scholarly journals Serum Theophylline Concentrations in very Preterm Neonates Receiving Intravenous Aminophylline for Apnea

2021 ◽  
Vol 73 (8) ◽  
pp. 526-531
Author(s):  
Pimol Wongsiridej ◽  
Sopapan Ngerncham ◽  
Siripa Usaha ◽  
Weerawadee Chandranipapongse ◽  
Tim R. Cressey ◽  
...  
Keyword(s):  
Maintenance Dose ◽  
Univariate Analysis ◽  
Cross Sectional Study ◽  
Preterm Neonates ◽  
Therapeutic Drug ◽  
Baseline Heart Rate ◽  
Loading Dose ◽  
Cross Sectional ◽  
Serum Theophylline ◽  
Theophylline Level

Objective: To determine the percentage of neonates who achieved therapeutic theophylline level (TTL) after receiving standard IV loading/maintenance aminophylline doses. To assess factors associated with achieving therapeutic theophylline concentrations and to describe adverse effects of aminophylline.Materials and Methods: This was a pilot, cross-sectional study. Preterm neonates ≤34 weeks’ gestation for which aminophylline was indicated for treatment of apnea were enrolled. Standard IV aminophylline dosage is 8 mg/kg loading dose, followed by 1.5 mg/kg maintenance dose every 8 hours. Serum theophylline concentrations were measured prior to the 8th maintenance dose. Descriptive statistics, univariate and multivariate analyses were performed.Results: Twenty-five neonates (52% female) were enrolled: mean (standard deviation) gestational age and birth weight were 30.4 (2) weeks and 1,277 (415) grams, respectively. Aminophylline was initiated at a median (25%tile, 75%tile) postnatal age of 4 (1, 8) days. Baseline heart rate prior to the loading dose was 153 (13) beats-per-minute. Sixty percent of neonates achieved a therapeutic theophylline level. In the univariate analysis, being male and postnatal age ≤5 days were associated with successfully achieving a TTL. After adjusting for gender, postnatal age ≤5 days was the only factor associated with achieving a TTL (adjusted odds ratio 17.7, 95% confidence interval: 1.9, 164.4). Tachycardia and feeding intolerance were observed in 44% and 24% of neonates, respectively.Conclusion: Current IV aminophylline dosing conditions in Thailand achieved TTL in approximately two-thirds of neonates, suggesting therapeutic drug monitoring is beneficial for guiding dosing. A higher maintenance dose could be considered for neonates older than 5 days.

Comparison of Non-radiographic Axial Spondyloarthritis and Ankylosing Spondyltis from a Single Rheumatology Hospital in Morocco

2020 ◽  
Vol 16 (3) ◽  
pp. 240-244 ◽  
Author(s):  
Nessrine Akasbi ◽  
Siar Nihad ◽  
Zoukal Sofia ◽  
El Kohen Khadija ◽  
Harzy Taoufik
Keyword(s):  
Disease Burden ◽  
Axial Spondyloarthritis ◽  
Univariate Analysis ◽  
Cross Sectional Study ◽  
Low Back ◽  
New Classification ◽  
Cross Sectional ◽  
Asas Criteria ◽  
History Of ◽  
High Level

Background: According to the new classification criteria developed by The Assessment of SpondyloArthritis International Society, patients with axial spondyloarthritis (axSpA) can be classified in 2 subgroups: Patients with radiographic axial spondyloarthritis: ankylosing spondylitis patients (AS) and those with non-radiographic axial spondyloarthritis (nr-axSpA). Objective: The aim of the present study is to describe and discuss the differences and similarities between the two subgroups. Patients and Methods: A cross-sectional study was conducted in a single rheumatology hospital in Morocco. These included patients diagnosed as having axial spondyloarthritis according to ASAS criteria 2010, during a period of 6 years. The AS and the nr-axSpA subgroups were compared for the various axSpA-related variables. Results: Of the 277 patients with a diagnosis of axial SpA who were included in this study, 160 had AS and 117 had nr-axSpA. AS and nr-ax-SpA shared a similar age at diagnosis, similar prevalence of low back pain, lumbar stiffness, extra-articular manifestations, BASDAI and BASFI. In the multivariate analysis, AS patients were mainly male with cervical stiffness, enthesitis, coxitis and high level of ESR (erythrocyte sedimentation rate). The females generally had a family history of SpA and arthritis and were associated to the nr-axSpA form in the univariate analysis. Conclusion: This was the first study to characterise patients with AS and nr-axSpA in Morocco. Consistent with other studies published, this study showed that patients with nr-axSpA and patients with AS shared a comparable degree of disease burden.

scholarly journals Healthcare Provider Attitudes toward the Newly Developed COVID-19 Vaccine: Cross-Sectional Study

2021 ◽  
Vol 11 (1) ◽  
pp. 187-194
Author(s):  
Gasmelseed Ahmed ◽  
Zainab Almoosa ◽  
Dalia Mohamed ◽  
Janepple Rapal ◽  
Ofelia Minguez ◽  
...  
Keyword(s):  
Private Hospital ◽  
Univariate Analysis ◽  
Healthcare Providers ◽  
Cross Sectional Study ◽  
Chronic Illnesses ◽  
Sectional Study ◽  
Provider Attitudes ◽  
Cross Sectional ◽  
Electronic Survey ◽  
Consistency Results

Background: During the long wait and the global anxiety for a vaccine against COVID-19, impressively high-safety and effective vaccines were invented by multiple pharmaceutical companies. Aim: We aimed to assess the attitudes of healthcare providers and evaluate their intention to advocate for the vaccine. Methods: This was a cross-sectional study conducted in a tertiary private hospital where an electronic survey was distributed among healthcare providers (HCPs). The survey contained two sections: socio-demographic characteristics and Likert-scale perception, with 72% internal consistency. Results: The response rate to the email survey was 37% (n = 236). In addition, 169 (71.6%) of respondents were women, with more than half (134, 56.8%) aged ≤35 years. A total of 110 (46.6%) had over 10 years of experience, and most of them were nurses (146, 62%). Univariate analysis revealed that older participants significantly accepted and advocated for the new vaccine more than the younger ones. In the multivariate analysis, men were significantly more likely than women to accept and advocate for the new vaccine, as were those with chronic illnesses. Participants with allergy were significantly less likely to accept the vaccine than others. odds ratio (OR) and p-values were 2.5, 0.003; 2.3, 0.04; and 0.4, 0.01, respectively. Conclusion: The acceptance rate for the newly-developed COVID-19 vaccines was average among HCPs. Sex, age, presence of chronic illnesses, and allergy were significant predictors of accepting the vaccine.

scholarly journals HEALTH LITERACY OF INDIVIDUALS UNDERGOING DIALYSIS THERAPY

2019 ◽  
Vol 28 ◽  
Author(s):  
Jéssica Naylla de Melo Bezerra ◽  
Sara Rebeca de Oliveira Lessa ◽  
Marcelo Francisco do Ó ◽  
Givaneide Oliveira de Andrade Luz ◽  
Anna Karla de Oliveira Tito Borba
Keyword(s):  
Health Literacy ◽  
Univariate Analysis ◽  
Cross Sectional Study ◽  
Functional Health ◽  
P Value ◽  
Functional Health Literacy ◽  
Cross Sectional ◽  
Exact Test ◽  
Independent Variables ◽  
Adequate Health Literacy

ABSTRACT Objective: to assess the functional levels of health literacy in individuals undergoing dialysis. Method: a cross-sectional study with 42 patients of the Nephrology Unit of a public hospital in Recife, Brazil, from May to August 2016. Data were collected through scripted interviews and chart analysis. Functional health literacy was measured using the Brazilian version of the Short-Test of Functional Health Literacy in Adults questionnaire. Data analysis was performed using the Statistical Package for Social Sciences (SPSS®) software, version 18.0, with a univariate analysis to verify the association between independent variables and functional health literacy levels using Fisher's exact test. Results: 80.9% of the patients presented inadequate health literacy and 19.1% presented adequate health literacy. The number of correct answers remained between 0-18 in the reading comprehension and in the scheduling appointment card. Among the independent variables, only marital status (p-value=0.018) and personal income (p-value=0.009) were factors associated with the worst scores in the test, indicating that these variables influence the increase in inadequate literacy. Conclusion: the prevalence of inadequate functional literacy was high, reflecting difficulties in understanding and processing health information, which may interfere with therapeutic management and self-care.

scholarly journals Knowledge of healthcare professionals regarding the vertical transmission of syphilis in Fortaleza -CE, Brazil

2014 ◽  
Vol 23 (2) ◽  
pp. 278-285 ◽  
Author(s):  
Denise Maia Alves da Silva ◽  
Maria Alix Leite Araújo ◽  
Raimunda Magalhães da Silva ◽  
Roumayne Fernandes Vieira Andrade ◽  
Heber José de Moura ◽  
...  
Keyword(s):  
Vertical Transmission ◽  
Prevention And Control ◽  
Healthcare Professionals ◽  
Congenital Syphilis ◽  
Venereal Disease ◽  
Univariate Analysis ◽  
Family Health ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
And Control

The aim of this study was to investigate the knowledge of family health strategy professionals regarding the prevention and control of the vertical transmission of syphilis. This cross-sectional study was carried out in Fortaleza, Ceará, Brazil, from August to October 2009. A questionnaire was used, with its correct answers being in line with the recommendations of the Ministry of Health. Univariate analysis was carried out, with frequency distribution, mean and standard deviation. A total of 269 professionals participated, 44.7% had 6 to 10 years of experience in the FHS, and 60% of the questions regarding their knowledge were answered correctly: 75.8% were aware of the request period of the Venereal Disease Research Laboratory (VDRL) test; 78.1% of the alternative drug for the treatment for pregnant women allergic to penicillin, 55.1% of the request period for VDRL for cure and control, and 50.2% of the conduct with a sexual partner. It was concluded that healthcare professionals are unaware of the appropriate actions for the prevention and control of congenital syphilis.

scholarly journals Univariate associations between housing, management, and facility design factors and the prevalence of lameness lesions in fourteen small-scale dairy farms in Northeastern Algeria

2020 ◽  
Vol 13 (3) ◽  
pp. 570-578 ◽  
Author(s):  
Zoubida Dendani-Chadi ◽  
Khelaf Saidani ◽  
Loubna Dib ◽  
Fayçal Zeroual ◽  
Faouzi Sammar ◽  
...  
Keyword(s):  
Univariate Analysis ◽  
Indirect Costs ◽  
Dairy Farms ◽  
Site Investigation ◽  
Cross Sectional Study ◽  
Small Scale ◽  
Facility Design ◽  
Cross Sectional ◽  
Housing Management ◽  
Increased Risk

Background and Aim: This cross-sectional study aimed to analyze the associations between different types of housing, management, and facilities on the prevalence of lame, causing lesions in smallholder dairy farms in Algeria. Materials and Methods: The on-site investigation took place between December 2012 and May 2015. All cows were locomotion scored on a four-point scale, and foot lesions causing lame were diagnosed and recorded. Factors related to the farm and the cows' conditions were also assessed. The association between the possible risk factors and lame lesions was assessed using univariate analysis. Results: Of the 349 cows evaluated, 13% were lame (lameness score ≥2), with higher lameness values recorded for the hind feet than for the forefeet. Cows without lameness were classified as healthy. The two most frequent lesion diagnoses observed in lame cows were interdigital dermatitis/heel horn erosion (ID/HE; 39%) and interdigital phlegmon (IP; 35%), followed by traumatic lesions (T; 11%), digital dermatitis (DD; 8.7%), and laminitis-related diseases (L; 6.5%). The risk of being lame was increased in large herds with cows of the Holstein breed, and those in the third parity and above. Tie housing, concrete floor, concentrate feeding, zero-grazing, and the use of foot trimming occasionally were associated with increased risk for the presence of lame lesions. The region and footbathing frequency had no association with the prevalence of lame lesions (p≥0.05). Conclusion: These results have important implications; they indicate that several aspects of housing, management, and facility design are common protective factors for the prevalence of lame lesions. These factors should be maintained correctly to not only reduce the number of lame cows in these herds but also decrease the direct and indirect costs associated with cases of lameness.

scholarly journals Restrictions on persons with disabilities for participating in family and community activities

2020 ◽  
Vol 22 (1) ◽  
pp. 1-7
Author(s):  
Floralinda García Puello ◽  
Yaneth Herazo Beltrán ◽  
Yisel Pinillos Patiño ◽  
Damaris Suárez Palacio ◽  
Egmar Longo Hull
Keyword(s):  
Univariate Analysis ◽  
Cross Sectional Study ◽  
Bivariate Analysis ◽  
Mobility Limitations ◽  
Functional Impairments ◽  
Cross Sectional ◽  
Persons With Disabilities ◽  
Community Activities ◽  
Probabilistic Sampling ◽  
Barriers To Access

Objective To identify the influence of functional impairments and limitations activities for persons with disabilities to participate in family and community activities. Methods This is a cross-sectional study with 4044 persons with disabilities, selected using probabilistic sampling and a door-to-door active search model in 5 towns in the District of Barranquilla. The data were processed with univariate analysis and bivariate analysis to determine the relationship between the study variables. Results 55.9% of the population were males, 41.6% were between 15 and 44 years of age, and 92.9% belonged to the lower socioeconomic stratum. 82.9% reported mobility limitations and 99% reported barriers to access non-formal learning activities, 98.6% to access public activities, and 97.5% to access productive activities. Individuals with that a lower limitation in exercising the power of reason, particularly thinking, can increase participation in activities with family and friends (OR, 0.8; 95% CI, 0.6–0.9), with the community (OR, 0.7; 95% CI, 0.6–0.9), religious or spiritual activities (OR, 0.8; 95% CI, 0.7–0.9). Conclusions There is a directly proportional relationship between structural impairment with the development of dependency and limited family, social, and work participation in the persons with disabilities.

scholarly journals EFFECT OF DAILY TRIP SYSTEM ON PT. X CONTRACTOR WORKER FATIGUE AT OFFSHORE SITE

2021 ◽  
Vol 5 (2) ◽  
pp. 73
Author(s):  
Desi Nuraini ◽  
Doni Hikmat Ramdhan
Keyword(s):  
Design Research ◽  
Univariate Analysis ◽  
Cross Sectional Study ◽  
Construction Workers ◽  
Bivariate Analysis ◽  
P Value ◽  
Offshore Platforms ◽  
Chi Square ◽  
Cross Sectional ◽  
Daily Trip

Background: PT. X implements a daily trip method that takes ±1,5 hours to arrive at the offshore platforms. Travel time that’s too long can cause fatigue. Purpose: Analyzing the effect of a daily trip system on PT. X contractor worker fatigue at offshore site. Method: This research was conducted at one of PT. X’s offshore Gresik Sites in June 2021 used Fatigue Assessment Scale (FAS) questionnaire with observational analytics method and cross-sectional study design. Research samples were taken from the population of 153 construction workers PT. X at offshore site. The data obtained were analyzed using quantitative approach, data analysis used univariate analysis and bivariate analysis, chi-square statistical test with significance value or confidence interval was 95% and error interval was 5%  (CI = 95% and α = 0.05). Result: PT. X Contractor workers at the offshore site had 85 workers (55.56%) that get fatigue. Statistical analysis test showed there was no significant relationship between a daily trip system with fatigue on PT. X Contractor workers at the offshore site (p-value = 0.140). Factors that affect fatigue on PT. X Contractor workers at the offshore site were age, body mass index, and workload (p-value successive were 0.047, 0.014, and 0.001). Conclusion: A daily trip system has no effect with fatigue on PT. X contractor worker at the offshore site, recommended for the contractor to improve the BMI and manage the workload so that its more evenly distributed.

Symptoms of Depression and Anxiety, and Screening for Mental Disorders in Migrainous Patients

Cephalalgia ◽  
2003 ◽  
Vol 23 (2) ◽  
pp. 79-89 ◽  
Author(s):  
F Kowacs ◽  
MP Socal ◽  
SC Ziomkowski ◽  
VF Borges-Neto ◽  
DP Toniolo ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Mental Disorders ◽  
Healthy Subjects ◽  
Univariate Analysis ◽  
Cross Sectional Study ◽  
Depression And Anxiety ◽  
Sectional Study ◽  
Cross Sectional ◽  
Symptoms Of Depression ◽  
Gender Education

The purpose of this clinic-based study was the assessment of symptoms of depression, anxiety, and non-specific psychiatric disorders amongst patients with migraine, compared with healthy subjects and with individuals with a non-neurological chronic disease. A cross-sectional study was carried out in which 178 individuals (migraine 51; psoriasis 35; healthy 92) were submitted to three scales: MADRS (depression), STAI-T (anxiety) and SRQ (screening for mental disorders). The subjects with migraine and psoriasis were from the Out-patient Clinics of Headache and of Dermatology, and the healthy volunteers were persons who were accompanying out-patients in the same hospital. Scores were analysed by MANOVA and by association analysis and logistic regression. Scores of all instruments were higher in the migrainous group, but the univariate analysis of association (using cut-offs) showed significance only for suspicion of mental disorders (SRQ). By logistic regression, variables with strongest association to migraine were gender, education, and SRQ in decreasing order.

scholarly journals Sex-Based Differences in the Association between Nutrition Label Awareness and the Prevalence of Atopic Dermatitis: A Cross-Sectional Survey

Healthcare ◽  
2020 ◽  
Vol 8 (3) ◽  
pp. 210
Author(s):  
Soo Jin Kwon ◽  
Yoonjung Kim
Keyword(s):  
Atopic Dermatitis ◽  
Food Selection ◽  
Univariate Analysis ◽  
Cross Sectional Study ◽  
Cross Sectional Survey ◽  
Nutrition Label ◽  
Cross Sectional ◽  
Nutrition Labels ◽  
Men And Women ◽  
The Relationship

Atopic dermatitis is a chronic allergic disease with multifactorial causation. Although its association with diet has been demonstrated, it remains unclear whether the prevalence of atopic dermatitis among adults is associated with nutrition label awareness. Nutrition label awareness indicates knowledge of the existence of nutrition labels on processed food, and the use of them for food selection. In this cross-sectional study, we analyzed the relationship between nutrition label awareness and the prevalence of atopic dermatitis among men and women using data from the Korean National Health and Nutrition Examination Survey VI (2013–2015), including a nationally representative sample of 13,505 Korean adults (aged > 19 years). The relationship between the prevalence of atopic dermatitis and nutrition label awareness was evaluated using t-tests, χ2 tests and multivariate adjusted logistic regression analysis. Although univariate analysis showed that atopic dermatitis was associated with nutrition label awareness in both men and women, after adjustment for covariates, there was no significant association among men. The significant association between the prevalence of atopic dermatitis and nutrition label awareness among women reveals a sex-based difference in this relationship in adults, and atopic dermatitis may be managed and prevented among women by targeted education regarding nutrition labels and diet.

scholarly journals Specialty Physician Designation in Referrals from a Vertically Integrated PCMH

2019 ◽  
Vol 6 ◽  
pp. 233339281985038
Author(s):  
Andrew D. Schreiner ◽  
Keri T. Holmes-Maybank ◽  
Jingwen Zhang ◽  
Justin Marsden ◽  
Patrick D. Mauldin ◽  
...  
Keyword(s):  
Medical Home ◽  
Univariate Analysis ◽  
Cross Sectional Study ◽  
Individual Characteristics ◽  
Patient Centered Medical Home ◽  
Patient Centered ◽  
Cross Sectional ◽  
Medical Specialties ◽  
The Individual

Introduction: Primary care referrals to specialty physicians once relied upon the medical skill of the specialist, the quality of past communication, and previous consultative experiences. As health systems vertically integrate, patterns of specialty physician referral designation are not known. Methods: This cross-sectional study from a patient-centered medical home (PCMH) evaluated the proportion of referrals with named specialists. All outpatient specialty referrals from the PCMH between July and December of 2014 were eligible for inclusion, and 410 patients were randomly selected for chart review. The outcome of interest was specialty physician designation. Other variables of interest included PCMH provider experience, the reason for referral, and time to specialty visit. Univariate analysis was performed with Fisher exact tests. Results: Of 410 specialty referrals, 43.7% were made to medical specialties, 41.7% to surgical specialties, and 14.6% to ancillary specialties. Resident physicians placed 224 referrals (54.6%), faculty physicians ordered 155 (37.8%), and advanced practice providers ordered 31 (7.6%). Only 11.2% of the specialty referral orders designated a specific physician. No differences appeared in the reason for referral, the referral destination, the proportion of visits scheduled and attended, or the time to schedule between those referrals with and without specialty physician designation. Faculty physicians identified a specific specialist in 21.4% of referrals compared to residents doing so in 4.9% ( P < .0001). Conclusion: Patient-centered medical home referrals named a specific specialty physician infrequently, suggesting a shift from the historical reliance on the individual characteristics of the specialist in the referral process.

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