scholarly journals Low Serum Ferritin is a Risk for Febrile Convulsion in Children

2017 ◽  
Vol 11 (2) ◽  
pp. 44-46
Author(s):  
Aloke Kumar Saha ◽  
Md Kamrul Hassan ◽  
Lakshman Chandra Kundu ◽  
Shyamal Kumar Saha ◽  
Poly Begum ◽  
...  
Keyword(s):  
Serum Ferritin ◽  
Serum Iron ◽  
Case Control Study ◽  
Febrile Convulsion ◽  
Febrile Seizures ◽  
Case Control ◽  
Control Group ◽  
College Hospital ◽  
Medical College ◽  
Control Study

Iron deficiency anaemia and febrile seizures are two common diseases in children worldwide as well as in developing country. A prospective case-control study was carried out in the Department of Paediatrics, Faridpur Medical College Hospital. The study was done during the period from January'2015 to September'2015 with 50 children with first simple febrile seizure as cases and other 50 controls. There were no significant differences in terms of ESR, WBC, platelets, RBC, MCHC, and TIBC levels between the cases and the control group. HB, HCT, MCH, mean serum ferritin and serum iron, were significantly low in the febrile convulsion group as compared to control group.Faridpur Med. Coll. J. Jul 2016;11(2): 44-46

scholarly journals Association of Ankle Brachial Pressure Index (ABPI) in Patients with Ischemic Stroke: A Case-Control Study

2013 ◽  
Vol 29 (1) ◽  
pp. 31-42
Author(s):  
Mohammad Selim Shahi ◽  
Aminur Rahman ◽  
Md Shaheen Wadud ◽  
Ak Takib Uddin Ahmed ◽  
Uttam Kumar Saha ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Case Control Study ◽  
Epidemiological Studies ◽  
Case Control ◽  
Control Group ◽  
Case Group ◽  
Medical College ◽  
The Difference ◽  
Relationship Of ◽  
Control Study

Background: Several epidemiological studies have identified the association of abnormal ABPI with ischemic stroke. So the goal of this study was to determine the actual relationship of ABPI with ischemic stroke in the context of our country. Materials and Methods: This case control study was carried out in the Department of Neurology, Sir Salimullah Medical College and Mitford Hospital, Dhaka, Bangladesh. ABPI was measured by Doppler ultrasound machine of 100 patients who were admitted to the Mitford Hospital during the study period. Among them 50 patients with Ischemic stroke, confirmed by CT/MRI scan of brain were considered as ‘case’ and 50 age- sex matched individuals with one or more vascular risk factors (VRF) but without stroke were considered as ‘control’. Then the results of ABPI were compared between the two groups. Results: Among the 50 patients with ischemic stroke (case group) , 74% had normal ABPI and 26% had ABPI< 0.9; on the other hand among 50 age and sex matched individuals (control group) 90% had normal ABPI and 10% had ABPI <0.9. The difference was statistically significant between two groups (p=<0.05).This association remained significant even after adjustment for potential confounders (age, gender, high BMI, hypertension, diabetes mellitus, hyperlipidemia, smoking, ischemic heart disease and family history) in a multiple logistic regression model. Conclusion: The incidence of low ABPI is significantly higher in ischemic stroke patients than the age- sex matched control. Bangladesh Journal of Neuroscience 2013; Vol. 29 (1) : 31-42

scholarly journals Diabetes and hypertension in patients with psoriasis: a cross sectional and case control study in a tertiary care hospital of Bangladesh

2021 ◽  
Vol 9 (8) ◽  
pp. 2217
Author(s):  
Samira Jamal ◽  
Sheikh Anwarul Karim ◽  
Sheikh Mahee Ridwan Raihan ◽  
Rajat Biswas ◽  
Mansurul Alam
Keyword(s):  
Case Control Study ◽  
Skin Diseases ◽  
Tertiary Care ◽  
Case Control ◽  
Control Group ◽  
Care Hospital ◽  
College Hospital ◽  
Cross Sectional ◽  
Increased Risk ◽  
Control Study

Background: In this study our main goal was to evaluate the association of psoriasis as a risk predictor for the occurrence of diabetes mellitus (DM) and hypertension (HTN).Methods: This case control study was carried out in the department of dermatology and venereology, Chittagong medical college hospital (CMCH), Chittagong, Bangladesh from 15 June 2011 to 14 May 2012. Where 60 patients with psoriasis and 60 patients with skin diseases other than psoriasis were included according to availability within the study period.Results: During study, among the psoriatic patients, most of the patients with DM and HTN had body mass index (BMI) within normal limit. During analysis of different clinical findings in psoriatic patients scaling was present in all the cases followed by Auspitz sign, koebnerization, itching, scalp involvement and nail changes. Patients with psoriasis were found to have higher incidence of DM and HTN in comparison to their non-psoriatic control group. It was also observed that psoriatic patients having DM and HTN had longer duration of diseases (p<0.05).Conclusions: In conclusion, our study indicates that patients with psoriasis have an increased risk of DM and HTN, confirming the findings from previous several case control and cross sectional studies. These data illustrate the importance of considering psoriasis as a systemic disorder rather than simply a skin disease. Awareness of concurrent diseases will provide the clinician an opportunity of screening .for others systemic diseases.

scholarly journals Prophylactic Iron Supplementation in Pregnancy and its Implications in Development of Pre-eclampsia: A Case-control Study

2021 ◽  
Author(s):  
Lakbir Singh ◽  
Ajit Thakur ◽  
Fayyaz Mukarab Khan ◽  
Minakshi Misra ◽  
Saurabh Singh
Keyword(s):  
Serum Ferritin ◽  
Serum Iron ◽  
Iron Supplementation ◽  
Case Control Study ◽  
Case Control ◽  
Research Centre ◽  
Ferritin Concentration ◽  
Iron Deficient ◽  
Increased Risk ◽  
Control Study

Introduction: Pre-eclampsia is a serious complication of pregnancy and is associated with increased maternal and perinatal morbidity and mortality. Increased iron and ferritin concentration is associated to a higher risk of pre-eclampsia and prophylactic iron supplementation can sometimes be harmful to pregnant women who are otherwise not iron deficient. Aim: To analyse serum iron, serum ferritin, serum Transferrin Receptor (sTFR) levels, Total Iron Binding Capacity (TIBC) among iron supplemented pre-eclamptic cases and normotensive pregnant controls. Materials and Methods: This prospective, observational, case- control study was conducted in Jaipur National University Institute of Medical Sciences and Research Centre (JNUIMSRC), Jaipur, Rajasthan, India for a period of one year from (February 2019-January 2020). A total of 200 pregnant females, all on iron supplementation during the course of their pregnancy, 100 in pre-eclampsia group (case group); 100 in normotensive group (control group), in third trimester and between 18- 45 years of age were enrolled in the study. Serum iron, serum ferritin, sTFR and TIBC were estimated using fully automated analysers. Results: Median Interquartile Range (IQR) of serum ferritin levels in cases were higher than the controls [41 (30-70) vs 24 (17-44); p<0.001]. Serum ferritin in cases were also found to correlate positively with systolic (r=0.37, p=0.001) Blood Pressure (BP) whereas TIBC correlated negatively with diastolic BP (r=-0.238, p-value=0.017). The median IQR differences of TIBC values among cases and controls were insignificant {485 (404-523) vs 493 (448- 544)} and differences of median IQR of sTFR values among cases and controls were significant {8.5 (7-9) vs 8.9 (8-10)}. Subjects with serum feritin levels >40 ng/mL had three times increased risk of PE (Odds ratio=3, 95% Cl=1.571-5.157). Conclusion: Elevated serum ferritin, decreased sTFR levels and correlation of Ferritin and TIBC to BP in pre-eclampsia compels us to put cautionary remarks over testing these parameters before continuing with iron supplements. This may prevent a possible iron related added complications in pre-eclampsia and help clinicians decide about restricting/lowering iron supplement doses in case a situation of iron overload arise.

scholarly journals Iron deficiency in febrile seizures: a prospective case control study

2020 ◽  
Vol 7 (12) ◽  
pp. 2267
Author(s):  
Vasanth N. Kumar ◽  
Farogh Hassan ◽  
Lata Jha ◽  
Abnish Kumar ◽  
Chandreyi Bandopadhyay ◽  
...  
Keyword(s):  
Iron Deficiency ◽  
Serum Ferritin ◽  
Mean Corpuscular Volume ◽  
Case Control Study ◽  
Febrile Seizures ◽  
Case Control ◽  
Care Hospital ◽  
Age Group ◽  
Corpuscular Volume ◽  
Control Study

Background: The objective of the study was to evaluate the role of iron deficiency in febrile seizures.Methods: Case control study conducted at Pediatric department of Tertiary care hospital. A total 70 cases and 70 controls were included in the study. Consecutive cases and controls were selected. Cases were children of age group 6 months to 5 years with simple febrile seizures and controls were children of same age group with short febrile illness without any seizures. After consent, detailed history was taken and clinical examination were carried out for both groups. Blood investigations were done to diagnose iron deficiency in both cases and controls. Iron deficiency was diagnosed as per WHO criteria haemoglobin <11 g/dl in cases <5 years mean corpuscular volume<70 fl, mean corpuscular haemoglobin <27 pg and serum ferritin<30 microgram/dl.Results: Mean corpuscular volume was less than 70 fl/ml in 51% cases and 31% controls and mean corpuscular hemoglobin was less than 27 pg/ml in 84% cases and 40% of controls indicating statistically significant association of MCV and MCH between cases and controls .Serum ferritin was less than 30 ng/ml in 44% in cases as compared to 26% of controls, there was statistically significant difference between serum ferritin levels in cases and controls. From the above findings, study showed statistically significant association between iron deficiency anaemia and febrile seizures (p value <0.01; OR- 8.05 (3.6-17.93) (df-1).Conclusions: Iron deficiency is a major risk factor for simple febrile seizures in age group of 6 months to 60 months.

scholarly journals THE HORMONAL CHANGES AMONG NIGERIAN WOMEN WITH EPILEPSY

2020 ◽  
Vol 10 ◽  
pp. 32
Author(s):  
Bamidele Sanya Osalusi ◽  
Lukman Ogunjimi ◽  
Joseph Yaria ◽  
Ayotunde Ale ◽  
Olawale Ogunsemi ◽  
...  
Keyword(s):  
Case Control Study ◽  
Case Control ◽  
Control Group ◽  
Hormonal Changes ◽  
College Hospital ◽  
Nigerian Women ◽  
Symptomatic Epilepsy ◽  
Hormonal Evaluation ◽  
The University ◽  
Control Study

This study aims to compare the sex hormones between women with epilepsy (WWE) and their agematched controls. We postulated that a difference in etiology, may be associated with an unexpected hormonal profile.  A case control study carried out at the University College Hospital, Ibadan, South western, Nigeria involving seventy-five WWE and age-matched controls. Blood samples for hormonal evaluation follicle stimulating hormone (FSH), luteinizing hormone (LH), estrogen, progesterone and testosterone were taken twice from all the participants during their menstrual cycle. WWE had lower BMI (p: 0.004), cycle length (p: 0.014) and more menstrual pattern irregularities (p< 0.001.) In the pre-ovulatory phase, WWE had lower FSH levels when compared with controls, (p: 0.012). Further stratification shows a higher FSH levels among WWE on medication, (p: 0.003).In the mid-luteal phase, FSH level was lowest in WWE not on medication, WWE on medication had higher levels but lower when compared to the control group, p: 0.002. FWE had lower progesterone levels when compared with the control group, (p: 0.004) with no difference with use of AEDs. Testosterone levels were lower among those with symptomatic epilepsy, (p:0.012)WWE had lower progesterone, lower FSH and more menstrual abnormalities, compare to controls in our population.

scholarly journals Association of Ankle Brachial Pressure Index (ABPI) in Patients with Ischemic Stroke : A Case Control Study

2013 ◽  
Vol 12 (3) ◽  
pp. 27-33
Author(s):  
Mohammad Selim Shahi ◽  
Aminur Rahman ◽  
Md Shaheen Wadud ◽  
Uttam Kumar Saha ◽  
AK Takib Uddin Ahmed ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Case Control Study ◽  
Epidemiological Studies ◽  
Case Control ◽  
Control Group ◽  
Case Group ◽  
Medical College ◽  
The Difference ◽  
Relationship Of ◽  
Control Study

Background: Several epidemiological studies have identified the association of abnormal ABPI with ischemic stroke. So the goal of this study was to determine the actual relationship of ABPI with ischemic stroke in the context of our country. Methods: This case control study was carried out in the Department of Neurology, Sir Salimullah Medical College and Mitford Hospital, Dhaka, Bangladesh. ABPI was measured by Doppler ultrasound machine of 100 patients who were admitted to the Mitford Hospital during the study period. Among them 50 patients with Ischemic stroke, confirmed by CT/MRI scan of brain were considered as ‘case’ and 50 age-sex matched individuals with one or more vascular risk factors (VRF) but without stroke were considered as ‘control’. Then the results of ABPI were compared between the two groups. Results: Among the 50 patients with ischemic stroke (case group), 74% had normal ABPI and 26% had ABPI< 0.9; on the other hand among 50 age and sex matched individuals (control group) 90% had normal ABPI and 10% had ABPI <0.9. The difference was statistically significant between two groups. (p=<0.05).This association remained significant even after adjustment for potential confounders (age, gender, high BMI, hypertension, diabetes mellitus, hyperlipidemia, smoking, ischemic heart disease and family history) in a multiple logistic regression model. Conclusion: The incidence of low ABPI is significantly higher in ischemic stroke patients than the age- sex matched control. Chattagram Maa-O-Shishu Hospital Medical College Journal Volume 12, Issue 3, September 2013: 27-33

scholarly journals Comparative Study of Malondialdehyde, Superoxide Dismutase and Glutathione Peroxidase in Urolithiasis Patients: A Case Control Study

2021 ◽  
pp. 208-213
Author(s):  
Rakesh Kumar Jha ◽  
Ranjit Ambad ◽  
Ajonish Kamble ◽  
Yashwant Lamture
Keyword(s):  
Superoxide Dismutase ◽  
Glutathione Peroxidase ◽  
Comparative Study ◽  
Case Control Study ◽  
Tubular Epithelial Cell ◽  
Case Control ◽  
Control Group ◽  
Medical College ◽  
Renal Tubular ◽  
Control Study

Background: Urolithiasis i.e. stone firming disease in the urinary passages is one of the frequently encountered diseases in man. Perhaps the disease is as ancient as the man himself as has been revealed by the archaeological excavation done in different parts of the world such as in Egypt. Aim: Comparative Study of Malondialdehyde, Superoxide Dismutase and Glutathione Peroxidase in Urolithiasis Patients: A Case Control Study Materials and Methods: The study was carried out in the Department of Biochemistry, Datta Meghe Medical College Nagpur in collaboration with Department of Surgery, Division of Urology and Department of Pharmacology. Results: The urolithiasis patients have shown a marked increase in plasma MDA levels. There was a significant increase in the values of superoxide dismutase in patients suffering from urolithiasis (6.26 ± 0.86 µmol/l RBC lysate) as compared to the normal control values (3.40 ± 1.09 µmol/l RBC lysate) in human volunteers (p<0.01).A significantly decreased value of glutathione peroxidase has been observed in patients suffering from urolithiasis as compared to the control group. Conclusion: Enhanced SOD can reduce the formation of Calcium Oxalate crystals and reduce the damage of renal tubular epithelial cell.

scholarly journals The association between melasma and iron profile: a case-control study

2020 ◽  
Vol 9 (2) ◽  
Author(s):  
Azadeh Goodarzi ◽  
Elham Behrangi ◽  
Afsaneh Sadeghzadeh Bazargan ◽  
Masoomeh Rohaninasab ◽  
Fatemeh Sadat Hosseini-Baharanchi ◽  
...  
Keyword(s):  
Vitamin B12 ◽  
Serum Iron ◽  
Case Control Study ◽  
Case Control ◽  
Deficiency Anemia ◽  
Control Group ◽  
Normal Range ◽  
Serum Parameters ◽  
Iron Profile ◽  
Control Study

Background — Melasma is a chronic acquired localized hypermelanosis, causing aesthetic problem for women and impairing their quality of life. Evidence has suggested that hyperpigmentation can occur as a result of iron deficiency anemia and vitamin B12 deficiency. Aim — We aimed to evaluate the serum parameters of iron profile in melasma patients. Material and Methods — This case-control study investigated 51 adult non pregnant women with melasma, compared with 51 controls, from patients referred to the Hospital, Tehran, Iran, 2017–2018. Melasma was diagnosed clinically according to the melasma area and severity index (MASI) score was calculated and recorded by the physician. The groups were compared in terms of vitamin B12, folate, serum iron, hemoglobin (Hb), mean corpuscular volume (MCV), total iron binding capacity (TIBC), and ferritin. Results — The mean and standard deviation of the women’s age was 36.89±8.88 years, significantly higher in the group of patients with melasma. Comparing the serum parameters between the groups indicated no statistically significant difference in terms of mean levels of ferritin, Hb, MCV, iron, vitamin B12, TIBC, and folate. The women in melasma group had a higher frequency in below normal range of ferritin and serum iron compared to the control group. None of the serum parameters were correlated with MASI. Conclusion — The higher frequency of below normal range of ferritin and serum iron levels in women with melasma compared to the control group showed a possible association between these serum parameters and melasma.

Comorbid Risk Factors for Acute Stroke: A Case-Control Study in Tertiary Care Hospital of Bangladesh

2017 ◽  
Vol 2 (2) ◽  
pp. 84-88
Author(s):  
Salahuddin Feroz ◽  
Shahjada Selim ◽  
Afsar Ahammed ◽  
Rahat Afza Chowdhury ◽  
Shahabul Huda Chowdhury ◽  
...  
Keyword(s):  
Risk Factors ◽  
Acute Stroke ◽  
Case Control Study ◽  
Case Control ◽  
Medical College Hospital ◽  
Care Hospital ◽  
College Hospital ◽  
Medical College ◽  
History Of ◽  
Control Study

Background: There is a high prevalence of coexisting medical conditions in patients with acute stroke; therefore, clinical investigators often need to adjust for comorbidities when assessing the effect of those risk factors on patient outcome. Objective: This study aimed to determines comorbid risk factors in patients with acute stroke.Methodology: A hospital-based case control study was conducted in Shaheed Suhrawardy Medical College Hospital (ShSMCH) and Dhaka Medical College Hospital between January-June 2011. The cases and controls studied consisted of 175 hospitalized patients with stroke (confirmed by computed tomography scan) and 171 matched-age and sex controls that were hospitalized at the study hospital for condition other than stroke. After obtaining written informed consent from the patient or the closest attendant, all the information included to record were age, sex, monthly family income, family size, family history of CVD death, history of hypertension and diabetes mellitus, ECG change, aspirin intake, blood pressure and heart rate, waist and hip circumference and psychosocial factors. The edited data then analyzed by SPSS V. 16.Result: The most predictive independent variables were history of hypertension (OR 4.056), psychosocial stress (OR 4.90) and increased WHR (OR 3.806) were found significant risk factor for developing stroke. Conclusion: Therefore, to recognize comorbid risk factors and to treat them appropriately is the key to establish primary preventive strategies in non-stroke patients or secondary preventive measures to avoid recurrence in stroke victims. Journal of National Institute of Neurosciences Bangladesh, 2016;2(2): 84-88

Sign in / Sign up

Export Citation Format

Share Document