plasma Mass Spectrometry (ICP-MS) and Isotope Ratio Mass Spectrometry (IRMS)

2020 ◽  
Vol 71 (5) ◽  
pp. 283-289
Author(s):  
Cezara Voica ◽  
Andreea Maria Iordache ◽  
Marius Gheorghe Miricioiu ◽  
Dana Alina Magdas ◽  
Gabriela Cristea
Keyword(s):  
Mass Spectrometry ◽  
Inductively Coupled Plasma ◽  
Isotope Ratio ◽  
Edible Oils ◽  
Microwave Digestion ◽  
Isotope Ratio Mass Spectrometry ◽  
Essential Elements ◽  
Inductively Coupled ◽  
Icp Ms ◽  
Plasma Mass Spectrometry

In recent years, increasing attention has been paid to oils consumed by humans. The human body uses oils in the diet for three purposes: energy source, structural component and powerful biological regulators. Elemental profiling of macro-, essential elements constitutes an important tool for quality control in terms of nutritional values of these products. Regarding this, Inductively Coupled Plasma-Mass Spectrometry (ICP-MS) determinations were performed to assess the quantitative complement of essential mineral and toxic metals content of different edible oil types, from Romania market, summing 33 samples, after microwave digestion. Additionally, the carbon stable isotope ratios (13C) were determined by Isotope Ratio Mass Spectrometry (IRMS) in order to differentiate the specific fingerprint of investigated oils.

scholarly journals Essential and Non-essential Trace Elements in Milks and Plant-Based Drinks

2021 ◽  
Author(s):  
Montse Marquès ◽  
Eudald Correig ◽  
Esther Capdevila ◽  
Eva Gargallo ◽  
Neus González ◽  
...  
Keyword(s):  
Inductively Coupled Plasma ◽  
Toxic Elements ◽  
Dietary Habits ◽  
Production Systems ◽  
Goat Milk ◽  
Essential Elements ◽  
Inductively Coupled ◽  
Three Samples ◽  
Icp Ms ◽  
Plasma Mass Spectrometry

AbstractAlthough milk and plant-based drinks are widely consumed foodstuffs with high nutritional value, their consumption may also mean intake of non-essential/toxic elements becoming a risk for human health. This study was aimed at determining the concentrations of essential (Ca, Co, K, Mg, Mn, Na, Ni and P) and non-essential/toxic (Hg, Pb, U and V) elements in milks (cow and goat), plant-based drinks (soy, almond, rice and oat) and infant formulas from organic and conventional production systems. Lactose-free, fresh and ultra-high-temperature (UHT) milks were also included. Chemical analyses were performed by means of inductively coupled plasma-mass spectrometry (ICP-MS). The content of the elements hereby assessed did not depend on the production system and the presence of lactose. However, significant differences were found in the concentrations of multiple elements when comparing sterilization methods, source (animal vs. plant-based) and animal species. Non-essential elements were not detected in milks and plant-based drinks, excepting Pb, which was detected in three samples. While the consumption of goat milk is recommended, considering the global intake of essential elements and the absence of non-essential elements, further studies should be conducted to confirm the absence of non-target toxic elements at very low trace levels. On the other hand, the best plant-based drinks are those made up with almonds (intake of Ca) and soy (K and Mg). The current results should be useful to help the population to balance the benefits and risks from milks and plant-based drinks consumption, as well as to adapt their dietary habits.

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