scholarly journals Association of anticardiolipin IgM antibody with preeclampsia

2018 ◽  
Vol 11 (2) ◽  
pp. 126
Author(s):  
Sharmin Khanam ◽  
Parveen Fatima ◽  
Begum Nasrin ◽  
Md. Mozammel Hoque

<p class="Abstract">The objective of this study was to evaluate association of anticardiolipin IgM antibody with preeclampsia among the 70 pregnant women having preeclampsia from March 2016 to February 2017. Equal number of age matched normotensive healthy pregnant women was selected as control. Demographic, obstetric and relevant laboratory data were collected and compared between the two groups. The level of anticardiolipin IgM antibody was significantly higher in preeclamptic women than in normal pregnant (mean 8.7 vs 5.8 U/mL, p&lt;0.001). Even in categorical distribution when the value was considered as positive by assessing a cut-off, cases had three times more chance to have positive level of anticardiolipin IgM antibody than controls (OR=3.3, 95% CI=1.1-9.6, p=0.046). Pearson’s correlation test revealed that both systolic and diastolic blood pressure had a positive correlation with the level of anticardiolipin IgM antibody. (p&lt;0.05). In conclusion, this study shows that anticardiolipin IgM antibody was associated with preeclampsia. The level of this anticardiolipin IgM antibody is directly proportional to the severity of preeclampsia and both systolic and diastolic blood pressure.</p>

2021 ◽  
Vol 49 (1) ◽  
pp. 60-66
Author(s):  
Onur Güralp ◽  
Nevin Tüten ◽  
Koray Gök ◽  
Kübra Hamzaoglu ◽  
Huri Bulut ◽  
...  

AbstractObjectivesTo evaluate the serum levels of the serine proteinase inhibitor kallistatin in women with preeclampsia (PE).MethodsThe clinical and laboratory parameters of 55 consecutive women with early-onset PE (EOPE) and 55 consecutive women with late-onset PE (LOPE) were compared with 110 consecutive gestational age (GA)-matched (±1 week) pregnant women with an uncomplicated pregnancy and an appropriate for gestational age fetus.ResultsMean serum kallistatin was significantly lower in women with PE compared to the GA-matched-controls (27.74±8.29 ng/mL vs. 37.86±20.64 ng/mL, p<0.001); in women with EOPE compared to that of women in the control group GA-matched for EOPE (24.85±6.65 ng/mL vs. 33.37±17.46 ng/mL, p=0.002); and in women with LOPE compared to that of women in the control group GA-matched for LOPE (30.87±8.81 ng/mL vs. 42.25±22.67 ng/mL, p=0.002). Mean serum kallistatin was significantly lower in women with EOPE compared to LOPE (24.85±6.65 ng/mL vs. 30.87±8.81 ng/mL, p<0.001). Serum kallistatin had negative correlations with systolic and diastolic blood pressure, creatinine, and positive correlation with GA at sampling and GA at birth.ConclusionsSerum kallistatin levels are decreased in preeclamptic pregnancies compared to the GA-matched-controls. This decrease was also significant in women with EOPE compared to LOPE. Serum kallistatin had negative correlation with systolic and diastolic blood pressure, creatinine and positive correlation with GA at sampling and GA at birth.


2015 ◽  
Vol 116 (9/10) ◽  
pp. 564-577 ◽  
Author(s):  
RISHABH SHRIVASTAVA ◽  
Preeti Mahajan

Purpose – The purpose of this paper is twofold. First, the study aims to investigate the relationship between the altmetric indicators from ResearchGate (RG) and the bibliometric indicators from the Scopus database. Second, the study seeks to examine the relationship amongst the RG altmetric indicators themselves. RG is a rich source of altmetric indicators such as Citations, RGScore, Impact Points, Profile Views, Publication Views, etc. Design/methodology/approach – For establishing whether RG metrics showed the same results as the established sources of metrics, Pearson’s correlation coefficients were calculated between the metrics provided by RG and the metrics obtained from Scopus. Pearson’s correlation coefficients were also calculated for the metrics provided by RG. The data were collected by visiting the profile pages of all the members who had an account in RG under the Department of Physics, Panjab University, Chandigarh (India). Findings – The study showed that most of the RG metrics showed strong positive correlation with the Scopus metrics, except for RGScore (RG) and Citations (Scopus), which showed moderate positive correlation. It was also found that the RG metrics showed moderate to strong positive correlation amongst each other. Research limitations/implications – The limitation of this study is that more and more scientists and researchers may join RG in the future, therefore the data may change. The study focuses on the members who had an account in RG under the Department of Physics, Panjab University, Chandigarh (India). Perhaps further studies can be conducted by increasing the sample size and by taking a different sample size having different characteristics. Originality/value – Being an emerging field, not much has been conducted in the area of altmetrics. Very few studies have been conducted on the reach of academic social networks like RG and their validity as sources of altmetric indicators like RGScore, Impact Points, etc. The findings offer insights to the question whether RG can be used as an alternative to traditional sources of bibliometric indicators, especially with reference to a rapidly developing country such as India.


Vascular ◽  
2018 ◽  
Vol 27 (2) ◽  
pp. 128-134 ◽  
Author(s):  
Jeeeun Park ◽  
Jinhae Kim ◽  
Subin Hwang ◽  
Mi Kyoung Lee ◽  
Hye Ryoun Jang ◽  
...  

Objectives Arteriovenous graft for hemodialysis shows poorer outcomes than arteriovenous fistula, due to frequent stenosis and thrombosis. We investigated arteriovenous graft patency outcomes and prognostic factors for these outcomes. Methods We included a single-center cohort of patients receiving arteriovenous graft for hemodialysis access from 2010 to 2014. Demographics, laboratory data, comorbidities, and medications were collected from medical records. Surgical factors related to graft operation including the type and diameter of connected vessels, graft location, and type of operation (elective or emergency) were also recorded. Outcomes included primary and secondary patency. Survival analysis was conducted using the Kaplan-Meier method; univariate and multivariate analyses were used to evaluate the prognostic factors. Results Data from 225 grafts were analyzed. During the follow-up period (mean: 583 days, range: 1–1717 days), 138 (61%) grafts required intervention and 46 (20%) permanently failed. Primary patency at one, two, and three years was 42%, 20%, and 16%, respectively. Secondary patency at one, two, and three years was 85%, 72%, and 64%, respectively. Multivariate analysis showed that primary patency was negatively associated with increasing age and location of vessel anastomosis (reference-brachiobrachial anastomosis; brachiobasilic – HR, 0.569; 95% CI, 0.376–0.860; p = 0.007; brachioaxillary anastomosis – HR 0.407; 95% CI, 0.263–0.631; p < 0.0001); secondary patency was positively associated with diastolic blood pressure, serum albumin level, and hemoglobin over 10 g/dL. Adverse events other than stenosis or thrombosis, such as infection/inflammation or pseudoaneurysm were observed in approximately 20% of grafts. Conclusions Factors associated with diminished primary arteriovenous graft patency included increased patient age and location of vessel anastomosis (brachiobrachial type compared to brachiobasilic or brachioaxillary type); diminished secondary patency was associated with low diastolic blood pressure, low serum albumin, and hemoglobin level under 10 g/dL. Among these factors, diastolic blood pressure, serum albumin, and hemoglobin level may be modifiable and could improve arteriovenous graft patency outcomes.


Author(s):  
Anders Åberg

AbstractStandardized conditions for blood pressure measurements and strict definitions of systolic and diastolic blood pressure are essential for a consequent management of hypertension during pregnancy. In Sweden, it has been agreed to measure blood pressure with the pregnant women sitting in upright position. Home-monitoring of blood pressure is recommended in women at risk of preeclampsia.


2021 ◽  
Vol 8 (1) ◽  
pp. 24-31
Author(s):  
Maslahatul Inayah ◽  
Tri Anonim

Maternal Mortality Rate (MMR) can be a measuring tool to determine the quality of health services both during pregnancy and postpartum. Pregnant women with preeclampsia can cause complications that lead to increased maternal mortality and perinatal mortality. There are several attempts to control high blood pressure. This method can use pharmacological or non pharmacological.  The purpose of this study was to determine the effectiveness of warm water foot soak therapy on changes in blood pressure reduction of preeclamptic pregnant women. This type of research is a quantitative study with aresearch quasi-experimentaldesign, with adesign approach pre and post test in the intervention group and the conMtrol group. The sample for each group is 10 people, so that the total number of samples is 20 respondents.Bivariate analysis was performed using the Wilxocon test because the data distribution was not normal and the Mann-Whitney Test to determine the difference before and after the intervention was given.The results of the bivariate analysis showed that there was an effect of giving warm water foot soaking therapy to changes in the decrease in systolic and diastolic blood pressure of preeclamptic pregnant women with a value of p = 0.004 and p = 0.011 and there were differences in changes in the decrease in systolic and diastolic blood pressure between the intervention group and the control group. p = 0.001 and p = 0.007.


2016 ◽  
Vol 2 (1) ◽  
pp. 32-40
Author(s):  
Very Julianto ◽  
Pipih Muhopila

The research aimed to understand the relation between fasting and the anger regulation. Subject’s researchs were 100 students of UIN Sunan Gunung Djati Bandung taken by random sampling. Subjects consist of 43 man and 57 woman. This research used quantitative method. Data was collected by questionare, and method of analysis was Pearson’s correlation test. The result has shown there is relation between fasting and the anger regulation with scale of correlation was 54%. Subject that often fasting, carbohydrate input was lower so that the subject had high level of anger regulation.


Author(s):  
Miftah Nurlaily El Akhlaq ◽  
Suharyo Hadisaputro ◽  
Suhartono . ◽  
Sri Sumarni ◽  
M. Choiroel Anwar

Bay leaf (Syzygiumpolyanthum) or Daun Salam is one of the plants that has many benefits, one of them is to reduce blood pressure. The aim of this study is to prove the effect of adding nanoparticles supplementation of bay leaf (Syzygiumpolyanthum) to systolic and diastolic blood pressure in pregnancy hypertension.The study was quasi-experiment. 39 respondents were divided into 19 pregnant women in intervention group and 20 pregnant women in the control group. The intervention was given for 14 days by consumingnifedipine 10mg plus 80mg bay leaf nanoparticle capsules to the intervention group.The results of data analysis showed a decrease in systolic blood pressure (p = 0.000) and diastolic blood pressure (p = 0.004) when compared with the control group, which means that there were differences in the mean systolic and diastolic blood pressure between the two groups after treatment. The addition of bay leaf nanoparticle supplementation 1x80 mg for 14 days affected the decrease in systolic and diastolic blood pressure in pregnancy hypertension. So that the supplementation of bay leaf nanoparticles can be used as adjunctive therapy in pregnancy hypertension


2020 ◽  
Vol 14 (2) ◽  
pp. 82-85
Author(s):  
Swapna Biswas Joy ◽  
Md Rabiul Islam ◽  
Monika Khandoker ◽  
Ananta Kumar Biswas

Preeclampsia is one of the most important pregnancy disorder, diagnosed with hypertension and proteinuria. It is the leading cause of fetal and maternal morbidity and mortality. This cross-sectional study was conducted in 100 pregnant women, of them, 50 were diagnosed cases of preeclampsia and 50 were normal pregnant women attended in the Gynaecology and Obstetrics department of Dhaka Medical College Hospital, Dhaka, during July 2016 to June 2017. Five ml fasting blood sample was collected and was analysed for triglyceride using standard enzymatic method. Mean value of triglyceride was compared between two groups by student unpaired t-test and the triglyceride level was correlated with systolic, diastolic blood pressure and urine albumin in preeclamptic patient was correlated by Pearson's correlation coefficient test. A p-value was considered to be statistically significant at 0.05 at 95% confidence interval. Statistically significant difference of serum triglyceride level was found in preeclamptic women and normal pregnant women (p<0.05). The level was 248.90±31.36 mg/dl in preeclampsia and 197.00±27.04 mg/dl in normal pregnant women respectively. Serum triglyceride was positively correlated with systolic, diastolic blood pressure and urine albumin in preeclamptic women. Faridpur Med. Coll. J. Jul 2019;14(2): 82-85


2019 ◽  
Vol 17 (Sup5) ◽  
pp. S18-S22
Author(s):  
Hossein Rafiei ◽  
Kazem Hosseinzadeh ◽  
Mohammad Javad Hoseinabadi-Farahani ◽  
Ladan Naseh ◽  
Ali Razaghpoor ◽  
...  

Aim: The aim of this study was to investigate the relationship between psychological problems and spiritual wellbeing in Iranian stoma patients. Methods: This descriptive-analytic study was conducted on 70 stoma patients who were enrolled through a convenience sampling method. Depression, anxiety and stress among patients were analysed using Depression, Anxiety and Stress Scale (DASS-21) questionnaire and their spiritual wellbeing was analysed using the Spiritual Wellbeing Scale (SWS). Pearson's correlation test was used to determine the relationship between depression, stress and anxiety with the total spiritual wellbeing and its dimensions. Results: The results of Pearson's correlation test showed that there was an inverse and significant correlation between stress (RR -0.728; P<0.001), anxiety (RR -0.721; P<0.001) and depression (RR -0.740; P<0.001) with the total score for spiritual wellbeing. Conclusion: These results demonstrated that there is a relationship between psychological problems and spiritual wellbeing in ostomates. That is, patients with higher spiritual wellbeing reported lower levels of psychological problems. The results of the present study can be used for holistic nursing care in these patients.


1997 ◽  
Vol 78 (5) ◽  
pp. 737-750 ◽  
Author(s):  
Kazue Itoh ◽  
Terukazu Kawasaki ◽  
Motoomi Nakamura

In a double-blind, placebo-controlled study, thirty-three subjects were allocated to undergo either a 4-week treatment with oral Mg supplementation (Mg(OH)2; 411–548 mg Mg/d) or a placebo. The urinary excretion of Mg increased significantly in both the first 2 weeks and the following 2 weeks of Mg supplementation, while the urinary Na excretion also increased significantly over the experimental period. The systolic and diastolic blood pressure values decreased significantly in the Mg group, but not in the placebo group. The urinary aldosterone excretion and packed cell volume increased significantly during the last 2 weeks of the experimental period compared with the run-in period and first 2 weeks of supplementation. There was a statistically significant positive correlation between the values for urinary noradrenaline excretion and diastolic blood pressure at the end of the supplementation period (both expressed as a percentage of the run-in value). Statistically significant increases in lecithin-cholesterol acyltransferase (EC2.3.1.43; LCAT), HDL-cholesterol and apolipoprotein AI were also observed after Mg supplementation. A significant positive correlation was observed between the levels of LCAT and urinary Mg excretion for the experimental period (expressed as a percentage of the run-in value). The total cholesterol: HDL-cholesterol ratio decreased significantly during the last 2 weeks of Mg supplementation compared with the first 2 weeks and the run-in periods, but this did not occur in the placebo group. These results suggest that Mg supplementation may lower blood pressure through the suppression of the adrenergic activity and possible natriuresis, while also improving the serum lipids through the activation of LCAT in human subjects.


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