scholarly journals Pheochromocytoma – An Unusual Presentation – A Case Report

1970 ◽  
Vol 28 (2) ◽  
pp. 113-116
Author(s):  
Indrajit Prasad ◽  
Zafar Ahmed Latif ◽  
Faruque Pathan ◽  
SM Ashrafuzzaman ◽  
Firoz Amin
Keyword(s):  
Blood Pressure ◽  
Case Report ◽  
Blood Sample ◽  
Blood Sugar ◽  
Severe Headache ◽  
Insulin Hypoglycemia ◽  
Intravenous Glucose ◽  
Profuse Sweating ◽  
To Come ◽  
Very High

This case report is of a 50yrs old man who got admitted inBIRDEM Hospital in a state of unconsciousness for 5 hours.He is a known case of hypertension and diabetes mellitusfor the last 12 years and was on insulin. Hypoglycemia wasdetected, treated with intravenous glucose and the patientregained consciousness. On further query he complainedof repeated episodes of nausea, palpitation and sweatingfor the last 12 years. The episodes were initially labeled ashypoglycemia but blood sugar was never found inhypoglycemic range. The patient was on multipleantihypertensive medications but blood pressure wasuncontrolled. All the investigations were normal including24hrs urinary VMA, serum adrenalin and noradrenalinexcept ultrasonography of whole abdomen which showed amass measuring 72x 76 mm in left suprarenal region. Onenight the patient again developed palpitation, chestdiscomfort, severe headache and profuse sweating. Bloodpressure was recorded 240/160 mmHg. Blood sample wasdrawn for adrenalin, noradrenalin, 24hrs urine collectionwas done for VMA and was found very high. The patientwas diagnosed as having left adrenal pheochromocytoma.After controlling blood pressure and other preoperativepreparations left adrenalectomy was done. Histopathologyrevealed phaeochromocytoma. Per and postoperativeperiods were quite eventful. Blood pressure was normalwithout any antihypertensive drug during discharge. Thepatient was discharged with the advice to come for followup after 1 month.DOI: 10.3329/jbcps.v28i2.5371J Bangladesh Coll Phys Surg 2010; 28: 113-116

scholarly journals A case report of Morvan syndrome

2021 ◽  
Vol 2021 (8) ◽  
Author(s):  
Sokrat Xhaxho ◽  
Gentian Vyshka ◽  
Eti Muharremi ◽  
Jera Kruja
Keyword(s):  
Blood Pressure ◽  
Case Report ◽  
Clinical Picture ◽  
Pressure Fluctuations ◽  
High Dose ◽  
Left Forearm ◽  
Psychomotor Agitation ◽  
Profuse Sweating ◽  
Muscle Twitching ◽  
Electrophysiological Findings

ABSTRACT Authors describe the case of a 22-year-old Caucasian male who presented acutely with psychomotor agitation, insomnia and muscle twitching with painful cramps. Autonomic symptoms were as well present, with profuse sweating, blood pressure fluctuations and tachycardia. He presented a miliary rash in his left forearm as well as in the neck. Electromyography documented myokymic movements bilaterally at both gastrocnemii and pretibial muscles. Brain imaging had no abnormalities, and anti-LGI1 and anti-CASPR2 resulted positive; this data together with electrophysiological findings suggested a Morvan syndrome. High-dose steroid therapy and plasma exchange improved substantially the clinical picture of the patient.

Application of irrigation and negative pressure wound therapy (INPWT) to treat diabetic foot gangrene: a case report

WCET Journal ◽  
2019 ◽  
Vol 39 (3) ◽  
pp. 20-25
Author(s):  
Ai-hua Chen ◽  
Huiling Liu ◽  
Chunmei Zhang ◽  
Ping Zou
Keyword(s):  
Blood Pressure ◽  
Case Report ◽  
Blood Sugar ◽  
Negative Pressure ◽  
Diabetic Foot ◽  
Negative Pressure Wound Therapy ◽  
Treatment Process ◽  
Wound Therapy ◽  
Spread Of Infection

This case study summarises the treatment of a patient with diabetic foot gangrene. By undergoing irrigation and negative pressure wound therapy (INPWT) with moist dressing, foot amputation was avoided. The treatment process included: the comprehensive assessment of systemic and local condition; choosing suitable debridement such as sharp surgical debridement; preventing the spread of infection; applying INPWT to reduce endotoxin absorption; and active treatments of primary disease such as controlling blood sugar and blood pressure, and improving microcirculation and nutrition. After 2 months of vigorous INPWT, the patient’s wound bed improved. After the application of a moist dressing, the wound closed and healed successfully at 3 months.

Spline Longitudinal Multi-Response Model for the Detection of Lifestyle-Based Changes in Blood Glucose of Diabetic Patients

2021 ◽  
Vol 18 ◽  
Author(s):  
Anna Islamiyati
Keyword(s):  
Blood Pressure ◽  
Blood Glucose ◽  
Blood Sugar ◽  
Statistical Approach ◽  
Repeated Measurements ◽  
University Teaching ◽  
Diabetic Patients ◽  
Carbohydrate Diet ◽  
South Sulawesi ◽  
Very High

Background: Blood sugar and lifestyle problems have long been problems in diabetes. There has also been a lot of research on that. However, we see that diabetic patients are still increasing even though many patients are not aware of the start of the disease occurrence. Therefore, we consider it very important to examine these two main problems of diabetes by using a more flexible statistical approach to obtain more specific results regarding the patient's condition. Objective: The form of data for type 2 diabetes patients is repeated measurements so that it is approached through longitudinal studies. We investigated various intervals of pattern change that can occur in blood glucose, namely fasting, random, and 2 hours after meals based on blood pressure and carbohydrate diets in diabetic patients in South Sulawesi Province, Indonesia. Methods: This research is a longitudinal study proposing a flexible and accurate statistical approach. It is a weighted spline multi-response nonparametric regression model. This model is able to detect any pattern of changes in irregular data in large dimensions. The data were obtained from Hasanuddin University Teaching Hospital in South Sulawesi Province, Indonesia. The number of samples analyzed was 418 from 50 patients with different measurements. Results: The optimal spline model was obtained at 2 knots for blood pressure and 3 knots for carbohydrate diets. There are three blood pressure intervals that give different patterns of increase in patient blood glucose levels, namely below 126.6 mmHg, 126.6-163.3 mmHg, and above 163.3 mmHg. It was found that blood sugar rose sharply at blood pressure above 163.3 mmHg. Furthermore, there are four carbohydrate diet intervals that are formed, which are below 118.6 g, 118.6-161.8 g, 161.8-205 g, and above 205 g. The result is that blood sugar decreased significantly at intervals of carbohydrate diet 161.8-205 g. Conclusion: Blood glucose increases with a very high increase in blood pressure, whereas for a carbohydrate diet, there is no guarantee that a high diet will be able to reduce blood glucose significantly. This may be affected by the patient's saturation of a very high carbohydrate diet.

INTERARM SYSTOLIC BLOOD PRESSURE DIFFERENCE IS ASSOCIATED WITH A HIGH PREVALENCE OF CARDIO VASCULAR DISEASES- A CROSS-SECTIONAL STUDY IN POLICE WORKER

2020 ◽  
Vol 4 (11) ◽  
Author(s):  
Somesh Raju ◽  
Rina Kumari ◽  
Sunita Tiwari ◽  
NS Verma
Keyword(s):  
Blood Pressure ◽  
Systolic Blood Pressure ◽  
Blood Sugar ◽  
Pressure Difference ◽  
Systolic Pressure ◽  
Working Environment ◽  
Vascular Events ◽  
Cross Sectional ◽  
Blood Pressure Difference ◽  
High Prevalence

Background: Interarm systolic blood pressure difference more than 10 mm of Hg is predictor of cardiovascular and metabolic risk. Despite of sufficient physical activity there is high prevalence of obesity in police personal because of stressful working environment. No studies have addressed the significance of interarm pressure difference among them. Therefore, the present study conducted to access the relation of interarm blood pressure difference with obesity in police personnel. Aims and Objective: To estimate the interarm pressure difference in police personal to see its association with their obesity. Material and Method: This cross-sectional observational study done on 245 police workers in PAC, Sitapur, India. Subjects having more than ten years of working experience were included in study. Anthropometric measurements of subject recorded by following standard protocol. Measurement of systolic pressure in both arm recorded simultaneously by mercury sphygmomanometer. Available data analyze and expressed in percentage, mean with SD and chi square test to see the significance of association. Results: According to anthropometric results of subjects 77.14 prcent subjects were having generalised obesity and 82.04 percent of subjects having abdominal obesity. 34.29 percent of subjects showed abnormally high (?10 mmHg) inter-arm systolic blood pressure difference. Both type of obesity showed positive association with blood sugar level but no association with interarm pressure difference. Conclusion: Interarm blood pressure difference is greater in individual having obesity or prolong duration of service. Such subjects are more susceptible to develop coronary artery disease or peripheral arterial disease in future. Early screening can help to detect the vascular events likely to occur in the future Keywords: Body mass index, Waist circumference, Interarm pressure difference, Random blood sugar

Descending Cervical-Sacral Pain after the Administration of Antivenom to the Scorpion Sting Poisoning: A Case Report

2020 ◽  
Vol 2 (2) ◽  
pp. 93-96
Author(s):  
Josué Saúl Almaraz Lira ◽  
Alfredo Luis Chávez Haro ◽  
Cristian Alfredo López López ◽  
Remedios del Pilar González Jiménez
Keyword(s):  
Blood Pressure ◽  
Type 2 Diabetes ◽  
Case Report ◽  
Signs And Symptoms ◽  
Cervical Region ◽  
Scorpion Sting ◽  
Case Presentation ◽  
Sacral Region ◽  
Scorpion Stings

Introduction. Scorpion stings occur mainly in spring and summer, with an estimate of 1.2 million cases per year worldwide. About 300,000 poisonings occur within a year, primarily affecting children and adults older than 65 years. In 2019, Guanajuato (Mexico) ranked third in poisoning by scorpion sting with a total of 43,913 cases. The intoxication grades are three where the signs and symptoms are varied. There are two types of antivenom in the Mexican market, and we use Alacramyn® in our case. Case presentation. A 70-year-old female —with grade 1 scorpion sting poisoning, 30 minutes of evolution, with type 2 diabetes and high blood pressure— received two vials of antivenom according to current regulations. She presented transient vagal reaction and subsequent transient pain in the cervical region that radiates to the sacral region. At discharge, there are no data compatible with scorpion sting poisoning. Conclusions. Transient pain in the cervical region to the sacral region may be secondary to an anxiety crisis, hypersensitivity to IgG, or secondary reaction to administration in less time than recommended by the provider. The benefit was greater than the reactions that occurred.

scholarly journals Immediate rehabilitation with feeding appliance of a three day old neonate with cleft lip and palate- a case report

2017 ◽  
Vol 13 (2) ◽  
pp. 293-295
Author(s):  
Deepika Kapoor ◽  
Deepanshu Garg
Keyword(s):  
Case Report ◽  
Cleft Lip ◽  
Multidisciplinary Approach ◽  
Cleft Lip And Palate ◽  
Facial Growth ◽  
Orofacial Clefts ◽  
High Incidence ◽  
Negative Effect ◽  
Growth Development ◽  
Very High

Orofacial clefts (OFC) are one of the most common congenital problems seen with a very high incidence. It imparts a negative effect on the overall health of the child by hindering in his feeding practices, normal facial growth, development of dentition and hence speech. Infants born with orofacial clefts have oronasal communication which creates a problem with the creation of negative pressure inside the oral cavity required for suckling.The treatment for such patients is with the multidisciplinary approach but the preliminary  concern for the neonate is to help with the feeding for which a feeding appliance is given. This case report presents a case of a 3-day old infant to whom a feeding appliance was given to aid in suckling. 

Jumpstarting Health With a 15-Day Whole-Food Plant-Based Program

2021 ◽  
pp. 155982762110063
Author(s):  
Susan M. Friedman ◽  
Carol Hee Barnett ◽  
Robert Franki ◽  
Bruce Pollock ◽  
Beth Garver ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Systolic Blood Pressure ◽  
Blood Sugar ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Food Plant ◽  
Fasting Blood Sugar ◽  
Average Weight ◽  
Low Density ◽  
Average Drop

The 15-day Jumpstart was developed as an evidence-based, affordable, standardized, replicable, and scalable program, designed to demonstrate quickly to patients that changing what they eat can improve their health. The program was designed using the principles of the self-determination theory of motivation and personality. Patients were instructed to eat an Esselstyn-compliant, whole-food plant-based diet consisting of vegetables, fruits, whole grains, and legumes. Of the 389 participants in the program from September 2018 to February 2020, average weight loss was 5.8 pounds (7.3 for those whose body mass index was >30), average systolic blood pressure drop was 6.8 points (16.8 points for those with systolic blood pressure >140), average drop in cholesterol was 26 points (44 points for those with a cholesterol >200), average drop in low-density lipoprotein was 19 points (33 points for those with a low-density lipoprotein >100), and average drop in fasting blood sugar was 5.1 points (28.4 points for those starting in the diabetic range); P value was <.005 for fasting blood sugar and <.001 for all other comparisons. A 15-day program that helps patients adopt an Esselstyn-style whole-food plant-based diet, through education, individualized medical feedback, social support, and facilitated small group work, rapidly improves health.

scholarly journals Effects of AGXT2 variants on blood pressure and blood sugar among 750 older Japanese subjects recruited by the complete enumeration survey method

BMC Genomics ◽  
2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Yuta Yoshino ◽  
Hiroshi Kumon ◽  
Takaaki Mori ◽  
Taku Yoshida ◽  
Ayumi Tachibana ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Blood Pressure ◽  
Blood Sugar ◽  
Vascular Diseases ◽  
Survey Method ◽  
Nucleotide Polymorphisms ◽  
Complete Enumeration ◽  
Plasma Adma ◽  
Oxide Synthase ◽  
Japanese Subjects

Abstract Background Alanine:glyoxylate aminotransferase 2 (AGXT2; EC 2.6.1.44) is the only enzyme that degrades the R-form of 3-aminoisobutyrate, an intermediate metabolite of thymine. AGXT2, as well as diaminoarginine dimethylaminohydrolase 1 (DDAH1; EC 3.5.3.18), works as an enzyme that degrades asymmetric dimethylarginine (ADMA), which competitively inhibits the nitric oxide synthase family. Thus, these two enzyme activities may change vascular vulnerability for a lifetime via the nitric oxide (NO) system. We investigated the association between vascular conditions and diseases such as hypertension and diabetes mellitus and polymorphisms of these two genes in 750 older Japanese subjects (mean age ± standard deviation, 77.0 ± 7.6 years) recruited using the complete enumeration survey method in the Nakayama study. Demographic and biochemical data, such as blood pressure (BP) and casual blood sugar (CBS), were obtained. Four functional single nucleotide polymorphisms (SNPs; rs37370, rs37369, rs180749, and rs16899974) of AGXT2 and one functional insertion/deletion polymorphism in the promotor region with four SNPs (rs307894, rs669173, rs997251, and rs13373844) of DDAH1 were investigated. Plasma ADMA was also analyzed in 163 subjects. Results The results of multiple regression analysis showed that a loss of the functional haplotype of AGXT2, CAAA, was significantly positively correlated with BP (systolic BP, p = 0.034; diastolic BP, p = 0.025) and CBS (p = 0.021). No correlation was observed between DDAH1 and either BP or CBS. ADMA concentrations were significantly elevated in subjects with two CAAA haplotypes compared with subjects without the CAAA haplotype (p = 0.033). Conclusions Missense variants of AGXT2, but not DDAH1, may be related to vulnerability to vascular diseases such as hypertension and DM via the NO system.

scholarly journals Asymptomatic mediastinal extra-adrenal paraganglioma as a cause of sudden death: a case Report

2019 ◽  
Vol 14 (1) ◽  
pp. 564-567
Author(s):  
Qiancheng Xu ◽  
Yingya Cao ◽  
Hongzhen Yin ◽  
Rongrong Wu ◽  
Tao Yu ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Case Report ◽  
Respiratory Failure ◽  
Pressure Drop ◽  
Thoracic Cavity ◽  
Severe Hypotension ◽  
Life Threatening ◽  
History Of ◽  
Posterior Mediastinal ◽  
Extra Adrenal Paraganglioma

AbstractA 23-year-old female patient was referred for treatment of a posterior mediastinal tumour. There was no history of hypertension or headache and no other complaints. The patient’s blood pressure increased to 210/125 mmHg after surgically manipulating the tumour, subsequently reversing to severe hypotension (25/15 mmHg) immediately after the tumour was removed. The life-threatening and irreversible blood pressure drop was difficult to treat with fluid and vasopressors, and the patient ultimately died of cardio-respiratory failure. Asymptomatic paraganglioma can be non-functional but can also be fatal. For any lump in the thoracic cavity, paraganglioma should be ruled out.

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